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Genomics-based
Healthcare Prevention
Well-being is coded in your DNA
 @NOAHConference
 @noah_conference
 @noah-conference
 @NOAHConference
FOLLOW USONSOCIAL
Do we have a Disease System and no Health System?
Health Unhealthy
2
• The health system only takes effect
when people become ill.
• This leads to a high burden on the
health system and society.
• Furthermore, there are lower
chances of achieving good results
for patients.
• Real-time screening of the health status
with sensors and biomarkers allows
early detection of disease formation
• Optimal adaptation of lifestyle based on
genetic and microbial background
Today‘s Problem
The digital and genomic revolution will change healthy living in
an unprecedented way.
3Confidential
Our mission
To empower people to live healthier lives by understanding their human &
microbial DNA and providing them with individualized health and wellness.
4
The 2nd Genome - The Microbiom?
5
What is microbiota?
Highly complex ecological community of commensal, symbiotic & pathogenic microorganisms.
100 trillion microbial cells living in and on parts of the human body like gut, skin, mouth, nose or genitals.
Outnumbering the human cells 10-fold and the human genome 150-fold.
Carries out important work the body cannot do itself and has a critical influence on health & wellbeing.
Consisting of bacteria, fungi, viruses and archaea.
What Is Microbiota Good For?
INDISPENSABLE FOR
HEALTH AND WELLBEING
REGULATES
mood, health and wellbeing
INFLUENCES
body weight and the
calories you harvest
FACILITATES
digestion & nutrient
uptake
TEACHES
the immune system
PROTECTS
against harmful
microorganisms
SYNTHESIZES
vitamins, including B12, K
and Folate
B12
K
C19H19N7O6
6
INTEST.pro: our first consumer product
INTEST.pro is an easy-to-use collection kit
that can be used comfortably and
privately at home.
Gut flora analysis
Information about one‘s own
microorganisms, along with personalized
recommendations on how to improve
one‘s own microbiota.
Detailed report with recommendations
7
How Does It Work?
1 2 3 4 5 6
Customer
buys
INTEST.pro
Customer
takes a
sample
Customer sends
sample back to
BIOMES
Microbiome
extraction &
NGS analysis
Profile exploration,
including
personalized
recommendations
for the customer
Data processing
& result
matching
8
What’s in Each Customer’s Report?
9
Report features:
Immune system and wellbeing
Vitamin synthesis
Calorie harvest
Gut microbiome balance
Food intolerances
Digestion & nutrition uptake
Intestinal mucosa
Personalized nutrition plans
Personalized probiotic supplements
The Benefits of our Process
INTEST.pro is a quantum leap compared to
classical intestinal flora analysis.
Measure and quantify the
totality of microbes.
2.5B
3.2B
unprecedented depth of analysis made possible
with DNA sequencing
with minimal sample amount
unique, curated & proprietary knowledge database
(>6,000 studies)
personalized report based on the power of
community
individualized recommendations and personalized
nutrition plans
10
Where we help
PERFORMAN
CE & FITNESS
Fitness/Nutrition
Metabolic/Health
1
DIET &
NUTRITION
WEIGHT LOSS
& OBESITY
DIGESTION
PROBLEMS
IRRITABLE
BOWEL
SYNDROM
What’s wrong & why? How can you get better?
