The newsletter provides information from the International Senologic and Oncologic Scientific Community (ISOCS). It highlights recent literature on breast cancer screening and treatment approaches. It also announces upcoming conferences and workshops. The newsletter aims to connect medical specialists around the world to discuss cancer research and improve patient care.

1. 6HQRORJRUJ 1HZVOHWWHU
,QWHUQDWLRQDO 6HQRORJLF DQG 2QFRORJLF¬ 6FLHQWLILF RPPXQLW ,626

2. ¬
RQQHFWLQJ VSHFLDOLVWV ZRUOGZLGH
0D
(GLWRULQKLHI *LDQ 3DROR $QGUHROHWWL 0'
Join us on LinkedIn, Twitter, Facebook, YouTube, ResearchGate, SlideShare, Flickr, and share comments.
Read Senology Newspaper daily
Senology collaborates with
Literature Selection
z Venturini E et al.: Tailored Breast Cancer Screening Program with Microdose Mammography, US, and
MR Imaging: Short-term Results of a Pilot Study in 40-49-Year-Old Women, Radiology. 2013 Apr 11.
[Epub ahead of print]
z Girardi V et al.: Breast ultrasound in 22,131 asymptomatic women with negative mammography,
Breast. 2013 Apr 1 [Epub ahead of print]
z Nelson H et al.: Use of medications to reduce risk for primary breast cancer: a systematic review for
the u.s. Preventive services task force, Ann Intern Med. 2013 Apr 16;158(8):604-14
z Heemskerk-Gerritsen BA et al.: Substantial breast cancer risk reduction and potential survival benefit
after bilateral mastectomy when compared with surveillance in healthy BRCA1 and BRCA2 mutation
carriers: a prospective analysis, Ann Oncol. 2013 Apr 10. [Epub ahead of print]
z Li J et al.: Mammographic Density Reduction Is a Prognostic Marker of Response to Adjuvant
Tamoxifen Therapy in Postmenopausal Patients With Breast Cancer, J Clin Oncol. 2013 Apr 22.
[Epub ahead of print]
z Lazzeroni M et al.: Tailoring treatment for ductal intraepithelial neoplasia of the breast according to
Ki-67 and molecular phenotype, Br J Cancer. 2013 Apr 11 [Epub ahead of print]
z Zagouri F et al.: Intrathecal administration of trastuzumab for the treatment of meningeal
carcinomatosis in HER2-positive metastatic breast cancer: a systematic review and pooled analysis,
Page 1 of 3Senology Newsletter
02/05/2013file://C:Documents and SettingsutenteDesktopSenology Newsletter ay.htm

3. Breast Cancer Res Treat. 2013 Apr 16. [Epub ahead of print]
z Chen X et al.: Analysis in early stage triple-negative breast cancer treated with mastectomy without
adjuvant radiotherapy: Patterns of failure and prognostic factors, Cancer. 2013 Apr 10. doi:
10.1002/cncr.28085. [Epub ahead of print]
Questions and Answers
z Breast Cancer Workshop Summary - with Cynthia Ma, Washington University School of Medicine͕ St. Louis,
MO, USA
Discussion
z Even in women with breast tumours of excellent prognosis, local recurrence after conservative surgery
without adjuvant therapy is very high - Share your opinion on LinkedIn
Fragments of History
z 1981 - Umberto Veronesi, National Cancer Institute, Milan, Italy: A number of different factors may explain the
progressive development of new procedures for conservative treatment of breast cancer. The first factor is a
better understanding of the natural history of breast cancer and of the fact that the results of treatment are
influenced more by distant spread when it occurs than by local or regional control of the disease. The second
is the discovery of increasing numbers of cancers of minimal dimensions by means of new diagnostic
techniques, especially mammography. The third is the more pressing demand for less mutilating procedures
and the increasing requests from patients to be informed of the various possible treatments, including the
conservative techniques. Finally, there is a widespread belief that if a conservative treatment could be offered
to women with early breast cancer, it would represent a tremendous tool for publicizing self-examination of the
breasts and alertness in seeking medical advice at the first appearance of a lump in the breast. (Veronesi U
et al.: Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in
patients with small cancers of the breast, N Engl J Med.1981Jul 2;305(1):6-11)
Calendar of Events
z 5th IMPAKT Breast Cancer Conference, May 2-4, 2013, Brussels, Belgium
z Precision Medicines in Breast Cancer, May 9-10, 2013, London, UK
z 15th Milan Breast Cancer Conference, June 20-21, 2013, Milan, Italy
z 3rd World Congress on Cancer Science Therapy, October 21-23, 2013, San Francisco, CA, USA - in
Partnership with Senology
z 9th Meet the Professor. Advanced International Breast Cancer Conference (AIBCC), November 11-13,
Padova, Italy - under the Patronage of Senology
z Update in Breast Imaging, 22-23 November, Ostend, Belgium
Literature Selection
z Su VY et al.: Amiodarone and the risk of cancer: A nationwide population-based study, Cancer. 2013
Apr 8. doi: 10.1002/cncr.27881. [Epub ahead of print]
z Raaschou P et al.: Rheumatoid arthritis, anti-tumour necrosis factor therapy, and risk of malignant
melanoma: nationwide population based prospective cohort study from Sweden, BMJ. 2013 Apr
8;346:f1939
z Xing M et al.: Association between BRAF V600E mutation and mortality in patients with papillary
thyroid cancer, JAMA. 2013 Apr 10;309(14):1493-501
z Dorffel W et al.: Treatment of Children and Adolescents With Hodgkin Lymphoma Without
Radiotherapy for Patients in Complete Remission After Chemotherapy: Final Results of the
Multinational Trial GPOH-HD95, J Clin Oncol. 2013 Apr 20;31(12):1562-8
Editorial
z Core needle biopsy for thyroid nodules with previous non-diagnostic fine needle aspiration, Jung
Hwan Baek, Department of Radiology and Research Institute of Radiology, University of Ulsan College of
Page 2 of 3Senology Newsletter
02/05/2013file://C:Documents and SettingsutenteDesktopSenology Newsletter ay.htm

4. ¬¬¬¬¬
ZZZVHQRORJRUJ
Medicine, Asan Medical Center, Seoul, Korea
Core needle biopsy (CNB) for thyroid nodules with previous non-diagnostic fine needle aspiration (FNA)
results showed a low incidence (1.3%, 2/155) of non-diagnostic results. CNB also showed high diagnostic
values for neoplasm and malignancy. In addition, CNB could prevent unnecessary diagnostic surgery in 96%
(22 of 23) of patients with repeated nondiagnostic FNA results. This result suggests that CNB is a viable
method of choice for the reliable diagnosis of thyroid nodules for which previous FNA results were
nondiagnostic
(Commentary on: Yeon JS et al.: Thyroid Nodules with Initially Nondiagnostic Cytologic Results: The
Role of Core-Needle Biopsy, Radiology 2013 Mar 22 [Epub ahead of print])
Questions and Answers
z Kidney Cancer Workshop Summary - with Sumanta Kumar, City of Hope, Duarte, CA, USA
z Lung Cancer Workshop Summary - with Jared Weiss, University of North Carolina, Chapel Hill, NC, USA
z Stem Cell Workshop Summary - with Anthony Stein, City of Hope, Duarte, CA, USA
Subscribe Unsubscribe Contact Back Issues
Page 3 of 3Senology Newsletter
02/05/2013file://C:Documents and SettingsutenteDesktopSenology Newsletter ay.htm