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The Pharmaceutical Market: France
Published on April 2011

                                                                                                               Report Summary

Espicom's highly regarded world pharmaceutical market reports have been redesigned to provide enhanced strategic intelligence in a
user-friendly format. Each report provides in-depth information, setting the pharmaceutical market in context. The reports provide:



Five-year projections for economic, demographic, health expenditure, health workforce and pharmaceutical market indicators.
Specialised intelligence on OTCs, generics, biologics and biosimilars.
Exclusive economic and demographic data from the Economist Intelligence Unit (EIU) for each market in the series.
A separate statistical health file, comprising health expenditure, health infrastructure, health services and health personnel.
The reports are updated quarterly, providing you with the latest information for a full year. In addition, the service will keep you up to
date with market and industry news on a regular basis.




                                                                                                                Table of Content

Table of Contents



EXECUTIVE SUMMARY 1
Snapshot: Strategic Espicom Analysis 2
Snapshot: Key Data Projections                   3
MACROENVIRONMENT 4
POLITICAL 4
ECONOMIC5
LEGAL 6
EU Patent Protection 6
Proposal for Unitary Patent 6
Patent Settlements 6
EU Supplementary Protection Certificates 7
EU Data Exclusivity7
DEMOGRAPHIC                8
Projections 8
Demographic Indicators 9
Birth Rate 9
Death Rate           9
Infant Mortality 9
Life Expectancy at Birth 9
EPIDEMIOLOGY                   10
DISEASE BURDEN                  10
DISEASE PREVALENCE 10



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Communicable Diseases 10
Hepatitis C / Hepatitis B                10
HIV/AIDS 10
Non-communicable Diseases                      11
EU DIRECTIVE13
Cross-Border Healthcare Directive 13
ORGANISATION 13
National Health Agencies                 13
Regional Health Agencies                  14
Public Hospitals 14
Hospital Restructuring              14
Regional Health Organisation Plans (SROS)                       15
Ambulatory Services 16
Health Insurance System17
EXPENDITURE               18
Projections         18
Latest Figures 19
Pharmaceutical Expenditure 19
INFRASTRUCTURE/SERVICES 20
Public Hospitals 20
Private Hospitals 21
Non-Profitmaking Hospitals 21
Commercial Clinics 21
Regional chains 22
Inpatient Analysis23
Surgical Activity 25
Obstetric Activity 25
Diagnostic & Therapeutic Activity in the Private Sector              26


Ambulatory Activity 27
Home Hospitalisation                27
WORKFORCE 28
Projections         28
REGULATORY AFFAIRS                        30
EU REGULATION 30
EMA        30
Registration 30
Centralised Procedure 30
NATIONAL AUTHORITY 31
MARKETING AUTHORISATIONS                              31
POST-MARKETING SURVEILLANCE                                32
ADVERTISING32
PRICING & REIMBURSEMENT 33
EU NM CAPR 33
PRICING         33
Pricing Of Reimbursable Medicines in the Retail Pharmacy Sector 33
Price Revisions           34
Pricing Activity         35
State-Industry Framework Agreements                        36
Pharmacy Margins               37


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Reference Pricing (TFR) 37
Pricing of Hospital Medicines                37
REIMBURSEMENT                    38
Social Security Pharmaceutical Reimbursement Spending Trends 39
DISTRIBUTION CHANNELS                       40
WHOLESALING 40
Distributors          40
Alliance Healthcare40
CERP 40
OCP         40
Phoenix Pharma                  41
RETAILING41
MARKET ANALYSIS 42
SIZE        42
Projections           42
Historical Figures 44
Current Structure 45
PRODUCT DEVELOPMENT 47
EU IMI 47
National Product Development 47
LEEM-Recherche                  47
Ipsen 49
Pierre Fabre 50
sanofi-aventis             50
Servier      50
MANUFACTURING                    51
Domestic Production51
TRADE53
Exports          53
Imports          56
Balance of Trade 59
COMPETITION 60
TRADE ASSOCIATIONS 60
LEEM / LEEM Recherche 60
LIR 60
COMPANY INTELLIGENCE 61
Local Manufacturers 61
Ipsen 61
Pierre Fabre 62
sanofi-aventis             63
Servier      64
Multinational Manufacturers                64
AstraZeneca64
Bristol-Myers Squibb 65
Eli Lilly        65
GSK         65
MSD 65
Pfizer 65
Competitive Strategies 66
OTC PHARMACEUTICALS 67


