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eBook for Undergraduate Education in Radiology
Chapter Outline
CHAPTER: Ultrasound
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Preface
Undergraduate teaching of radiology in Europe is provided according to national schemes and may vary
considerably from one academic institution to another. Sometimes, the field of radiology is considered as a “cross-
cutting discipline” or taught within the context of other clinical disciplines, e.g., internal medicine or surgery.
This e-book has been created in order to serve medical students and academic teachers throughout Europe to
understand and teach radiology as a whole coherent discipline, respectively. Its contents are based on the
Undergraduate Level of the ESR European Training Curriculum for Radiology and summarize the so-called core
elements that may be considered as the basics that every medical student should be familiar with. Although
specific radiologic diagnostic skills for image interpretation cannot be acquired by all students and rather belong to
the learning objectives of the Postgraduate Levels of the ESR Training Curricula, the present e-book also contains
some further insights related to modern imaging in the form of examples of key pathologies, as seen by the
different imaging modalities. These are intended to give the interested undergraduate student an understanding of
modern radiology, reflecting its multidisciplinary character as an organ-based specialty.
We would like to extend our special thanks to the authors and members of the ESR Education Committee who
have contributed to this eBook, to Carlo Catalano, who initiated this project, and to the ESR Office, in particular
Bettina Leimberger and Danijel Lepir, for all their support in realising this project.
We hope that this e-book may fulfil its purpose as a useful tool for undergraduate academic radiology teaching.
Minerva Becker Vicky Goh
ESR Education Committee Chair ESR Undergraduate Education Subcommittee Chair
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Copyright and Terms of Use
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How to cite this work:
European Society of Radiology, Jonathan Cohen, Caroline Ewertsen (2022) eBook for Undergraduate Education
in Radiology: Ultrasound. DOI 10.26044/esr-undergraduate-ebook-08
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Hyperlinks
Core Knowledge
Further Knowledge
Compare
Questions
References
Attention
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
eBook for Undergraduate Education in Radiology
BasedontheESRCurriculumforUndergraduateRadiologicalEducation
Chapter: Ultrasound
Authors
Affiliation
Jonathan Cohen
Caroline Ewertsen
Department of Radiology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
mailjonathancohen@gmail.com
caroline.ewertsen@dadlnet.dk
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Chapter Outline
• Ultrasound Basics
 Physics
• Signal to Image
 Equipment
 Enhancing the Image
• Artifacts
 Acoustic Shadowing
 Enhancement
 Anisotropy
• The Doppler Effect
 Basic Physics
 Use in Medical Ultrasound
• Contrast Enhanced
Ultrasound
 Indications and Contraindications
• Strengths and Limitations
• Take-Home Messages
• References
• Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Sonography is a non-invasive painless procedure, which uses ultrasound waves to produce images of organs, blood
vessels or soft tissues for medical analysis. The terms sonography and ultrasound are often used interchangeably. A
sonogram is an image generated by ultrasound.
Ultrasound waves have frequencies higher than the upper limit of human hearing. In medical ultrasound, frequencies
typically fall in the 1 to 20 MHz range, while the upper limit of human hearing is around 20 kHz.
The basic ultrasound principle (Fig. 1):
• An ultrasound transducer emits an ultrasound signal.
• The transducer listens for the echo generated by the structures that the wave encounters.
• The echo is turned into an image based on characteristics of the echo, such as timing, amplitude and frequency.
Ultrasound Basics
Emitted wave
Reflected wave
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
Fig. 1 – Schematic representation of the basic ultrasound
(sonography or ultrasonography) principle.
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Ultrasound interacts with tissues in different ways:
• Reflection – waves are reflected back to the transducer.
• Absorption – waves are absorbed by the tissue and the energy is converted to heat.
• Scattering – waves are reflected in multiple different directions.
• Refraction – the direction of waves is changed
Each type of tissue has a particular impedance – a resistance to the propagation of
sound which depends on the tissue density and the speed of sound in the tissue.
The amount of generated reflection depends on differences in impedance between
tissues.
As an example, if the ultrasound wave travels from fat (low impedance) to bone (high
impedance) a large difference in impedance is encountered, and a powerful echo will be
generated.
Ultrasound Basics
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Ultrasound Basics
Structures that elicit a powerful echo appear bright on our screen – we call them hyperechoic (Fig. 2).
Structures that elicit a weak echo appear dark on our screen – we call them hypoechoic (Fig. 3).
