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Open Fractures and BOAST
Guidelines
“Most open tibial/ femoral fractures are caused
by high impact trauma, so the potential for
concomitant life-threatening injury should be
ruled out before addressing traumatic limb
injury”
The classification of such soft-
tissue wounding is according
to two systems, namely that
of Gustilo, Mendoza &
Williams (See: Gustilo RB,
Mendoza RM, Williams DN
(1984) Problems in the
management of type III
(severe) open fractures
In 1895, Stanley Boyd said
“The most important
divisions of fractures -
simple, compound and
complicated - are based
upon the condition of the
soft parts.”
Open fracture simplified
Gustillo Classification I
wound contamina
tion
Soft
tissue
injury
BONE
INJURY
TIME
(week
s)
risk of
infecti
on in
%
<1cm minimal Minimal Simple
minimal
comminut
ion
15 0-2
Court-Brown et al. 1990
Patzakis MJ et al. 1989 77/1104 – early ABx
Gustillo Classification II
wound contaminat
ion
Soft
tissue
injury
BONE
INJURY
TIME
(week
s)
risk of
infecti
on in
%
1-10cms Moderate Moderat
e to
some
muscle
damage
Moderate
comminuti
on
24 2-5
Court-Brown et al. 1990
Patzakis MJ et al. 1989 77/1104 – early ABx
Gustillo Classification IIIA wound contamina
tion
Soft
tissue
injury
BONE
INJURY
TIME
(week
s)
risk of
infecti
on in
%
>10cms High Moderat
e to
some
muscle
damage
Usually
comminut
ed
Soft tissue
coverage
may be
possible
27 5-10
Patzakis MJ et al. 1989 77/1104 – early ABx
Gustillo Classification IIIB
wound contaminati
on
Soft tissue
injury
BONE
INJURY
TIME
(weeks
)
risk of
infectio
n in %
>10cms High Very
severe,
Loss of
coverage
Requires
reconstruc
tive
surgery
Poor bone
cover
Moderate to
severe
comminutio
n
38 10-50
Gustillo Classification IIIc
wound contaminati
on
Soft
tissue
injury
BONE
INJURY
TIME
(weeks
)
risk of
infecti
on in
%
>10cms High Very
severe
Loss of
coverage
Vascular
injury
Soft tissue
reconstru
ctive
surgery
Poor bone
cover
Moderate
to severe
comminutio
n
74 25-50
OTA classification
Parameter Score
Injury to skin Small injury
Large/Immeasurable injury
Degloving injury
1
2
3
Muscular injury No/Minimal injury
Moderate/functional injury
Extensive muscle injury
1
2
3
Arterial injury No injury
Non-ischaemic injury
Ischaemia
1
2
4
Degree of contamination No/minimal contamination
Surface
Deep
1
2
3
Amount of bone loss No loss
Minimal bone loss
Significant bone loss
1
2
3
Ganga hospital scoring
Parameter Score
Skin losses No loss
Some loss/degloved
(+2 to above if over bone)
Extensive loss/exposed bone
1
2
5
Soft tissue injury No injury
Repairable
Irreparable
Loss of <2 compartments
Loss of ⩾2 compartments
1
2
3
4
5
Bony injury Fracture, no bone loss
Joint involvement
Bone losses: < 4cm
> 4cm
1 - 2
3
4
5
Additional risk factors Age >65
Contamination
Chronic illness
Systemic injury
Other trauma
+2 for each
Epidemiology
Diaphyseal fractures are more common than metaphyseal
fractures
Highest rates of diaphyseal fractures were seen in:
• Tibia 21.6%
• Femur 12.1%
• Radius and Ulna 9.3%
• Humerus 5.7%
EFORT Open ReviewsVolume 3, Issue 5, May 2018, Pages 316-325
https://doi.org/10.1302/2058-5241.3.170072
Annual incidence of 3.4 per 100 000
The mean age of those who sustain open tibial fractures is 43.3
years, most frequently occurring in young adult males and
elderly females.
