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Syncope:
Krishnakumar D
AVMC&H
Syncope:
I. Introduction
II. Classification
III. Etiology
IV. Diagnosis
V. Treatment
VI. Special Issues
Syncope – A Symptom, Not a Diagnosis:
• Sudden transient loss of consciousness with associated loss of
postural tone,
• Relatively rapid onset,
• Variable warning symptoms,
• Spontaneous, complete, and usually prompt recovery without
medical or surgical intervention.
Underlying mechanism is
transient global cerebral hypoperfusion.
Syncope:
• Syncope as a symptoms can be caused by a variety of medical
diseases that produce a transient interruption of cerebral blood flow.
• A genuine effort should be made to determine a specific cause of
syncope as identifying a specific cause can help in the selection of
therapy, prevent recurrences, minimize expensive evaluations, and
decrease morbidity.
• Patients with cardiac syncope have higher rates of mortality and
sudden death at follow up.
• Identifying and treating cardiac syncope can improve outcome.
• Real or Apparent TLOC
Syncope
Neurally-mediated reflex
syndromes
Orthostatic hypotension
Cardiac arrhythmias
Structural cardiovascular disease
Disorders Mimicking
Syncope
With loss of
consciousness, i.e.,
seizure disorders,
concussion
Without loss of
consciousness, i.e.,
psychogenic “pseudo-
syncope”
Causes of True Syncope:
Neutrally-Mediated
 VVS
 Situational
 Cough
 Post-
 Micturition
Orthostatic
 Drug-Induced
 • ANS Failure
 Primary
 Secondary
Cardiac Arrhythmia
 Brady
 SN Dysfunction
 Causes of True Syncope AV Block Tachy
 VT
 SVT
 Long QT Syndrome
Structural Cardio- Pulmonary
 Acute Myocardial Ischemia
 Aortic Stenosis
 Pulmonary Hypertension
 Aortic Dissection
Clinical Features:
• Prior faintness
• Dizziness or light-headedness occurs in 70% of patients experiencing true syncope.
• Vertigo
• Diaphoresis
• Weakness
• Diaphoresis
• Epigastric discomfort
• Nausea
• Blurred or faded vision
• Pallor
• Paresthesia
Investigation:
• Serum glucose level
• CBC count
• Serum electrolyte levels with renal function
• Urinalysis/dipstick
Imaging:
oChest radiography
oBrain MRI/magnetic resonance arteriography (MRA)
oEchocardiography
Pre-hospital management:
• Airway-Advanced airway techniques
• Breathing-High flow Oxygen, If needed assist ventilation
Circulation
• Intravenous access
• Advanced airway techniques
• Glucose administration
• Pharmacologic circulatory support
• Pharmacologic or mechanical restraints
• Defibrillation or temporary pacing
Syncope1.pptx

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Syncope1.pptx

  • 2. Syncope: I. Introduction II. Classification III. Etiology IV. Diagnosis V. Treatment VI. Special Issues
  • 3. Syncope – A Symptom, Not a Diagnosis: • Sudden transient loss of consciousness with associated loss of postural tone, • Relatively rapid onset, • Variable warning symptoms, • Spontaneous, complete, and usually prompt recovery without medical or surgical intervention. Underlying mechanism is transient global cerebral hypoperfusion.
  • 4. Syncope: • Syncope as a symptoms can be caused by a variety of medical diseases that produce a transient interruption of cerebral blood flow. • A genuine effort should be made to determine a specific cause of syncope as identifying a specific cause can help in the selection of therapy, prevent recurrences, minimize expensive evaluations, and decrease morbidity. • Patients with cardiac syncope have higher rates of mortality and sudden death at follow up. • Identifying and treating cardiac syncope can improve outcome.
  • 5. • Real or Apparent TLOC Syncope Neurally-mediated reflex syndromes Orthostatic hypotension Cardiac arrhythmias Structural cardiovascular disease Disorders Mimicking Syncope With loss of consciousness, i.e., seizure disorders, concussion Without loss of consciousness, i.e., psychogenic “pseudo- syncope”
  • 6. Causes of True Syncope: Neutrally-Mediated  VVS  Situational  Cough  Post-  Micturition Orthostatic  Drug-Induced  • ANS Failure  Primary  Secondary Cardiac Arrhythmia  Brady  SN Dysfunction  Causes of True Syncope AV Block Tachy  VT  SVT  Long QT Syndrome Structural Cardio- Pulmonary  Acute Myocardial Ischemia  Aortic Stenosis  Pulmonary Hypertension  Aortic Dissection
  • 7. Clinical Features: • Prior faintness • Dizziness or light-headedness occurs in 70% of patients experiencing true syncope. • Vertigo • Diaphoresis • Weakness • Diaphoresis • Epigastric discomfort • Nausea • Blurred or faded vision • Pallor • Paresthesia
  • 8. Investigation: • Serum glucose level • CBC count • Serum electrolyte levels with renal function • Urinalysis/dipstick Imaging: oChest radiography oBrain MRI/magnetic resonance arteriography (MRA) oEchocardiography
  • 9. Pre-hospital management: • Airway-Advanced airway techniques • Breathing-High flow Oxygen, If needed assist ventilation Circulation • Intravenous access • Advanced airway techniques • Glucose administration • Pharmacologic circulatory support • Pharmacologic or mechanical restraints • Defibrillation or temporary pacing