Structures that elicit an echo similar to their surrounding structures are called isoechoic.
Fig. 2 – Cortical bone is strongly hyperechoic (green
arrow) and casts an acoustic shadow (more on that
later).
Fig. 3 – Urinary bladder filled with hypoechoic fluid (red arrow).
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Signal to Image
The ultrasound equipment generates an electrical signal (Fig. 4) which is sent through a cable to the
ultrasound transducer (sometimes called an ultrasound probe). In the transducer, an array of
piezoelectric crystals translate the signal to sound waves, which propagate from the probe outwards (Fig.
4). Piezoelectric crystals are crystals which have the ability to generate an electric charge when
mechanical pressure is applied (e.g., quartz).
The same crystals convert the returning ultrasound echo into an electrical signal, which the ultrasound
system then converts to an image.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
Fig. 4 – Schematic representation of the process by which an ultrasound image (sonogram or ultrasonogram) is generated.
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Signal to Image
Different ultrasound transducers (Fig. 5) have different strengths and limitations, and therefore different
applications. Below is an overview of the most common transducer types and their typical applications.
Curved, 1-5 MHz
Advantages: Good penetration,
wide field of view.
Disadvantages: Low resolution.
Abdominal, deep structures.
Linear, 3-12 MHz
Advantages: High resolution.
Disadvantages: Poor penetration.
Musculoskeletal, superficial
structures, neck.
Phased array, 1-5 MHz
Advantages: Wide field of view with
small transducer surface
Disadvantages: Low resolution.
Echocardiography, intercostal views.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
Fig. 5 – Advantages, disadvantages and main applications of different types of ultrasound transducers
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Signal to Image
Modern ultrasound systems continually and automatically optimize the image while you scan.
Some parameters can be adjusted by the user to further optimize the image.
• Gain: high gain increases the overall brightness of the image, but also increases noise.
• Frequency: high frequency means better image quality, but poorer penetration. Most transducers
have a set centre frequency, around which the frequency can be adjusted slightly.
• Depth: larger depth gives better overview, but details appear less visible.
• Focus: improves the appearance of the ultrasound image at the depth at which the focus is set.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Artifacts
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
Interactions between the ultrasound equipment and the body often cause artifacts. In
ultrasound, some artifacts can be used to gain information about what you are scanning.
The following slides illustrate some of the most common artifacts encountered: acoustic
shadowing, enhancement and anisotropy.
Knowledge of artifacts is imperative when performing ultrasound, as wrong interpretations of
artifacts can lead to misdiagnosis!
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Artifacts
Acoustic shadowing (Fig. 6) corresponds to low signal behind structures that strongly absorb or reflect
ultrasound waves.
Fig. 6 – Gall bladder containing multiple gall stones which display acoustic shadowing (A). In image B, acoustic
shadowing is rendered by green overlay.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
A B
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Artifacts
Enhancement (Fig. 7) corresponds to increased signal below structures that transmit sound well (e.g. fluid).
Ultrasound waves lose energy on their way through the body. Waves that are reflected from
deeper structures lose more energy. To compensate for this, the ultrasound machine applies
more gain to deeper echoes. If the deeper waves mainly travel through fluid, in which
minimal energy is lost, the machine “overcompensates”, and the resulting image appears “too
bright”.
Fig. 7 – Enhancement
artifact below the
urinary bladder
(asterisk) containing
hypoechoic fluid (A).
The enhancement
artifact is rendered in
red in B.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
A B
*
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Artifacts
Anisotropy is an angle-generated artifact, which is mainly encountered in musculoskeletal ultrasound.
Anisotropy refers to fibrillar structures such as a tendon or a ligament reflecting the ultrasound waves away
from the transducer. (Fig. 8) The amount of echo is therefore reduced, and the structure seems hypoechoic.
Fig. 8 – A. Schematic drawing illustrating the formation of this angle-generated artifact. B and C. two pictures of the same
tendon taken moments apart. Notice the change of echogenicity from hypoechoic (A) to hyperechoic B). The only difference is
the angle of the transducer relative to the tendon.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
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References
Test Your Knowledge
B C
A
Anisotropy can lead to misinterpreting a tendon as hypoechoic and damaged,
when it is in fact due to anisotropy. Anisotropy can be alleviated by changing
the angle of the transducer relative to the subject.
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
The Doppler Effect
The Doppler effect is used extensively in ultrasound to detect and measure movement within the subject,
especially blood flow within vessels.
