1. Curriculum Vitae
Ryan D. Russell, Ph.D.
BUSINESS ADDRESS
Menzies Institute for Medical Research
Muscle Metabolism and Diabetes Research Group
23, Hobart TAS 7000
RyanRussellPhD@gmail.com
R.Russell@utas.edu.au
www.facebook.com/MenziesFit
EDUCATION
2002 B.S. Major: Biomedical Science; Minor: English Literature, Marquette
University, Milwaukee, WI
2011 Ph.D. Kinesiology, Louisiana State University, Baton Rouge, LA
Thesis: An Examination of Metabolism in Diabetic Offspring
Committee Members:
Arnold Nelson, Ph.D. (Chair) Robert R Kraemer, Ed.D.
Jan Hondzinski, Ph.D. T. Gilmour Reeve, Ph.D.
Matthew Hulver, Ph.D.
APPOINTMENTS
POST-GRADUATE TRAINING
Sept 2014 – Present
2014 ACSM Visiting Scholar and Junior Research Fellow, Menzies Institute for Medical Research,
Muscle Metabolism and Diabetes Research Group
 Coordinate and run multiple patient-oriented clinical trials and exercise interventions aimed at improving
microvascular blood flow and symptoms of type 2 diabetes.
 Extensive experience in grant-writing, contrast-enhanced ultrasound (CEU) with microbubbles, Laser-
Dopper flow, manuscript writing, Mobile-O-Graph PWA, indirect calorimetry.
Sept 2013 – Aug 2014
Postdoctoral Fellow, UCLA School of Nursing
Large-scale, NIH-funded patient-oriented resistance-training intervention (Get Fit Study)
 Limited experience in endothelial progenitor cell (EPC) principals and applications, brachial artery flow-
mediated dilation testing and analysis, pulse wave analysis (PWA) and pulse wave velocity (PWV) testing
and analysis.
 Experience in Cell-signaling and molecular aspects of oxidized HDL-stimulated ET-1 synthesis and
secretion, primary endothelial cell project: dose-response of nicotine on ROS production in EC, ELISA,
Western Blot, and other previously acquired basic science techniques.
 Extensive experience in Continuous 24-hour glucose monitoring systems (CGMS), oxygen kinetics and
metabolic flexibility during and after exercise, large database design and management.
August 2011 – August 2013
NIH/NHLBI T32 HL072751-07 Training Grant in Cardiac and Vascular Cell Biology, University of
Maryland, School of Medicine
 Training in molecular and cellular biology under guidance of Michael Quon and Xiao Jian Sun.
 Limited experience in mouse/rodent (mouse and rat) handling, GTT, injections, euthanizing, etc.

2.  Experience in Q RT-PCR, Real Time PCR, microscopy, Transformations, primer design, RNA isolation,
grant- writing, scrambled/siRNA, and molecular biology techniques.
 Extensive experience in: Western Blot, cell culture, transient transfections, mini and maxi-prep,
experimental cell-culture design, luciferase testing, cell freezing and thawing, cDNA preparation, DNA
cutting, RNA, DNA and protein concentration using nano-drop, making agarose and acrylamide gels for
DNA testing and Western Blot and subsequent analysis, making basic lab solutions for routine use, and
general cellular techniques including various cell lines and primary endothelial cells.
April 2011- May 2011
Visiting Scholar, Virginia Tech
 Experience in Nano-dropping, DNA, RNA and protein Isolations, RT-PCR and Western Blots, and
assisted in animal procedures/care under Matthew Hulver.
DOCTORAL AND PRE-DOCTORAL
Sept 2010- Dec 2010
Visiting Scholar, M3 Lab, Maastricht University, Netherlands
 Continuous 24 hour glucose monitoring system (CGMS) under Prof. Luc van Loon
 Compared GlucoDay with MiniMed CGMS systems
 Compared CGMS changes with varying exercise frequency and duration
 Training in Metabolic Flexibility assessment, and study design
 Accessioning and snap-freezing plasma
June-July 2010
Lab Volunteer, Pennington Biomedical Research Center (PBRC), Clinical and Accessioning.
