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Anemia with pregnancy
 Definition
 Is defined as a haemoglobin concentration less than
10.5gm /dl , or if hematocrit falls to less than 30%.( WHO)
 Problem in the Jordan
 Anemia during pregnancy and breast feeding is 37%.
 23%-24% have mild anemia , 13.5% have moderate ,1% have
sever anaemia.
 Degree: Mild: 8-10gm%Degree: Mild: 8-10gm%
Moderate: 7-8gm%Moderate: 7-8gm%
Severe: <7gm%Severe: <7gm%
 According to UNICEF its found that more than 28% of women
of child bearing age were anaemic in Jordan.
 Causes and predisposing factors:
1- low iron intake
 low intake of iron-rich food
 nausea and vomiting
2- Increased demand
 heavy mens
 High parity
 bleeding haemorrhoids
3- Inadequate absorption /utilization of iron
 food that have a strong inhibiting effect on iron absorption , tea ,
coffee, egg, ca++ rich foods.
 Malabsorption syndrome.
 Decreased HCL.
4- increased iron requirements:
 Increased demand from growing fetus , placenta.
 Low internal between 1st
and 2nd
pregnancy
 Effects of anemia on pregnancy :
 Maternal :
 abruptio placenta may be associated with maternal anaemia.
 high risk for PPH.
 High risk for infection puerperal sepsis.
 Poor lactation is often a consequence of anaemia.
 High risk of developing shock and death if Hge occur during
child birth (potential threat to life) .
 Reduced enjoyment of pregnancy and mother hood of to
fatigue.
 Fetal :
- increased of still birth neonatal deaths if
maternal Hb% decreased 8%.
-Increased incidence of pre-term labour.
-increased incidence of IUGR and hypoxia
** Note : the most common forms of anemia
are caused by deficiencies in iron and folic
acid.
Nurse role in the assessment of
women with anemia in pregnancy
 History taking: hx of any of the predisposing
factors.
 symptoms of anemia :
 C.V.S palpitation.
 C.N.S headache , visual disturbance , weakness ,
fatigability , drowsiness.
 R.S breathlessness.
 G.I.S anorexia , nausea , vomiting.
 G.U.S loss of libido.
Conjunctival PallorConjunctival Pallor
 Physical exam :
 General exam  pallor of the skin and mucous of
membrane , tachycardia, tiredness.
 Abdominal exam fundal height : less than the
gestational age
 Investigations :
 Laboratory investigation
 CBC and RBC
 HB < 10.5 gm/dl.
  RBC concentration < 5x10^6 /mm^3
  hypochromic & microcytic.
Normal Iron Requirements
 Iron requirement for normal pregnancy is 1gm
200 mg is excreted
300 mg is transferred to fetus
500 mg is need for mother
 Total volume of RBC inc is 450 ml
1 ml of RBCs contains 1.1 mg of iron
450 ml X 1.1 mg/ml = 500 mg
 Daily average is 6-7 mg/day
 Blood film.
 Reticulocytic count.
 Serous ferritin level.
 Ultrasound to check gestational age ,
placental site , amount of liqour & any
congenital fetal malformation.
 Normal hemoglobin by gestational age inNormal hemoglobin by gestational age in
pregnant women taking iron supplementpregnant women taking iron supplement
 12 wks12 wks 12.2 [11.0-13.4]12.2 [11.0-13.4]
 24wks24wks 11.6 [10.6-12.8]11.6 [10.6-12.8]
 40 wks40 wks 12.6 [11.2-13.6]12.6 [11.2-13.6]
Intervention in pregnant women with
anemia
 Prophylactic
 Importance of antenatal visits
 Encourage to attend the scheduled antenatal visit and explain
the importance of preventing & treating anemia in pregnancy.
 Educate the mother regarding the sources of food rich in iron &
folic acid , sea food , fruit , meat, egg , green vegetables.
 Advice to avoid poor eating habits & intake of enhancers of iron
absorption such as fruit , vegetables , vit C
 Iron supplementation  is very important during pregnancy & it
should be emphasized on all antenatal visits.
TreatmentTreatment
 Prophylactic: Supplement Fe – 60 mg: Supplement Fe – 60 mg
elemental Fe with Folic Acidelemental Fe with Folic Acid
 CurativeCurative: 200mg FeSo4 3 times daily till: 200mg FeSo4 3 times daily till
Hb level becomes normal, thenHb level becomes normal, then
maintenance dose of 1 tab formaintenance dose of 1 tab for
100 days100 days
 WHO recommended for iron supplementation
for any pregnant women :
 All pregnant women should be given the
standard dose of iron or folate (tab of 30 mg
iron + 400 mg folic acid/day ) every day  for
women with normal iron stores for 6 months
during pregnancy and continuing post partum
 Avoid iron supplement during 1st
trimester and
give after nausea subsided.
