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Medication  Non-Adherence: The Hidden Epidemic Managing Medication Adherence & A Safe Hospital  Discharge   David R Donohue, M.A., Qualitative Technologies, Inc. Milwaukee, WI Dr. Tom Muscarello, Ph D, DePaul University, Chicago, IL
Incidence of Medication Noncompliance ,[object Object],[object Object],Henry J Kaiser Family Foundation, 2009
U.S. Patients Do Not Take Medications as Prescribed American Heart Association: Statistics you need to know.  http://216.185.102.50/CAP/pro/prof_statistics2.html .  Accessed July 27, 2009.   100% 76%* 88% 47%* Rx prescribed Rx continued Rx taken Rx filled -12% -12% -29% *  22% of U.S. patients take less of the medication than is prescribed
Impact of Medication Adherence on Hospitalization Risk *P<0.05 when compared to the 80-100% group Hospitalization   Risk Sokol etal. Med Care  2005;43: 521-530
Impact of Medication Adherence on All-Cause Healthcare Costs *P<0.05 when compared to the 80-100% group  + P<0.05 when compared to the 80-100% group in Diabetes and Hypercholesterolemia Patients Sokol etal. Med Care  2005;43: 521-530
Potential Barriers to  Improving Adherence  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Vermiere E, et al.  J Clin Pharm Ther.   2007;26:331-342.
What is  CMAG? ,[object Object],[object Object],[object Object]
WHO White Paper on Adherence ,[object Object],Adherence to Long-Term Therapies: Evidence for Action. WHO 2003
CMAG Algorithm Case Management Adherence Guidelines. Copyright ©  2005. CMSA
CMAG Assessment Tools ,[object Object],[object Object],[object Object],[object Object]
Health Literacy ,[object Object],[object Object],[object Object]
Bass Pf, Wilson JF, Griffith, CH.  J Gen Intern Med.2003 ;18:1036-1038 .
Medication Knowledge  Survey   ,[object Object],[object Object]
 
CMAG Assessment Tools ,[object Object],[object Object],[object Object]
Readiness Ruler ,[object Object],Zimmerman GL, Olsen CG, Bosworth MF.  Am Fam Physician .2000:61;1409-1416
Social Support ,[object Object],[object Object],[object Object],Broadhead WE, et al. Med Care.2006:27;221-223.
 
Modified Morisky Scale ,[object Object],[object Object],[object Object],[object Object],Morisky DE, Green LW, Levine DM.  Med Care . 1986;24:67-74.
 
New to CMAG Revision Recognize unique needs of those working successfully with inpatients Hospital Discharge
The Hospitalized Patient ,[object Object],[object Object],[object Object]
Successful Discharge ,[object Object]
Steps  to Ensure a  Successful Discharge ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Information for Patients  to Ensure a  Successful Discharge ,[object Object],[object Object]
Information for Patients  to Ensure a  Successful Discharge ,[object Object],[object Object]
Questions  Addressed With Patients Prior To Discharge ,[object Object],[object Object],[object Object],[object Object],[object Object]
Why discharge counseling and adherence messaging are important for the hospital?   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Competitive Advantage for Hospital Discharge Planning ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Current State of Hospital Discharge Counseling and Adherence Messaging ,[object Object],[object Object],[object Object],[object Object],[object Object],King, 1998;  Makaryus, 2005
Key Elements of Successful Discharge Planning ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],AHA, Get with the Guidelines
Coordination of Care and Transition of Care Outside the Hospital
Transition of Care to the  Outpatient Setting ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Medication Non Adherence X