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MARKET SIZE 67
GENERIC PHARMACEUTICALS                               69
REGULATION 69
EU Marketing Registration 69
MARKET SIZE 69
COMPETITION               72
Trade Association72
GEMME 72
BIOLOGICS & BIOSIMILARS                      73
REGULATION 73
EU Approval Process 73
EU Regulation of Biosimilars                 73
EMA Guideline Documents 74
Biosimilar mAb Guideline 74
COMPETITION               74
Trade Associations              74
Atlantic Biotherapies           74
Eurobiomed 74
France Biotech 75
Company Intelligence              75
AB Science           75
Carmat         75
Cellectis 75
Cerenis Therapeutics             75
ExonHit Therapeutics 75
Genethon            75
Genfit 76
GenOway             76
Hybrigenics 76
Innate Pharma 76
Ipsogen 76


LFB       77
Neovacs 77
NicOx77
Sanofi Pasteur 78
Stallergenes 78
Transgene           78
Vivalis      79
Competitive Strategies 79
CONCLUSIONS: OPPORTUNITIES & CHALLENGES                    80
Strategic Espicom Analysis 80
MACROENVIRONMENT                       80
EPIDEMIOLOGY               80
HEALTHCARE 81
REGULATORY AFFAIRS                      81
PRICING & REIMBURSEMENT82
DISTRIBUTION CHANNELS                       82
MARKET          82
COMPETITION 83


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OTC PHARMACEUTICALS 83
GENERIC PHARMACEUTICALS                             83
BIOLOGICS & BIOSIMILARS 83
Radar Analysis          85
SWOT Analysis            85
DIRECTORY 86
GOVERNMENT ORGANISATIONS 86
PRODUCERS 86
Local Producers 86
Multinational Producers 86
Biologic Producers            86
TRADE ASSOCIATIONS 87



List of Tables
Espicom Analysis of the Pharmaceutical Market, 2011                    2
Key Data Projections, 2011-2016                  3
Political Landscape, 2011 4
Regional Ranking of Projected Economies, 2016 5
Projected Economy, 2011-2016                     5
Regional Ranking of Projected Demographics, 2016 8
Projected Demographics, 2011-2016 8
Principal Demographic Indicators, 2000-2009                   9
New Cases of Long-Term Illnesses, 2004-2008                       11
Projected Patients Registered with Long-Term Illnesses, Régime Génerale, 2008/2011/2015 12
Regional Ranking of Projected Health Expenditure, 2016                     18
Projected Health Expenditure, 2011-2016                  18
Health Expenditure, 2002-2009 19
Pharmaceutical Expenditure, 2000-2009 (Million Euros)                  19
Pharmaceutical Expenditure by Source of Funding, 2003-2009 (%) 19
Summary of Hospitals & Beds                    20
Hospital Activity, 2005-2009 23
Hospital Activity by Specialty, 2009 23
Hospital Activity in Short-Stay Units, 2009              24
Diagnostic and Therapeutic Procedures Performed in Public and Private Hospitals, 2009 25
Regional Ranking of Projected Physicians, 2016 28
Projected Physicians, 2011-2016 28
Medical Personnel, 2005-2010                  29
MA Activity, 2000-2009 31
Drug Pricing Applications Submitted by Type, 2008 35
Average Number of Days Taken to Process First-Time Registrations, 2008 35
Taxes and Other Financial Contributions Imposed on Pharmaceutical Companies, 2000-2007 (Million Euros) 36
Distribution of the Pharmaceutical Market According to Reimbursement Rate, 2007-2008 39
Social Security Drug Reimbursement, 2003-2006 (Million Euros)                        39
Active Pharmacies According to Legal Status, 2001 41
Regional Ranking of Projected Pharmaceutical Markets at Retail Prices, 2016 42
Projected Pharmaceutical Market at Retail Prices, 2011-2016                     42
Historical Pharmaceutical Market at Retail Prices, 1995-2010 44
Pharmaceutical Sales at Manufacturers' Prices, 2000-2009 (Million Euros) 45
Pharmaceutical Sales at Manufacturers' Prices, 2000-2009 (%)                     46


