2. • InSightec ExAblate™ system.
• “Most Advanced MRgFUS system in India”
• One of the few centers in the world to offer both MRgFUS and
Uterine Fibroid Embolization
• Since 2004, over 9000 women have been treated with
ExAblate for their uterine fibroids.
3. How does MRgFUS work ?
• ExAblate uses a combination of high-intensity ultrasound
waves and MRI to non-invasively image the fibroid and
surrounding organs in 3D, treat the fibroid, obtain real-time
feedback about the treated area, and observe what has been
treated.
• The high intensity focused ultrasound energy heats the fibroid
only at the target area, producing safe and controlled
coagulative necrosis without damaging the surrounding
tissue.
• The treatment procedure lasts about 3 hours, and patients
return to regular activities within a few days.
4. Beam path visualization
2 for controlled treatment
4 3
1
Multi-planar imaging
for precise tumor
targeting
CLOSED
LOOP
THERAPY
5
MR thermometry
temperature feedback Thermal dose accumulation
Post treatment
contrast imaging for
precise treatment
validation
Real Time MRI Guidance and Monitoring
5. Who can be treated by MRgFUS ?
• Fibroids greater than 2cm and smaller than 20cm are
particularly amenable to treatment with the most noticeable
symptomatic relief from bleeding and pressure symptoms.
• A screening MRI is done that gives us information about the
size, location, number, T2 Hyperintensity and Post contrast
enhancement characteristics.
• These help us choose the best modality to treat your patient’s
fibroid.
6. Contraindications for MRgFus :
• MR incompatible implantable medical devices such as pacemakers
and cochlear implants.
• Severe claustrophobia.
• Known intolerance to MR contrast agents.
• Vertical abdominal or high horizontal scars through the mid-line
which would prevent access to the fibroid (low horizontal scars such
as normal Caesarean section scars or scars to either side of the mid-line
such as appendectomy scars are not a contra-indication).
• Such patients can be treated by Uterine Fibroid Embolization.
7. MRgFUS & Pregnancy ?
Total number of pregnancies
Mean age
Average months to conception
Total deliveries
- Of them vaginal
Elective pregnancy termination
Spontaneous abortions
Ongoing pregnancies
Unknown
Average baby weight at term
delivery
117
36
9
64 (55%)
59%
10 (9%)
22 (19%)
9 (8%)
12 (10%)
3.27 kg
8. Pre
Procedur
e T2
Coronal
Post
Procedure
80 % NPV
Patients treated at Nanavati Supersepciality
Hospital
Patient 1 : 34 yr old female
Symptoms: Heavy menstrual bleeding, pelvic
pain and urinary frequency
T2 Hypointense heterogeneous fibroid.
Treatment time: 3 hours, 30 mins
Results: 90% NPV with no adverse events
Non Perfused Volume denotes the volume of
fibroid that is no longer viable.
9. Patients treated at Nanavati Supersepciality
Hospital
Patient 2 : 33 yr old female
Symptoms: Heavy menstrual bleeding, pelvic
pain and constipation
T2 Hypointense heterogeneous fibroid.
Treatment time: 3 hours, 40 mins
Results: 90% NPV with no adverse events
Non Perfused Volume denotes the volume of
fibroid that is no longer viable.
Pre
Procedure
T2 Sagittal
Post
Procedure
80 % NPV
10. More Information ?
• www.veincenter.in
• SMS : Vein Fibroid to 56677 ( India Only )