IntraLase has expanded internationally with 182 laser systems installed outside the US as of mid-2006, comprising 40% of their total installed base. A survey of 78 IntraLase customers in 7 countries found that revenues increased 28-92% after adopting IntraLase, with price increases in 6 countries and volume increases in all 7. Adoption rates within practices varied by country from 55% in Spain to over 95% in Asia/Pacific markets. Each country profile provided details on the LASIK market, number of IntraLase placements, and impact of IntraLase on prices, volumes, revenues and adoption rates.
Intra lase's international expansion a growing global presence
1. IntraLase's International Expansion
A Growing Global Presence
8 Shareef Mahdavi • SM2 Consulting • Pleasanton, CA 7
Twenty years after laser vision correction was first per- Results
formed, the technology utilized in the procedure today has Data were collected from 78 customers in 7 markets. This
improved dramatically to make the procedure (now known as survey sample encompasses customers across three major
“LASIK”) even safer and better than before. One of the key regions (North America, Europe, and Asia Pacific) where
transitions currently underway in many markets is in how the IntraLase technology has been introduced to surgeons and
corneal flap is created, moving from a “bladed” approach with patients (see Figure 2).
traditional microkeratomes to an “all laser” approach utiliz-
ing the femtosecond laser as well as the excimer. For the Fig. 2: % Change in LASIK Revenue for IntraLase Surgeons
past 3 years, SM2 Consulting has conducted a survey of US After IntraLase vs. Prior to IntraLase
surgeons who utilize the IntraLase FS laser (IntraLase Corp., 100%
+92%
Irvine, CA), in order to assess the impact of the technology on
90%
80% +78%
key business metrics within the refractive surgery practice. In 70%
that time, the US installed base has grown from 41 units to
60%
+46% +49%
50%
289 units. CE mark for the laser was issued in March 2004, 40%
+30% +31% +28%
and the company began actively commercializing its technol-
30%
20%
ogy in Europe and select Asian Pacific markets. This year, our 10%
firm was asked by IntraLase to conduct a similar survey in Country
IntraLase Units
Canada
N=13
Germany
N=13
Spain
N=19
Switzerland
N=4
Aus/NZ
N=10
Hong Kong
N=7
Japan
N=12
markets outside the United States, an installed base of 182 Price Change +19% +23% +23% +40% +25% +33% -37%
units that comprises 40% of all customers worldwide as of Q2 Volume Change +10% +19% +6% +37% +2% +11% +182%
2006 (see Figure 1).
Changes in Business Metrics with IntraLase
Fig. 1: IntraLase Installed Base – Cumulative
USA Revenue Data were analyzed to compare changes from before
289
300
to after the incorporation of IntraLase technology into the prac-
International 243
250 tice. Customers in all markets have typically seen an increase in
200
182
LASIK revenue (calculated by multiplying the average procedure
166
150
volume by the average collected fee per eye, both before and
128
96 after). Analysis of the change between the two periods shows
100
51
that on a percentage basis, revenues are up for IntraLase cus-
50
10 tomers ranging from 28% to 92% (see Figure 2). The table
2003 2004 2005 Q2 2006
below the chart shows proportionally the percentage changes
in both price and volume in each market. IntraLase customers’
Methodology prices have increased since introducing the technology in six of
A survey tool was developed to collect data on average price seven markets, and procedure volume has increased in all seven
per eye, procedure volume, conversion rates of patients (from markets.
consultation to surgery), and adoption of IntraLase within the
practice. Countries were considered for inclusion that have suf- Price Traditionally, surgeons adopting IntraLase technology
ficient experience with the technology (ie, 12 months or more have raised their fees for LASIK. Six of the seven markets had
since commercial introduction) and represent a diverse geog- fee increases. After converting local currencies to US dollars,
raphy across major regions around the globe. Follow-up inter- the average premium fee increase ranges from $352 per eye
views were conducted with customers and distributors to bring (Canada) to $894 per eye (Switzerland). These fee increases rep-
context and perspective to the quantitative data. resent a 19% to 40% premium above earlier pricing for stan-
1
2. dard LASIK. By comparison, US surgeons showed an increase of (Germany) to 14% (Australia/New Zealand). Spain, with a pre-
$394 per eye (24% higher than non-IntraLase fees) in the most existing conversion of 98%, had little room for improvement.