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Change in Pharmaceutical Sales at Manufacturers' Prices, 2001-2009 (%)46
Pharmaceutical Industry R&D Expenditure, 1995-2006 49
Trends in Pharmaceutical Manufacturing Industry, 2000-2006 51
Pharmaceutical Manufacturing Industry by Principal Sector, 2006 51
Production of Medicaments and Vaccines for Human Use, 2004-2007 (Million Euros) 52
Pharmaceutical Exports by Category, 2004-2008 (US$ Millions)              53
Exports of Raw Materials by Country/Region, 2008 (US$000s) 54
Exports of Antisera & Vaccines by Country/Region, 2008 (US$000s)               55
Exports of Medicaments by Country/Region, 2008 (US$000s)             55
Pharmaceutical Imports by Category, 2004-2008 (US$ Millions)              56
Imports of Raw Materials by Country/Region, 2008 (US$000s) 57
Imports of Antisera & Vaccines by Country/Region, 2008 (US$000s)               58
Imports of Medicaments by Country/Region, 2008 (US$000s) 58
Balance of Pharmaceutical Trade, 2004-2008 (US$000s)            59
Members of LEEM Recherche, 2007 60
Members of LIR, 201060
sanofi-aventis' Top 10 Pharmaceutical Products by Sales, First Half 2009-2010 (Million Euros) 63
Generic Sales Value & Volume in Reimbursable Pharmacy Sector at Manufacturers' Prices, 2000-2009 (%)69
Generic Sales Value in Reimbursable Pharmacy Sector at Manufacturers' Prices, 2000-2009 70
Members of GEMME, 2010                    72
Sanofi Pasteur's Sales by Vaccine Type, First Half 2009-2010 (Million Euros)              78
Espicom Analysis of the Pharmaceutical Market, 2011 84
SWOT Analysis of the Pharmaceutical Market, 2011 85



List of Charts
Regional Comparison of Top-5 Projected Pharmaceutical Markets at Retail Prices, 2016 42
Regional Comparison of Projected Pharmaceutical Market Share, 2016                  43
Historical Pharmaceutical Market at Retail Prices, 1995-2010         45
R&D Employment within the French Pharmaceutical Industry, 1995-2005 (%)48
Clinical Trials Initiated, 1995-2006 (%)              49
Pharmaceutical Exports, 1999-2008 53
Leading Destinations of Pharmaceuticals, 2008 (%) 54
Pharmaceutical Imports, 1999-2008 56
Pharmaceutical Imports by Country/Region, 2008 (%) 57
Pharmaceutical Balance of Trade, 1999-2007 (US$ Billions) 59
Distribution of the OTC Pharmaceutical Market by Product Status, 2008 (%)                67
Radar Graph of the Pharmaceutical Market, 2011             85




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The Pharmaceutical Market: France

