SlideShare una empresa de Scribd logo

NAFLD, NASH

•Descargar como PPT, PDF•
•
Shatdal Chaudhary
Shatdal Chaudhary

This presentation is meant for MBBS students

Entretenimiento y humorDeportes
1 de 42
DR. Shatdal Chaudhary MD ,[object Object]
N on- A lcoholic F atty L iver D isease (NAFLD) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
N on- A lcoholic F atty L iver D isease (NAFLD) Fatty liver (Steatosis) Steatohepatitis - inflammation - fibrosis Cirrhosis Normal liver
The Brief History of NAFLD Fatty Liver Disease: NASH and Related Disorders Blackwell Publishing, 2005 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Prevalence of fatty liver ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NAFLD 1. Most common of all liver disorders. 2. Frequent cause of chronic liver disease. 3. Present in 3% of children and >50% of obese children. Fatty Liver Disease: NASH and Related Disorders Blackwell Publishing, 2005
Prevalence of NAFLD In General Population In Asian Pacific Region ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Prevalence of NAFLD In High Risk Population In Asian Pacific Region ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Aetiological Classification ,[object Object],[object Object]
Types of NAFLD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Morbid Obesity ,[object Object],[object Object],[object Object],[object Object],Abrams GA, et al.  Hepatology 2004;40:475-483; Frantzides CT, et al.  J Gastrointest Surg 2004;8:849-855; Dallal RM, et al. Obes Surg 2004;14:47-53; Beymer C, et al.  Arch Surg 2003;138:1240-1244.
Type 2 Diabetes Mellitus ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Gupte, et al.  J Gastro Hepatol 2004;19:854-858.
Dyslipidemia ,[object Object],[object Object],[object Object],[object Object],Assy N, et al. Dig Dis Sci 2000;45:1929-1934.
Pathophysiology Salgado W, et al. Acta Cir. Bras. 2006; 21.  
Two-hit Hypothesis Fatty Liver 1 st Hit Damaged Liver 2 nd Hit Oxidative Stress Toxins Inflammatory Molecules Susceptibility Donnelly et al. J. Clin. Invest. 113: 1343, 2005 Day and James. Gastroenterol. 114: 842, 1998 Diet FFA Burned VLDL-TG
Liver Damage 2 nd Hit Liver Damage Sat FA 2 nd Hit Apoptosis Hepatocyte Mass Fatty Liver
Pathophysiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathophysiology: others ,[object Object],[object Object],[object Object],[object Object]
Pathophysiology: others ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Presentation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Natural history and clinical outcomes of NASH ,[object Object],[object Object],[object Object],[object Object]
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Lab Studies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis ,[object Object]
Diagnosis (cont.) ,[object Object],[object Object]
Diagnosis (cont.) ,[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Histology ,[object Object],[object Object]
Histology ,[object Object],[object Object],[object Object]
Histology ,[object Object],[object Object]
COMPLICATION ,[object Object],[object Object],[object Object],[object Object]
NASH Criteria (AGA guidelines) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Prognosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Matteoni C, et al. Gastroenterology 1999;116:1413-1419.
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]
McCullough AJ. N Engl J Med 2006; 355: 2361-3.
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment (cont.) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Betaine ,[object Object],[object Object],[object Object]
Pentoxifylline ,[object Object],[object Object],[object Object]
Probucol ,[object Object],[object Object]

Recomendados

Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Alcoholic Fatty Liver Disease (NAFLD)Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Alcoholic Fatty Liver Disease (NAFLD)Sariu Ali
 
Non alcoholic fatty liver disease(NAFLD)
Non alcoholic fatty liver disease(NAFLD)Non alcoholic fatty liver disease(NAFLD)
Non alcoholic fatty liver disease(NAFLD)Bhavin Mandowara
 
Non alcoholic steatohepatitis copy
Non alcoholic steatohepatitis copyNon alcoholic steatohepatitis copy
Non alcoholic steatohepatitis copyKeshri Yadav
 
Nonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseAshish Kumar
 
NON ALCOHOLIC FATTY LIVER DISEASE
NON ALCOHOLIC FATTY LIVER DISEASENON ALCOHOLIC FATTY LIVER DISEASE
NON ALCOHOLIC FATTY LIVER DISEASEDr. Haritha Sridhar
 
Nafld
NafldNafld
NafldRajesh Mandal
 
Metabolic syndrome
Metabolic syndromeMetabolic syndrome
Metabolic syndromeAlisha Talwar
 
Dyslipidaemia presentation
Dyslipidaemia presentationDyslipidaemia presentation
Dyslipidaemia presentationrajeetam123
 

Recomendados

Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Alcoholic Fatty Liver Disease (NAFLD)Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Alcoholic Fatty Liver Disease (NAFLD)Sariu Ali
 
Non alcoholic fatty liver disease(NAFLD)
Non alcoholic fatty liver disease(NAFLD)Non alcoholic fatty liver disease(NAFLD)
Non alcoholic fatty liver disease(NAFLD)Bhavin Mandowara
 
Non alcoholic steatohepatitis copy
Non alcoholic steatohepatitis copyNon alcoholic steatohepatitis copy
Non alcoholic steatohepatitis copyKeshri Yadav
 
Nonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseAshish Kumar
 
NON ALCOHOLIC FATTY LIVER DISEASE
NON ALCOHOLIC FATTY LIVER DISEASENON ALCOHOLIC FATTY LIVER DISEASE
NON ALCOHOLIC FATTY LIVER DISEASEDr. Haritha Sridhar
 
Nafld
NafldNafld
NafldRajesh Mandal
 
Metabolic syndrome
Metabolic syndromeMetabolic syndrome
Metabolic syndromeAlisha Talwar
 
Dyslipidaemia presentation
Dyslipidaemia presentationDyslipidaemia presentation
Dyslipidaemia presentationrajeetam123
 
Nafld
NafldNafld
Nafldakifab93
 
Non alcoholic fatty liver disease
Non alcoholic fatty liver disease Non alcoholic fatty liver disease
Non alcoholic fatty liver disease Akuffo Quarde
 
Autoimmune hepatitis rajesh
Autoimmune hepatitis rajeshAutoimmune hepatitis rajesh
Autoimmune hepatitis rajeshMohit Aggarwal
 
Nafld suresh ppt
Nafld suresh pptNafld suresh ppt
Nafld suresh pptSuresh Gorka
 
9. metabolic syndrome
9. metabolic syndrome9. metabolic syndrome
9. metabolic syndromeMadhumita Sen
 
ALCOHOLIC LIVER DISEASE
ALCOHOLIC LIVER DISEASEALCOHOLIC LIVER DISEASE
ALCOHOLIC LIVER DISEASERakesh Kumar
 
Chronic pancreatitis
Chronic pancreatitisChronic pancreatitis
Chronic pancreatitisikramdr01
 
Metabolic syndrome & its complications
Metabolic syndrome & its complicationsMetabolic syndrome & its complications
Metabolic syndrome & its complicationsPradeep Singh Narwat
 
Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Kailash Raj
 
Fatty liver
Fatty liverFatty liver
Fatty liverShahin Hameed
 
Non Alcoholic Fatty Liver Disease
Non Alcoholic Fatty Liver DiseaseNon Alcoholic Fatty Liver Disease
Non Alcoholic Fatty Liver DiseaseShahadad Hossain
 
Autoimmune Hepatitis
Autoimmune HepatitisAutoimmune Hepatitis
Autoimmune HepatitisPratap Tiwari
 
Chronic pancreatitis
Chronic pancreatitisChronic pancreatitis
Chronic pancreatitisprabhanjan chakravarthy
 
Alcoholic Hepatitis
Alcoholic HepatitisAlcoholic Hepatitis
Alcoholic HepatitisElmuhtady Said FRCP FEBGH
 
Management of dyslipidemia
Management of dyslipidemiaManagement of dyslipidemia
Management of dyslipidemiaAmir Mahmoud
 
Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Usama Ragab
 
NAFLD
NAFLDNAFLD
NAFLDVadivel Kumaran Sivasankaran
 
Primary Biliary Cholangitis
Primary Biliary CholangitisPrimary Biliary Cholangitis
Primary Biliary CholangitisPratap Tiwari
 
Hepato&spleenomegaly
Hepato&spleenomegalyHepato&spleenomegaly
Hepato&spleenomegalySubash Arun
 
Approach to cholestatic jaundice
Approach to cholestatic jaundiceApproach to cholestatic jaundice
Approach to cholestatic jaundiceRam Raut
 
global nash market
global nash marketglobal nash market
global nash marketPreeti Singh
 
Nonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseAshok Moses
 

Más contenido relacionado

La actualidad más candente

Non alcoholic fatty liver disease
Non alcoholic fatty liver disease Non alcoholic fatty liver disease
Non alcoholic fatty liver disease Akuffo Quarde
 
Autoimmune hepatitis rajesh
Autoimmune hepatitis rajeshAutoimmune hepatitis rajesh
Autoimmune hepatitis rajeshMohit Aggarwal
 
9. metabolic syndrome
9. metabolic syndrome9. metabolic syndrome
9. metabolic syndromeMadhumita Sen
 
ALCOHOLIC LIVER DISEASE
ALCOHOLIC LIVER DISEASEALCOHOLIC LIVER DISEASE
ALCOHOLIC LIVER DISEASERakesh Kumar
 
Chronic pancreatitis
Chronic pancreatitisChronic pancreatitis
Chronic pancreatitisikramdr01
 
Metabolic syndrome & its complications
Metabolic syndrome & its complicationsMetabolic syndrome & its complications
Metabolic syndrome & its complicationsPradeep Singh Narwat
 
Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Kailash Raj
 
Non Alcoholic Fatty Liver Disease
Non Alcoholic Fatty Liver DiseaseNon Alcoholic Fatty Liver Disease
Non Alcoholic Fatty Liver DiseaseShahadad Hossain
 
Autoimmune Hepatitis
Autoimmune HepatitisAutoimmune Hepatitis
Autoimmune HepatitisPratap Tiwari
 
Management of dyslipidemia
Management of dyslipidemiaManagement of dyslipidemia
Management of dyslipidemiaAmir Mahmoud
 
Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Usama Ragab
 
Primary Biliary Cholangitis
Primary Biliary CholangitisPrimary Biliary Cholangitis
Primary Biliary CholangitisPratap Tiwari
 
Hepato&spleenomegaly
Hepato&spleenomegalyHepato&spleenomegaly
Hepato&spleenomegalySubash Arun
 
Approach to cholestatic jaundice
Approach to cholestatic jaundiceApproach to cholestatic jaundice
Approach to cholestatic jaundiceRam Raut
 

La actualidad más candente (20)

Nafld
NafldNafld
Nafld
 
Non alcoholic fatty liver disease
Non alcoholic fatty liver disease Non alcoholic fatty liver disease
Non alcoholic fatty liver disease
 
Autoimmune hepatitis rajesh
Autoimmune hepatitis rajeshAutoimmune hepatitis rajesh
Autoimmune hepatitis rajesh
 
Nafld suresh ppt
Nafld suresh pptNafld suresh ppt
Nafld suresh ppt
 
9. metabolic syndrome
9. metabolic syndrome9. metabolic syndrome
9. metabolic syndrome
 
ALCOHOLIC LIVER DISEASE
ALCOHOLIC LIVER DISEASEALCOHOLIC LIVER DISEASE
ALCOHOLIC LIVER DISEASE
 
Chronic pancreatitis
Chronic pancreatitisChronic pancreatitis
Chronic pancreatitis
 
Metabolic syndrome & its complications
Metabolic syndrome & its complicationsMetabolic syndrome & its complications
Metabolic syndrome & its complications
 
Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)
 
Fatty liver
Fatty liverFatty liver
Fatty liver
 
Non Alcoholic Fatty Liver Disease
Non Alcoholic Fatty Liver DiseaseNon Alcoholic Fatty Liver Disease
Non Alcoholic Fatty Liver Disease
 
