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CATECHU

 Synonyms     – Pale catechu, gambier, kattha
 Biological   source – It consists of the dried
 aqueous extract prepared from the leaves of
 Uncaria gambier
 Family   - Rubiaceae
 Chemical    constituents –
 It    contains   tannins     like   catechins   and
 catechu tannic acid
 It    contains flavonoids like quercetin and
 fluorescent substances Gambier fluorescein.
 It   also contains catechu- red, pyrogallol, fixed
 oil and waxes
 Uses   –
 Used   as an astringent
 Used   in the treatment of diarrhoea
 Used   in the preparation of lozenges
BLACK CATECHU

 Biological   source –
 It   consists of the dried aqueous extract
 prepared from heart wood of Acacia catechu
 and Acacia chundra
 Family   - Leguminosae
 Chemical      constituents –
 It   contains tannins like catechins and catechu
 tannic acid
 It   contains flavonoids like quercetin.
 Others      like Catechu- red and gum
 Uses    –
 Used    as an astringent, used in diarrhoea
 Used    as a cooling and digestive agent
CHEMICAL TESTS FOR CATECHU
 1.   Gambir Fluorescin test-
 Alcoholic    extract of drug, few drops of
 sodium hydroxide mix and add petroleum
 ether, shake and kept aside for few minutes
 –     petroleum   ether   layer   shows   green
 fluorescence ( + ve for pale catechu due
 Gambir Fluorescin )
 2.   Match stick test ( Catechins test) –
A     match stick is dipped in aqueous plant
 extract , dried near burner and moistened
 with Hcl. On warming near flame , the
 match stick wood turns pink or red due to
 the formation of phloroglucinol.
 3.   Vanillin – Hydrochloric acid test –
 Test    solution and few drops of Vanillin –
 Hydrochloric acid reagent – A red or pink is
 formed due the formation of phloroglucinol.
 4.   Chlorophyll test -
 Powdered     drug is heated with chloroform on a
 water bath for 1-2 minutes .The organic layer
 is filtered in a china dish and evaporated on
 the water bath– green residue
TANNIC ACID
 Biological   source –

   It is obtained from the nutgalls. Galls are
 vegetable outgrowths found on the young
 twigs of Quercus infectoria
 Family   - Fagaceae
 Tannic   acid is a hydrolysable tannin and
 yields Gallic acid and glucose on hydrolysis
 Uses   –
 Used   as an astringent
 Used   externally in the treatment of burns
 Used   as an antidote for alkaloid poisoning
NUTGALL
 Synonym      – Turkey galls
 Biological   source – Galls are the pathological
 outgrowths formed on           the twigs of the oak
 tree Quercus infectoria
 Family   - Fagaceae
 Chemical     constituents – 40-60% of tannic acid
 Uses-   Used as an astringent, used in the
 manufacture of tannic acid
   QUESTIONS –

 Define   tannins and explain various methods of estimation
    of tannins.10 M
 Write   a note on general properties and method of isolation
    of tannins. 10M
 Write   the source, active constituents and uses of Catechu
    and Nutgall.5M
 Explain   the different types of tannins with examples.5M
 Write   a note on Goldbeaters’ test and its significances.5M
 Write   a note on estimation of Hydrolysable tannins.5M
 Give    the chemical tests for the identification of Catechu
  and Tannic acid.5M
 Give    an account of Catechu.5M
 What    are tannins? Give general chemical tests to identify
  them.5M
 Define    Tannins. How will you differentiate True tannins
  from pseudo tannins ? 5M
 Write   in brief about Nut gall. 2M
 Chemical    tests for the identification of tannins.2M
 What    is tannic acid and give its uses.2M
 Gambir-    Flurorescin test and its significances.2M
 Define    Pseudo- tannins and give examples. 2M
Tannins   drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

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Tannins drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

  • 1.
  • 2. CATECHU  Synonyms – Pale catechu, gambier, kattha  Biological source – It consists of the dried aqueous extract prepared from the leaves of Uncaria gambier  Family - Rubiaceae
  • 3.  Chemical constituents –  It contains tannins like catechins and catechu tannic acid  It contains flavonoids like quercetin and fluorescent substances Gambier fluorescein.  It also contains catechu- red, pyrogallol, fixed oil and waxes
  • 4.  Uses –  Used as an astringent  Used in the treatment of diarrhoea  Used in the preparation of lozenges
  • 5. BLACK CATECHU  Biological source –  It consists of the dried aqueous extract prepared from heart wood of Acacia catechu and Acacia chundra  Family - Leguminosae
  • 6.  Chemical constituents –  It contains tannins like catechins and catechu tannic acid  It contains flavonoids like quercetin.  Others like Catechu- red and gum  Uses –  Used as an astringent, used in diarrhoea  Used as a cooling and digestive agent
  • 7. CHEMICAL TESTS FOR CATECHU  1. Gambir Fluorescin test-  Alcoholic extract of drug, few drops of sodium hydroxide mix and add petroleum ether, shake and kept aside for few minutes – petroleum ether layer shows green fluorescence ( + ve for pale catechu due Gambir Fluorescin )
  • 8.  2. Match stick test ( Catechins test) – A match stick is dipped in aqueous plant extract , dried near burner and moistened with Hcl. On warming near flame , the match stick wood turns pink or red due to the formation of phloroglucinol.
  • 9.  3. Vanillin – Hydrochloric acid test –  Test solution and few drops of Vanillin – Hydrochloric acid reagent – A red or pink is formed due the formation of phloroglucinol.  4. Chlorophyll test -  Powdered drug is heated with chloroform on a water bath for 1-2 minutes .The organic layer is filtered in a china dish and evaporated on the water bath– green residue
  • 10. TANNIC ACID  Biological source – It is obtained from the nutgalls. Galls are vegetable outgrowths found on the young twigs of Quercus infectoria  Family - Fagaceae  Tannic acid is a hydrolysable tannin and yields Gallic acid and glucose on hydrolysis
  • 11.  Uses –  Used as an astringent  Used externally in the treatment of burns  Used as an antidote for alkaloid poisoning
  • 12. NUTGALL  Synonym – Turkey galls  Biological source – Galls are the pathological outgrowths formed on the twigs of the oak tree Quercus infectoria  Family - Fagaceae  Chemical constituents – 40-60% of tannic acid  Uses- Used as an astringent, used in the manufacture of tannic acid
  • 13. QUESTIONS –  Define tannins and explain various methods of estimation of tannins.10 M  Write a note on general properties and method of isolation of tannins. 10M  Write the source, active constituents and uses of Catechu and Nutgall.5M  Explain the different types of tannins with examples.5M  Write a note on Goldbeaters’ test and its significances.5M
  • 14.  Write a note on estimation of Hydrolysable tannins.5M  Give the chemical tests for the identification of Catechu and Tannic acid.5M  Give an account of Catechu.5M  What are tannins? Give general chemical tests to identify them.5M  Define Tannins. How will you differentiate True tannins from pseudo tannins ? 5M
  • 15.  Write in brief about Nut gall. 2M  Chemical tests for the identification of tannins.2M  What is tannic acid and give its uses.2M  Gambir- Flurorescin test and its significances.2M  Define Pseudo- tannins and give examples. 2M