  • 1. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! The Pharmaceutical Market: France Published on April 2011 Report Summary Espicom's highly regarded world pharmaceutical market reports have been redesigned to provide enhanced strategic intelligence in a user-friendly format. Each report provides in-depth information, setting the pharmaceutical market in context. The reports provide: Five-year projections for economic, demographic, health expenditure, health workforce and pharmaceutical market indicators. Specialised intelligence on OTCs, generics, biologics and biosimilars. Exclusive economic and demographic data from the Economist Intelligence Unit (EIU) for each market in the series. A separate statistical health file, comprising health expenditure, health infrastructure, health services and health personnel. The reports are updated quarterly, providing you with the latest information for a full year. In addition, the service will keep you up to date with market and industry news on a regular basis. Table of Content Table of Contents EXECUTIVE SUMMARY 1 Snapshot: Strategic Espicom Analysis 2 Snapshot: Key Data Projections 3 MACROENVIRONMENT 4 POLITICAL 4 ECONOMIC5 LEGAL 6 EU Patent Protection 6 Proposal for Unitary Patent 6 Patent Settlements 6 EU Supplementary Protection Certificates 7 EU Data Exclusivity7 DEMOGRAPHIC 8 Projections 8 Demographic Indicators 9 Birth Rate 9 Death Rate 9 Infant Mortality 9 Life Expectancy at Birth 9 EPIDEMIOLOGY 10 DISEASE BURDEN 10 DISEASE PREVALENCE 10 The Pharmaceutical Market: France (From Slideshare) Page 1/8
  • 2. Find Industry reports, Company profiles ReportLinker and Market Statistics Communicable Diseases 10 Hepatitis C / Hepatitis B 10 HIV/AIDS 10 Non-communicable Diseases 11 EU DIRECTIVE13 Cross-Border Healthcare Directive 13 ORGANISATION 13 National Health Agencies 13 Regional Health Agencies 14 Public Hospitals 14 Hospital Restructuring 14 Regional Health Organisation Plans (SROS) 15 Ambulatory Services 16 Health Insurance System17 EXPENDITURE 18 Projections 18 Latest Figures 19 Pharmaceutical Expenditure 19 INFRASTRUCTURE/SERVICES 20 Public Hospitals 20 Private Hospitals 21 Non-Profitmaking Hospitals 21 Commercial Clinics 21 Regional chains 22 Inpatient Analysis23 Surgical Activity 25 Obstetric Activity 25 Diagnostic & Therapeutic Activity in the Private Sector 26 Ambulatory Activity 27 Home Hospitalisation 27 WORKFORCE 28 Projections 28 REGULATORY AFFAIRS 30 EU REGULATION 30 EMA 30 Registration 30 Centralised Procedure 30 NATIONAL AUTHORITY 31 MARKETING AUTHORISATIONS 31 POST-MARKETING SURVEILLANCE 32 ADVERTISING32 PRICING & REIMBURSEMENT 33 EU NM CAPR 33 PRICING 33 Pricing Of Reimbursable Medicines in the Retail Pharmacy Sector 33 Price Revisions 34 Pricing Activity 35 State-Industry Framework Agreements 36 Pharmacy Margins 37 The Pharmaceutical Market: France (From Slideshare) Page 2/8
  • 3. Find Industry reports, Company profiles ReportLinker and Market Statistics Reference Pricing (TFR) 37 Pricing of Hospital Medicines 37 REIMBURSEMENT 38 Social Security Pharmaceutical Reimbursement Spending Trends 39 DISTRIBUTION CHANNELS 40 WHOLESALING 40 Distributors 40 Alliance Healthcare40 CERP 40 OCP 40 Phoenix Pharma 41 RETAILING41 MARKET ANALYSIS 42 SIZE 42 Projections 42 Historical Figures 44 Current Structure 45 PRODUCT DEVELOPMENT 47 EU IMI 47 National Product Development 47 LEEM-Recherche 47 Ipsen 49 Pierre Fabre 50 sanofi-aventis 50 Servier 50 MANUFACTURING 51 Domestic Production51 TRADE53 Exports 53 Imports 56 Balance of Trade 59 COMPETITION 60 TRADE ASSOCIATIONS 60 LEEM / LEEM Recherche 60 LIR 60 COMPANY INTELLIGENCE 61 Local Manufacturers 61 Ipsen 61 Pierre Fabre 62 sanofi-aventis 63 Servier 64 Multinational Manufacturers 64 AstraZeneca64 Bristol-Myers Squibb 65 Eli Lilly 65 GSK 65 MSD 65 Pfizer 65 Competitive Strategies 66 OTC PHARMACEUTICALS 67 The Pharmaceutical Market: France (From Slideshare) Page 3/8