 Shadowed and observed laboratory methods in Accessioning and Clinical Chemistry laboratories of the
PBRC.
2009-2011
PhD Student, Department of Kinesiology, Louisiana State University
 Coordinated resting metabolism and oxidative stress study in diabetics, diabetic offspring, and healthy
controls
 Quantified RMR, RER and metabolic flexibility in relation to fasting, stretching, and during OGTT
Examined blood/plasma markers of oxidative stress in diabetics, diabetic offspring and controls;
established a metabolic profile for diabetic offspring vs those with no history of diabetes.
 Classes taught to undergraduates: Anatomy lab (computer based), Exercise physiology lab (hands on),
circuit and resistance training (hands on).
2004-2009
Research Associate, Department of Kinesiology, Louisiana State University
 Conducted Continuous Scale Physical Function and Performance (CSPFP-10) tests at Leo S Butler Center,
Saint James Place, and Pennington Biomedical Research Center.
 Utilized K-4 portable metabolic testing unit in various elderly populations at Saint James Place, Leo S
Butler Center, and Pennington Biomedical Research Center for Continuous Scale Physical Function and
Performance (CSPFP-10) and treadmill tests.
 Conducted ultra-high resolution ultrasound for assessing brachial artery indices in young athletes, obese
volunteers, and elderly research participants (age 18-102)
 Analyzed ultrasound images with specialized semi-automated edge-detecting software.
2002-2004

3. Research Associate, Pennington Biomedical Research Center (PBRC)
 Performed MRS analysis in muscle and liver.
 Conducted research and development activities to augment knowledge of mechanisms of obesity and age
related illnesses.
 Evaluated and analyzed clinical research data. Utilized computer networking to do research with
individual’s offsite.
 Conducted exercise testing (VO2max tests, stress tests, YMCA Bike tests, Cybex tests, endurance
performance tests, pulmonary function, and 12-Lead EKG), assigned exercise prescriptions for
participants, scheduling, scientific paper writing, and research in Pennington’s Fitness Center.
 Supervised an exercise lab at LSU for a new Wellness Program.
 Used IDEEA from MiniSun to monitor participant’s activities, and train researchers on how to use this
accelerometer.
 Performed all MRI muscle analysis for PBRC.
 Compared energy expenditure from both doubly labeled water and accelerometers from the CALERIE
study.
 Communicated findings through reports and publications, monitor and report on progress of ongoing
clinical studies. Recruited and screened research patients. Conducted patient interviews to evaluate patient
eligibility for studies coordinated.
 Managed large databases for data collected from studies, and delegated tasks to others.
HONORS AND AWARDS
Christian Brothers University
Cross Country Letterman. 1997 – 1998
Marquette University
Men’s Lightweight Crew Team Letterman. 2000 – 2001
Louisiana State University, Dept. of Kinesiology,
Lillian Olsen scholarship recipient. 2006 – 2010
Louisiana State University, Dept. of Kinesiology,
National Institute on Aging (P01 AG022064) research fellowship
(Louisiana Healthy Aging Study). 2004 – 2009
Louisiana State University, Dept. of Kinesiology PhD Program,
Board of Supervisors Scholarship. 2010 – 2011
Louisiana State University, Dept. of Kinesiology,
Lifestyle and Aging research endowment. 2005 – 2010
American College of Sports Medicine 2014 Visiting Scholar Award. 2014 – 2015
EXTRAMURAL GRANT SUPPORT
ACTIVE
1) American College of Sports Medicine (ACSM) Visiting Scholar Award:
Microvascular-linked Metabolic Flexibility in Adult Offspring of Type-2
Diabetics.
Menzies Research Institute, Tasmania, Australia.

4. Purpose: Gain cutting-edge, highly sought-after vascular and cardiac imaging skills,
Trained by Drs. Marwick, Rattigan, Sharman, and Keske.
September 2014 – May 2015
PI $5,000
2) virtual Tasmanian Academic Health Science Precinct (vTAHSP) Grant.
Cardiometabolic benefits of exercise training in type 2 diabetics independent of
weight loss.
