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By: Dr. Lindsay Rosenwald
 An entrepreneur and investor in the biotechnology
industry, Dr. Lindsay Rosenwald has helped numerous
pharmaceutical companies to research and develop
highly effective drugs.
 As a co-founder and original financial supporter of
Cougar Biotechnology, Dr. Lindsay Rosenwald oversaw
the company as it developed the drug Zytiga, which
produced unprecedented results in patients with end-
stage and untreatable prostate cancer.
 In the field of oncology, cancer staging helps patients
and physicians to classify the severity of a cancer
diagnosis.
 In addition to helping a physician develop an
appropriate course of treatment, it also facilitates
prognosis and identifies patients for suitable clinical
trials.
 Staging systems typically depend on a number of common
elements, including the spread of cancer to the lymph
nodes, location of the primary tumor, tumor size, and the
number of tumors.
 The TNM staging system, one of the most commonly used
by physicians today, classifies cancer based on tumor
extent, spread to lymph nodes, and the presence of
metastasis.
 Based on the TNM evaluation, a physician can then place a
patient’s cancer diagnosis into one of five stages, which
range from Stage 0 to Stage IV.
 Stage 0 cancer represents an early cancer that has not
spread to other tissues, while stage IV cancer has typically
spread to another organ in the body.

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An Introduction to Cancer Staging

  • 1. By: Dr. Lindsay Rosenwald
  • 2.  An entrepreneur and investor in the biotechnology industry, Dr. Lindsay Rosenwald has helped numerous pharmaceutical companies to research and develop highly effective drugs.  As a co-founder and original financial supporter of Cougar Biotechnology, Dr. Lindsay Rosenwald oversaw the company as it developed the drug Zytiga, which produced unprecedented results in patients with end- stage and untreatable prostate cancer.
  • 3.  In the field of oncology, cancer staging helps patients and physicians to classify the severity of a cancer diagnosis.  In addition to helping a physician develop an appropriate course of treatment, it also facilitates prognosis and identifies patients for suitable clinical trials.
  • 4.  Staging systems typically depend on a number of common elements, including the spread of cancer to the lymph nodes, location of the primary tumor, tumor size, and the number of tumors.  The TNM staging system, one of the most commonly used by physicians today, classifies cancer based on tumor extent, spread to lymph nodes, and the presence of metastasis.  Based on the TNM evaluation, a physician can then place a patient’s cancer diagnosis into one of five stages, which range from Stage 0 to Stage IV.  Stage 0 cancer represents an early cancer that has not spread to other tissues, while stage IV cancer has typically spread to another organ in the body.