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Quality of care after first acute myocardial
                 infarction (AMI)

a comparison of native Danes and immigrants from Turkey,
           Pakistan and the former Yugoslavia



           Nana Folmann Hempler, PhD, Post.doc

                     University of Copenhagen
                     Centre for Healthy Aging
              Section for Health Services Research
                    Department of Public Health
Research questions


Do immigrants receive adequate medical
treatment with beta-blockers and statins after
acute myocardial infarction, compared with
native Danes?

Are potential differences partially explained
by social inequalities?
Data on cardiovascular disease (CVD) among
Non-Western immigrants in Denmark


Increased number of CVD-specific hospital contacts
Folmann and Jørgensen 2006, Ingerslev 2000


Increased diabetes
Kristensen et al. 2007


CVD risk factors increased
Singhammer 2008


Increased incidence of CVD and AMI among Turks
and Pakistanis
Hempler NF et al. 2011
Data on CVD



Lack of studies regarding:

• Immigrants’ access to healthcare services

• Whether immigrants with CVD receive adequate treatment
Background




Immigrants and descendants comprise 10% of the population
Statistics Denmark 2010



Two-thirds originate from a non-Western country
Background
Methods

Capital Region of Denmark or Central Denmark
Region (n=3,107,901)

Study population:
• Native Danes
• Turks, Pakistanis, former Yugoslavians
  (not including refugees from the civil war)

Non-Western groups with:
• The longest duration of stay in Denmark
• The highest average age
Definitions


Native Danes were used as the reference group

However, not a gold standard
Social inequalities




                      Health
  Differences in
  socioeconomic       Access to healthcare services
   status (SES)
                      Quality of care
Socioeconomic status (SES)

Lower SES among non-Western immigrants compared
with native Danes

• Income

• Education

• Employment

• Housing conditions
Data Sources

                         The Danish National
                           Patient Registry
 The Integrated
                                                The Danish Registry
 Database for Labour
                             The Central        of Medical Product
 Market Research
                             Population         Statistics
                             Registry
The Danish                                        The Registry of
Demographic                                       Causes of Death
Registry


                            Admissions
                       Redeemed prescriptions
                        Employment, income
                          Country of birth
                            Migrations
                              Deaths
Country of Birth

Immigrant:
Born in a foreign country to parents without
Danish citizenship also born in a foreign country

Descendant:
Born in Denmark to parents born in a foreign
country without Danish citizenship

Native Dane:
Individual with at least one parent, who is a
Danish citizen born in Denmark
Design



Inclusion criteria:
Residence in
Denmark 1997-2000



1997         Baseline                 2005
             (2001)




                        Initiation
                        Persistence
Facts


Guidelines recommend treatment with statins and
beta-blockers after AMI


Prescription drugs require co-payment
Methods


No previous history of AMI

Discharged alive after first AMI

22,335 individuals (322 immigrants)

Covariates: age, sex, employment, income

Outcomes: Statins and beta-blockers
Initiation: within 14 days after discharge
Persistence: no refill 90 days after the defined daily dose expired
Results – initiation (OR)




Ref.: native Danes
Results – persistence (HR)




 Ref.: native Danes
Conclusions

Pakistanis and Turks were less likely to receive
adequate treatment with beta-blockers after AMI

Poorer persistence with statins and, in particular, beta-
blockers

A trend of better initiation among immigrant groups

No strong effect of SES was observed
Interpretation of results

Insufficient indicators of SES

Communication obstacles between provider and patient

Lack of social support

Differences in perceived need

Use of cross border healthcare services
Discussion
Strengths:
Follow-up design
Measurement of SES before measurement of outcome
Registry-based data of high quality regarding the outcomes
Country of birth categories

Limitations:
Small sample size of immigrants groups (type II errors)
Cases before 1997 could not be identified
Misclassification of outcome
Broad categories (SES indicators)
Poor validity of education
Country of birth does not take ethnic identity, culture and
language into account
Further reading


Hempler NF, Diderichsen F, Larsen FB, Ladelund S,
Jorgensen T.
Do immigrants from Turkey, Pakistan and Yugoslavia
receive adequate medical treatment with beta-
blockers and statins after acute myocardial infarction
compared with Danish-born residents? A register-
based follow-up study.
Eur J Clin Pharmacol 2010; 66(7): 735-42.
Thank you for your attention




