Amp C

Detection of plasmid-mediated class C β -lactamases Doi Y, Paterson DL International Journal of Infectious Diseases (May 2007) 11, 191-197 Dr Preneshni R Naicker

Introduction ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

Class C β -lactamases ,[object Object],[object Object]

Table 1. Rationale for detection of plasmid-mediated class C β-lactamases ,[object Object],[object Object],[object Object],[object Object],[object Object]

Screening Tests for detection of plasmid-mediated class C beta-lactamases ,[object Object],[object Object],↓ susceptibility to expanded-spectrum cephalosporins but S Cefepime/Cefpirome ,[object Object],[object Object],↓ susceptibility to expanded-spectrum cephalosporins and lack of inhibition of β -lactamase inhibitors ,[object Object],[object Object],↓ susceptibility to expanded-spectrum cephalosporins and resistance to FOX Characteristics Tests

Confirmatory Tests for detection of plasmid-mediated class C beta-lactamases ,[object Object],[object Object],Multiplex PCR ,[object Object],Boronic acid disk test ,[object Object],[object Object],APB-based disk/microdilution test ,[object Object],AmpC disk test ,[object Object],[object Object],3D Test Characteristics Test

Inhibitor-based tests ,[object Object],[object Object],[object Object],[object Object],[object Object]

Genetic/Immunologic Tests ,[object Object],[object Object]

Amp C

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Amp C