The Doppler effect causes a shift in the frequency of sound waves when the emitting object is moving in
relation to the observer. (Fig. 9)
The perceived frequency of the sound increases when the emitter is moving towards the observer, and the
frequency lowers when the emitter is moving away from the observer.
The classic example is that of an ambulance sounding its siren while
passing by a bystander.
Fig. 9 - The bystanders (dots) perceive the siren pitch
differently depending on whether the ambulance
moves towards them or away from them.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
The Doppler Effect
Emitted wave
Reflected wave has an increased
frequency
In medical ultrasound, the frequency of the echo shifts when the reflecting tissue is moving relative to the
transducer (Fig. 10).
The frequency of the echo increases when the reflecting tissue is moving towards the transducer, and the
frequency lowers when the reflecting tissue is moving away from the transducer.
Fig. 10 – The Doppler effect in medical ultrasound. The reflecting tissue here (green dot) is moving
towards the transducer.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
The Doppler Effect
This is an example of using colour Doppler overlay (Fig. 11). This ultrasound system colours objects, in this
case blood, moving towards the transducer (positive Doppler shift) in red, and objects moving away from
the transducer (negative Doppler shift) are coloured in blue.
The colours assigned can differ from machine to machine, so be careful!
Fig. 11 – Splenic vein with colour
Doppler overlay. The flow
velocity (in cm/s) and flow
direction are indicated in the
scale on the left side of the
ultrasound image.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
Negative Doppler shift =>
negative velocity (blue)
Positive Doppler shift =>
positive velocity (red)
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
The Doppler Effect
This is used to answer both qualitative and quantitative questions. Here are some questions that can be
answered with use of the Doppler effect:
Qualitative:
• Is there increased blood flow in the gallbladder wall as a sign of inflammation?
• Is there reduced blood flow in the testis as a sign of possible testicular torsion?
Quantitative:
• What is the flow rate through the patient’s heart valve?
• What is the flow rate through the patient’s carotid artery? Does the rate indicate stenosis?
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Contrast Enhanced Ultrasound (CEUS)
CEUS uses a different contrast agent than CT or MRI.
Different contrast agent formulations exist, but they are all solutions of gas containing microbubbles. The
bubbles diffuse into the tissues in much the same way as other contrast agents, but they are strictly
intravascular opposed to other contrast agents.
Half life in the blood stream is around 5-15 minutes, and side effects are extremely rare.
Common indications for CEUS are:
• Characterization of liver masses (Fig. 12).
• Perioperative visualization of targets in ablation procedures.
• Characterization of masses in other organs.
=> see also e book chapter on contrast agents
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Contrast Enhanced Ultrasound (CEUS)
Fig. 12 – Regular US image (A) showing a slightly hypoechoic and heterogenous liver mass (red
arrow) surrounded by normal liver parenchyma. CEUS (B) in portal venous phase reveals the mass
(green arrow) to have distinct washout of contrast, strongly suggesting malignancy – this turned
out to be a metastasis. Notice the hypoechoic area above the liver (white arrow in A) – this is
ascites.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
A B
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Contrast Enhanced Ultrasound (CEUS)
CEUS is generally considered very safe.
Contraindications vary for different formulations. Below are a summarization of contraindications that need
to be considered when performing CEUS:
• Hypersensitivity to the active substances.
• Known right-to-left cardiac shunt.
• Severe pulmonary hypertension or uncontrolled systemic hypertension.
• Acute respiratory distress syndrome.
• Known egg allergy (only some formulations).
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Strengths and Limitations
Strengths and limitations of ultrasound vary greatly with different applications.
Below is an outline of general strengths and limitations of ultrasound as opposed to other imaging
modalities, such as CT and MRI, that one needs to consider when choosing between modalities.
=> see for specific applications also e book chapters on bile ducts, small bowel, musculoskeletal, cardiac
and paediatric imaging
Strengths:
• Low cost
• High availability
• High portability
• Safe and non-invasive
• Fast
• Dynamic
Limitations:
• Highly operator dependant
• Highly patient dependant
• Difficult to reproduce
• Poor penetration in air and bone
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
Take-Home Messages
• Ultrasound waves are sound waves with a high frequency.
• We analyse the echoes to gain information about the subject matter and depict them as images on a
screen.
• Different transducers are used for different applications
• Ultrasound artifacts are important to be aware of, as they may influence your diagnosis.