High energy trauma is the primary mechanism of injury, with
over 50% of cases being attributed to road traffic accidents or
falls from a great height
Microbiology
• Poor tissue oxygenation & devitalisation of the surrounding tissues
including the bone provide a perfect medium for infection and
bacterial multiplication
• When left open >2 weeks – Wound is prone to nosocomial infection
such as pseudomonas species and gram negative species
• This phenomenon of hospital acquired infection emphasizes the
importance of a strict protocol for in-hospital management and early
wound coverage
Choice of antibiotics
• BOAST guidelines
• Start within 3 hours and continue until debridement
• Co-Amoxiclav 1.2g TDS IV
• OR Cefuroxime 1.5g TDS IV
• OR Clindamycin 600mg QDS IV if penicillin allergic
• Stat dose at wound excision and continue for 72
hours or until wound closure whichever is sooner
• Co-amoxiclav 1.2g TDS IV and Gentamicin
1.5mg/Kg
Management in theatre
1. Aggressive debridement and irrigation
• Low pressure lavage using NaCl 0.9%. 3L, 6L or 9L
• Remove bone fragments without soft tissue
attachments
2. Fracture stabilisation – Internal or external
3. Staged debridement – every 24 to 48 hours
as needed
4. Early soft tissue coverage or wound closure
• Aim for less than 7 days to decrease risk of infection
5. Place antibiotic bead pouch in dirty wounds
Case-1
Case 2
Type 2 open fractures both radius and ulna
Case 3
Type 3 A
Case- 4
Gustilo Anderson –Type 3 B
Case -5
Grade IIIC open Tibial shaft fracture clinical photo
External fixators
Case 6
“Mangled” refers to a
limb in which three of
the four functional
components (bone,
vessels, nerves, and soft
tissue) are injured
Take home message
• IV Antibiotics within 3 hours of injury and continue for 72 hours or
until closure
• Serial neurovascular examinations
• Vascular repair ≤6 hours
• Multidisciplinary team (Plastics and Orthopaedics) to treat complex
open fractures
• Wound is handled to remove gross contamination and allow
photography  cover with saline soaked gauze and impermeable film
• Early transfer of patients to specialised centres
• Definitive stabilisation and wound clover within 72 hours and not
exceed 7 days
Morris R,Jones NC,Pallister I, The use of personalised patient information leaflets to improve patients' perceived understanding following open fractures. European journal of
orthopaedic surgery [PubMed PMID: 30368617]
[2]
Mebert RV,Klukowska-Roetzler J,Ziegenhorn S,Exadaktylos AK, Push scooter-related injuries in adults: an underestimated threat? Two decades analysed by an emergency
department in the capital of Switzerland. BMJ open sport [PubMed PMID: 30364432]
[3]
Simpson AHRW,Tsang STJ, Non-union after plate fixation. Injury. 2018 Jun [PubMed PMID: 29929699]
[4]
Haeberle HS,Navarro SM,Power EJ,Schickendantz MS,Farrow LD,Ramkumar PN, Prevalence and Epidemiology of Injuries Among Elite Cyclists in the Tour de France. Orthopaedic
journal of sports medicine. 2018 Sep [PubMed PMID: 30202769]
[5]
Weber CD,Hildebrand F,Kobbe P,Lefering R,Sellei RM,Pape HC, Epidemiology of open tibia fractures in a population-based database: update on current risk factors and clinical
implications. European journal of trauma and emergency surgery : official publication of the European Trauma Society. 2018 Feb 2 [PubMed PMID: 29396757]
[6]
Lovalekar M,Abt JP,Sell TC,Lephart SM,Pletcher E,Beals K, Accuracy of recall of musculoskeletal injuries in elite military personnel: a cross-sectional study. BMJ open. 2017 Dec 14
[PubMed PMID: 29247087]
[7]
Santos AL,Nitta CT,Boni G,Sanchez GT,Tamaoki MJS,Reis FBD, EVALUATION AND COMPARISON OF OPEN AND CLOSED TIBIA SHAFT FRACTURES IN A QUATERNARY REFERENCE
CENTER. Acta ortopedica brasileira. 2018 May-Jun [PubMed PMID: 30038546]
[8]
Oliveira RV,Cruz LP,Matos MA, Comparative accuracy assessment of the Gustilo and Tscherne classification systems as predictors of infection in open fractures. Revista brasileira de
ortopedia. 2018 May-Jun [PubMed PMID: 29892582]
[9]
M'Bra KI,Kouassi AAN,Sery BJLN,Yao LB,Kouassi KJE,Ochou PG Jr,Asséré YAGRA,Lohourou GF,Krah KL,Kodo M, [Secondary amputation of the limb after primary surgery of open
fractures of the lower limb]. The Pan African medical journal. 2018 [PubMed PMID: 30050636]
THANK
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Open fractures ppt

  • 1. Open Fractures and BOAST Guidelines “Most open tibial/ femoral fractures are caused by high impact trauma, so the potential for concomitant life-threatening injury should be ruled out before addressing traumatic limb injury”
  • 2. The classification of such soft- tissue wounding is according to two systems, namely that of Gustilo, Mendoza & Williams (See: Gustilo RB, Mendoza RM, Williams DN (1984) Problems in the management of type III (severe) open fractures In 1895, Stanley Boyd said “The most important divisions of fractures - simple, compound and complicated - are based upon the condition of the soft parts.”