recent survey in 2005. Japan, by contrast, saw fee decreases
averaging $575 (37%) in its market. Japan’s market dynamics Adoption In the Asia/Pacific markets, IntraLase is used by
are extremely different than those of other major markets and its customers nearly exclusively (95% to 99%). IntraLase is
are explained more fully in a later section. A summary of LASIK used for the vast majority of cases by IntraLase customers in
prices in each market is shown in Figure 3. Switzerland (86%), Canada (84%), and Germany (72%). The
anomaly here is Spain at 55% of cases, which will be discussed
Fig. 3: LASIK Pricing per Eye further below. See Figure 5.
Before and After IntraLase (US Dollars)
Premium Fig. 5: Adoption of IntraLase within the Practice
Fees
Weighted Average: % of LASIK performed with IntraLase
$1,842 Can $2,194 +$352
99%
100% 96% 95%
$2,583 Germany $3,177 +$594
84% 86%
80%
72%
$1,157 Hong Kong $1,543 +$386
60%
55%
$1,976 Aus/ N Z $2,470 +$494
40%
$1,503 Spain $1,851 +$349 20%
$2,234 Switzerland $3,128 +$894
Canada Germany Spain Switzerland Aus/NZ Hong Kong Japan
$1,050 Japan $1,625 -$575
Market-by-Market Summary
$1,000 $1,500 $2,000 $2,500 $3,000 $3,500
Procedure Volume The change in the average number of Canada – “Premium
total LASIK procedures performed each month ranges from a Market Recovery” CANADA
modest 2– 6% (two markets) to a moderate 11 – 37% (four With the excimer Population: 32 Million
markets) to an extreme 182% increase in Japan. Other tech- laser available commer- Number of Laser Centers: 69
nologies, such as customized wavefront, have been in place in cially in 1990, Canada Number of IntraLase Placements: 13
these markets and does not account for the differences seen in is the world’s most 2006 # of LASIK eyes (est): 90,000
this survey. In the case of Japan, it appears that procedure pric- experienced market with 2006 # of IntraLase eyes (est): 20,000
ing has had a highly significant impact on procedure volume. laser vision correction.
Volume changes are summarized in Figure 4. Peaking with over 120 centers in the late 1990s, the impact of
negative media attention and discount pricing led to a “shake-
Fig. 4: Average Total LASIK Procedures (Eyes) per Month out” that has settled currently at 69 excimer laser centers.
Before and After IntraLase IntraLase technology, which was introduced commercially in
MARKET BEFORE AFTER INCREASE % INCREASE
2005, has experienced the most rapid adoption of any technol-
ogy for laser vision correction, with installations in 13 centers
Canada 152 168 16 11%
Germany 85 101 16 19% during the past 18 months. Surgeons report that the technology
Spain 110 117 7 6% appeals to those who were ready for LASIK as well as expand-
Switzerland 73 100 27 37%
Aus/NZ 130 133 3 2%
ing interest in the population by touting an “increased margin
Hong Kong 61 68 7 11% of safety” message analogous to the advent of airbags and ABS
Japan 135 381 246 182% braking systems for automobiles.
Such comparisons are easily communicated and understood,
Conversion Rates to Surgery Data on the movement of allowing large and small volume centers to increase prices, with
patients from the consultation to surgery were available for five 7 of 13 centers prices now $CDN 400 – 700 higher per eye.
of the seven markets (not reliably tracked in Japan or Hong Additionally, surgeons report that multiple IntraLase users in
Kong). Improved conversion rates were seen ranging from 3% the same market has been beneficial to conversion and volume.