• The Doppler effect is used extensively to visualize movement and in particular blood flow.
• CEUS is generally a safe way to characterize liver lesions and has also other applications.
• Ultrasound has strengths and limitations that one needs to consider before performing an
examination.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
References
1. Rumack, C.M.; Wilson, S.R.; Charboneau, J.W. Diagnostic ultrasound. 2005, 3rd edition
2. Postema, M.; Kotopoulis, S.; Jenderka, K.-V. Physical Principles of Medical Ultrasound. EFSUMB Courseb.
Ultrasound 2020, 1–23.
3. WFUMB ULTRASOUND BOOK Available online: http://wfumb.info/wfumb-ultrasound-book/additional-
pages/html5_output/index.html (accessed on Aug 14, 2022).
4. Nolsøe, C.P
.; Lorentzen, T. International guidelines for contrast-enhanced ultrasonography: ultrasound
imaging in the new millennium. Ultrasonography 2016, 35, 89.
5. Appis, A.W.; Tracy, M.J.; Feinstein, S.B. Update on the safety and efficacy of commercial ultrasound contrast
agents in cardiac applications. Echo Res. Pract. 2015, 2, R55.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
1 – Medical ultrasound typically uses which frequency range?
• The kHz range
• The MHz range
• The Hz range
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
1 – Medical ultrasound typically uses which frequency range?
• The kHz range
 The MHz range
• The Hz range
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
2 – Which of the following is not a way that ultrasound waves interact with the tissues within the
body?
• Reflection
• Polarisation
• Refraction
• Scattering
• Absorption
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
2 – Which of the following is not a way that ultrasound waves interact with the tissues within the
body?
• Reflection
 Polarisation
• Refraction
• Scattering
• Absorption
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
3 – Objects that appear bright on the ultrasound screen are referred to as what?
• Hypoechoic
• Isoechoic
• Hyperechoic
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
3 – Objects that appear bright on the ultrasound screen are referred to as what?
• Hypoechoic
• Isoechoic
 Hyperechoic
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
4 – Which of the follow common types of transducer yields images with a high resolution?
• Curved probe, 1-5 MHz
• Phased array transducer, 1-5 MHz
• Linear transducer, 3-12 MHz
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
4 – Which of the follow common types of transducer yields images with a high resolution?
• Curved probe, 1-5 MHz
• Phased array transducer, 1-5 MHz
 Linear transducer, 3-12 MHz
Test Your Knowledge
Linear, 3-12 MHz
Advantages: High resolution.
Disadvantages: Poor penetration.
Musculoskeletal, superficial
structures.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
5 – Which common ultrasound artifact is seen here?
• Acoustic shadowing
• Enhancement
• Anisotropy
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
5 – Which common ultrasound artifact is seen here?
 Acoustic shadowing
• Enhancement
• Anisotropy
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
6 – In which direction does the blood flow through this vein?
• Left to right
• Right to left
(note: colouring conventions used are as
explained on slide no. 19.)
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
6 – In which direction does the blood flow through this vein?
• Left to right
 Right to left
(note: colouring conventions used are as
explained on slide no. 19)
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
7 – Which of the following is not a contraindication for CEUS?
• Known right-to-left cardiac shunt.
• Severe pulmonary hypertension or uncontrolled systemic hypertension.
• Acute respiratory distress syndrome.
• Hepatic tumour of unknown type
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
7 – Which of the following is not a contraindication for CEUS?
• Known right-to-left cardiac shunt.
• Severe pulmonary hypertension or uncontrolled systemic hypertension.
• Acute respiratory distress syndrome.
 Hepatic tumour of unknown type
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
8 – Name three general strengths and three general limitations of medical ultrasound.
Test Your Knowledge
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
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eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
8 – Name three general strengths and three general limitations of medical ultrasound.
Test Your Knowledge
Strengths:
• Low cost
• High availability
• High portability
• Safe and non-invasive
• Fast
• Dynamic
Limitations:
• Highly operator dependant
• Highly patient dependant
• Difficult to reproduce
• Poor penetration in air and bone
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge
eBook for Undergraduate Education in Radiology
Chapter:
Ultrasound
Chapter Outline
All material used (including intellectual property and illustration elements) either
originates from the authors, the authors were entitled to use the material by applicable
law or have obtained a transferable license from the copyright holder.