Curative and management of anemia
 Oral supplementation ferrous sulphate
 Parenteral iron therapy.
1. When diagnosed late in pregnancy
2. Malabsorption
3. Gastric intolerance to oral iron
 Blood transfusion
 During blood transfusion :monitor uterine activity ,
FM , FHR
 Plus routine observation
Natal and post natal care:
 Assess the Hb prior to delivery
 Give blood if Hb% decreased 10.5 mg/dl.
 Prevent infection.
 Insure adequate hydration.
 Practice an active management of 3rd
stage.
of labour advise to seek contraception.
Sickle cell anemia
 An inherited disorder caused by abnormal Hb% in
the blood (abnormal shape) lead to hypoxia ,
dehydration ,infection , fatigue crisis
 Effect on the pregnancy :
 Effect on the organs and placenta blockage of
vessels & infarcts in organs , blockage to the
placenta , circulation occurs lead to fetal death &
increase risk for abortion.
Management
 Blood transfusion to maintain hematocrit
increased 30%.
 Management during labour
 O2 supplement
 I.V fluid
 fetal monitoring
 antibiotic if C/S birth
Effects on pregnancyEffects on pregnancy
 Increase incidence of abortion, prematurity,Increase incidence of abortion, prematurity,
IUGR and Fetal loss.IUGR and Fetal loss.
 Perinatal mortality is high.Perinatal mortality is high.
 Incidence of pre-eclampsia, postpartumIncidence of pre-eclampsia, postpartum
hemorrhage and infection is increased.hemorrhage and infection is increased.
Thalasemia
 Abnormal Hb  haemolysis
 Risk for infection.
 Avoid iron accumulation by using
chelating factor.
 Monitor fetal and maternal condition.
Folic acid deficiency anemia
(megaloplastic anemia(
 Folic acid is needed for increased cell growth of both mother
and fetus (necessary in all body cells synthesis DNA)
 Occurs as a result of inadequate intake , poor absorption ,
increased use & poor cooking habits.
 Decreased folic associated with decreased B12 vit
 Decreased folic acid associated with decreased iron mainly
 Occurs in the last trimester due to increased demand &
decreased intake
Pernicious anemia (vit B12 deficiency(
 In adequate intake  vegetarian
 Common in elderly person & females

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Anemia with pregnancy

  • 2.  Definition  Is defined as a haemoglobin concentration less than 10.5gm /dl , or if hematocrit falls to less than 30%.( WHO)  Problem in the Jordan  Anemia during pregnancy and breast feeding is 37%.  23%-24% have mild anemia , 13.5% have moderate ,1% have sever anaemia.  Degree: Mild: 8-10gm%Degree: Mild: 8-10gm% Moderate: 7-8gm%Moderate: 7-8gm% Severe: <7gm%Severe: <7gm%  According to UNICEF its found that more than 28% of women of child bearing age were anaemic in Jordan.
  • 3.  Causes and predisposing factors: 1- low iron intake  low intake of iron-rich food  nausea and vomiting 2- Increased demand  heavy mens  High parity  bleeding haemorrhoids 3- Inadequate absorption /utilization of iron  food that have a strong inhibiting effect on iron absorption , tea , coffee, egg, ca++ rich foods.  Malabsorption syndrome.  Decreased HCL.
  • 4. 4- increased iron requirements:  Increased demand from growing fetus , placenta.  Low internal between 1st and 2nd pregnancy  Effects of anemia on pregnancy :  Maternal :  abruptio placenta may be associated with maternal anaemia.  high risk for PPH.  High risk for infection puerperal sepsis.  Poor lactation is often a consequence of anaemia.  High risk of developing shock and death if Hge occur during child birth (potential threat to life) .  Reduced enjoyment of pregnancy and mother hood of to fatigue.
  • 5.  Fetal : - increased of still birth neonatal deaths if maternal Hb% decreased 8%. -Increased incidence of pre-term labour. -increased incidence of IUGR and hypoxia ** Note : the most common forms of anemia are caused by deficiencies in iron and folic acid.
  • 6. Nurse role in the assessment of women with anemia in pregnancy  History taking: hx of any of the predisposing factors.  symptoms of anemia :  C.V.S palpitation.  C.N.S headache , visual disturbance , weakness , fatigability , drowsiness.  R.S breathlessness.  G.I.S anorexia , nausea , vomiting.  G.U.S loss of libido.