Sept. 2014 – May 2015
Co-Investigator $50,734
3) Royal Hobart Hospital (RHH) Research Foundation Grant
Pilot Grant: Microvascular dysfunction in adult offspring of type 2 diabetics
Menzies Research Institute; Royal Hobart Hospital, Tasmania, Australia.
August 2014 – July 2015
Co-Investigator $20,294
4) Menzies Research Institute Tasmania top-up funds.
2014 – 2015
Co-Investigator $35,000
COMPLETED
1) NIH/NHLBI T32 HL072751-07 Training Grant in Cardiac and Vascular
Cell Biology, 2011 - 2013 $102,000
2) NIMHD Health Disparities, NIH-Loan Repayment Program (LRP) recipient.
2012 - 2014 $43,000
PENDING
1) National Health and Medical Research Council (NHMRC)
Preventing T2D by Targeting Microvascular Blood Flow in Offspring of T2D patients.
Scope: Utilize resistance exercise and traditional pharmaceutical therapies to target
microvascular blood flow in at-risk populations.
Jan 2016 – Dec 2020
Co-I $1,570,000
2) Cancer Australia.
Novel Therapy to Improve Smoking Cessation, Weight Maintenance, and Cardiometabolic Health.
Scope: To improve smoking cessation and decrease cancer risk profiles by
using resistance training in combination with NRT.
Jan 2016 – Dec 2018
CI-A (PI) $505,540
3) Diabetes Australia
Cardiometabolic response of exercise in overweight/obese patients with type 2 diabetes & pre-diabetes
Scope: Identify early CMS markers of T2D in response to exercise training in people
with T2D.
Jan 2016 – Dec 2016
Co-I
$60,000

5. 4) Diabetes Australia
Impact of family history of T2D on post-contraction muscle blood flow, metabolic flexibility, and
Continuous 24-hour glucoregulation (CGMS).
Scope: Identify microvascular mechanisms regulation post-exercise substrate oxidation and continuous
glucoregulatory function over 3 days in diabetics with and without a family history of T2D.
Jan 2016 – Dec 2016
PI $60,000
PROFESSIONAL SOCIETIES
The American College of Sports Medicine (2004 – present)
Mid-Atlantic Regional Conference- American College of Sports Medicine (2012 – 2014)
American Diabetes Association (2012 – present)
American Heart Association (2013 – present)
TEACHING SERVICE
Louisiana State University
Sept 2004- July 2010
Guest Lecturer: Exercise Physiology
Presented guest lectures on cardiovascular function, VO2, metabolic function and cardiometabolic syndrome.
Incorporated the STAR (Science Teacher And Researcher) teaching techniques, with heavy emphasis on
student interactions and responses.
Guest Lecturer: Exercise in Health and Disease lectures
Presented guest lectures on exercise in response to diabetes and cardiovascular disease, as well as exercise
prescription in aging populations.
Incorporated the STAR (Science Teacher And Researcher) teaching techniques, with heavy emphasis on
student interactions and responses.
Exercise Physiology Lab (2004 – 2006)
Lectured prior to each lab discussing the practical and physiologic applications of each set of tests. Taught
principals of testing, and testing methods for various clinical exercise physiology tests, including VO2 max,
cycle ergometer, plyometric jump, etc.
Student Reviews: 4.8 (out of 5)
Anatomy Lab (2006 – 2008, 2010)
Taught computer-based interactive human anatomy using A.D.A.M. dissectible interactive software.
Created and graded online teaching and testing for anatomy using Blackboard.
Student Reviews: 4.5 (out of 5)
Circuit Training (2009 – 2010)
Developed a novel high intensity style resistance training (HIRST) circuit training program aimed at a full-
body workout in 10-minutes (Russell, RD,. JSCR. Oct 2014).
Student Reviews: 5 (out of 5)
Tutor for the LSU Center for Student-Athletes (2006-2008)
Lead group tutoring session, as well as one-on-one tutoring for LSU student athletes in various Kinesiology-
related courses.

6. Mentored two junior graduate students in both cardiovascular disease research, and etiology and progression
of diabetes and lipotoxicity. Both of whom are now tenure-track faculty at graduate institutions.