Ultrasound Basics
Signal to Image
Artifacts
The Doppler Effect
Contrast Enhanced
Ultrasound
Strengths and
Limitations
Take-Home Messages
References
Test Your Knowledge

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ESR eBook for Undergraduate Education in Radiology – 02b Ultrasound.pdf

  • 1. eBook for Undergraduate Education in Radiology Chapter Outline CHAPTER: Ultrasound
  • 2. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Preface Undergraduate teaching of radiology in Europe is provided according to national schemes and may vary considerably from one academic institution to another. Sometimes, the field of radiology is considered as a “cross- cutting discipline” or taught within the context of other clinical disciplines, e.g., internal medicine or surgery. This e-book has been created in order to serve medical students and academic teachers throughout Europe to understand and teach radiology as a whole coherent discipline, respectively. Its contents are based on the Undergraduate Level of the ESR European Training Curriculum for Radiology and summarize the so-called core elements that may be considered as the basics that every medical student should be familiar with. Although specific radiologic diagnostic skills for image interpretation cannot be acquired by all students and rather belong to the learning objectives of the Postgraduate Levels of the ESR Training Curricula, the present e-book also contains some further insights related to modern imaging in the form of examples of key pathologies, as seen by the different imaging modalities. These are intended to give the interested undergraduate student an understanding of modern radiology, reflecting its multidisciplinary character as an organ-based specialty. We would like to extend our special thanks to the authors and members of the ESR Education Committee who have contributed to this eBook, to Carlo Catalano, who initiated this project, and to the ESR Office, in particular Bettina Leimberger and Danijel Lepir, for all their support in realising this project. We hope that this e-book may fulfil its purpose as a useful tool for undergraduate academic radiology teaching. Minerva Becker Vicky Goh ESR Education Committee Chair ESR Undergraduate Education Subcommittee Chair Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 3. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Copyright and Terms of Use This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. You are free to: • Share – copy and redistribute the material in any medium or format Under the following terms: • Attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. • NonCommercial – You may not use the material for commercial purposes. • NoDerivatives – If you remix, transform, or build upon the material, you may not distribute the modified material. How to cite this work: European Society of Radiology, Jonathan Cohen, Caroline Ewertsen (2022) eBook for Undergraduate Education in Radiology: Ultrasound. DOI 10.26044/esr-undergraduate-ebook-08 Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 4. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Hyperlinks Core Knowledge Further Knowledge Compare Questions References Attention Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 5. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline eBook for Undergraduate Education in Radiology BasedontheESRCurriculumforUndergraduateRadiologicalEducation Chapter: Ultrasound Authors Affiliation Jonathan Cohen Caroline Ewertsen Department of Radiology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge mailjonathancohen@gmail.com caroline.ewertsen@dadlnet.dk
  • 6. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Chapter Outline • Ultrasound Basics  Physics • Signal to Image  Equipment  Enhancing the Image • Artifacts  Acoustic Shadowing  Enhancement  Anisotropy • The Doppler Effect  Basic Physics  Use in Medical Ultrasound • Contrast Enhanced Ultrasound  Indications and Contraindications • Strengths and Limitations • Take-Home Messages • References • Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 7. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Sonography is a non-invasive painless procedure, which uses ultrasound waves to produce images of organs, blood vessels or soft tissues for medical analysis. The terms sonography and ultrasound are often used interchangeably. A sonogram is an image generated by ultrasound. Ultrasound waves have frequencies higher than the upper limit of human hearing. In medical ultrasound, frequencies typically fall in the 1 to 20 MHz range, while the upper limit of human hearing is around 20 kHz. The basic ultrasound principle (Fig. 1): • An ultrasound transducer emits an ultrasound signal. • The transducer listens for the echo generated by the structures that the wave encounters. • The echo is turned into an image based on characteristics of the echo, such as timing, amplitude and frequency. Ultrasound Basics Emitted wave Reflected wave Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge Fig. 1 – Schematic representation of the basic ultrasound (sonography or ultrasonography) principle.