 The Copenhagen Center for Healthy Aging
 is supported by the Danish foundation

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Nfhk2011 nana folmann hempler_parallel25

  • 1. Quality of care after first acute myocardial infarction (AMI) a comparison of native Danes and immigrants from Turkey, Pakistan and the former Yugoslavia Nana Folmann Hempler, PhD, Post.doc University of Copenhagen Centre for Healthy Aging Section for Health Services Research Department of Public Health
  • 2. Research questions Do immigrants receive adequate medical treatment with beta-blockers and statins after acute myocardial infarction, compared with native Danes? Are potential differences partially explained by social inequalities?
  • 3. Data on cardiovascular disease (CVD) among Non-Western immigrants in Denmark Increased number of CVD-specific hospital contacts Folmann and Jørgensen 2006, Ingerslev 2000 Increased diabetes Kristensen et al. 2007 CVD risk factors increased Singhammer 2008 Increased incidence of CVD and AMI among Turks and Pakistanis Hempler NF et al. 2011
  • 4. Data on CVD Lack of studies regarding: • Immigrants’ access to healthcare services • Whether immigrants with CVD receive adequate treatment
  • 5. Background Immigrants and descendants comprise 10% of the population Statistics Denmark 2010 Two-thirds originate from a non-Western country
  • 7. Methods Capital Region of Denmark or Central Denmark Region (n=3,107,901) Study population: • Native Danes • Turks, Pakistanis, former Yugoslavians (not including refugees from the civil war) Non-Western groups with: • The longest duration of stay in Denmark • The highest average age
  • 8. Definitions Native Danes were used as the reference group However, not a gold standard
  • 9. Social inequalities Health Differences in socioeconomic Access to healthcare services status (SES) Quality of care
  • 10. Socioeconomic status (SES) Lower SES among non-Western immigrants compared with native Danes • Income • Education • Employment • Housing conditions
  • 11. Data Sources The Danish National Patient Registry The Integrated The Danish Registry Database for Labour The Central of Medical Product Market Research Population Statistics Registry The Danish The Registry of Demographic Causes of Death Registry Admissions Redeemed prescriptions Employment, income Country of birth Migrations Deaths
  • 12. Country of Birth Immigrant: Born in a foreign country to parents without Danish citizenship also born in a foreign country Descendant: Born in Denmark to parents born in a foreign country without Danish citizenship Native Dane: Individual with at least one parent, who is a Danish citizen born in Denmark
  • 13. Design Inclusion criteria: Residence in Denmark 1997-2000 1997 Baseline 2005 (2001) Initiation Persistence
  • 14. Facts Guidelines recommend treatment with statins and beta-blockers after AMI Prescription drugs require co-payment
  • 15. Methods No previous history of AMI Discharged alive after first AMI 22,335 individuals (322 immigrants) Covariates: age, sex, employment, income Outcomes: Statins and beta-blockers Initiation: within 14 days after discharge Persistence: no refill 90 days after the defined daily dose expired
  • 16. Results – initiation (OR) Ref.: native Danes
  • 17. Results – persistence (HR) Ref.: native Danes
  • 18. Conclusions Pakistanis and Turks were less likely to receive adequate treatment with beta-blockers after AMI Poorer persistence with statins and, in particular, beta- blockers A trend of better initiation among immigrant groups No strong effect of SES was observed
  • 19. Interpretation of results Insufficient indicators of SES Communication obstacles between provider and patient Lack of social support Differences in perceived need Use of cross border healthcare services
  • 20. Discussion Strengths: Follow-up design Measurement of SES before measurement of outcome Registry-based data of high quality regarding the outcomes Country of birth categories Limitations: Small sample size of immigrants groups (type II errors) Cases before 1997 could not be identified Misclassification of outcome Broad categories (SES indicators) Poor validity of education Country of birth does not take ethnic identity, culture and language into account
  • 21. Further reading Hempler NF, Diderichsen F, Larsen FB, Ladelund S, Jorgensen T. Do immigrants from Turkey, Pakistan and Yugoslavia receive adequate medical treatment with beta- blockers and statins after acute myocardial infarction compared with Danish-born residents? A register- based follow-up study. Eur J Clin Pharmacol 2010; 66(7): 735-42.
  • 22. Thank you for your attention The Copenhagen Center for Healthy Aging is supported by the Danish foundation