Cervical intraepithelial neoplasia (cin) is precancerous condition in which abnormal cell growth occurs on the surface lining of the cervix or endocervical canal, the opening between the uterus and the vagina.

1. Cervical Intraepithelial Neoplasia
(CIN)

2. Cervical Intraepithelial Neoplasia
(CIN)
Cervical intraepithelial neoplasia is a precancerous condition
in which abnormal cell growth occurs on the surface lining of
the cervix or endocervical canal, the opening between the
uterus and the vagina. It is also known as cervical dysplasia.
Strongly connected with sexually transmitted human
papillomavirus (HPV) infection, cervical intraepithelial
neoplasia is most common in women under age 30 but can
develop at any age.
Cervical intraepithelial neoplasia usually causes no symptoms,
and is most often discovered by a routine Pap smear test. The
outlook is positive for women with cervical intraepithelial
neoplasia who receive appropriate follow-up and treatment.
But women who go undiagnosed or who don't receive
appropriate care are at higher risk of developing cervical
cancer.

3. Cervical Intraepithelial Neoplasia
(CIN)
Mild cervical intraepithelial neoplasia sometimes
resolves without treatment, and may only require careful
observation with Pap tests every three or six months.
But moderate to severe and mild cervical intraepithelial
neoplasia that persists for two years normally requires
treatment to remove the abnormal cells and reduce the
risk of cervical cancer.
Continue:

4. Causes of cervical intraepithelial
neoplasia
In many women with cervical intraepithelial neoplasia, human
papillomavirus is found in cervical cells. HPV infection is
common in women and men, and most often affects sexually
active women under age 20.
In most cases, the immune system eliminates HPV and clears
the infection. But in some women, the infection persists and
leads to cervical intraepithelial neoplasia.
Among women with a chronic HPV infection, smokers are
twice as likely as non-smokers to develop severe cervical
dysplasia, because smoking suppresses the immune system.
Chronic HPV infection and cervical intraepithelial neoplasia are
also associated with other factors that weaken the immune
system, such as treatment with immunosuppressive drugs for
certain diseases or after an organ transplant, or infection with
HIV, the virus that causes AIDS.

5. Symptoms
Risk factors for cervical intraepithelial neoplasia
Persistent HPV infection is the most important risk
factor for cervical dysplasia, especially moderate to
severe cervical intraepithelial neoplasia. In women,
an increased risk of a persistent HPV infection is
associated with:
 Early initiation of sexual activity
 Having more than one sex partner
 Having a partner who has had multiple sex partners
 Having sex with an uncircumcised man

6. Diagnosis of cervical intraepithelial
neoplasia
Because a pelvic exam is usually normal in women with
cervical intraepithelial neoplasia, a Pap test is necessary
to diagnose the condition.
Although a Pap test alone can identify mild, moderate, or
severe cervical intraepithelial neoplasia, further tests are
often required to determine appropriate follow-up and
treatment. These include:
 Repeat Pap tests
 Colposcopy, a magnified exam of the cervix to detect
abnormal cells so that biopsies can be taken
 Endocervical curettage, a procedure to check for
abnormal cells in the cervical canal

7. Diagnosis of cervical intraepithelial
neoplasia
 Cone biopsy or loop electrosurgical excision
procedure (LEEP) which is performed to rule out
invasive cancer during a cone biopsy, the doctor
removes a cone-shaped piece of tissue for lab
examination. During LEEP, the doctor cuts out
abnormal tissue with a thin, low-voltage electrified
wire loop
 HPV DNA test, which can identify the HPV strains
which are known to cause cervical cancer
Continue:

8. Treatments
The treatment for cervical intraepithelial
neoplasia depends on many different factors, including
the severity of the condition and the age of the patient.
For mild cervical intraepithelial neoplasia, often only
continued monitoring with repeat Pap tests is needed.
For older women with mild cervical intraepithelial
neoplasia, usually no treatment is needed unless mild
cervical intraepithelial neoplasia has persisted for two
years, progressed to moderate or severe cervical
dysplasia, or there are other medical problems.
Treatments for cervical intraepithelial neoplasia include
two of the procedures also used for diagnosis
cone biopsy or LEEP. Other treatments include:
 Cryosurgery (freezing)

9. Treatments
 Electrocauterization
 Laser surgery
 Because all forms of treatment are associated with
risks such as heavy bleeding and possible
complications affecting pregnancy, it's important for
patients to discuss these risks with their doctor
prior to treatment.
Continue:

10. CONNECT WITH US
Logon to
www.lazoi.com
Like us on Facebook
https://www.facebook.com/LazoiTheLife
Follow us on Twitter
https://www.twitter.com/lazoithelife
Follow us on Pinterest
https://www.in.pinterest.com/lazoithelife