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Stemming demand: how best to
     track the impact of
        interventions?

    Martin Bardsley Adam Steventon
              Nuffield Trust
 Health Strategy Summit March 24th 2010
Monthly number of emergency
admissions in England
Approaches to managing
demand...
• self-management education,      •targeting people at high risk,
• self-monitoring,                •multidisciplinary teams after discharge,
• group visits to primary care,   •nurse-led clinics and nurse-led follow-
• broad managed care              up,
   programmes,                    •assertive case management, home
• integrating social and health   visits.
   care,
                                  • nurse-led clinics,
• multidisciplinary teams in
   hospital,                      • telecare,
• discharge planning,             • telemonitoring.
• multidisciplinary teams after
   discharge,                           But do they work?
• care from specialist nurses,            In your patch?
Challenges of evaluation....

• Difficult to randomise a distinctive treatment and
  control group within the same organisations or service.
• Service delivery patterns may change incrementally
  over time.
• The client/patient group may change over time.
• Randomised trials can be costly and sometimes out of
  proportion to the investment in the change).
• Can be slow – changes need to be made embedded
  and cases followed up for a long time.
• Results may only reflect experiences of a subset of
  users.
Health and social care event timeline
Alternative approaches.......

• Exploits existing data sets – as much as possible. This makes it
  cheaper and easier to set up though it does create its own
  challenges.
• Is continuous and timely. Aiming to provide interim results and
  feedback during throughout the evaluation period. This can
  potentially help fine tune the service – and the measurement
  process.
• Aim to capture events and experiences for as broad a group of
  users and potential users as possible. So looks, to some degree at
  the majority of service users.
• Develops accurate comparative tools – using the right methods to
  identify pseudo control groups as the basis for judging changes
  over time.
• Exploits linked data sets to construct individual patient histories.
Why use routine information?


Advantages                     Disadvantages
• Relatively inexpensive       • May not include the right
• Comprehensive                   information
• Person and event level       • Rely on prior classifications
• Accessible                   • Quality and completeness
• Can be linked into routine      of recording
  management reporting         • Limited range of outcomes
  processes
Two methodological problems



• Regression to the mean: if you select people
  with high service use, their service use will
  probably reduce anyway.
• Cost are highly skewed: a relatively small
  change in very high costs users can have an
  impact.
Average number of emergency bed days
Emerging risk
                                       50


                                       45


                                       40


                                       35


                                       30


                                       25


                                       20


                                       15


                                       10


                                       5


                                       0

                                            -5   -4   -3   -2   -1   Intens   +1   +2   +3   +4
                                                                     e year
Will the next card be higher or
lower?

                             HIGHER


                             LOWER


                             ERRRR??
                        = Regression to the mean in the style of Brucey
The distribution of future
utilisation is exponential
                                  £4,500
Actual Average cost per patient



                                  £4,000


                                  £3,500


                                  £3,000


                                  £2,500


                                  £2,000


                                  £1,500


                                  £1,000


                                   £500


                                      £0
                                           0   10   20       30     40      50     60    70   80   90

                                                         Predicted Risk (centile rank)
Approach 1 WSD trial.
     A randomised trial.


• Study started in 3 sites in 2007. Aim to recruit
  6000 patients to the trial.
• Recruitment to the study ended in Autumn
  2009. Last trial participant reach 12mnths in
  2010.
• Final analyses early 2011.
Are telecare and telehealth part of the solution?
“For every pound spent on telecare, five pounds could be
    saved on expensive hospital and residential care”
                Counsel and Care, 2009
Five evaluation themes
  Theme 1           Theme 2           Theme 3          Theme 4           Theme 5
  (Nuffield          (UCL)              (LSE)        (Manchester)       (Imperial)
   Trust)

   Impact of       Participant-       Costs and      Experiences of   Organisational
  service use       reported            cost-        service users,    factors and
      and         outcomes and      effectiveness       informal       sustainable
  associated         clinical                          carers and     adoption and
 costs for the    effectiveness                       professionals    integration
    NHS and
social services
                    Subset of
                  2,750 people
                   plus 660 of
                  their informal      Subset of       Qualitative      Qualitative
  All 6,000           carers        2,750 people      interviews       interviews
   people
                        Universities of Oxford and Birmingham
Information Flows
                                            Encrypted subset
                        HES/SUS             Client-event based

                                                                      Linked Data Subsets
                                            Encrypted subset
                        GP                  Client-event based        Client Based
Local                                                                 Needs variables
                                                                      (Risk Groups)

Operational             Community           Encrypted subset          Hospital Use
                        Nursing Activity    Client-event based
                                                                      GP & Community
                                                                      Use
Systems
                                            Encrypted subset          Social Care Use
                        Social care         Client-event based
                        Client event data

                                               Person level records



          Demographics Batch
          Service
Ensuring even mix of patients



                        Analysis by risk subgroup
Approach 2. Using case controls
derived from routine data.
                               1
               Access routine data at person level



