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Ch9bppt hormones honors
1.
PowerPoint® Lecture Slide
Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College The Endocrine System 9 PART A Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
2.
The Chemistry of
Hormones Hormones are classified chemically as Amino acid–based, which includes Proteins Peptides Amines Steroids—made from cholesterol Prostaglandins—made from highly active lipids Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
3.
Mechanisms of Hormone
Action Hormones affect only certain tissues or organs (target cells or target organs) Target cells must have specific protein receptors Hormone-binding alters cellular activity Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
4.
The Chemistry of
Hormones Two mechanisms in which hormones act Direct gene activation Second-messenger system Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
5.
Direct Gene Activation (Steroid
Hormone Action) Diffuse through the plasma membrane of target cells Enter the nucleus Bind to a specific protein within the nucleus Bind to specific sites on the cell’s DNA Activate genes that result in synthesis of new proteins Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
6.
Steroid hormone Nucleus Cytoplasm Receptor protein Hormone-receptor complex DNA mRNA New protein Plasma membrane of target cell PLAY Steroid
Hormone Figure 9.1a Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
7.
Second-Messenger System (Nonsteroid Hormone
Action) Hormone binds to a membrane receptor Hormone does not enter the cell Sets off a series of reactions that activates an enzyme Catalyzes a reaction that produces a secondmessenger molecule Oversees additional intracellular changes to promote a specific response Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
8.
Nonsteroid hormone (first messenger) Cytoplasm Enzyme ATP cAMP Receptor protein Plasma membrane of target
cell Second messenger Effect on cellular function, such as glycogen breakdown PLAY Nonsteroid Hormone Figure 9.1b Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
9.
Control of Hormone
Release Hormone levels in the blood are mostly maintained by negative feedback A stimulus or low hormone levels in the blood triggers the release of more hormone Hormone release stops once an appropriate level in the blood is reached Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
10.
Control of Hormone
Release Hormone levels in the blood are mostly maintained by negative feedback A stimulus or low hormone levels in the blood triggers the release of more hormone Hormone release stops once an appropriate level in the blood is reached Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
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