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Semantic AI for Healthcare
The HORUS.AI Platform
Mauro Dragoni
Fondazione Bruno Kessler
Process and Data Intelligence Research Unit
Health and Wellbeing High Impact Initiative
18th International Semantic Web Conference
Auckland, New Zealand
October 26th, 2019
1 introduction
2 background & challenges
3 the HORUS.AI system
4 living labs and discussion
agenda
two words about myself
page
03
design of a real-time
reasoning strategy
Health &
Wellbeing
working on the
virtual coach project
definition of conceptual
models for Digital Health
FBK since
2011
a bit of business
processes
sentiment analysis
knowledge
management
Ph.D. in 2010
information retrieval
natural language
processing
our goal
page
04
To design a virtual coaching system supporting people
and physicians in real-time monitoring and
recommendation activities.
virtual coaching state of the art
page
05
horizontal
strategies
behavior change persuasive models barriers management
vertical
strategies
living
labs
specific
problem
use of
canned
text
fixed
intervention
challenges
page
06
 C1: to design a strategy that is flexible.
AI and health
page
07
medical imaging
AI strategies applied to the
analysis of x-rays, MRI, etc..
genomics
Application of data science
techniques for analyzing the
interactions between drugs and
genetic profiles.
diagnosis
Use of intelligent agents for
understanding the health
status of people.
chronic diseases
Supporting people in managing
their chronic diseases with
intelligent solutions.
personalized medicine
Design of AI-based solutions
tailored with patients history and
profile.
prevention
Monitoring people for avoid the
onset or the worsen of specific
diseases.
AI and virtual coaching
page
08
chronic diseases
Supporting people in managing
their chronic diseases with
intelligent solutions.
personalized medicine
Design of AI-based solutions
tailored with patients history and
profile.
prevention
Monitoring people for avoid the
onset or the worsen of specific
diseases.
AI Models
challenges
page
09
 C1: to design a strategy that is flexible.
 C2: to provide a knowledge-driven explainable model.
the persuasive framework
page
010
Prescription Persuasion
Guidelines-
based system
Coaching system
the persuasive framework
page
011
Harm op den Akker et al.: Tailored motivational message generation: A model and practical framework for real-time physical activity coaching.
Journal of Biomedical Informatics 55: 104-115 (2015)
challenges
page
012
 C1: to design a strategy that is flexible.
 C2: to provide a knowledge-driven explainable model.
 C3: to integrate the psychological dimension.
engaging users
page
013
challenges
page
014
 C1: to design a strategy that is flexible.
 C2: to provide a knowledge-driven explainable model.
 C3: to integrate the psychological dimension.
 C4: to reduce users effort.
the Semantic XAI paradigm
page
015
To understand the status
and the goals of a user.
To aggregate and analyze data
and knowledge coming from:
- users;
- experts;
- domain.
To support an engaging
communication with users
and physicians through
time.
the Semantic XAI paradigm
sense
page
016
structured data (patients’ logs, sensors, images, etc.).
task-oriented conversational agents.
interactions with closed answers.
application of NLP and IE strategies to open answers.
application of NLU strategies to open answers.
chat-bots supporting argumentation.
the Semantic XAI paradigm
think
page
017
definition of the supporting conceptual model.
design of real-time reasoning strategies.
integration of external knowledge and data sources.
synergy with external machine learning models.
the Semantic XAI paradigm
act
page
018
use of canned messages.
dynamic generation of messages.
support for multi-modal feedback.
integration of full-fledged behavior change policies.
our virtual coach history
page
019
21 3 4
2015: the idea
We started to discuss which were the
requirements of an effective virtual
coaching system and to design the first
prototype.
2016: first living lab
The prototype of the virtual coaching
system was used within a living lab on
Workplace Health Promotion
2017: first deployment
The virtual coaching platform was
deployed in the context of the Trentino
Salute 4.0 framework and used, through a
mobile application, by more than 4,000
users.
2018: evolution
The virtual coaching platform has been
partially redesigned for making it more
flexible and connectable from third-
parties.
2019: HORUS.AI
the HORUS.AI platform
page
020
the HORUS.AI platform
the knowledge layer
page
021
the knowledge layer
reasoner
page
022
 Two kind of entailment rules:
• Event-Based Rules (EB-Rules): evaluated in real-time after a user event is sent by users;
• Timespan-Based Rules (TB-Rules): evaluated in background on specific timestamp basis.