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  • 6. Gustillo Classification I wound contamina tion Soft tissue injury BONE INJURY TIME (week s) risk of infecti on in % <1cm minimal Minimal Simple minimal comminut ion 15 0-2 Court-Brown et al. 1990 Patzakis MJ et al. 1989 77/1104 – early ABx
  • 7. Gustillo Classification II wound contaminat ion Soft tissue injury BONE INJURY TIME (week s) risk of infecti on in % 1-10cms Moderate Moderat e to some muscle damage Moderate comminuti on 24 2-5 Court-Brown et al. 1990 Patzakis MJ et al. 1989 77/1104 – early ABx
  • 8. Gustillo Classification IIIA wound contamina tion Soft tissue injury BONE INJURY TIME (week s) risk of infecti on in % >10cms High Moderat e to some muscle damage Usually comminut ed Soft tissue coverage may be possible 27 5-10 Patzakis MJ et al. 1989 77/1104 – early ABx
  • 9. Gustillo Classification IIIB wound contaminati on Soft tissue injury BONE INJURY TIME (weeks ) risk of infectio n in % >10cms High Very severe, Loss of coverage Requires reconstruc tive surgery Poor bone cover Moderate to severe comminutio n 38 10-50
  • 10. Gustillo Classification IIIc wound contaminati on Soft tissue injury BONE INJURY TIME (weeks ) risk of infecti on in % >10cms High Very severe Loss of coverage Vascular injury Soft tissue reconstru ctive surgery Poor bone cover Moderate to severe comminutio n 74 25-50
  • 11. OTA classification Parameter Score Injury to skin Small injury Large/Immeasurable injury Degloving injury 1 2 3 Muscular injury No/Minimal injury Moderate/functional injury Extensive muscle injury 1 2 3 Arterial injury No injury Non-ischaemic injury Ischaemia 1 2 4 Degree of contamination No/minimal contamination Surface Deep 1 2 3 Amount of bone loss No loss Minimal bone loss Significant bone loss 1 2 3
  • 12. Ganga hospital scoring Parameter Score Skin losses No loss Some loss/degloved (+2 to above if over bone) Extensive loss/exposed bone 1 2 5 Soft tissue injury No injury Repairable Irreparable Loss of <2 compartments Loss of ⩾2 compartments 1 2 3 4 5 Bony injury Fracture, no bone loss Joint involvement Bone losses: < 4cm > 4cm 1 - 2 3 4 5 Additional risk factors Age >65 Contamination Chronic illness Systemic injury Other trauma +2 for each
  • 13. Epidemiology Diaphyseal fractures are more common than metaphyseal fractures Highest rates of diaphyseal fractures were seen in: • Tibia 21.6% • Femur 12.1% • Radius and Ulna 9.3% • Humerus 5.7% EFORT Open ReviewsVolume 3, Issue 5, May 2018, Pages 316-325 https://doi.org/10.1302/2058-5241.3.170072 Annual incidence of 3.4 per 100 000 The mean age of those who sustain open tibial fractures is 43.3 years, most frequently occurring in young adult males and elderly females. High energy trauma is the primary mechanism of injury, with over 50% of cases being attributed to road traffic accidents or falls from a great height
  • 14. Microbiology • Poor tissue oxygenation & devitalisation of the surrounding tissues including the bone provide a perfect medium for infection and bacterial multiplication • When left open >2 weeks – Wound is prone to nosocomial infection such as pseudomonas species and gram negative species • This phenomenon of hospital acquired infection emphasizes the importance of a strict protocol for in-hospital management and early wound coverage
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  • 17. Choice of antibiotics • BOAST guidelines • Start within 3 hours and continue until debridement • Co-Amoxiclav 1.2g TDS IV • OR Cefuroxime 1.5g TDS IV • OR Clindamycin 600mg QDS IV if penicillin allergic • Stat dose at wound excision and continue for 72 hours or until wound closure whichever is sooner • Co-amoxiclav 1.2g TDS IV and Gentamicin 1.5mg/Kg