  • 1. Medication Non-Adherence: The Hidden Epidemic Managing Medication Adherence & A Safe Hospital Discharge David R Donohue, M.A., Qualitative Technologies, Inc. Milwaukee, WI Dr. Tom Muscarello, Ph D, DePaul University, Chicago, IL
  • 2.
  • 3. U.S. Patients Do Not Take Medications as Prescribed American Heart Association: Statistics you need to know. http://216.185.102.50/CAP/pro/prof_statistics2.html . Accessed July 27, 2009. 100% 76%* 88% 47%* Rx prescribed Rx continued Rx taken Rx filled -12% -12% -29% * 22% of U.S. patients take less of the medication than is prescribed
  • 4. Impact of Medication Adherence on Hospitalization Risk *P<0.05 when compared to the 80-100% group Hospitalization Risk Sokol etal. Med Care 2005;43: 521-530
  • 5. Impact of Medication Adherence on All-Cause Healthcare Costs *P<0.05 when compared to the 80-100% group + P<0.05 when compared to the 80-100% group in Diabetes and Hypercholesterolemia Patients Sokol etal. Med Care 2005;43: 521-530
  • 6.
  • 7.
  • 8.
  • 9. CMAG Algorithm Case Management Adherence Guidelines. Copyright © 2005. CMSA
  • 10.
  • 11.
  • 12. Bass Pf, Wilson JF, Griffith, CH. J Gen Intern Med.2003 ;18:1036-1038 .
  • 13.
  • 14.  
  • 15.
  • 16.
  • 17.
  • 18.  
  • 19.
  • 20.  
  • 21. New to CMAG Revision Recognize unique needs of those working successfully with inpatients Hospital Discharge
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32. Coordination of Care and Transition of Care Outside the Hospital
  • 33.

Notas del editor

  1. Reference: Henry J Kaiser Family Foundation, 2009. The effect of patient noncompliance on health care costs. Intent of Slide: Increase audience awareness of the prevalence of medication noncompliance in the U.S. Expand upon the opportunities available for the pharmacist to intervene and increase medication compliance through patient counseling and follow-up.
  2. This is a conceptual slide, based on statistics from the American Heart Association. Here you can see non adherence broken down by behavior and quantified. As you can see, there is a progression of non adherence that starts with not filling the prescription (12%). Then there are those that fill the prescription, but do not take the medication (12%). Then there are those who take the medication, but do not persist with it (29%). And within the percentage of patients that take their medications, there are 22% that take less than is prescribed. So according to this information, only 25% of those who are prescribed medication actually take it like they should. How does this affect patients?
  3. The impact of medication adherence on the estimated all-cause hospitalization risk based on regression analysis. Results indicated that the outcome was significantly higher than the outcome for the 80-100% group (P&lt;0.05) In the public debate over sky rocketing prescription drug costs the potential economic return s are often missed. These results demonstrate that a net return may be obtained for 3 chronic conditions that account for a large share of long term medication use. In this slide statistically significant different differences were seen in the hospitalization risk in patients that had a lower adherence level compared to those with adherence levels from 80-100% Other Notes: The study consisted of 137,277 patients under age 65 Measures included disease related and all cause medical costs, drug costs and hospitalization risk were measured. Using regression analysis these measure were modeled at varying levels of medication adherence. Medication adherence was defined by days’ supply of maintenance medications for each condition.
  4. The estimated all-cause healthcare costs based on regression analysis In the public debate over sky rocketing prescription drug costs the potential economic returns are often missed. These results demonstrate that a net return may be obtained for 3 chronic conditions that account for a large share of long term medication use. In this slide statistically significant different differences were seen in the hospitalization risk in patients that had a lower adherence level compared to those with adherence levels from 80-100% Other Notes: The study consisted of 137,277 patients under age 65. Measures included disease related and all cause medical costs, drug costs and hospitalization risk were measured. Using regression analysis these measures were modeled at varying levels of medication adherence. Medication adherence was defined by days’ supply of maintenance medications for each condition.
  5. Some of these barriers are more easily overcome than others. (i.e. support can be provided externally but cultural and religious beliefs are deeply ingrained and difficult to bridge).
  6. Collaboration is vital to ensure that the appropriate patients are referred to case management. Therefore, case managers need to work closely with other healthcare professional to ensure appropriate referral.
  7. CMAG 2 has coined the term Successful Discharge for patients receiving appropriate Discharge Planning services. Patients that receive the appropriate steps that lead to a Successful Discharge will be more likely to manage their disease outside the hospital. This will decrease the chances of the person needing to be readmitted to the hospital for acute exacerbations of chronic conditions and complications related to procedures. Since hospitalization is frequently the most expensive part of the treatment, this should help control overall healthcare expenditures.
  8. There are many individuals that may be involved in the discharge planning process. These individuals can be divided into lay individuals that provide support for the patients and those that are involved with the provision of healthcare services.  
  9. Involvement of family and friends especially important for interventions involving lifestyle modifications. Thank you, David R Donohue, M.A. and Dr Tom Muscarello, Ph D, DePaul University, Chicago, IL