2015 – University of Tasmania
Coordinate 2 units (Genetics and Epidemiology) at the University of Tasmania. Responsibilities include
course development, syllabus design, coordination of lecture rooms and various lecturers, and grading.
PEER-REVIEWED PUBLICATIONS
1) Russell, R.D., Redmann, S.M., Ravussin, E., Hunter, G.R., Larson-Meyer, D.E.: Reproducibility of endurance
performance on a treadmill using a preloaded time trial. Med Sci Sports Exerc. 36:717-724, 2004.
2) Frisard, M.I., Fabre, J.M., Russell, R.D., King, C.M., DeLany, J.P., Wood, R.H., Ravussin, E.; for the
Louisiana Healthy Aging Study: Physical activity level and physical functionality in nonagenarians compared
to individuals aged 60-74 years. J Gerontol A Biol Sci Med Sci. 62:783-788, 2007. PMCID: PMC2724866.
3) Larson-Meyer, D.E., Borkhsenious, O.N., Gullett, J.C., Russell, R.D., Devries, M.C., Smith, S.R., Ravussin,
E.: Effect of dietary fat on serum and intramyocellular lipids and running performance. Med Sci Sports Exerc.
40:892-902, 2008. PMCID: PMC3182469.
4) Russell, R.D., Willis, K.S., Ravussin, E., Larson-Meyer E.D.: Effects of endurance running and dietary fat on
circulating ghrelin and peptide YY. J Sports Sci Med. 8:574-583, 2009. PMCID: PMC3172724.
5) Russell, R.D., Nelson, A.G., Kraemer, R.R.: Metabolic dysfunction in diabetic offspring: deviations in
metabolic flexibility. Med Sci Sports Exerc. 45(1):8-15, 2013. PMID: 22811035.
6) Zheng Y., Zhang L., Zeng Y., Fu M., Zhang D., Russell R.D.: Variants of NLRP3 gene are associated with
insulin resistance in Chinese type-2 diabetic patients. Gene. 1;530(1):151-4, 2013. PMID: 23973723.
7) Russell, R.D., Nelson, A.G., Kraemer, R.R.: Short bouts of high-intensity resistance-style training produce
similar reductions in fasting blood glucose of diabetic offspring and controls. J of Strength and Cond
Research. Oct;28(10):2760-7, 2014. PMID: 25051004.
8) Zheng, Y., Russell, R.D., Zhang, D. Circulating zonulin levels in newly diagnosed Chinese type 2 diabetes
patients. Diabetes Research and Clinical Practice. Dec 5(106):312-318, 2014. PMID: 25238913.
9) Zheng, D., Zhang, L., Yue, F., Zheng, Y., Russell, RD. Serum zonulin is elevated in women with polycystic
ovary syndrome, and correlates with insulin resistance and severity of anovulation. European Journal of
Endocrinology. 172:29-36, Jan 1, 2015. PMID: 25336505.
10) Zhang, L., Zhang, D., Zheng, Y., Hu, H., Zeng, Y., Yue, F., Russell, R.D. Association of NLRP3 gene variants
with metabolic syndrome in Chinese Han population. Pending review.
MANUSCRIPTS IN PROGRESS
Russell, R.D., Kraemer, R.R., Wong, K., McMillan R.P., Davis G.R., Van Dijk J.W., Keske, M.A., Kheterpal I.,
Nelson A.G., Roberts, C.K., Hulver M.W.: Changes in Lipotoxicity and Cardiovascular Disease Markers in
Diabetic Offspring and Controls with Resistance Training.
Russell, R.D., Premilovac, D., Rattigan, S., Keske, M.A.: Microvascular-linked metabolic inflexibility in adult
offspring of type-2 diabetics.

7. Russell, R.D., Davis, G., Richards, S.M., Kraemer, R.R., Keske, M.A.: Influence of Exercise on Oxidative Stress
in Resting Glucoregulatory Function with Insulin Resistance and Type 2 Diabetes. Invited book chapter – Glucose
Uptake.