  • 8.  Physical exam :  General exam  pallor of the skin and mucous of membrane , tachycardia, tiredness.  Abdominal exam fundal height : less than the gestational age  Investigations :  Laboratory investigation  CBC and RBC  HB < 10.5 gm/dl.   RBC concentration < 5x10^6 /mm^3   hypochromic & microcytic.
  • 9. Normal Iron Requirements  Iron requirement for normal pregnancy is 1gm 200 mg is excreted 300 mg is transferred to fetus 500 mg is need for mother  Total volume of RBC inc is 450 ml 1 ml of RBCs contains 1.1 mg of iron 450 ml X 1.1 mg/ml = 500 mg  Daily average is 6-7 mg/day
  • 10.  Blood film.  Reticulocytic count.  Serous ferritin level.  Ultrasound to check gestational age , placental site , amount of liqour & any congenital fetal malformation.
  • 11.  Normal hemoglobin by gestational age inNormal hemoglobin by gestational age in pregnant women taking iron supplementpregnant women taking iron supplement  12 wks12 wks 12.2 [11.0-13.4]12.2 [11.0-13.4]  24wks24wks 11.6 [10.6-12.8]11.6 [10.6-12.8]  40 wks40 wks 12.6 [11.2-13.6]12.6 [11.2-13.6]
  • 12. Intervention in pregnant women with anemia  Prophylactic  Importance of antenatal visits  Encourage to attend the scheduled antenatal visit and explain the importance of preventing & treating anemia in pregnancy.  Educate the mother regarding the sources of food rich in iron & folic acid , sea food , fruit , meat, egg , green vegetables.  Advice to avoid poor eating habits & intake of enhancers of iron absorption such as fruit , vegetables , vit C  Iron supplementation  is very important during pregnancy & it should be emphasized on all antenatal visits.
  • 13. TreatmentTreatment  Prophylactic: Supplement Fe – 60 mg: Supplement Fe – 60 mg elemental Fe with Folic Acidelemental Fe with Folic Acid  CurativeCurative: 200mg FeSo4 3 times daily till: 200mg FeSo4 3 times daily till Hb level becomes normal, thenHb level becomes normal, then maintenance dose of 1 tab formaintenance dose of 1 tab for 100 days100 days
  • 14.  WHO recommended for iron supplementation for any pregnant women :  All pregnant women should be given the standard dose of iron or folate (tab of 30 mg iron + 400 mg folic acid/day ) every day  for women with normal iron stores for 6 months during pregnancy and continuing post partum  Avoid iron supplement during 1st trimester and give after nausea subsided.
  • 15. Curative and management of anemia  Oral supplementation ferrous sulphate  Parenteral iron therapy. 1. When diagnosed late in pregnancy 2. Malabsorption 3. Gastric intolerance to oral iron  Blood transfusion  During blood transfusion :monitor uterine activity , FM , FHR  Plus routine observation
  • 16. Natal and post natal care:  Assess the Hb prior to delivery  Give blood if Hb% decreased 10.5 mg/dl.  Prevent infection.  Insure adequate hydration.  Practice an active management of 3rd stage. of labour advise to seek contraception.
  • 17. Sickle cell anemia  An inherited disorder caused by abnormal Hb% in the blood (abnormal shape) lead to hypoxia , dehydration ,infection , fatigue crisis  Effect on the pregnancy :  Effect on the organs and placenta blockage of vessels & infarcts in organs , blockage to the placenta , circulation occurs lead to fetal death & increase risk for abortion.
  • 18.
  • 19. Management  Blood transfusion to maintain hematocrit increased 30%.  Management during labour  O2 supplement  I.V fluid  fetal monitoring  antibiotic if C/S birth
  • 20. Effects on pregnancyEffects on pregnancy  Increase incidence of abortion, prematurity,Increase incidence of abortion, prematurity, IUGR and Fetal loss.IUGR and Fetal loss.  Perinatal mortality is high.Perinatal mortality is high.  Incidence of pre-eclampsia, postpartumIncidence of pre-eclampsia, postpartum hemorrhage and infection is increased.hemorrhage and infection is increased.
  • 21. Thalasemia  Abnormal Hb  haemolysis  Risk for infection.  Avoid iron accumulation by using chelating factor.  Monitor fetal and maternal condition.
  • 22. Folic acid deficiency anemia (megaloplastic anemia(  Folic acid is needed for increased cell growth of both mother and fetus (necessary in all body cells synthesis DNA)  Occurs as a result of inadequate intake , poor absorption , increased use & poor cooking habits.  Decreased folic associated with decreased B12 vit  Decreased folic acid associated with decreased iron mainly  Occurs in the last trimester due to increased demand & decreased intake
  • 23. Pernicious anemia (vit B12 deficiency(  In adequate intake  vegetarian  Common in elderly person & females