A person who is diagnosed with cancer will be offered a new alternative to chemotherapy because the traditional treatment of radiation that kills not just cancer cells but healthy human cells as well, causing hair loss, fatigue, nausea, depression, and a host of other symptoms. The application of nanorobotics can be considered as the better solution to this problems. Nanorobots are nanoelectromechanical systems designed to perform a specific task with precision at nanoscale dimensions. This technique involves the development of fully functional nanorobots capable of sensing, decision making, and actuation. From a bio inspired perspective, those in nanorobotics, including core design, propulsion and power generation, sensing, actuation, control, decision making, and system integration. The core of the nanorobots is a polysaccharide based nanoparticle, sensing and actuation ensure that it is capable of sensing and recognizing the cancer cell. These nanorobots may aid in cancer therapy, site-specific drug delivery, circulating diagnostics, advanced surgery, and tissue repair. One of the major advantages of nanorobots is it will not affect healthy cells in human body. Using strategies inspired from microorganisms, potential bioengineered nanorobots can be used for cancer therapy.
6. NanoRobots
The technology of creating machines or robots
at or close to the microscopic scale of a
nanometer (10−9 meters).
Nanorobots are devices made from DNA that
are so small they can be injected into the
bloodstream and carry a payload of drugs to
specific cells.
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7. Cure Using Nanorobots
Inject nanorobots into
patient
Detect cancer Cells
Destroy Cells
Do not affect on
Healthy Cells
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9. Nanorobot Core
The core is a polysaccharide-based nanoparticle or cyclic
peptide nanotube
Cyclic peptide has ability to self-assemble into
monodisperse nanotubes, are well suited to the core
Capable of carrying a payload
Allow the incorporation of propulsive, sensing and
actuating components
Float freely inside the body
Detect the tumor effectively
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11. Cant use conventional sources
ATP released from core
Production of heat in the human body
Inclusion of electrodes in nanorobots and
electrolytes in human blood will act as battery
Combination of chemical reactions in human
blood and chemicals in nanorobots will lead to the
formation of fuel source
Power Supply
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12. Propulsion
Fully functional flagella isolated from E.coli
Artificial bacterial flagella(ABF) to move in 3D
ABF are often fabricated from helical nanobelts with soft
magnetic heads composed of Cr/Ni/Au
It has ability to drive the nanorobots into the tumor tissue
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13. Sensing and Actuation
Capable of sensing and recognizing the targeted
cancer cells
Chemical sensors which detect the target molecules
Aptamers (derived from the latin aptus, meaning to
fit) are artificial nucleic acid (DNA or RNA)
Biomarkers can be specific cells, molecules, or genes,
gene products, enzymes, or hormones.
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14. Schematic of the cyclic peptide nanorobot core
with the aptamers designed for closing and
locking the nanotube.
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16. Control and Decision Making
Use directional control, which is necessary for tumor
targeting
Phototactic control to direct the nanorobot to the tumor
location
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17. Integration
First step is fabrication of power supply(ATP
containing nanoparticle)
Second step is load the power supply into the core
Final step is attachment of propulsion system to the
core
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18. Nanorobots can be used in blood cell to
detect pathogens.
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19. Advantages
Small Size
Inexpensive(if mass produced)
No maintenance
Automated
Painless Treatment
Easily Disposable
Affect only cancer cells
Rapid elimination of disease.
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21. Applications
Breaking up blood clots
Fighting cancer
Parasite Removal
Breaking up kidney stones
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22. Conclusion
With the introduction of nanorobots, humans can
overcome many type of diseases
It can also helpful in the detection of diseases
Decision making nanorobots are the future of
nanorobotic technology
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23. References
R. Baum, “Nanotechnology: Drexler and Smalley make the case for
and against ‘molecular assemblers’,” Chem. Eng. News, vol. 81, pp.
37–42, 2003.
M. Sitti, “Microscale and nanoscale robotics systems [grand
challenges of robotics],” IEEE Robot. Autom. Mag., vol. 14, no. 1,
pp. 53–60, Mar. 2007.
https://en.wikipedia.org/wiki/Nanorobotics
http://hansmalab.physics.ucsb.edu/phys150/nanotech.pdf
http://nano-bio.ehu.es/files/nanorobots_work.pdf
http://www.roboticsbible.com/power-sources-of-nanorobots.html
http://icmr.nic.in/ijmr/2010/august/0803.pdf
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