  • 8. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Ultrasound interacts with tissues in different ways: • Reflection – waves are reflected back to the transducer. • Absorption – waves are absorbed by the tissue and the energy is converted to heat. • Scattering – waves are reflected in multiple different directions. • Refraction – the direction of waves is changed Each type of tissue has a particular impedance – a resistance to the propagation of sound which depends on the tissue density and the speed of sound in the tissue. The amount of generated reflection depends on differences in impedance between tissues. As an example, if the ultrasound wave travels from fat (low impedance) to bone (high impedance) a large difference in impedance is encountered, and a powerful echo will be generated. Ultrasound Basics Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 9. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Ultrasound Basics Structures that elicit a powerful echo appear bright on our screen – we call them hyperechoic (Fig. 2). Structures that elicit a weak echo appear dark on our screen – we call them hypoechoic (Fig. 3). Structures that elicit an echo similar to their surrounding structures are called isoechoic. Fig. 2 – Cortical bone is strongly hyperechoic (green arrow) and casts an acoustic shadow (more on that later). Fig. 3 – Urinary bladder filled with hypoechoic fluid (red arrow). Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 10. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Signal to Image The ultrasound equipment generates an electrical signal (Fig. 4) which is sent through a cable to the ultrasound transducer (sometimes called an ultrasound probe). In the transducer, an array of piezoelectric crystals translate the signal to sound waves, which propagate from the probe outwards (Fig. 4). Piezoelectric crystals are crystals which have the ability to generate an electric charge when mechanical pressure is applied (e.g., quartz). The same crystals convert the returning ultrasound echo into an electrical signal, which the ultrasound system then converts to an image. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge Fig. 4 – Schematic representation of the process by which an ultrasound image (sonogram or ultrasonogram) is generated.
  • 11. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Signal to Image Different ultrasound transducers (Fig. 5) have different strengths and limitations, and therefore different applications. Below is an overview of the most common transducer types and their typical applications. Curved, 1-5 MHz Advantages: Good penetration, wide field of view. Disadvantages: Low resolution. Abdominal, deep structures. Linear, 3-12 MHz Advantages: High resolution. Disadvantages: Poor penetration. Musculoskeletal, superficial structures, neck. Phased array, 1-5 MHz Advantages: Wide field of view with small transducer surface Disadvantages: Low resolution. Echocardiography, intercostal views. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge Fig. 5 – Advantages, disadvantages and main applications of different types of ultrasound transducers
  • 12. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Signal to Image Modern ultrasound systems continually and automatically optimize the image while you scan. Some parameters can be adjusted by the user to further optimize the image. • Gain: high gain increases the overall brightness of the image, but also increases noise. • Frequency: high frequency means better image quality, but poorer penetration. Most transducers have a set centre frequency, around which the frequency can be adjusted slightly. • Depth: larger depth gives better overview, but details appear less visible. • Focus: improves the appearance of the ultrasound image at the depth at which the focus is set. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 13. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Artifacts Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge Interactions between the ultrasound equipment and the body often cause artifacts. In ultrasound, some artifacts can be used to gain information about what you are scanning. The following slides illustrate some of the most common artifacts encountered: acoustic shadowing, enhancement and anisotropy. Knowledge of artifacts is imperative when performing ultrasound, as wrong interpretations of artifacts can lead to misdiagnosis!
  • 14. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Artifacts Acoustic shadowing (Fig. 6) corresponds to low signal behind structures that strongly absorb or reflect ultrasound waves. Fig. 6 – Gall bladder containing multiple gall stones which display acoustic shadowing (A). In image B, acoustic shadowing is rendered by green overlay. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge A B
  • 15. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Artifacts Enhancement (Fig. 7) corresponds to increased signal below structures that transmit sound well (e.g. fluid). Ultrasound waves lose energy on their way through the body. Waves that are reflected from deeper structures lose more energy. To compensate for this, the ultrasound machine applies more gain to deeper echoes. If the deeper waves mainly travel through fluid, in which minimal energy is lost, the machine “overcompensates”, and the resulting image appears “too bright”. Fig. 7 – Enhancement artifact below the urinary bladder (asterisk) containing hypoechoic fluid (A). The enhancement artifact is rendered in red in B. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge A B *
  • 16. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Artifacts Anisotropy is an angle-generated artifact, which is mainly encountered in musculoskeletal ultrasound. Anisotropy refers to fibrillar structures such as a tendon or a ligament reflecting the ultrasound waves away from the transducer. (Fig. 8) The amount of echo is therefore reduced, and the structure seems hypoechoic. Fig. 8 – A. Schematic drawing illustrating the formation of this angle-generated artifact. B and C. two pictures of the same tendon taken moments apart. Notice the change of echogenicity from hypoechoic (A) to hyperechoic B). The only difference is the angle of the transducer relative to the tendon. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge B C A Anisotropy can lead to misinterpreting a tendon as hypoechoic and damaged, when it is in fact due to anisotropy. Anisotropy can be alleviated by changing the angle of the transducer relative to the subject.
