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Clinical vignette 1 
Multiple injury 
Hwmo 
Maryam AL-Qahtani. 
G:3
Hemorrhagic shock 
is a condition of reduced tissue perfusion, 
resulting in the inadequate delivery of oxygen 
and nutrients that are necessary for cellular 
function.
Objectives: 
Describe in detail how this patient's body 
would compensate for his primary problem. 
Is this patient's urinary output normal?
How this patient's 
body would 
compensate for his 
primary problem?
The body’s response: 
Compensated Shock. 
Decompensated Shock. 
Irreversible Shock.
Compensated Shock. 
These are the main mechanisms used 
to compensate the patient’s condition 
: 
1- The baroreceptor reflex. 
2- Increased sympathetic nervous system 
stimulation. 
3- Renin-angiotensin-aldosterone (R-A-A) axis.
Compensated Shock. 
Baroreceptor reflex: 
Blood volume 
Systemic arterial blood 
pressure
Increased sympathetic nervous system stimulation helps 
to maintain systemic blood pressure in the following 
ways: 
1/ Increasing the contractility of the heart....> 
increasing stroke volume. 
2/ Increasing the frequency of action potentials ......> 
increasing the heart rate.
3/This increases the resistance ....> 
raising blood pressure. 
4/contraction of smooth muscle in the 
systemic veins.....> increasing the rate 
of return of venous blood to the heart( 
increases the pre-load and thus stroke 
volume of the heart.)
Renin-angiotensin-aldosterone 
(R-A-A) 
axis.
Urinary Output 
(Normal or abnormal)
Case: 
Urinary output =20ml per hour. 
Normal 
value: 
Range of 30- 50 ml per hour.
In general : 
hemorrhagic shock 
Reduce blood flow to the kidneys 
Making it difficult for the kidneys to cleanse the 
bloodstream of waste products and to obtain 
enough oxygen and nutrients for its own 
metabolic needs.
Quiz
One of these body response is not one of 
compensate for hemorrhagic : 
Increase heart rate 
Increase blood pressure 
Decrease stroke volume
Normal value of urinary output 
=
Compensated Shock: 
Early stages of shock where the body’s compensatory 
mechanisms are able to maintain normal perfusion . 
.Normal range of urinary output 30-50 ml per hour.
Guyton & Hall. Text book of Medical physiology . 
.Merck Manual. 
.Up to data. Website 
http://classes.midlandstech.edu/carterp/Courses/bio211/chap19/ 
chap19.html 
http://www.ccmtutorials.com/cvs/shock/page_5.5.htm
trauma and bleeding (hemorrhagic shock)

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trauma and bleeding (hemorrhagic shock)

  • 1. Clinical vignette 1 Multiple injury Hwmo Maryam AL-Qahtani. G:3
  • 2. Hemorrhagic shock is a condition of reduced tissue perfusion, resulting in the inadequate delivery of oxygen and nutrients that are necessary for cellular function.
  • 3. Objectives: Describe in detail how this patient's body would compensate for his primary problem. Is this patient's urinary output normal?
  • 4. How this patient's body would compensate for his primary problem?
  • 5. The body’s response: Compensated Shock. Decompensated Shock. Irreversible Shock.
  • 6. Compensated Shock. These are the main mechanisms used to compensate the patient’s condition : 1- The baroreceptor reflex. 2- Increased sympathetic nervous system stimulation. 3- Renin-angiotensin-aldosterone (R-A-A) axis.
  • 7. Compensated Shock. Baroreceptor reflex: Blood volume Systemic arterial blood pressure
  • 8.
  • 9. Increased sympathetic nervous system stimulation helps to maintain systemic blood pressure in the following ways: 1/ Increasing the contractility of the heart....> increasing stroke volume. 2/ Increasing the frequency of action potentials ......> increasing the heart rate.
  • 10. 3/This increases the resistance ....> raising blood pressure. 4/contraction of smooth muscle in the systemic veins.....> increasing the rate of return of venous blood to the heart( increases the pre-load and thus stroke volume of the heart.)
  • 11.
  • 13.
  • 14. Urinary Output (Normal or abnormal)
  • 15. Case: Urinary output =20ml per hour. Normal value: Range of 30- 50 ml per hour.
  • 16. In general : hemorrhagic shock Reduce blood flow to the kidneys Making it difficult for the kidneys to cleanse the bloodstream of waste products and to obtain enough oxygen and nutrients for its own metabolic needs.
  • 17. Quiz
  • 18. One of these body response is not one of compensate for hemorrhagic : Increase heart rate Increase blood pressure Decrease stroke volume
  • 19.
  • 20.
  • 21. Normal value of urinary output =
  • 22.
  • 23. Compensated Shock: Early stages of shock where the body’s compensatory mechanisms are able to maintain normal perfusion . .Normal range of urinary output 30-50 ml per hour.
  • 24. Guyton & Hall. Text book of Medical physiology . .Merck Manual. .Up to data. Website http://classes.midlandstech.edu/carterp/Courses/bio211/chap19/ chap19.html http://www.ccmtutorials.com/cvs/shock/page_5.5.htm

Notas del editor

  1. Compensated Shock: Early stages of shock where the body’s compensatory mechanisms are able to maintain normal perfusion . Decompensated Shock: Advanced stage of shock that occurs when the body’s compensatory mechanisms fail to maintain normal perfusion. Irreversible Shock: Stage of shock that has progressed to the point that the body nor medical interventions correct the problem.
  2. Compensated Shock.
  3. If mean arterial pressure rises, baroreceptors in the carotid SINUS and aortic arch detect stretch and send impulses to the vasomotor center, inhibiting its activity and promoting vasodilation of arterioles and veins. They also stimulate the cardioinhibitory center and inhibit the cardioacceleratory center when stretched, reducing cardiac output. A drop in mean arterial pressure causes vasocontriction and increased cardiac ouput. The carotid SINUS reflex protects blood flow to the brain, while the aortic reflex maintains blood pressure throughout the systemic circuit.
  4. C-This increases the resistance ....> raising blood pressure. D. contraction of smooth muscle in the systemic veins.....> increasing the rate of return of venous blood to the heart( increases the pre-load and thus stroke volume of the heart.)
  5. This patient's blood volume and blood pressure should be increased so that he does not develop acute renal failure.