Autoimmune Hepatitis
Autoimmune HepatitisAutoimmune Hepatitis
Autoimmune Hepatitis
 
Chronic pancreatitis
Chronic pancreatitisChronic pancreatitis
Chronic pancreatitis
 
Alcoholic Hepatitis
Alcoholic HepatitisAlcoholic Hepatitis
Alcoholic Hepatitis
 
Management of dyslipidemia
Management of dyslipidemiaManagement of dyslipidemia
Management of dyslipidemia
 
Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis (PSC)
 
NAFLD
NAFLDNAFLD
NAFLD
 
Primary Biliary Cholangitis
Primary Biliary CholangitisPrimary Biliary Cholangitis
Primary Biliary Cholangitis
 
Hepato&spleenomegaly
Hepato&spleenomegalyHepato&spleenomegaly
Hepato&spleenomegaly
 
Approach to cholestatic jaundice
Approach to cholestatic jaundiceApproach to cholestatic jaundice
Approach to cholestatic jaundice
 

Destacado

global nash market
global nash marketglobal nash market
global nash marketPreeti Singh
 
Nonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseAshok Moses
 
Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...
Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...
Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...DelveInsight Business Research
 
Non Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar Slides
Non Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar SlidesNon Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar Slides
Non Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar SlidesCovance
 
How profitable is it to invest in NASH market?
How profitable is it to invest in NASH market?How profitable is it to invest in NASH market?
How profitable is it to invest in NASH market?Allied Market Research
 
Nonalcoholic steatohepatitis market
Nonalcoholic steatohepatitis marketNonalcoholic steatohepatitis market
Nonalcoholic steatohepatitis marketDavid Moore
 

Destacado (6)

global nash market
global nash marketglobal nash market
global nash market
 
Nonalcoholic fatty liver disease
Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease
Nonalcoholic fatty liver disease
 
Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...
Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...
Nonalcoholic steatohepatitis (NASH) market insights, epidemiology and market...
 
Non Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar Slides
Non Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar SlidesNon Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar Slides
Non Invasive Biomarkers in NASH (non-alcoholic steatohepatitis) Webinar Slides
 
How profitable is it to invest in NASH market?
How profitable is it to invest in NASH market?How profitable is it to invest in NASH market?
How profitable is it to invest in NASH market?
 
Nonalcoholic steatohepatitis market
Nonalcoholic steatohepatitis marketNonalcoholic steatohepatitis market
Nonalcoholic steatohepatitis market
 

Similar a NAFLD, NASH

MAFLD, a new name of an old disease
MAFLD, a new name of an old diseaseMAFLD, a new name of an old disease
MAFLD, a new name of an old diseaseEl-Sayed Tharwa
 
GIT J Club: NAFLD.
GIT J Club: NAFLD.GIT J Club: NAFLD.
GIT J Club: NAFLD.Shaikhani.
 
NON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptx
NON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptxNON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptx
NON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptxKyawMyoHtet10
 
Common liver Disease in Primary Care Setting
Common liver Disease in Primary Care SettingCommon liver Disease in Primary Care Setting
Common liver Disease in Primary Care SettingChernHaoChong
 
Hígado graso no alcohólico en niños y adolescentes obesos
Hígado graso no alcohólico en niños y adolescentes obesosHígado graso no alcohólico en niños y adolescentes obesos
Hígado graso no alcohólico en niños y adolescentes obesosCuerpomedicoinsn
 
metabolic dysfunction associated steatotic liver disease -1.pptx
metabolic dysfunction associated steatotic liver disease -1.pptxmetabolic dysfunction associated steatotic liver disease -1.pptx
metabolic dysfunction associated steatotic liver disease -1.pptxCHALICHIMALASIVAIAH
 
Fatty liver disease with Diabetes Mellitus [BANGLADESH]
Fatty liver disease with Diabetes Mellitus [BANGLADESH]Fatty liver disease with Diabetes Mellitus [BANGLADESH]
Fatty liver disease with Diabetes Mellitus [BANGLADESH]drsamianik
 
metabolic dysfunction associated steatotic liver disease.pptx
metabolic dysfunction associated steatotic liver disease.pptxmetabolic dysfunction associated steatotic liver disease.pptx
metabolic dysfunction associated steatotic liver disease.pptxCHALICHIMALASIVAIAH
 
