Key lessons learned from the worldwide pandemic
Keynote presentation at the Digital Transformation of Pharmaceutical Industry conference organised by United Journal and Conferences on April 13th 2021
2. TABLE OF CONTENTS
1 Early impacts of the pandemic
2 Key lessons learned
3 Reinventing the pharmaceutical industry
3. When the wind of
change blows,
some build walls
while other build
windmills
- old proverb-
4. EARLY IMPACTS OF THE PANDEMIC
• Millions of people put on strict lockdown in China
• Only in China…will not hit us in our countries…
• Is just like a flu… will come and go…
• Unpreparedness of the western world
• People hospitalized, death rate increasing
• Very contagious
• Lots of unknowns about the virus
• Social distancing measures implemented
• “Freedom” restrictions
• Unemployment rates increasing
• Increasing mental health challenges
• Etc…
PEOPLE
5. EARLY IMPACTS OF THE PANDEMIC
• China, the factory of the world on hold…
• Personal Protective Equipment (PPE) shortages
• Masks
• Blouses
• Gloves
• Etc…
• Ventilators for intensive care patients
• Sanitizing products
• Consumer goods
• Bikes
• Propane
• Increased counterfeighting
• Etc…
PRODUCTS
6. EARLY IMPACTS OF THE PANDEMIC
• China ”closing down” the whole country
• China building a new hospital in 10 days
• Uncoordinated measures across countries
• Closing borders
• Closing airports
• Stopping business and leisure travels
• Introducing lockdowns, curfew, fines etc…
• Local hospitals rapidly overwhelmed
• Competition for supplies even on tarmacs
• Blocking vaccines supplies in countries
• Releasing billions to subsidy the economy
• Strong populism push
• Etc…
COUNTRIES
7. EARLY IMPACTS OF THE PANDEMIC
• Shortages of products coming from China
• Active Pharmaceutical Ingredients (API)
• Lab material
• Machines
• Packaging material
• Etc…
• Supply Chain planning
• Manufacturing plants shutdown
• Distribution and logistics stopped
• Working from home
• Country lockdowns
• Etc…
PHARMACEUTICAL COMPANIES
8. TABLE OF CONTENTS
1 Early impacts of the pandemic
2 Key lessons learned
3 Reinventing the pharmaceutical industry
10. KEY LESSONS LEARNED
• Cultural differences
• Masks
• Lockdowns
• Etc…
• Increased focus on health and wellbeing
• Hygiene
• Exercising and back to nature
• Etc…
• Importance of our social life
• Working from home
• Remote education
• Etc…
PEOPLE
11. KEY LESSONS LEARNED
• Reviewing our globalization model
• Relocalization
• Diversification
• Direct or local distribution networks
• Etc…
• Physical world blending with the digital one
• Online vs offline
• eCommerce
• Online gaming
• Videoconferencing
• Etc…
• New spending habits
• Etc…
PRODUCTS
12. KEY LESSONS LEARNED
• Authoritarian vs democratic governments
• Health driven vs economy
• Strategy alignment between countries
• Closing borders
• Travelling
• Testing & vaccination strategy
• Etc..
• Inequalities amongst continents/countries
• Wealth
• Access to healthcare
• Etc…
COUNTRIES
13. KEY LESSONS LEARNED
• In the race to find solutions to COVID-19, many
science organizations have been developing:
• Faster diagnostics
• Life-saving therapies
• Effective vaccines
• Innovative products and technologies
• Etc…
• Anticipating rapid change, designs focused on
adaptability and flexibility are enabling nimble
innovation under the urgent pressure to lead
the world out of this crisis
PHARMACEUTICAL COMPANIES 1/2
14. KEY LESSONS LEARNED
• Key sourcing dependencies
• Active Pharmaceutical Ingredients (API)
• Raw materials
• Etc…
• Rise of Biotech companies
• BioNTech
• Moderna
• Etc…
• Building Pharma plants in record times
• Accelerating the regulator approvals
• New ways of working
• Etc…
PHARMACEUTICAL COMPANIES 2/2
15. TABLE OF CONTENTS
1 Early impacts of the pandemic
2 Key lessons learned
3 Reinventing the pharmaceutical industry
16. A crisis is an
opportunity
riding the
dangerous wind
- old proverb -
17. In 1959, John F. Kennedy, then still a senator, explained in a speech that “when written in Chinese, the word
‘crisis’ is composed of two characters – one represents danger and one represents ‘opportunity.”
18. REINVENTING THE PHARMACEUTICAL INDUSTRY
• Life Sciences jobs trends
• Innovations
• Sciences and technologies
• Increasing demand
• Etc…
• People development and education
• Mainly online
• Adaptive lifelong learnings
• Etc…
• Working from home
• Distributed workforces
• Etc…
PEOPLE
19. REINVENTING THE PHARMACEUTICAL INDUSTRY
• Genomics based treatments
• CAR-T for cancer treatments
• mRNA vaccines (for COVID but also malaria, AIDS
and others)
• Etc..
