Purified Omega 7 Palmitoleic Acid is a "Medical Breakthrough" that is clinically shown to reduce C-Reactive Protein (CRP), and prevent the buildup of atherosclerotic plaque by optimizing cholesterol and reducing inflammation in the arteries.

2. Overview
 Tersus Pharmaceuticals
 Provinal® Purified Omega
7
 Scientific Overview
 The Business Opportunity
 Regulatory Situation
 Timeline to Market

3. Tersus Pharmaceuticals
 Founded in 2009
 In 2010, Tersus was recipient of “Affordable
Care Act Grants to Support Groundbreaking
Biomedical Research”
 In 2011, conducted research, launched
Provinal®, and built a global and scalable
supply chain
 In 2012, launched several products,
conducted more research, and Dr. Michael
F. Roizen became Chairman of Scientific
Advisory Board

4. The high cost of poor health
 Chronic disease has overtaken
infectious disease as #1 threat
globally
 1 of 2 people die of heart attack or
stroke and never knew what hit them
 More than $1 trillion wasted annually
in the U.S. alone (as well as loss of
life and productivity)

5. Provinal® - Scientific Overview
 The Cleveland Clinic Study

6. Purifying Palmitoleic Acid
 Palmitoleic Acid (C16:1n7)
 Macadamia Nuts
 Sea Buckthorn
 Fish Oil

7. Purifying Palmitoleic Acid
 The word “napalm” is derived from the words
naphthenic acid and palmitic acid

8. Purifying Palmitoleic Acid
 "Design is the first
signal of human
intention” ~ William
McDonough, Cradle
to Cradle
 WHO places palmitic
acid in the same
category of
cardiovascular risk as
transfat: “How much
transfat would you like
in your supplement?”
Source: World Health
Organization

9. Fatty Acid Profiles: Fish Oil vs. Krill Oil

10. Fatty Acid Profiles: Superba vs. Provinal®
0
10
20
30
40
50
60
Active Ingredient Palmitic Acid
34.1
21.8
51.4
0.5
Superba (o-3)
Provinal (o-7)

11. Provinal® - Business Opportunity
 CVD
 Not just
cholesterol &
triglycerides
but
inflammation
 Attacks multiple pathways to combat:
Atherosclerosis, Diabetes, Metabolic Syndrome, Fatty Liver

12. Provinal® - Business Opportunity
0
10
20
30
40
50
60
70
Avg CRP
Reduction
Avg TG
Reduction
Avg LDL
Reduction
Avg HDL
Increase
67
36
10.3 4.2
Omega 7 Clinical Trial
% Change for 16 Subjects in one month
taking 210 mg/day
A clinical trial was conducted
by Dr. Luis Martinez at the
Xyrion Physician Training and
Specialty Clinic in Puerto
Rico. Dr. Martinez is a Board
Certified Lipidologist, Anti-
Aging and Regenerative
Medicine Specialist, residency
trained in
Preventive, Occupational, and
Environmental Medicine.
This small clinical – a pre-
curser to a larger 54
person, double-blind, placebo
controlled experiment.

13. Provinal vs Vascepa (AMR)

14. Provinal® - Business Opportunity
0%
10%
20%
30%
40%
50%
60%
70%
Lovaza (4g) Algal DHA
(7.5g)
Krill Oil (3g) Vascepa (4g) Palmitoleic
Acid
(210mg)
1%
15% 17% 22%
67%
Comparison to Omega 3 Products
Avg Reduction CRP in one month

15. Provinal® - Summary of Benefits
 Lowers C-reactive protein ("CRP" -
which measures inflammation in the
body)
 Lowers trigylcerides and hepatic fat
accumulation,
 Lowers bad cholesterol, and
 Increases good cholesterol.

16. The Business Opportunity: “5 areas in
arterial aging YOU can impact”
1. Endothelial & Grout Injury/dysfunction
2. Quality of LDL Repair
3. Chronic Inflammation
4. Acute Inflammation/Rupture
5. Platelet/Clot Aggregation on injury
~ Dr. Michael F. Roizen, MD

17. 5 areas in arterial aging YOU can
impact with Aspirin:
1. Endothelial & Grout Injury/dysfunction
2. Quality of LDL Repair
3. Chronic Inflammation
4. Acute Inflammation/Rupture
5. Platelet/Clot Aggregation on injury
~ Dr. Michael F. Roizen, MD

18. 5 areas in arterial aging YOU can
impact with Aspirin & Omega 7:
1. Endothelial & Grout Injury/dysfunction
2. Quality of LDL Repair
3. Chronic Inflammation
4. Acute Inflammation/Rupture
5. Platelet/Clot Aggregation on injury
~ Dr. Michael F. Roizen, MD

19. Provinal® - Regulatory Situation
 GRAS Certified by AIBMR
 Structure Function Claims
 Helps maintain normal triglycerides *
 Helps maintain normal C-reactive
protein (CRP) levels *

20. Provinal® - Time to Market
 The raw materials required to
produce Provinal® are:
 abundant,
 sustainable, and
 scalable
– and the company has secured a global
supply.