particle size schedules spurious drugs cosmetic adulterated drugs misbranded drugs drug encapsulation efficiency in vitro ph weight uniformity pulmonary parentral transdermal nasal buccal oral blood brain barrier capillary endothelial intestinal epithelial biological tertiary secondary primary peptide protein base acid in vitro dissolution robustness drug content water titration method dilution method ternary phase diagram solubility oils co-surfactants surfactants smedds latent heat vapour pressure evaporation boiling point melting point pseudomorphism polymorphism solid liquid gaseous states of matter valves propellant meter dose inhaler aerosols pharmacology pharmaceutics ip usp monograph pharmacopoeia
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