 Aspects of interest:
• non-monotonic reasoning;
• generation of new individuals;
• per-user reasoning.
the knowledge layer
the reasoning process
page
023
the knowledge layer
population of the knowledge base with undesired behaviors
page
024
the HORUS.AI platform
the persuasive layer
page
025
the persuasive layer
message generator process
page
026
Violation
Read
Feedback
Generation
Argument
Extraction
Suggestion
Integration
the persuasive layer
violation bean
page
027
Violation
Read
Feedback
Generation
Argument
Extraction
Suggestion
Integration
the persuasive layer
feedback generation
page
028
Violation
Read
Feedback
Generation
Argument
Extraction
Suggestion
Integration
feedback := temporal adverb + feed verb + adjective + quantity + food entity
Language
Persuasive
strategy
the persuasive layer
argument extraction
page
029
Violation
Read
Feedback
Generation
Argument
Extraction
Suggestion
Integration
argument := intro + food entity category + verb adjective + food property + consequent verb + consequence
Language
Persuasive
strategy
the persuasive layer
suggestion integration
page
030
Violation
Read
Feedback
Generation
Argument
Extraction
Suggestion
Integration
suggestion := introduction + food entity + alternative
Language
Persuasive
strategy
living lab
page
031
 The Key To Health project.
 120 users have been monitored for 7 weeks.
• 92 users in the intervention group;
• 28 users in the control group.
 We observed and reported the effectiveness of generated explanations.
evaluation
page
032
 Three kind of entailment
rules:
• QB-Rules (EB-Rules)
• DAY-RULES and WEEK-
RULES (TB-Rules)
challenges addressed
page
033
 C1: to design a strategy that is flexible.
 C2: to provide a knowledge-driven explainable model.
 C3: to integrate the psychological dimension.
 C4: to reduce users effort.
future work
page
034
 Extension of the knowledge base.
 Integration of HORUS.AI in more living labs.
 Investigation about the implementation of stream reasoning strategies.
 Extension of the reasoner with fuzzy capabilities.
 Learning monitoring rules adaptation by means of learning techniques.
contacts
page
035
Mauro Dragoni
dragoni@fbk.eu
thank you.

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Keynote given at ISWC 2019 Semantic Management for Healthcare Workshop

  • 1. Semantic AI for Healthcare The HORUS.AI Platform Mauro Dragoni Fondazione Bruno Kessler Process and Data Intelligence Research Unit Health and Wellbeing High Impact Initiative 18th International Semantic Web Conference Auckland, New Zealand October 26th, 2019
  • 2. 1 introduction 2 background & challenges 3 the HORUS.AI system 4 living labs and discussion agenda
  • 3. two words about myself page 03 design of a real-time reasoning strategy Health & Wellbeing working on the virtual coach project definition of conceptual models for Digital Health FBK since 2011 a bit of business processes sentiment analysis knowledge management Ph.D. in 2010 information retrieval natural language processing
  • 4. our goal page 04 To design a virtual coaching system supporting people and physicians in real-time monitoring and recommendation activities.
  • 5. virtual coaching state of the art page 05 horizontal strategies behavior change persuasive models barriers management vertical strategies living labs specific problem use of canned text fixed intervention
  • 6. challenges page 06  C1: to design a strategy that is flexible.
  • 7. AI and health page 07 medical imaging AI strategies applied to the analysis of x-rays, MRI, etc.. genomics Application of data science techniques for analyzing the interactions between drugs and genetic profiles. diagnosis Use of intelligent agents for understanding the health status of people. chronic diseases Supporting people in managing their chronic diseases with intelligent solutions. personalized medicine Design of AI-based solutions tailored with patients history and profile. prevention Monitoring people for avoid the onset or the worsen of specific diseases.
  • 8. AI and virtual coaching page 08 chronic diseases Supporting people in managing their chronic diseases with intelligent solutions. personalized medicine Design of AI-based solutions tailored with patients history and profile. prevention Monitoring people for avoid the onset or the worsen of specific diseases. AI Models
  • 9. challenges page 09  C1: to design a strategy that is flexible.  C2: to provide a knowledge-driven explainable model.
  • 10. the persuasive framework page 010 Prescription Persuasion Guidelines- based system Coaching system
  • 11. the persuasive framework page 011 Harm op den Akker et al.: Tailored motivational message generation: A model and practical framework for real-time physical activity coaching. Journal of Biomedical Informatics 55: 104-115 (2015)
  • 12. challenges page 012  C1: to design a strategy that is flexible.  C2: to provide a knowledge-driven explainable model.  C3: to integrate the psychological dimension.