ACUTE PANCREATITIS.pdf
ACUTE PANCREATITIS.pdfACUTE PANCREATITIS.pdf
ACUTE PANCREATITIS.pdfShapi. MD
 
Abnormal LFTs rate of deco and NAFLD.pptx
Abnormal LFTs rate of deco and NAFLD.pptxAbnormal LFTs rate of deco and NAFLD.pptx
Abnormal LFTs rate of deco and NAFLD.pptxzeus70441
 
NASH risk factors and management.pptx
NASH risk factors and management.pptxNASH risk factors and management.pptx
NASH risk factors and management.pptxAhmedMandour37
 

Similar a NAFLD, NASH (20)

MAFLD, a new name of an old disease
MAFLD, a new name of an old diseaseMAFLD, a new name of an old disease
MAFLD, a new name of an old disease
 
GIT J Club: NAFLD.
GIT J Club: NAFLD.GIT J Club: NAFLD.
GIT J Club: NAFLD.
 
NAFLD.pptx
NAFLD.pptxNAFLD.pptx
NAFLD.pptx
 
NAFLD-Metabolic Syndrome- THE LINK
NAFLD-Metabolic Syndrome- THE LINKNAFLD-Metabolic Syndrome- THE LINK
NAFLD-Metabolic Syndrome- THE LINK
 
NON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptx
NON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptxNON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptx
NON ALCOHOLIC FATTY LIVER DISEASES modify (edited by Kyin).pptx
 
Common liver Disease in Primary Care Setting
Common liver Disease in Primary Care SettingCommon liver Disease in Primary Care Setting
Common liver Disease in Primary Care Setting
 
Hígado graso no alcohólico en niños y adolescentes obesos
Hígado graso no alcohólico en niños y adolescentes obesosHígado graso no alcohólico en niños y adolescentes obesos
Hígado graso no alcohólico en niños y adolescentes obesos
 
NAFLD
NAFLDNAFLD
NAFLD
 
metabolic dysfunction associated steatotic liver disease -1.pptx
metabolic dysfunction associated steatotic liver disease -1.pptxmetabolic dysfunction associated steatotic liver disease -1.pptx
metabolic dysfunction associated steatotic liver disease -1.pptx
 
A Case of NASH with HYPOTHYROIDISM
A Case of NASH with HYPOTHYROIDISMA Case of NASH with HYPOTHYROIDISM
A Case of NASH with HYPOTHYROIDISM
 
Aflp
AflpAflp
Aflp
 
Update on NAFLD NASH.pptx
Update on NAFLD NASH.pptxUpdate on NAFLD NASH.pptx
Update on NAFLD NASH.pptx
 
Fatty liver
Fatty liver Fatty liver
Fatty liver
 
Fatty liver disease with Diabetes Mellitus [BANGLADESH]
Fatty liver disease with Diabetes Mellitus [BANGLADESH]Fatty liver disease with Diabetes Mellitus [BANGLADESH]
Fatty liver disease with Diabetes Mellitus [BANGLADESH]
 
metabolic dysfunction associated steatotic liver disease.pptx
metabolic dysfunction associated steatotic liver disease.pptxmetabolic dysfunction associated steatotic liver disease.pptx
metabolic dysfunction associated steatotic liver disease.pptx
 
ACUTE PANCREATITIS.pdf
ACUTE PANCREATITIS.pdfACUTE PANCREATITIS.pdf
ACUTE PANCREATITIS.pdf
 
NAFLD
NAFLDNAFLD
NAFLD
 
Abnormal LFTs rate of deco and NAFLD.pptx
Abnormal LFTs rate of deco and NAFLD.pptxAbnormal LFTs rate of deco and NAFLD.pptx
Abnormal LFTs rate of deco and NAFLD.pptx
 
NASH risk factors and management.pptx
NASH risk factors and management.pptxNASH risk factors and management.pptx
NASH risk factors and management.pptx
 
