12. Humoral Response to T Independent Antigens Cell growth division, and differentiation in a lymph node Clone of many effector cells secreting antibodies ER ER ER ER Selection of B cells Triggering of the B cell
18. PRIMARY RESPONSE (initial encounter with antigen) Antigen Antigen receptor on a B cell Antigen binding to a B cell Memory B cell Antibody molecules Plasma cell Cell growth, division, and differentiation SECONDARY RESPONSE (can be years later) Cell growth,division, & further differentiation Larger clone of cells Plasma cell Antibody molecules Later exposure to same antigen Memory B cell Clone of cells