Russell, R.D., Blackwood, S.J., Rattigan, S., Keske, M.A.: Muscular and Cutaneous Microvascular Blood Flow
in Forearm: Correlation between Contrast-Enhanced Ultrasound and Laser Doppler-Flow.
Blackwood, S.J., Russell, R.D., Rattigan, S., Keske, M.A.: Relationship between Muscular Strength, Bone
Density, and Cutaneous Microvascular Flux.
ABSTRACTS/PRESENTATIONS
1) Larson-Meyer, D.E., Frisard, M.I., Heilbronn, L.K., Newcomer, B.R., Russell, R.D., Ravussin, E., and The
Pennington CALERIE Group: Effect of 6-month calorie restriction and exercise on muscle and liver lipid in
relation to insulin sensitivity. Obes Res 12 (Supplement):A5, 2004. (oral presentation)
2) Moreira, E.A., Heilbronn, L.K., Russell, R.D., DeLany, J.P., Ravussin, E.: Validation and reliability of
physical activity records and accelerometers by comparison with doubly labeled water. Obes Res 12
(Supplement):195, 2004. (poster)
3) Frisard, M.I., Larson-Meyer, D.E., Heilbronn, L.K., Newcomer, B.R., Russell, R.D., Ravussin, E.: Muscle
and liver lipid content in overweight subjects: effect of race and sex and relation to insulin sensitivity. Obes
Res. 12 (Supplement):A32, 2004. (poster)
4) Larson-Meyer, D.E., Russell, R.D., Ravussin, E.: Effect of dietary fat on endurance performance and
cardiovascular risk factors in runners. Med Sci Sports Exerc. 37:276, 2005. (poster)
5) Russell, R.D., Ravussin, E., Larson-Meyer, D.E.: Effect of diet and intense running on plasma ghrelin and
PYY. Med Sci Sports Exerc. 38:S486-S487, 2006. (poster)
6) Wood, R.H., Ellis, R.G., McCarter, K.S., Fabre, J.M., Antikainen, I.E., Moore, D.S., Page, P., Russell, R.D.,
Holton, F.B., Singh, S.: Socio-cultural factors and falls risk factors among independent-living older adults.
Med Sci Sports Exerc. 39:S416, 2007. (poster)
7) Ellis, R., McCarter, K.S., Fabre, J.M., Antikainen, I.E., Moore, D.S., Page, P., Russell, R.D., Holton, F.B.,
Shivani, S., Wood, R.H.: Construct validity of a comprehensive falls risk screening instrument. Med Sci Sports
Exerc. 39:S419, 2007. (poster)
8) Welsch, M.A., Dobrosielski, D.A., Arce-Esquivel, A.A., Russell, R.D., Ravussin, E., Frisard, M.I.: Daily
physical activity and brachial artery flow mediated dilation in older adults. Med Sci Sports Exerc 39
(Supplement):S20, 2007. (poster)
9) Russell, R.D., Credeur, D.P., Arce-Esquivel, A.A., Welsch, M.A., Francis, J., Mariappan, N., Changes in pro-
and anti-oxidants and vascular reactivity before and after acute exercise. Med Sci Sports Exerc. 40
(Supplement):S287, 2008. (poster)
10) Credeur, D.P., Russell, R.D., Welsch, M.A.: Brachial artery retrograde flow increases with age: Influence on
physical function. Med Sci Sports Exerc. 40 (Supplement):S308, 2008. (poster)
11) Holton, F., Ellis, R.G., Kosma, M., Cherry, K., Antikainen, I.E., Russell, R.D., Wood, R.H.: Predictors of
ADL disability in culturally diverse older adults. Med Sci Sports Exerc. 40(Supplement):S487, 2008. (poster)

8. 12) Russell, R.D., Credeur, D.P., Dobrosielski, D.A., Parish, T.R., Welsch, M.A.: Changes in vascular and
physical function with exercise training in the aged. Med Sci Sports Exerc. 41:65-66 May 2009. (poster)
13) Russell, R.D., Credeur, D.P., Dobrosielski, D.A., Parish, T.R., Welsch, M.A., Jazwinski, S.M.: Changes in
vascular and physical function with exercise training in the oldest old. Southeast Chapter of American College