  • 18. Management in theatre 1. Aggressive debridement and irrigation • Low pressure lavage using NaCl 0.9%. 3L, 6L or 9L • Remove bone fragments without soft tissue attachments 2. Fracture stabilisation – Internal or external 3. Staged debridement – every 24 to 48 hours as needed 4. Early soft tissue coverage or wound closure • Aim for less than 7 days to decrease risk of infection 5. Place antibiotic bead pouch in dirty wounds
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  • 23. Type 2 open fractures both radius and ulna
  • 29. Grade IIIC open Tibial shaft fracture clinical photo
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  • 34. “Mangled” refers to a limb in which three of the four functional components (bone, vessels, nerves, and soft tissue) are injured
  • 35. Take home message • IV Antibiotics within 3 hours of injury and continue for 72 hours or until closure • Serial neurovascular examinations • Vascular repair ≤6 hours • Multidisciplinary team (Plastics and Orthopaedics) to treat complex open fractures • Wound is handled to remove gross contamination and allow photography  cover with saline soaked gauze and impermeable film • Early transfer of patients to specialised centres • Definitive stabilisation and wound clover within 72 hours and not exceed 7 days
  • 36. Morris R,Jones NC,Pallister I, The use of personalised patient information leaflets to improve patients' perceived understanding following open fractures. European journal of orthopaedic surgery [PubMed PMID: 30368617] [2] Mebert RV,Klukowska-Roetzler J,Ziegenhorn S,Exadaktylos AK, Push scooter-related injuries in adults: an underestimated threat? Two decades analysed by an emergency department in the capital of Switzerland. BMJ open sport [PubMed PMID: 30364432] [3] Simpson AHRW,Tsang STJ, Non-union after plate fixation. Injury. 2018 Jun [PubMed PMID: 29929699] [4] Haeberle HS,Navarro SM,Power EJ,Schickendantz MS,Farrow LD,Ramkumar PN, Prevalence and Epidemiology of Injuries Among Elite Cyclists in the Tour de France. Orthopaedic journal of sports medicine. 2018 Sep [PubMed PMID: 30202769] [5] Weber CD,Hildebrand F,Kobbe P,Lefering R,Sellei RM,Pape HC, Epidemiology of open tibia fractures in a population-based database: update on current risk factors and clinical implications. European journal of trauma and emergency surgery : official publication of the European Trauma Society. 2018 Feb 2 [PubMed PMID: 29396757] [6] Lovalekar M,Abt JP,Sell TC,Lephart SM,Pletcher E,Beals K, Accuracy of recall of musculoskeletal injuries in elite military personnel: a cross-sectional study. BMJ open. 2017 Dec 14 [PubMed PMID: 29247087] [7] Santos AL,Nitta CT,Boni G,Sanchez GT,Tamaoki MJS,Reis FBD, EVALUATION AND COMPARISON OF OPEN AND CLOSED TIBIA SHAFT FRACTURES IN A QUATERNARY REFERENCE CENTER. Acta ortopedica brasileira. 2018 May-Jun [PubMed PMID: 30038546] [8] Oliveira RV,Cruz LP,Matos MA, Comparative accuracy assessment of the Gustilo and Tscherne classification systems as predictors of infection in open fractures. Revista brasileira de ortopedia. 2018 May-Jun [PubMed PMID: 29892582] [9] M'Bra KI,Kouassi AAN,Sery BJLN,Yao LB,Kouassi KJE,Ochou PG Jr,Asséré YAGRA,Lohourou GF,Krah KL,Kodo M, [Secondary amputation of the limb after primary surgery of open fractures of the lower limb]. The Pan African medical journal. 2018 [PubMed PMID: 30050636]