  • 14. challenges page 014  C1: to design a strategy that is flexible.  C2: to provide a knowledge-driven explainable model.  C3: to integrate the psychological dimension.  C4: to reduce users effort.
  • 15. the Semantic XAI paradigm page 015 To understand the status and the goals of a user. To aggregate and analyze data and knowledge coming from: - users; - experts; - domain. To support an engaging communication with users and physicians through time.
  • 16. the Semantic XAI paradigm sense page 016 structured data (patients’ logs, sensors, images, etc.). task-oriented conversational agents. interactions with closed answers. application of NLP and IE strategies to open answers. application of NLU strategies to open answers. chat-bots supporting argumentation.
  • 17. the Semantic XAI paradigm think page 017 definition of the supporting conceptual model. design of real-time reasoning strategies. integration of external knowledge and data sources. synergy with external machine learning models.
  • 18. the Semantic XAI paradigm act page 018 use of canned messages. dynamic generation of messages. support for multi-modal feedback. integration of full-fledged behavior change policies.
  • 19. our virtual coach history page 019 21 3 4 2015: the idea We started to discuss which were the requirements of an effective virtual coaching system and to design the first prototype. 2016: first living lab The prototype of the virtual coaching system was used within a living lab on Workplace Health Promotion 2017: first deployment The virtual coaching platform was deployed in the context of the Trentino Salute 4.0 framework and used, through a mobile application, by more than 4,000 users. 2018: evolution The virtual coaching platform has been partially redesigned for making it more flexible and connectable from third- parties. 2019: HORUS.AI
  • 21. the HORUS.AI platform the knowledge layer page 021
  • 22. the knowledge layer reasoner page 022  Two kind of entailment rules: • Event-Based Rules (EB-Rules): evaluated in real-time after a user event is sent by users; • Timespan-Based Rules (TB-Rules): evaluated in background on specific timestamp basis.  Aspects of interest: • non-monotonic reasoning; • generation of new individuals; • per-user reasoning.
  • 23. the knowledge layer the reasoning process page 023
  • 24. the knowledge layer population of the knowledge base with undesired behaviors page 024
  • 25. the HORUS.AI platform the persuasive layer page 025
  • 26. the persuasive layer message generator process page 026 Violation Read Feedback Generation Argument Extraction Suggestion Integration
  • 27. the persuasive layer violation bean page 027 Violation Read Feedback Generation Argument Extraction Suggestion Integration
  • 28. the persuasive layer feedback generation page 028 Violation Read Feedback Generation Argument Extraction Suggestion Integration feedback := temporal adverb + feed verb + adjective + quantity + food entity Language Persuasive strategy
  • 29. the persuasive layer argument extraction page 029 Violation Read Feedback Generation Argument Extraction Suggestion Integration argument := intro + food entity category + verb adjective + food property + consequent verb + consequence Language Persuasive strategy
  • 30. the persuasive layer suggestion integration page 030 Violation Read Feedback Generation Argument Extraction Suggestion Integration suggestion := introduction + food entity + alternative Language Persuasive strategy
  • 31. living lab page 031  The Key To Health project.  120 users have been monitored for 7 weeks. • 92 users in the intervention group; • 28 users in the control group.  We observed and reported the effectiveness of generated explanations.
  • 32. evaluation page 032  Three kind of entailment rules: • QB-Rules (EB-Rules) • DAY-RULES and WEEK- RULES (TB-Rules)
  • 33. challenges addressed page 033  C1: to design a strategy that is flexible.  C2: to provide a knowledge-driven explainable model.  C3: to integrate the psychological dimension.  C4: to reduce users effort.
  • 34. future work page 034  Extension of the knowledge base.  Integration of HORUS.AI in more living labs.  Investigation about the implementation of stream reasoning strategies.  Extension of the reasoner with fuzzy capabilities.  Learning monitoring rules adaptation by means of learning techniques.

Notas del editor

  1. not replacing physicians improving data analytics capacity
  2. horizontal: very theoretical, not practice implementation  not possible to have a tangible validation of what was described in the papers vertical: very specific and hard to port on different scenarios  not general enough for reducing the work of applying different coaching strategies depending on the scenario and on the user
  3. 2015: 2016: 2017: 2018: scientific (integration of dynamic persuasive policies) and technological evolution