2 3 4 5
11
Wellbeing Spectrum
Huge Market Opportunity
by example of the e-Health market and Irritable bowel syndrome (IBS)
320
280
240
200
160
120
80
40
0
$ Billions
CAGR = 15.8%
2014 2016 2020 2021 2022
Global e-Health market will reach
€264 billion by 2022
e-Health: A hot global megatrend
Market potential given by IBS in Germany
15 million people in
Germany suffer from IBS
€ 1.94 billion market potential for
Germany
Additional huge market
potential through personalized
probiotics
Global Market volume of e-Health
12
Up-sale
Importance:
Additional business
Market potential:
Large
Duration:
Short-term
Informati
on
Knowledge
Data
Data & Knowledge
Importance:
Additional business
Market potential:
Very large
Duration:
Long-term
Business Model
Importance:
CORE BUSINESS
Market potential:
Very large
Duration:
Short-term
DNA Analyses
13
• Probiotic
Supplements
• Nutrition plans
• Lead provision
Fast Revenue Growth
14
• Fast growth by market occupation &
product diversification
• Online CAC at SEA, Facebook ~40 €
• Product sale after analytic ~35%
• Low COGS down to 10 € per analytic
(currently 20 €)
• Sales start in summer 2018 with > 250
k€ revenue
• Till June >350 k€ revenue in 2019
(>5.200 tests and >2.500 probiotics)
• 1.3 Mio. € revenue in 2019 with offline
sale deals and internationalization
(ENG, FR, ESP) -2.000.000 €
-1.500.000 €
-1.000.000 €
-500.000 €
0 €
500.000 €
1.000.000 €
1.500.000 €
2.000.000 €
2.500.000 €
3.000.000 €
3.500.000 €
- €
2.000.000 €
4.000.000 €
6.000.000 €
8.000.000 €
10.000.000 €
12.000.000 €
14.000.000 €
16.000.000 €
18.000.000 €
2018 2019 2020 2021 2022 2023
Revenue COGS Payroll Other expenses EBIT
Investment Ask
Product diversification
Internationalization –
Europe and Latin America
Marketing & sales activities
R&D and user interface
improvement
Investments already received:
Family & Friends
75k€ Oct 2016
EXIST sponsorship
160k€ Jun 2017
Seed round
600k€ Feb 2018
Funding amount
Up to 2 Mio. EUR by convertible loan (pre-A)
Up to 5 Mio. EUR for series A in Q3 2020
Up to 4 Mio. EUR by public promotion
programs (ProFIT)
Budget
allocation
Human resources
15
High Professional Team
Experienced
management team
Experienced
operational team
Dr. Paul Hammer
CEO & Founder
Andrej Wackerow
CCO & Co-Founder
Carsten Krumbiegel
CTO & Co-Founder
Christin Günther
CMO & Co-Founder
Dr. Tewodros Debebe Aklilu
Head of Science
Philipp Franke
Head of Laboratory
Jonas Dierenbach
Head of IT & Co-Founder
16
We are supported by
CONTACT
info@BIOMES.world
www.BIOMES.world
+49 163 474 15 31
Dr. Paul Hammer
We are awarded by
Alibaba Create
Cloud Contest
Jerusalem
Competition
Pitch Marathon

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BIOMES - NOAH19 Berlin

  • 2.  @NOAHConference  @noah_conference  @noah-conference  @NOAHConference FOLLOW USONSOCIAL
  • 3. Do we have a Disease System and no Health System? Health Unhealthy 2 • The health system only takes effect when people become ill. • This leads to a high burden on the health system and society. • Furthermore, there are lower chances of achieving good results for patients. • Real-time screening of the health status with sensors and biomarkers allows early detection of disease formation • Optimal adaptation of lifestyle based on genetic and microbial background Today‘s Problem
  • 4. The digital and genomic revolution will change healthy living in an unprecedented way. 3Confidential
  • 5. Our mission To empower people to live healthier lives by understanding their human & microbial DNA and providing them with individualized health and wellness. 4
  • 6. The 2nd Genome - The Microbiom? 5 What is microbiota? Highly complex ecological community of commensal, symbiotic & pathogenic microorganisms. 100 trillion microbial cells living in and on parts of the human body like gut, skin, mouth, nose or genitals. Outnumbering the human cells 10-fold and the human genome 150-fold. Carries out important work the body cannot do itself and has a critical influence on health & wellbeing. Consisting of bacteria, fungi, viruses and archaea.
