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Advanced Drug Delivery Markets (Liposomes, Polymers and
Monoclonal Antibodies)
December 1, 2010
Drug delivery is evolving at a rapid rate with new drug product formulations being
discovered frequently. Advanced drug delivery deals with developing solutions for new
entities in therapeutic pharmacology such as protein and peptides and other novel
compounds targeting drugs to specific disease sites including gene therapy. Treatments
for chronic conditions and growth in patient-administered drugs are factors leading to
greater focus on ease-of-use and convenience.
Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies)
details the types of drug delivery systems, technologies and products utilizing advanced
drug delivery systems The report describes the industry, its relationship to various
healthcare channels, and the trends for the future.
The advanced drug delivery market is two-fold. First of all it identifies drug delivery
technology Secondly, it identifies products in the pharmaceutical arena that utilize those
drug delivery technologies. Because drug delivery technology is an integral part of sales
of pharmaceuticals and drug delivery technology cannot exist without pharmaceuticals,
revenues have been reported that include pharmaceutical sales. This report will provide
market data that includes the pharmaceutical revenues of those products that utilize
advanced drug delivery.
In this report, the advanced drug delivery market is divided into three main segments
and market estimates are provided for indications within each category:
Liposome Drug Delivery (by Indication - Fungal Infections Cancer, Others)
Polymer Drug Delivery (by Indication - Cancer, Neutropenia, Hepatitis,
Contraception, Schizophrenia, Acromegaly and Others)
Monoclonal Antibodies Drug Delivery (by Indication - Arthritis, Cancer,
Multiple Sclerosis, Macular Degeneration, Respiratory Syncytial Virus, Others)
The following types of polymer delivery drugs are segmented within this report.
PEGylated Delivery
Emulsuion Delivery
Injectable Delivery

2. Nanoparticle Delivery
Others
A wide range of trends and issues that will impact the advance drug delivery market are
discussed in the report including the current state of biotechnolgy expansion, molecular
imprinted polymers, hot-melt extrusion, metallofullerenes, nanotechnology
advancements and other emerging Drug Delivery technologies not yet on the market.
The following companies are profiled in the report:
Alkermes, Inc.
ALZA Corporation
AP Pharma
Centocor Ortho Biotech, Inc.
Eisai , Inc
Elan Corporation, Plc
EnColl Corporation, Inc.
Enzon Pharmaceuticals, Inc
Gilead Sciences, Inc.
Nektar Therapeutics
PDL BioPharma
pSivida Corp
SurModics, Inc
Tolmar, Inc
The research conducted by Kalorama Information included comprehensive research of
primary and secondary sources such as interviews with company executives, company
literature, databases, investment reports, and medical and business journals. New
technologies, market developments, and research and development trends and
expenditures were identified through patent and data-based searches, as well as via
interviews with key personnel. Person-to-person and telephone interviews were the
primary method of gathering information. E-mail correspondence was also used in the
interview process. Interviews with 24 key industry officials, trade association
spokespersons, consultants, healthcare providers, and government personnel were
compiled to form the primary basis of information - particularly revenue and market
share data- presented in this report.
All market data pertains to the worldwide market at the manufacturers’ level and was
measured in U.S. dollars. The base year for data was 2010. Historical data are provided
for 2006 through 2009, with forecast data provided for 2010 through 2014. Compound
annual growth rates (CAGR) are provided for the 2006-2010, 2010-2014 and 2006-
2014.
CHAPTER ONE: EXECUTIVE SUMMARY

3. Overview
Market Drivers
Market Size and Growth
Market Trends
CHAPTER TWO: INTRODUCTION AND OVERVIEW
Introduction
Scope and Methodology
Reasons for Advanced Drug Delivery Systems
Phases of Drug Action
CHAPTER THREE: LIPOSOME DRUG DELIVERY
Overview
Liposome Targeting
Passive Targeting
Active Targeting
New Developments
Market Summary
Liposome Market by Indication
Liposome Market Competitive Analysis
CHAPTER FOUR: POLYMER DRUG DELIVERY
Overview
Polymeric Implants
Biodegradable Polymers
Nano- and Microparticulates
Polymer Micelles
PEGylation Technology
Hydrogel Polymers
Colloidal systems
PLA, PLG, and PLGA
Emulsions
Proteinaceous microparticles
New Developments
Market Summary
Market for Polymers by Product Type
Polymer Market by Indication
Polymer Market Competitive Analysis
CHAPTER FIVE: MONOCLONAL ANTIBODY DRUG DELIVERY
Overview

4. New Developments
Market Summary
Monoclonal Antibody Market by Indication
Monoclonal Antibody Market Competitive Analysis
CHAPTER SIX: TRENDS AND TECHNOLOGY DEVELOPMENTS
Expansion of Biotechnology
Incorporation of Technology
Molecular Imprinted Polymers
Antibiotic Biodegradable Implants
Hot-melt Extrusion Technology
Sorbent Technology
Gene Therapy Drug Delivery
Metallofullerenes
Antisense Delivery Systems
Nanotechnology advancements
Camouflaged Nanoparticles
Triggerable Drug Delivery
Prodrug Drug Delivery
Single Chain Antigen-Binding Protein Technology
Heat Shock Protein Technology
Other Emerging Drug Delivery Technologies
CHAPTER SEVEN: MARKET SIZE AND GROWTH
Total Market Summary
Geographical Market Growth Summary Competitive Growth Analysis
CHAPTER EIGHT: COMPANY PROFILES
Alkermes, Inc.
ALZA Corporation
AP Pharma
Centocor Ortho Biotech, Inc.
Eisai , Inc
Elan Corporation, Plc
EnColl Corporation, Inc.
Enzon Pharmaceuticals, Inc
Gilead Sciences, Inc.
Nektar Therapeutics
PDL BioPharma
pSivida Corp
SurModics, Inc
Tolmar, Inc

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