                              2
                  Construct control groups to
               overcome regression to the mean


                                3
               Regular monitoring and updates to
                 influence policy development
Number of people receiving
intervention per month (4 sites)
Linking participants
 to HES (1)                                IC collates and adds (if
                                           required) NHS
                                           numbers using batch
Participating sites                        tracing
                                                                       Information Centre
 Sites collate patient lists


                                                    IC derives
                                                                         Nuffield Trust
                                                    extra
                                                    identifiers




      Patient identifiers      Trial information (e.g.            Non-patient identifiable keys (e.g.
      (e.g. NHS number)        start and end date)                HES ID, pseudonymised NHS #)
Linking participants
to HES (2)
Profiles of emergency
hospital admissions (1)

                    Start of intervention
Profiles of emergency
hospital admissions (2)

                    Start of intervention
Regression to the mean?
                 50
Average number of emergency


                 45


                 40


                 35


                 30


                 25


                 20
bed days




                 15


                 10


                    5


                    0
                       -5     -4   -3   -2   -1   Intense + 1   +2   +3   +4
                                                    year
Choices about multivariate
matching
•   Draw controls from local area, similar areas or nationally?
•   Which variables to include?
•   What weight to attach to each variables (distance measure)?
•   With or without replacement?
•   1-1 matching or 1-many matching?
•   Caliper matching on certain variables?
Building models every month
    Predictor variables taken from two   ... To predict 12
             previous years....           months ahead
Prevalence of health diagnoses
categories in intervention and
control groups
Comparison of intervention and
 control group
                                            Intervention    Control Standardised
                                                 (N=378)   (N=378)     difference
Proportion aged 85+                                 47%        47%           0.0%
Proportion female                                   68%        68%           0.0%
Mean area-level deprivation score                   16.6      16.2           4.8%
Mean number of emergency admissions in               1.0        0.9          3.0%
previous year
Mean number of emergency admissions in               0.3       0.3          4.0%
previous 30 days
Mean emergency length of stay in previous            8.6       8.7          0.7%
year
Mean number of chronic conditions                   1.6        1.5          4.3%
Mean predictive risk score                         0.25       0.25          0.2%
Overcoming regression to the
mean using a control group (1)

                         Start of intervention
Overcoming regression to the
mean using a control group (2)

                         Start of intervention
Overcoming regression to the
mean using a control group (3)

                         Start of intervention
Overcoming regression to the
mean using a control group (4)

                         Start of intervention
Almost real-time
tracking of intervention
                           PARR score



                           Impact on
                           emergency
                           admissions
                           (number per
                           head over
                           3mths)
Regular evaluation and
monitoring
Discussion points
• What are the rate limiting steps?
  –   Data being available?
  –   The right data to measure what you want?
  –   Skills to analyse data locally?
  –   Analytical resources locally?

• What are the priority interventions for routine
  tracking?
• How should feedback be organised and
  delivered?
• What should only be assessed with
  randomisation?
Thank You

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Martin Bardsley & Adam Steventon: Stemming demand: how best to track the impact of interventions