  • 7. What Is Microbiota Good For? INDISPENSABLE FOR HEALTH AND WELLBEING REGULATES mood, health and wellbeing INFLUENCES body weight and the calories you harvest FACILITATES digestion & nutrient uptake TEACHES the immune system PROTECTS against harmful microorganisms SYNTHESIZES vitamins, including B12, K and Folate B12 K C19H19N7O6 6
  • 8. INTEST.pro: our first consumer product INTEST.pro is an easy-to-use collection kit that can be used comfortably and privately at home. Gut flora analysis Information about one‘s own microorganisms, along with personalized recommendations on how to improve one‘s own microbiota. Detailed report with recommendations 7
  • 9. How Does It Work? 1 2 3 4 5 6 Customer buys INTEST.pro Customer takes a sample Customer sends sample back to BIOMES Microbiome extraction & NGS analysis Profile exploration, including personalized recommendations for the customer Data processing & result matching 8
  • 10. What’s in Each Customer’s Report? 9 Report features: Immune system and wellbeing Vitamin synthesis Calorie harvest Gut microbiome balance Food intolerances Digestion & nutrition uptake Intestinal mucosa Personalized nutrition plans Personalized probiotic supplements
  • 11. The Benefits of our Process INTEST.pro is a quantum leap compared to classical intestinal flora analysis. Measure and quantify the totality of microbes. 2.5B 3.2B unprecedented depth of analysis made possible with DNA sequencing with minimal sample amount unique, curated & proprietary knowledge database (>6,000 studies) personalized report based on the power of community individualized recommendations and personalized nutrition plans 10
  • 12. Where we help PERFORMAN CE & FITNESS Fitness/Nutrition Metabolic/Health 1 DIET & NUTRITION WEIGHT LOSS & OBESITY DIGESTION PROBLEMS IRRITABLE BOWEL SYNDROM What’s wrong & why? How can you get better? 2 3 4 5 11 Wellbeing Spectrum
  • 13. Huge Market Opportunity by example of the e-Health market and Irritable bowel syndrome (IBS) 320 280 240 200 160 120 80 40 0 $ Billions CAGR = 15.8% 2014 2016 2020 2021 2022 Global e-Health market will reach €264 billion by 2022 e-Health: A hot global megatrend Market potential given by IBS in Germany 15 million people in Germany suffer from IBS € 1.94 billion market potential for Germany Additional huge market potential through personalized probiotics Global Market volume of e-Health 12
  • 14. Up-sale Importance: Additional business Market potential: Large Duration: Short-term Informati on Knowledge Data Data & Knowledge Importance: Additional business Market potential: Very large Duration: Long-term Business Model Importance: CORE BUSINESS Market potential: Very large Duration: Short-term DNA Analyses 13 • Probiotic Supplements • Nutrition plans • Lead provision
  • 15. Fast Revenue Growth 14 • Fast growth by market occupation & product diversification • Online CAC at SEA, Facebook ~40 € • Product sale after analytic ~35% • Low COGS down to 10 € per analytic (currently 20 €) • Sales start in summer 2018 with > 250 k€ revenue • Till June >350 k€ revenue in 2019 (>5.200 tests and >2.500 probiotics) • 1.3 Mio. € revenue in 2019 with offline sale deals and internationalization (ENG, FR, ESP) -2.000.000 € -1.500.000 € -1.000.000 € -500.000 € 0 € 500.000 € 1.000.000 € 1.500.000 € 2.000.000 € 2.500.000 € 3.000.000 € 3.500.000 € - € 2.000.000 € 4.000.000 € 6.000.000 € 8.000.000 € 10.000.000 € 12.000.000 € 14.000.000 € 16.000.000 € 18.000.000 € 2018 2019 2020 2021 2022 2023 Revenue COGS Payroll Other expenses EBIT
  • 16. Investment Ask Product diversification Internationalization – Europe and Latin America Marketing & sales activities R&D and user interface improvement Investments already received: Family & Friends 75k€ Oct 2016 EXIST sponsorship 160k€ Jun 2017 Seed round 600k€ Feb 2018 Funding amount Up to 2 Mio. EUR by convertible loan (pre-A) Up to 5 Mio. EUR for series A in Q3 2020 Up to 4 Mio. EUR by public promotion programs (ProFIT) Budget allocation Human resources 15
  • 17. High Professional Team Experienced management team Experienced operational team Dr. Paul Hammer CEO & Founder Andrej Wackerow CCO & Co-Founder Carsten Krumbiegel CTO & Co-Founder Christin Günther CMO & Co-Founder Dr. Tewodros Debebe Aklilu Head of Science Philipp Franke Head of Laboratory Jonas Dierenbach Head of IT & Co-Founder 16
  • 18. We are supported by CONTACT info@BIOMES.world www.BIOMES.world +49 163 474 15 31 Dr. Paul Hammer We are awarded by Alibaba Create Cloud Contest Jerusalem Competition Pitch Marathon