  • 4. Find Industry reports, Company profiles ReportLinker and Market Statistics MARKET SIZE 67 GENERIC PHARMACEUTICALS 69 REGULATION 69 EU Marketing Registration 69 MARKET SIZE 69 COMPETITION 72 Trade Association72 GEMME 72 BIOLOGICS & BIOSIMILARS 73 REGULATION 73 EU Approval Process 73 EU Regulation of Biosimilars 73 EMA Guideline Documents 74 Biosimilar mAb Guideline 74 COMPETITION 74 Trade Associations 74 Atlantic Biotherapies 74 Eurobiomed 74 France Biotech 75 Company Intelligence 75 AB Science 75 Carmat 75 Cellectis 75 Cerenis Therapeutics 75 ExonHit Therapeutics 75 Genethon 75 Genfit 76 GenOway 76 Hybrigenics 76 Innate Pharma 76 Ipsogen 76 LFB 77 Neovacs 77 NicOx77 Sanofi Pasteur 78 Stallergenes 78 Transgene 78 Vivalis 79 Competitive Strategies 79 CONCLUSIONS: OPPORTUNITIES & CHALLENGES 80 Strategic Espicom Analysis 80 MACROENVIRONMENT 80 EPIDEMIOLOGY 80 HEALTHCARE 81 REGULATORY AFFAIRS 81 PRICING & REIMBURSEMENT82 DISTRIBUTION CHANNELS 82 MARKET 82 COMPETITION 83 The Pharmaceutical Market: France (From Slideshare) Page 4/8
  • 5. Find Industry reports, Company profiles ReportLinker and Market Statistics OTC PHARMACEUTICALS 83 GENERIC PHARMACEUTICALS 83 BIOLOGICS & BIOSIMILARS 83 Radar Analysis 85 SWOT Analysis 85 DIRECTORY 86 GOVERNMENT ORGANISATIONS 86 PRODUCERS 86 Local Producers 86 Multinational Producers 86 Biologic Producers 86 TRADE ASSOCIATIONS 87 List of Tables Espicom Analysis of the Pharmaceutical Market, 2011 2 Key Data Projections, 2011-2016 3 Political Landscape, 2011 4 Regional Ranking of Projected Economies, 2016 5 Projected Economy, 2011-2016 5 Regional Ranking of Projected Demographics, 2016 8 Projected Demographics, 2011-2016 8 Principal Demographic Indicators, 2000-2009 9 New Cases of Long-Term Illnesses, 2004-2008 11 Projected Patients Registered with Long-Term Illnesses, Régime Génerale, 2008/2011/2015 12 Regional Ranking of Projected Health Expenditure, 2016 18 Projected Health Expenditure, 2011-2016 18 Health Expenditure, 2002-2009 19 Pharmaceutical Expenditure, 2000-2009 (Million Euros) 19 Pharmaceutical Expenditure by Source of Funding, 2003-2009 (%) 19 Summary of Hospitals & Beds 20 Hospital Activity, 2005-2009 23 Hospital Activity by Specialty, 2009 23 Hospital Activity in Short-Stay Units, 2009 24 Diagnostic and Therapeutic Procedures Performed in Public and Private Hospitals, 2009 25 Regional Ranking of Projected Physicians, 2016 28 Projected Physicians, 2011-2016 28 Medical Personnel, 2005-2010 29 MA Activity, 2000-2009 31 Drug Pricing Applications Submitted by Type, 2008 35 Average Number of Days Taken to Process First-Time Registrations, 2008 35 Taxes and Other Financial Contributions Imposed on Pharmaceutical Companies, 2000-2007 (Million Euros) 36 Distribution of the Pharmaceutical Market According to Reimbursement Rate, 2007-2008 39 Social Security Drug Reimbursement, 2003-2006 (Million Euros) 39 Active Pharmacies According to Legal Status, 2001 41 Regional Ranking of Projected Pharmaceutical Markets at Retail Prices, 2016 42 Projected Pharmaceutical Market at Retail Prices, 2011-2016 42 Historical Pharmaceutical Market at Retail Prices, 1995-2010 44 Pharmaceutical Sales at Manufacturers' Prices, 2000-2009 (Million Euros) 45 Pharmaceutical Sales at Manufacturers' Prices, 2000-2009 (%) 46 The Pharmaceutical Market: France (From Slideshare) Page 5/8
  • 6. Find Industry reports, Company profiles ReportLinker and Market Statistics Change in Pharmaceutical Sales at Manufacturers' Prices, 2001-2009 (%)46 Pharmaceutical Industry R&D Expenditure, 1995-2006 49 Trends in Pharmaceutical Manufacturing Industry, 2000-2006 51 Pharmaceutical Manufacturing Industry by Principal Sector, 2006 51 Production of Medicaments and Vaccines for Human Use, 2004-2007 (Million Euros) 52 Pharmaceutical Exports by Category, 2004-2008 (US$ Millions) 53 Exports of Raw Materials by Country/Region, 2008 (US$000s) 54 Exports of Antisera & Vaccines by Country/Region, 2008 (US$000s) 55 Exports of Medicaments by Country/Region, 2008 (US$000s) 55 Pharmaceutical Imports by Category, 2004-2008 (US$ Millions) 56 Imports of Raw Materials by Country/Region, 2008 (US$000s) 57 Imports of Antisera & Vaccines by Country/Region, 2008 (US$000s) 58 Imports of