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Diabetes Mellitus Management in CKD
Clinical Tips
Mohammed Abdel Gawad MD, ESENeph
Lecturer of Nephrology, School of Medicine, NewGiza University
Founder of NephroTube.com
ISN Education SoMe Team Member
Co-chair of AFRAN Web/Media Committee
23/March/2022
To download the lecture
contact me
drgawad@gmail.com
For more Nephrology lectures visit
www.NephroTube.com
Risk of hypoglycemia
increases with CKD
progression due to 3 causes
Renal gluconeogenesis is
impaired owing to lower
kidney mass, and the
clearance of insulin and oral
diabetes medications
decreases as CKD progresses
Anorexia and weight loss
related to uremia can also
increase hypoglycemia risk.
The risk for hypoglycemia
increases as GFR declines,
primarily in those taking
insulin, sulfonylureas, or
glinides.
Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9
Nat Rev Nephrol. 2017 Jan;13(1):11-26
Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9
https://client.globaldata.com/browse/
Diseases. 2020 May 11;8(2):14.
J Am Soc Nephrol. 2017 May 2. in press
10
Glucagon-like peptide-1 Gastric inhibitory polypeptide
Diabetologia. 2016 May;59(5):907-17
DPP4-i DPP4-i
Incretins
Incretin
mimetic
(GLP-1 RA)
Diseases. 2020 May 11;8(2):14.
Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9
Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9
Diabetes Mellitus Management in CKD (Clinical Tips) - Dr. Gawad
Diabetes Mellitus Management in CKD (Clinical Tips) - Dr. Gawad

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Diabetes Mellitus Management in CKD (Clinical Tips) - Dr. Gawad

  • 1. Diabetes Mellitus Management in CKD Clinical Tips Mohammed Abdel Gawad MD, ESENeph Lecturer of Nephrology, School of Medicine, NewGiza University Founder of NephroTube.com ISN Education SoMe Team Member Co-chair of AFRAN Web/Media Committee 23/March/2022
  • 2. To download the lecture contact me drgawad@gmail.com For more Nephrology lectures visit www.NephroTube.com
  • 3.
  • 4. Risk of hypoglycemia increases with CKD progression due to 3 causes Renal gluconeogenesis is impaired owing to lower kidney mass, and the clearance of insulin and oral diabetes medications decreases as CKD progresses Anorexia and weight loss related to uremia can also increase hypoglycemia risk. The risk for hypoglycemia increases as GFR declines, primarily in those taking insulin, sulfonylureas, or glinides. Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10. Nat Rev Nephrol. 2017 Jan;13(1):11-26
  • 11. Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9
  • 13. Diseases. 2020 May 11;8(2):14.
  • 14.
  • 15.
  • 16.
  • 17. J Am Soc Nephrol. 2017 May 2. in press 10
  • 18.
  • 19. Glucagon-like peptide-1 Gastric inhibitory polypeptide Diabetologia. 2016 May;59(5):907-17 DPP4-i DPP4-i Incretins Incretin mimetic (GLP-1 RA)
  • 20.
  • 21. Diseases. 2020 May 11;8(2):14.
  • 22. Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9
  • 23.
  • 24. Am J Kidney Dis. 2021 Sep 29;S0272-6386(21)00762-9