  • 1. Stemming demand: how best to track the impact of interventions? Martin Bardsley Adam Steventon Nuffield Trust Health Strategy Summit March 24th 2010
  • 2. Monthly number of emergency admissions in England
  • 3. Approaches to managing demand... • self-management education, •targeting people at high risk, • self-monitoring, •multidisciplinary teams after discharge, • group visits to primary care, •nurse-led clinics and nurse-led follow- • broad managed care up, programmes, •assertive case management, home • integrating social and health visits. care, • nurse-led clinics, • multidisciplinary teams in hospital, • telecare, • discharge planning, • telemonitoring. • multidisciplinary teams after discharge, But do they work? • care from specialist nurses, In your patch?
  • 4. Challenges of evaluation.... • Difficult to randomise a distinctive treatment and control group within the same organisations or service. • Service delivery patterns may change incrementally over time. • The client/patient group may change over time. • Randomised trials can be costly and sometimes out of proportion to the investment in the change). • Can be slow – changes need to be made embedded and cases followed up for a long time. • Results may only reflect experiences of a subset of users.
  • 5. Health and social care event timeline
  • 6. Alternative approaches....... • Exploits existing data sets – as much as possible. This makes it cheaper and easier to set up though it does create its own challenges. • Is continuous and timely. Aiming to provide interim results and feedback during throughout the evaluation period. This can potentially help fine tune the service – and the measurement process. • Aim to capture events and experiences for as broad a group of users and potential users as possible. So looks, to some degree at the majority of service users. • Develops accurate comparative tools – using the right methods to identify pseudo control groups as the basis for judging changes over time. • Exploits linked data sets to construct individual patient histories.
  • 7. Why use routine information? Advantages Disadvantages • Relatively inexpensive • May not include the right • Comprehensive information • Person and event level • Rely on prior classifications • Accessible • Quality and completeness • Can be linked into routine of recording management reporting • Limited range of outcomes processes
  • 8. Two methodological problems • Regression to the mean: if you select people with high service use, their service use will probably reduce anyway. • Cost are highly skewed: a relatively small change in very high costs users can have an impact.
  • 9. Average number of emergency bed days Emerging risk 50 45 40 35 30 25 20 15 10 5 0 -5 -4 -3 -2 -1 Intens +1 +2 +3 +4 e year
  • 10. Will the next card be higher or lower? HIGHER LOWER ERRRR?? = Regression to the mean in the style of Brucey
  • 11. The distribution of future utilisation is exponential £4,500 Actual Average cost per patient £4,000 £3,500 £3,000 £2,500 £2,000 £1,500 £1,000 £500 £0 0 10 20 30 40 50 60 70 80 90 Predicted Risk (centile rank)
  • 12. Approach 1 WSD trial. A randomised trial. • Study started in 3 sites in 2007. Aim to recruit 6000 patients to the trial. • Recruitment to the study ended in Autumn 2009. Last trial participant reach 12mnths in 2010. • Final analyses early 2011.
  • 13. Are telecare and telehealth part of the solution? “For every pound spent on telecare, five pounds could be saved on expensive hospital and residential care” Counsel and Care, 2009
  • 14. Five evaluation themes Theme 1 Theme 2 Theme 3 Theme 4 Theme 5 (Nuffield (UCL) (LSE) (Manchester) (Imperial) Trust) Impact of Participant- Costs and Experiences of Organisational service use reported cost- service users, factors and and outcomes and effectiveness informal sustainable associated clinical carers and adoption and costs for the effectiveness professionals integration NHS and social services Subset of 2,750 people plus 660 of their informal Subset of Qualitative Qualitative All 6,000 carers 2,750 people interviews interviews people Universities of Oxford and Birmingham
  • 15. Information Flows Encrypted subset HES/SUS Client-event based Linked Data Subsets Encrypted subset GP Client-event based Client Based Local Needs variables (Risk Groups) Operational Community Encrypted subset Hospital Use Nursing Activity Client-event based GP & Community Use Systems Encrypted subset Social Care Use Social care Client-event based Client event data Person level records Demographics Batch Service
  • 16. Ensuring even mix of patients Analysis by risk subgroup
  • 17. Approach 2. Using case controls derived from routine data. 1 Access routine data at person level 2 Construct control groups to overcome regression to the mean 3 Regular monitoring and updates to influence policy development
  • 18. Number of people receiving intervention per month (4 sites)
  • 19. Linking participants to HES (1) IC collates and adds (if required) NHS numbers using batch Participating sites tracing Information Centre Sites collate patient lists IC derives Nuffield Trust extra identifiers Patient identifiers Trial information (e.g. Non-patient identifiable keys (e.g. (e.g. NHS number) start and end date) HES ID, pseudonymised NHS #)
  • 21. Profiles of emergency hospital admissions (1) Start of intervention
  • 22. Profiles of emergency hospital admissions (2) Start of intervention
  • 23. Regression to the mean? 50 Average number of emergency 45 40 35 30 25 20 bed days 15 10 5 0 -5 -4 -3 -2 -1 Intense + 1 +2 +3 +4 year
  • 24. Choices about multivariate matching • Draw controls from local area, similar areas or nationally? • Which variables to include? • What weight to attach to each variables (distance measure)? • With or without replacement? • 1-1 matching or 1-many matching? • Caliper matching on certain variables?
  • 25. Building models every month Predictor variables taken from two ... To predict 12 previous years.... months ahead
  • 26. Prevalence of health diagnoses categories in intervention and control groups
  • 27. Comparison of intervention and control group Intervention Control Standardised (N=378) (N=378) difference Proportion aged 85+ 47% 47% 0.0% Proportion female 68% 68% 0.0% Mean area-level deprivation score 16.6 16.2 4.8% Mean number of emergency admissions in 1.0 0.9 3.0% previous year Mean number of emergency admissions in 0.3 0.3 4.0% previous 30 days Mean emergency length of stay in previous 8.6 8.7 0.7% year Mean number of chronic conditions 1.6 1.5 4.3% Mean predictive risk score 0.25 0.25 0.2%
  • 28. Overcoming regression to the mean using a control group (1) Start of intervention
  • 29. Overcoming regression to the mean using a control group (2) Start of intervention
  • 30. Overcoming regression to the mean using a control group (3) Start of intervention
  • 31. Overcoming regression to the mean using a control group (4) Start of intervention
  • 32. Almost real-time tracking of intervention PARR score Impact on emergency admissions (number per head over 3mths)
  • 34. Discussion points • What are the rate limiting steps? – Data being available? – The right data to measure what you want? – Skills to analyse data locally? – Analytical resources locally? • What are the priority interventions for routine tracking? • How should feedback be organised and delivered? • What should only be assessed with randomisation?