of Sports Medicine Annual Meeting, 2009. (Oral presentation)
14) Credeur. D.P., Johansson, D., Russell, R.D., Dobrosielski, D.A., Arce-Esquivel, A.A., Ravussin, E, Welsch,
M.A.: Association between vascular structure, reactivity, and physical function: mediating role of
homocysteine. Med Sci Sports Exerc. 43 (Supplement):S736, 2009. (poster)
15) Russell, R.D., Nelson, A.G.: Fasting blood-glucose changes in diabetic offspring and controls with seven
weeks of resistance training. Med Sci Sports Exerc. 42 (Supplement):S340, 2010. (poster)
16) Russell, R.D., Nelson, A.G., Kraemer, R.R.: Metabolic inflexibility: the link connecting diabetics with first
and second degree offspring of diabetes?. FASEB J 25:720.4, 2011. (poster)
17) Russell, R.D., Nelson, A.G., McMillan, R.P., Hulver, M.W., Davis, G.R., Van Dijk, J.W.: Reduced
lipotoxicity markers in diabetic offspring and controls with resistance training. Med Sci Sports Exerc. 43:559,
2011. (poster)
18) Davis, G.R., Russell, R.D., Nelson, A.G., Kokkonen, J.: Effects of acute cyclooxygenase inactivation on
glucose tolerance in diabetic offspring. Med. Sci. Sports Exerc. 43:559, 2011. (poster)
19) Wu, P.T., Russell, R.D., Thomas, A.P., Tse, C., Shadid, H.R., Thyfault, J.P., Roberts, C.K., FACSM.: Effects
of Low-Glycemic Load Diet and Resistance Training on Postprandial Glycemic Variability. Med Sci Sports
Exerc. Ahead of print. ACSM Annual meeting, Orlando, Florida. 2014. (Poster)
20) Ryan D. Russell, Shadid, H.R., Thomas, A.P., Wu, P.T., Chronley, M.K., Tse, C., Popish, A.H., and Roberts,
C.K.: Resistance Training Improves Glycemic Control Independent of Dietary Glycemic Variation. Diabetes
Supplement. Ahead of print. ADA Annual meeting, San Francisco, CA. 2014. (Poster)
INVITED LECTURES
2010
A Cursory Examination of Metabolic Dysfunction with Diabetes: Where Does it All Start? U.S. Army
Research Institute for Environmental Medicine (USARIEM), Natick, MA. August 10th
, 2010.
Diabetes Metabolism, Where Does it All Start? Maastricht University, Maastricht, NL. November 30th
, 2010.
2011
Impaired Metabolic Function in Healthy Diabetic Offspring: Deviations in Metabolic Flexibility. University of
Maryland Medical School, Baltimore, MD. May 5th
, 2011.
2013
Diabetes Metabolism: A Macro to Micro Approach. UCLA, Exercise and Metabolic Disease Laboratory. June
4th
, 2013.
Diabetes Metabolism: A Macro to Micro Approach. University of Michigan, Dept. of Kinesiology, Anne Arbor,
MI. Aug 7th
, 2013.

9. 2014
A Translational Approach to Cardiometabolic Syndrome: From Molecule to Man. Auburn University at
Montgomery, Dept. of Kinesiology, Montgomery, AL. July 15th
, 2014.
2015
A Familial Model of Microvascular Inflexibility. Menzies Institute for Medical Research, 21 Liverpool Street,
Hobart, TAS Australia. June 25, 2015.
SERVICE
MANUSCRIPT REVIEWER
Experimental Gerontology
Journal of Science and Medicine in Sport
Journal of Sports Science and Medicine
Sports Medicine
Medicine and Science in Sports and Exercise
American Journal of Physiology
GRANT REVIEWER
National Health and Medical Research Council (NHMRC) Project Grant reviewer (2016)
SERVICE TO THE UNIVERSITY/COMMUNITY
Committee member of the Medical Science Precinct Health and Wellness Committee
Menzies Community Outreach Exercise Initiative – Chair