NAFLD.pptx
NAFLD.pptxNAFLD.pptx
NAFLD.pptx
 

Más de Shatdal Chaudhary

Chronic Meningitis Dr. Shatdal Chaudhary
Chronic Meningitis Dr. Shatdal ChaudharyChronic Meningitis Dr. Shatdal Chaudhary
Chronic Meningitis Dr. Shatdal ChaudharyShatdal Chaudhary
 
Acute Viral encephalitis Dr. Shatdal Chaudhary
Acute Viral encephalitis Dr. Shatdal ChaudharyAcute Viral encephalitis Dr. Shatdal Chaudhary
Acute Viral encephalitis Dr. Shatdal ChaudharyShatdal Chaudhary
 
Peptic Ulcer Disease Dr Shatdal
Peptic Ulcer Disease Dr ShatdalPeptic Ulcer Disease Dr Shatdal
Peptic Ulcer Disease Dr ShatdalShatdal Chaudhary
 

Más de Shatdal Chaudhary (6)

Lumbini
LumbiniLumbini
Lumbini
 
Chronic Meningitis Dr. Shatdal Chaudhary
Chronic Meningitis Dr. Shatdal ChaudharyChronic Meningitis Dr. Shatdal Chaudhary
Chronic Meningitis Dr. Shatdal Chaudhary
 
Brain abscess dr shatdal
Brain abscess dr shatdalBrain abscess dr shatdal
Brain abscess dr shatdal
 
Acute Viral encephalitis Dr. Shatdal Chaudhary
Acute Viral encephalitis Dr. Shatdal ChaudharyAcute Viral encephalitis Dr. Shatdal Chaudhary
Acute Viral encephalitis Dr. Shatdal Chaudhary
 
Hepatocellular Carcinoma
Hepatocellular CarcinomaHepatocellular Carcinoma
Hepatocellular Carcinoma
 
Peptic Ulcer Disease Dr Shatdal
Peptic Ulcer Disease Dr ShatdalPeptic Ulcer Disease Dr Shatdal
Peptic Ulcer Disease Dr Shatdal
 

Último

Call Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls Goa
Call Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls GoaCall Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls Goa
Call Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls Goasexy call girls service in goa
 
↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...
↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...
↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...noor ahmed
 
Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...
Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...
Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...Apsara Of India
 
Kanpur call girls 📞 8617697112 At Low Cost Cash Payment Booking
Kanpur call girls 📞 8617697112 At Low Cost Cash Payment BookingKanpur call girls 📞 8617697112 At Low Cost Cash Payment Booking
Kanpur call girls 📞 8617697112 At Low Cost Cash Payment BookingNitya salvi
 
Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...
Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...
Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...aamir
 
2k Shot Call girls Laxmi Nagar Delhi 9205541914
2k Shot Call girls Laxmi Nagar Delhi 92055419142k Shot Call girls Laxmi Nagar Delhi 9205541914
2k Shot Call girls Laxmi Nagar Delhi 9205541914Delhi Call girls
 
Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...
Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...
Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...Riya Pathan
 
Russian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl Goa
Russian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl GoaRussian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl Goa
Russian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl Goasexy call girls service in goa
 
Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...
Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...
Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...rahim quresi
 
Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...
Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...
Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...aamir
 
Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...
Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...
Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...ritikasharma
 
Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...
Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...
Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...ritikasharma
 
Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser...
Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser...Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser...
Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser... Shivani Pandey
 
Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...
Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...
Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...Call Girls in Nagpur High Profile
 
Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24...
Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24...Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24...
Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24... Shivani Pandey
 
Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...
Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...
Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...ritikasharma
 
Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...
Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...
Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...noor ahmed
 
VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...
VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...
VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...SUHANI PANDEY
 
Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...
Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...
Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...ritikasharma
 

Último (20)

Call Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls Goa
Call Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls GoaCall Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls Goa
Call Girls In Goa 9316020077 Goa Call Girl By Indian Call Girls Goa
 
↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...
↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...
↑Top Model (Kolkata) Call Girls Sonagachi ⟟ 8250192130 ⟟ High Class Call Girl...
 
Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...
Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...
Karnal Call Girls 8860008073 Dyal Singh Colony Call Girls Service in Karnal E...
 
Kanpur call girls 📞 8617697112 At Low Cost Cash Payment Booking
Kanpur call girls 📞 8617697112 At Low Cost Cash Payment BookingKanpur call girls 📞 8617697112 At Low Cost Cash Payment Booking
Kanpur call girls 📞 8617697112 At Low Cost Cash Payment Booking
 
Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...
Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...
Nayabad Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Sex At ...
 
2k Shot Call girls Laxmi Nagar Delhi 9205541914
2k Shot Call girls Laxmi Nagar Delhi 92055419142k Shot Call girls Laxmi Nagar Delhi 9205541914
2k Shot Call girls Laxmi Nagar Delhi 9205541914
 
Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...
Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...
Independent Garulia Escorts ✔ 9332606886✔ Full Night With Room Online Booking...
 
Russian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl Goa
Russian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl GoaRussian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl Goa
Russian Escorts Agency In Goa 💚 9316020077 💚 Russian Call Girl Goa
 
Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...
Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...
Science City Kolkata ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sex...
 
Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...
Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...
Dakshineswar Call Girls ✔ 8005736733 ✔ Hot Model With Sexy Bhabi Ready For Se...
 
Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...
Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...
Top Rated Kolkata Call Girls Khardah ⟟ 6297143586 ⟟ Call Me For Genuine Sex S...
 
Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...
Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...
Behala ( Call Girls ) Kolkata ✔ 6297143586 ✔ Hot Model With Sexy Bhabi Ready ...
 
Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser...
Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser...Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser...
Model Call Girls In Pazhavanthangal WhatsApp Booking 7427069034 call girl ser...
 
Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...
Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...
Top Rated Pune Call Girls Pimpri Chinchwad ⟟ 6297143586 ⟟ Call Me For Genuin...
 
Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24...
Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24...Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24...
Model Call Girls In Ariyalur WhatsApp Booking 7427069034 call girl service 24...
 
Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...
Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...
Hotel And Home Service Available Kolkata Call Girls Sonagachi ✔ 6297143586 ✔C...
 
Russian ℂall gIRLS In Goa 9316020077 ℂall gIRLS Service In Goa
Russian ℂall gIRLS In Goa 9316020077 ℂall gIRLS Service In GoaRussian ℂall gIRLS In Goa 9316020077 ℂall gIRLS Service In Goa
Russian ℂall gIRLS In Goa 9316020077 ℂall gIRLS Service In Goa
 
Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...
Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...
Independent Joka Escorts ✔ 8250192130 ✔ Full Night With Room Online Booking 2...
 
VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...
VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...
VIP Model Call Girls Budhwar Peth ( Pune ) Call ON 8005736733 Starting From 5...
 
Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...
Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...
Hotel And Home Service Available Kolkata Call Girls South End Park ✔ 62971435...
 

NAFLD, NASH

  • 1.
  • 2.
  • 3. N on- A lcoholic F atty L iver D isease (NAFLD) Fatty liver (Steatosis) Steatohepatitis - inflammation - fibrosis Cirrhosis Normal liver
  • 4.
  • 5.
  • 6. NAFLD 1. Most common of all liver disorders. 2. Frequent cause of chronic liver disease. 3. Present in 3% of children and >50% of obese children. Fatty Liver Disease: NASH and Related Disorders Blackwell Publishing, 2005
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14. Pathophysiology Salgado W, et al. Acta Cir. Bras. 2006; 21.  
  • 15. Two-hit Hypothesis Fatty Liver 1 st Hit Damaged Liver 2 nd Hit Oxidative Stress Toxins Inflammatory Molecules Susceptibility Donnelly et al. J. Clin. Invest. 113: 1343, 2005 Day and James. Gastroenterol. 114: 842, 1998 Diet FFA Burned VLDL-TG
  • 16. Liver Damage 2 nd Hit Liver Damage Sat FA 2 nd Hit Apoptosis Hepatocyte Mass Fatty Liver
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37. McCullough AJ. N Engl J Med 2006; 355: 2361-3.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.