2
3. In 2006, it is likely that 20,000 of the 90,000 LASIK proce- However, the increases in price, volume and revenue are
dures will be performed with IntraLase, a share that is rapidly consistent with other markets, and IntraLase surgeons are not
moving towards a national tipping point where the top 30 reporting loss of patients to other providers. With greater expe-
centers will eventually use IntraLase to initiate the majority of rience, it is reasonable to expect that adoption by Spanish sur-
procedures performed in the market. geons within their practices will more closely mirror that seen in
other markets. It simply will take longer to achieve. Adoption
Germany – will also be impacted by increased availability of the technol-
“Market Validation” GERMANY ogy; more installed base leads to more awareness among both
As with Canada, Population: 82 Million surgeons and patients.
Germany is often the Number of Laser Centers: 200
first market entry point Number of IntraLase Placements: 13 Switzerland –
for new ophthalmic 2006 # of LASIK eyes (est): 90,000 “No Compromise” SWITZERLAND
technology. IntraLase’s 2006 # of IntraLase eyes (est): 11,500 Swiss consumers, Population: 7 Million
success has resulted in unlike their German Number of Laser Centers: 20
large part because introduction came after FDA approval and counterparts, have not Number of IntraLase Placements: 4
validation by surgeons in the United States, a unique feature of been enticed for dis- 2006 # of LASIK eyes (est): 6,000
the product which is valued by the primarily higher volume sur- count surgery offered 2006 # of IntraLase eyes (est): 4,200
geons who have adopted IntraLase. Demand for LASIK is down abroad. Swiss patients
from a peak of 120,000 eyes per year, and IntraLase surgeons want surgery from Swiss surgeons. Although small in size at
are striving to rebuild with a new message for consumers. With 6000 procedures per year, the market is now dominated by four
the new IEK application for corneal transplant surgery, German centers that each use IntraLase technology, accounting for 7
universities are adding the IntraLase platform, serving as further of every 10 procedures done in the country. Price increases for
validation of the technology for the next wave of private prac- IntraLase are the highest seen globally; the success in achieving
tice surgeons. IntraLase’s success is noteworthy in the face of the majority position was helped in part by live surgery per-
three domestic German manufacturers and one Swiss entity that formed in primetime on Swiss television.
have or plan to launch competing femtosecond laser platforms.
Australia &
Spain – “Culturally New Zealand – AUSTRALIA/NZ
Influenced” SPAIN “Turning the Tide” Population: 24 Million
Consumer demand Population: 40 Million The first IntraLase Number of Laser Centers: 24
and acceptance for Number of Laser Centers: 220 customer placement Number of IntraLase Placements: 10
LASIK is among the Number of IntraLase Placements: 19 (late 2004) in Australia 2006 # of LASIK eyes (est): 28,000
highest seen in Europe 2006 # of LASIK eyes (est): 180,000 was already a “pre- 2006 # of IntraLase eyes (est): 15,000
with 180,000 LASIK 2006 # of IntraLase eyes (est): 15,000 mium” priced center
procedures in 220 and increased their fees to $3,250 per eye, more than double
centers predicted for 2006. Surgeon influence on medical deci- the average price in the market at that time. Under heavy bar-
sions transcends the impact of any advertising or promotion for rage of negative advertising from the centers doing traditional
LASIK. Citizens with private insurance have benefitted from bladed LASIK, this first customer saw a slight increase in vol-
pre-negotiated rates by major carriers, which only now are ume for calendar 2005 over the prior year. Since that time, there
beginning to include an optional fee for IntraLase. These car- is now system wide acceptance as 10 of the 25 centers now use
riers are a prime source of patient referrals, and surgeons are IntraLase nearly exclusively (95% or more of cases) and account
hesitant to make any changes to a system that already turns for the majority of LASIK procedures (15,000/28,000 or 54%).
high conversion rates into a large volume of LASIK procedures Surgeons report that patients are more engaged, optometrists
nationally. This built-in resistance has delayed IntraLase technol- now have a reason to offer patients as to why fees are what
ogy from becoming part of the standard surgeon-patient conver- they are, and staff members find it easier to convert interest into
sation for fear of losing patients, which helps make sense of the procedures. The Australian and New Zealand markets should
lower adoption rate. experience continued steady growth over the next few years.
3