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Chromosomal Abnormalities
What are chromosomes? ,[object Object],This is a normal karyotype of human chromosomes. A karyotype is a picture of chromosomes lined up to look at and compare.
Chromosomal abnormalities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Chromosomal Disorders ,[object Object],[object Object],[object Object],[object Object]
Single Chromosome Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Two Chromosome Disorders ( Both types are called “translocation”) ,[object Object],[object Object],[object Object],[object Object]
Nondisjunction  ,[object Object],[object Object],[object Object],[object Object],2n n n n-1 n+1
Alteration of chromosome number
Nondisjunction  ,[object Object],[object Object],[object Object],[object Object],[object Object],trisomy 2n+1 monosomy 2n-1
Human chromosome disorders  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Down syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Trisomy 21
Sex chromosomes in different numbers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Chromosomal abnormalities