• Affordability
• e.g. CAR-T (alpha beta vs gamma delta T cells)
= $450’000 vs $40’000
• Digital therapeutics
• Fighting increasing counterfeiting
• Etc…
PHARMACEUTICAL PRODUCTS
20. REINVENTING THE PHARMACEUTICAL INDUSTRY
• Evolution of workplaces and physical sites
• “Dematerialization” of the workplaces
• Rethinking the big Pharma campus concept
• Etc…
• Virtual meetings being the standard
• Moving the office coffee machine to our home
• Like cooking at home vs going to the restaurant
• Etc…
WORKPLACES - OFFICES
21. REINVENTING THE PHARMACEUTICAL INDUSTRY
• Scientists working in new ways
• Digital R&D labs
• Labs becoming innovation and collaboration hubs
• Co-development and co-creation
• Etc…
• Virtual clinical trials
• Faster time to market for drug discovery
• Etc…
WORKPLACES – R&D
22. REINVENTING THE PHARMACEUTICAL INDUSTRY
• Shared manufacturing sites - big pharma plants
becoming subcontracting sites
• Smart manufacturing acceleration
• IoT (Internet of Things)
• AIoT (Artificial Intelligence of Things)
• RPA (Robotic Process Automation)
• Digital twins
• Etc…
• Flexibility, agility and adaptability
• Personalized medicines
• Precision medicines (e.g. CAR-T where patient blood
is the raw material and finished product)
• Should the material move around or the know-how?
• Etc…
WORKPLACES – SUPPLY CHAIN
23. REINVENTING THE PHARMACEUTICAL INDUSTRY
• Rise of BioTech companies
• Big Pharma vs smaller companies
• Collaboration vs competition
• Building collaborative ecosystems
• People and networks (e.g. Moderna/Lonza)
• Etc…
• Big data / Artificial Intelligence / Machine Learning
• Cross-convergence
• Apple, Amazon, Google, Microsoft…
• Wallmart…
• Data privacy and ownership
• Mental health
• Etc…
PHARMACEUTICAL COMPANIES
24. REINVENTING THE PHARMACEUTICAL INDUSTRY
• DigiTech Pharma 2018 in London
• New Insights through additional new data and data points
including x-convergence from social media
• New discoveries and treatments
• Easier, quicker and more efficient clinical trials onboarding
• Expedite drug to market process
• Personalized medicines
• Earlier diagnosis
• Broader access to drugs and healthcare (towards UHC
targets)
• Improved Pharmacovigilance
• Emergence of new healthcare ecosystem
KEY TRENDS
25. REINVENTING THE PHARMACEUTICAL INDUSTRY
• Six main actors
• Drugs & Devices
• Healthcare providers
• Clinical support
• Regulators
• Payers
• Patients
• Which are the most powerful actors?
• Big Pharma?
• Regulators?
• Payers?
HEALTHCARE ECOSYSTEM
PROVIDERS
(Doctors,
Pharmacies,
Hospitals...)
DRUGS &
DEVICES
PATIENTS
PAYERS
(Public or
Private)
CLINICAL
SUPPORT
(Trials,
Analytics...)
REGULATORS
(FDA, EMA…)
26. REINVENTING THE PHARMACEUTICAL INDUSTRY
• New business models
• Personalized and precision medicines
• Outcome based pricing
• Rendanheyi for Pharma?
PATIENT CENTRICITY
PROVIDERS
(Doctors,
Pharmacies,
Hospitals...)
DRUGS &
DEVICES
PATIENTS
PAYERS
(Public or
Private)
CLINICAL
SUPPORT
(Trials,
Analytics...)
REGULATORS
(FDA, EMA…)
27. REINVENTING THE PHARMACEUTICAL INDUSTRY
• New business model developed by Haier
Group’s CEO Zhang Ruimin
• Ren (people) refers to employees
• Dan (order) refers to the user value
• HeYi (combination) means combining the user
value realization with created user value
• It is like creating a network of entrepreneurs
within the company rather than the traditional
pyramidal organization
• Today the Haier Group is like an ecosystem of
hundreds interacting companies
RENDANHEYI
28. • Patients receive care. Consumers make choices
• Moving from patient data only to consumer
data driven
• Preventive care vs healthcare (sick care?)
• Influenced by communities
• Increased importance of brands
• BioNTech
• Moderna
• Pfizer
• Astra Zenecca
CONSUMERS
REINVENTING THE PHARMACEUTICAL INDUSTRY
CONSUMERIZATION
PATIENTS
DRUGS &
DEVICES
PROVIDERS
(Doctors,
Pharmacies,
Hospitals...)
PAYERS
(Public or
Private)
CLINICAL
SUPPORT
(Trials,
Analytics...)
REGULATORS
(FDA, EMA…)
29. NEWS &
SOCIAL MEDIA
• Media/social media
• Fake news
• Popularization
• Education
• Pharmacovigilance
• Trust
• Ethics
• Politics
CONSUMERS
REINVENTING THE PHARMACEUTICAL INDUSTRY
MEDIATIZATION
PATIENTS
DRUGS &
DEVICES
PROVIDERS
(Doctors,
Pharmacies,
Hospitals...)
PAYERS
(Public or
Private)
CLINICAL
SUPPORT
(Trials,
Analytics...)
REGULATORS
(FDA, EMA…)