Medicaments by Country/Region, 2008 (US$000s) 58 Balance of Pharmaceutical Trade, 2004-2008 (US$000s) 59 Members of LEEM Recherche, 2007 60 Members of LIR, 201060 sanofi-aventis' Top 10 Pharmaceutical Products by Sales, First Half 2009-2010 (Million Euros) 63 Generic Sales Value & Volume in Reimbursable Pharmacy Sector at Manufacturers' Prices, 2000-2009 (%)69 Generic Sales Value in Reimbursable Pharmacy Sector at Manufacturers' Prices, 2000-2009 70 Members of GEMME, 2010 72 Sanofi Pasteur's Sales by Vaccine Type, First Half 2009-2010 (Million Euros) 78 Espicom Analysis of the Pharmaceutical Market, 2011 84 SWOT Analysis of the Pharmaceutical Market, 2011 85 List of Charts Regional Comparison of Top-5 Projected Pharmaceutical Markets at Retail Prices, 2016 42 Regional Comparison of Projected Pharmaceutical Market Share, 2016 43 Historical Pharmaceutical Market at Retail Prices, 1995-2010 45 R&D Employment within the French Pharmaceutical Industry, 1995-2005 (%)48 Clinical Trials Initiated, 1995-2006 (%) 49 Pharmaceutical Exports, 1999-2008 53 Leading Destinations of Pharmaceuticals, 2008 (%) 54 Pharmaceutical Imports, 1999-2008 56 Pharmaceutical Imports by Country/Region, 2008 (%) 57 Pharmaceutical Balance of Trade, 1999-2007 (US$ Billions) 59 Distribution of the OTC Pharmaceutical Market by Product Status, 2008 (%) 67 Radar Graph of the Pharmaceutical Market, 2011 85 The Pharmaceutical Market: France (From Slideshare) Page 6/8
  • 7. Find Industry reports, Company profiles ReportLinker and Market Statistics Fax Order Form To place an order via fax simply print this form, fill in the information below and fax the completed form to: Europe, Middle East and Africa : + 33 4 37 37 15 56 Asia, Oceania and America : + 1 (805) 617 17 93 If you have any questions please visit http://www.reportlinker.com/notify/contact Order Information Please verify that the product information is correct and select the format(s) you require. The Pharmaceutical Market: France Product Formats Please select the product formats and the quantity you require. 1 User License--USD 1 041.25 Quantity: _____ Contact Information Please enter all the information below in BLOCK CAPITALS Title: Mr Mrs Dr Miss Ms Prof First Name: _____________________________ Last Name: __________________________________ Email Address: __________________________________________________________________________ Job Title: __________________________________________________________________________ Organization: __________________________________________________________________________ Address: __________________________________________________________________________ City: __________________________________________________________________________ Postal / Zip Code: __________________________________________________________________________ Country: __________________________________________________________________________ Phone Number: __________________________________________________________________________ Fax Number: __________________________________________________________________________ The Pharmaceutical Market: France (From Slideshare) Page 7/8
  • 8. Find Industry reports, Company profiles ReportLinker and Market Statistics Payment Information Please indicate the payment method, you would like to use by selecting the appropriate box. Payment by credit card Card Number: ______________________________________________ Expiry Date __________ / _________ CVV Number _____________________ Card Type (ex: Visa, Amex…) _________________________________ Payment by wire transfer Crédit Mutuel RIB : 10278 07314 00020257701 89 BIC : CMCIFR2A IBAN : FR76 1027 8073 1400 0202 5770 189 Payment by check UBIQUICK SAS 16 rue Grenette – 69002 LYON, FRANCE Customer signature:   Please note that by ordering from Reportlinker you are agreeing to our Terms and Conditions at http://www.reportlinker.com/index/terms Please fax this form to: Europe, Middle East and Africa : + 33 4 37 37 15 56 Asia, Oceania and America : + 1 (805) 617 17 93 The Pharmaceutical Market: France (From Slideshare) Page 8/8