Neuroblastoma is a rare disease in which a solid tumour caused by uncontrolled or abnormal cell growth is formed by special nerve cells called neuroblasts.

1. NEUROBLASTOMA
Information on symptoms,
diagnosis and treatment options

2. INTRODUCTION TO NEUROBLASTOMA
• Cancer of the sympathetic
nervous system which affects
approximately 600 children a
year and the average age of
diagnosis is 3 yrs.
• Stage IV Neuroblastoma is very
aggressive and chances of
survival are 30%. NB has one
of the highest rates of relapse
among any cancers, and when
it does come back, chances of
survival are 5%

3. SING AND SYMPTOMS OF NEUROBLASTOMA
Signs and symptoms of
neuroblastoma vary depending on
what part of the body is affected.
Symptoms of neuroblastoma in
the abdomen are:
• Abdominal pain
• A mass under the skin that
isn't tender when touched
• Changes in bowel habits, such
as diarrhoea
• Swelling in the legs

4. SING AND SYMPTOMS OF NEUROBLASTOMA
Symptoms of neuroblastoma
in the chest are:
• Wheezing
• Chest pain
• Drooping eyelids and
unequal pupil size
• Enlarged liver
• Fatigue

5. SING AND SYMPTOMS OF NEUROBLASTOMA
Other signs of neuroblastoma
include:
• Lumps of tissue under the
skin
• Eyeballs that seem to
protrude from the sockets
• Dark circles, similar to
bruises, around the eyes
• Back pain
• Unexplained weight loss
• Bone pain

6. TESTS AND DIAGNOSIS OF
NEUROBLASTOMA
If your doctor suspects neuroblastoma, he may suggest the
following tests and procedures to diagnose
neuroblastoma:
• Full body check-up: Your child's doctor conducts a
physical exam to check out any signs and symptoms.
• Urine and blood tests: These tests may identify the
cause of any signs and symptoms your child is
experiencing. Urine tests may be used to check for
high levels of certain chemicals that result from the
neuroblastoma cells producing excess catecholamine.

7. • Imaging tests: Imaging tests such as X-ray, ultrasound,
computerized tomography (CT)
scan, metaiodobenzylguanidine (MIBG) scan and magnetic
resonance imaging (MRI) may reveal a mass that can
indicate a tumour.
• Removing a sample of tissue for testing: If a mass is found,
your child's doctor may want to remove a sample of the
tissue for laboratory testing which is medically known as
biopsy. This helps the doctor devise an individualized
treatment plan.
• Removing a sample of bone marrow for testing: Your child
may also undergo bone marrow biopsy and bone marrow
aspiration procedures to see if neuroblastoma has spread to
the bone marrow.
TESTS AND DIAGNOSIS OF
NEUROBLASTOMA

8. TREATMENT OPTIONS FOR
NEUROBLASTOMA
The doctors are very selective in choosing the treatment plan
because it can affect your child’s prognosis. There are various
treatment options for neuroblastoma, including:
• Surgery: Oncologists use various surgical tools to remove
cancer cells. In children with low-risk neuroblastoma,
surgery to remove the tumour may be the only treatment
needed.
• Chemotherapy: Chemotherapy uses chemicals to destroy
cancer cells. This therapy attacks rapidly growing cells in
the body, including cancer cells. Children with moderate
neuroblastoma often receive a combination of
chemotherapy drugs before surgery.

9. TREATMENT OPTIONS FOR
NEUROBLASTOMA
• Radiation therapy: Radiation therapy uses high-energy
beams to execute cancer cells. Children with low to
moderate risk of neuroblastoma may receive radiation
therapy if surgery and chemotherapy haven't been
helpful.
• Stem cell transplant: Children with high-risk
neuroblastoma may receive a transplant using their own
blood stem cells.
• Immunotherapy: This therapy uses drugs that work by
stimulating your body's immune system to help fight
cancer cells.

10. CONNECT WITH US
Logon to
www.lazoi.com
Like us on facebook
https://www.facebook.com/LazoiTheLife
Follow us on Twitter
https://twitter.com/lazoithelife
Follow us on Pinterest
https://in.pinterest.com/lazoithelife/