  • 17. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline The Doppler Effect The Doppler effect is used extensively in ultrasound to detect and measure movement within the subject, especially blood flow within vessels. The Doppler effect causes a shift in the frequency of sound waves when the emitting object is moving in relation to the observer. (Fig. 9) The perceived frequency of the sound increases when the emitter is moving towards the observer, and the frequency lowers when the emitter is moving away from the observer. The classic example is that of an ambulance sounding its siren while passing by a bystander. Fig. 9 - The bystanders (dots) perceive the siren pitch differently depending on whether the ambulance moves towards them or away from them. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 18. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline The Doppler Effect Emitted wave Reflected wave has an increased frequency In medical ultrasound, the frequency of the echo shifts when the reflecting tissue is moving relative to the transducer (Fig. 10). The frequency of the echo increases when the reflecting tissue is moving towards the transducer, and the frequency lowers when the reflecting tissue is moving away from the transducer. Fig. 10 – The Doppler effect in medical ultrasound. The reflecting tissue here (green dot) is moving towards the transducer. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 19. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline The Doppler Effect This is an example of using colour Doppler overlay (Fig. 11). This ultrasound system colours objects, in this case blood, moving towards the transducer (positive Doppler shift) in red, and objects moving away from the transducer (negative Doppler shift) are coloured in blue. The colours assigned can differ from machine to machine, so be careful! Fig. 11 – Splenic vein with colour Doppler overlay. The flow velocity (in cm/s) and flow direction are indicated in the scale on the left side of the ultrasound image. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge Negative Doppler shift => negative velocity (blue) Positive Doppler shift => positive velocity (red)
  • 20. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline The Doppler Effect This is used to answer both qualitative and quantitative questions. Here are some questions that can be answered with use of the Doppler effect: Qualitative: • Is there increased blood flow in the gallbladder wall as a sign of inflammation? • Is there reduced blood flow in the testis as a sign of possible testicular torsion? Quantitative: • What is the flow rate through the patient’s heart valve? • What is the flow rate through the patient’s carotid artery? Does the rate indicate stenosis? Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 21. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Contrast Enhanced Ultrasound (CEUS) CEUS uses a different contrast agent than CT or MRI. Different contrast agent formulations exist, but they are all solutions of gas containing microbubbles. The bubbles diffuse into the tissues in much the same way as other contrast agents, but they are strictly intravascular opposed to other contrast agents. Half life in the blood stream is around 5-15 minutes, and side effects are extremely rare. Common indications for CEUS are: • Characterization of liver masses (Fig. 12). • Perioperative visualization of targets in ablation procedures. • Characterization of masses in other organs. => see also e book chapter on contrast agents Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 22. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Contrast Enhanced Ultrasound (CEUS) Fig. 12 – Regular US image (A) showing a slightly hypoechoic and heterogenous liver mass (red arrow) surrounded by normal liver parenchyma. CEUS (B) in portal venous phase reveals the mass (green arrow) to have distinct washout of contrast, strongly suggesting malignancy – this turned out to be a metastasis. Notice the hypoechoic area above the liver (white arrow in A) – this is ascites. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge A B
  • 23. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Contrast Enhanced Ultrasound (CEUS) CEUS is generally considered very safe. Contraindications vary for different formulations. Below are a summarization of contraindications that need to be considered when performing CEUS: • Hypersensitivity to the active substances. • Known right-to-left cardiac shunt. • Severe pulmonary hypertension or uncontrolled systemic hypertension. • Acute respiratory distress syndrome. • Known egg allergy (only some formulations). Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 24. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Strengths and Limitations Strengths and limitations of ultrasound vary greatly with different applications. Below is an outline of general strengths and limitations of ultrasound as opposed to other imaging modalities, such as CT and MRI, that one needs to consider when choosing between modalities. => see for specific applications also e book chapters on bile ducts, small bowel, musculoskeletal, cardiac and paediatric imaging Strengths: • Low cost • High availability • High portability • Safe and non-invasive • Fast • Dynamic Limitations: • Highly operator dependant • Highly patient dependant • Difficult to reproduce • Poor penetration in air and bone Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 25. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline Take-Home Messages • Ultrasound waves are sound waves with a high frequency. • We analyse the echoes to gain information about the subject matter and depict them as images on a screen. • Different transducers are used for different applications • Ultrasound artifacts are important to be aware of, as they may influence your diagnosis. • The Doppler effect is used extensively to visualize movement and in particular blood flow. • CEUS is generally a safe way to characterize liver lesions and has also other applications. • Ultrasound has strengths and limitations that one needs to consider before performing an examination. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 26. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline References 1. Rumack, C.M.; Wilson, S.R.; Charboneau, J.W. Diagnostic ultrasound. 2005, 3rd edition 2. Postema, M.; Kotopoulis, S.; Jenderka, K.-V. Physical Principles of Medical Ultrasound. EFSUMB Courseb. Ultrasound 2020, 1–23. 3. WFUMB ULTRASOUND BOOK Available online: http://wfumb.info/wfumb-ultrasound-book/additional- pages/html5_output/index.html (accessed on Aug 14, 2022). 4. Nolsøe, C.P .; Lorentzen, T. International guidelines for contrast-enhanced ultrasonography: ultrasound imaging in the new millennium. Ultrasonography 2016, 35, 89. 5. Appis, A.W.; Tracy, M.J.; Feinstein, S.B. Update on the safety and efficacy of commercial ultrasound contrast agents in cardiac applications. Echo Res. Pract. 2015, 2, R55. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 27. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 1 – Medical ultrasound typically uses which frequency range? • The kHz range • The MHz range • The Hz range Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 28. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 1 – Medical ultrasound typically uses which frequency range? • The kHz range  The MHz range • The Hz range Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 29. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 2 – Which of the following is not a way that ultrasound waves interact with the tissues within the body? • Reflection • Polarisation • Refraction • Scattering • Absorption Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 30. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 2 – Which of the following is not a way that ultrasound waves interact with the tissues within the body? • Reflection  Polarisation • Refraction • Scattering • Absorption Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 31. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 3 – Objects that appear bright on the ultrasound screen are referred to as what? • Hypoechoic • Isoechoic • Hyperechoic Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 32. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 3 – Objects that appear bright on the ultrasound screen are referred to as what? • Hypoechoic • Isoechoic  Hyperechoic Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 33. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 4 – Which of the follow common types of transducer yields images with a high resolution? • Curved probe, 1-5 MHz • Phased array transducer, 1-5 MHz • Linear transducer, 3-12 MHz Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 34. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 4 – Which of the follow common types of transducer yields images with a high resolution? • Curved probe, 1-5 MHz • Phased array transducer, 1-5 MHz  Linear transducer, 3-12 MHz Test Your Knowledge Linear, 3-12 MHz Advantages: High resolution. Disadvantages: Poor penetration. Musculoskeletal, superficial structures. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 35. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 5 – Which common ultrasound artifact is seen here? • Acoustic shadowing • Enhancement • Anisotropy Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 36. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 5 – Which common ultrasound artifact is seen here?  Acoustic shadowing • Enhancement • Anisotropy Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 37. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 6 – In which direction does the blood flow through this vein? • Left to right • Right to left (note: colouring conventions used are as explained on slide no. 19.) Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 38. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 6 – In which direction does the blood flow through this vein? • Left to right  Right to left (note: colouring conventions used are as explained on slide no. 19) Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 39. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 7 – Which of the following is not a contraindication for CEUS? • Known right-to-left cardiac shunt. • Severe pulmonary hypertension or uncontrolled systemic hypertension. • Acute respiratory distress syndrome. • Hepatic tumour of unknown type Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 40. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 7 – Which of the following is not a contraindication for CEUS? • Known right-to-left cardiac shunt. • Severe pulmonary hypertension or uncontrolled systemic hypertension. • Acute respiratory distress syndrome.  Hepatic tumour of unknown type Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 41. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 8 – Name three general strengths and three general limitations of medical ultrasound. Test Your Knowledge Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 42. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline 8 – Name three general strengths and three general limitations of medical ultrasound. Test Your Knowledge Strengths: • Low cost • High availability • High portability • Safe and non-invasive • Fast • Dynamic Limitations: • Highly operator dependant • Highly patient dependant • Difficult to reproduce • Poor penetration in air and bone Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge
  • 43. eBook for Undergraduate Education in Radiology Chapter: Ultrasound Chapter Outline All material used (including intellectual property and illustration elements) either originates from the authors, the authors were entitled to use the material by applicable law or have obtained a transferable license from the copyright holder. Ultrasound Basics Signal to Image Artifacts The Doppler Effect Contrast Enhanced Ultrasound Strengths and Limitations Take-Home Messages References Test Your Knowledge