SlideShare una empresa de Scribd logo
1 de 133
Descargar para leer sin conexión
Valeant: An Enduring
Engine for Growth
December 16, 2015
1
Forward-looking Statements
Forward-looking Statements
Certain statements made in this presentation may constitute forward-looking statements,
including, but not limited to, statements regarding guidance with respect to expected
revenues, non-GAAP cash earnings per share, adjusted cash flows from operations and
organic product sales growth, future disclosures, launches and approvals of products,
business development activities, and the 2016 strategic initiatives of Valeant Pharmaceuticals
International, Inc. (the “Company”). Forward-looking statements may be identified by the use
of the words “anticipates,” “expects,” “intends,” “plans,” “could,” “should,” “would,” “may,”
“will,” “believes,” “estimates,” “seeks,” “potential,” or “continue” and variations or similar
expressions. These statements are based upon the current expectations and beliefs of
management, and depend on assumptions, data or methods that may be incorrect or
imprecise and are subject to certain risks and uncertainties that could cause actual results to
differ materially from those described in the forward-looking statements. These risks and
uncertainties include, but are not limited to, risks and uncertainties discussed in the
Company's most recent annual or quarterly report filed with the Securities and Exchange
Commission ("SEC") and other risks and uncertainties detailed from time to time in the
Company's filings with the SEC and the Canadian Securities Administrators ("CSA"), which
factors are incorporated herein by reference. Readers are cautioned not to place undue
reliance on any of these forward-looking statements. The Company undertakes no obligation
to update any of these forward-looking statements to reflect events or circumstances after
the date of this presentation or to reflect actual outcomes.
Note 1: The guidance in this presentation is only effective as of the date given,
December 15, 2015, and will not be updated or affirmed unless and until the Company
publicly announces updated or affirmed guidance.
2
J. Michael Pearson
Chairman and CEO
<portrait>
3
Drivers of Valeant’s success
Our decentralized model and talented people, which give
us a competitive edge (speed of decision making and in-
depth customer knowledge)
Our collection of great healthcare brands around the
world
Our innovative strategies (often disruptive), which have
challenged industry convention
Our relentless focus on providing easy and affordable
access for physicians and patients
Our exceptionally productive approach to R&D
4
A collection of great brands in a breadth of
therapeutic areas
Valeant 2016 forecast revenues
19%
21%
Gastrointestinal (GI)
17%
Emerging
markets (including
Ophthalmology,
Dermatology,
and GI sales)
22%
Ophthalmology and
Eye Care (B+L)
Dermatology and
Skin Care22%
Oncology, Dentistry,
Women’s Health,
Neuro and Other
Total: $12.5 – 12.7 B
5
Dermatology
▪ Great brands in attractive segments
▪ Importance of trust-based physician
relationships
▪ Concentrated, specialist prescriber base
▪ Attractive from a payor standpoint
– High component of cash pay
– Reasonably priced products
▪ Lower-cost, lower risk R&D
4-year mkt CAGR: ~5%
6
▪ Strong underlying global growth
drivers (e.g., demographics)
▪ Attractive specialty Rx and OTC segments
▪ Importance of trust-based physician
relationships
▪ Concentrated, specialist prescriber base
▪ Significant unmet medical needs
▪ Opportunity for lower-risk innovation
▪ Low exposure to reimbursement pressure;
significant cash pay
▪ Durable products
4-year mkt CAGR: ~6%
Ophthalmology (B+L)
7
Gastrointestinal
▪ Concentrated, specialist prescriber
population
▪ Importance of trust-based physician
relationships
▪ Concentrated, specialist prescriber base
▪ Less of a priority for many larger pharma
companies
▪ Favorable reimbursement
▪ Opportunity for low-risk, incremental
innovation
8
Emerging markets
▪ 1,000+ brands with sales in
emerging markets
▪ High growth markets (e.g., Mexico,
China, Middle East / North Africa)
▪ Rich pipeline of upcoming launches
▪ Decentralized operating model
▪ Products not dependent on
reimbursement
▪ Local R&D capabilities
4-year mkt CAGR: ~7%
9
Valeant Access Program with Walgreens –
Physician/Pharmacist/Patient-led experience
▪ Direct distribution to patients through
Walgreens
▪ All products in Walgreens on
consignment; Walgreens never takes title
▪ Walgreens paid a distribution and
pharmacy fulfillment fee
▪ Valeant sets prices to the patient
▪ Ensures affordable, immediate access to
all Valeant brands in program that
physicians prescribe (for eligible patients)
Branded Access
Program
Branded Generic
Access Program
10
Our innovative strategies – the early years
▪ Dramatically
reduced OPEX
(e.g., to focus
predominantly on
customer-facing
areas)
▪ Shifted from high-
risk/high-spend
R&D (e.g.
neurology,
virology) to lower
cost “singles and
doubles”
▪ Built unrivaled
M&A capabilities
(e.g., requiring
returns in excess of
cost of capital)
▪ Began building
undervalued
BGx and OTC
businesses
(e.g., in
emerging
markets)
▪ Initiated new
R&D capability
and operating
model (e.g.,
Dow)
▪ Executed
merger of
equals with
Biovail (strong
strategic fit,
improved tax
rate)
2008 2009 2010
▪ ~$600M in revenue
▪ 8% operating margin
and 1% growth
▪ Imminent Effudex generics
▪ Bloated cost base and
infrastructure
▪ High risk, high spend R&D
▪ Demotivated organization
Then
11
Our innovative strategies – recent years
▪ Gained critical
mass in
ophthalmology
with acquisition
of B+L
▪ New R&D model
beginning to
pay dividends
▪ Created
attractive
access program
in dermatology
initially through
partnership with
Philidor
▪ Built a leading
US market
position in
dermatology,
with a series
of focused
acquisitions
(e.g., Medicis,
Obagi,
Dermik/Ortho)
▪ Secured entry into
attractive GI space with
acquisition of Salix
▪ Created even better,
branded access
program with Walgreens
▪ Launched with
Walgreens the first
branded generics
program in the US
2011
/12
2013
/14
2015
▪ $12.5-12.7B in revenue
▪ Double-digit organic
growth
▪ Great brands around
the world
▪ Attractive geographies
and TA platforms
▪ Energized and
committed talent base
Now
12
Our R&D model
Rx R&D spend
as a % of
branded Rx
sales
8%
▪ 6 NDAs approved in last 3 years
▪ 200+ active US programs
▪ Dermatology Phase II and
Phase III success rates 3-5x
better than industry averages
▪ Highest 5 year output1 on R&D
spend in the industry
1 Number of NMEs/BLAs approved 2009-'14 for each $1 billion spent;
peer set is 15 companies with the highest number of NME/BLA approvals
13
Our decentralized model
▪ Empowers local leaders to make decisions that are right
for their business
▪ Allows us to move with speed and agility
▪ Aligns with our customers’ needs
▪ Ensures strong centralization and controls in key
functions/ activities, e.g.,
– Finance
– Compliance
– Audit
– Pharmacovigilance
14
How you can measure our progress in 2016
▪ Retained all key management talent and added
new key hires
▪ Dermatology returned to growth
▪ Maximized Xifaxan – created our first $1B brand
▪ Got approval and successfully launched
– Brodalumab
– Latanoprostene Bunod
– Relistor Oral
▪ Delivered $100-150M in addyi sales in 2016
▪ Brought leverage to ~4.0x by end of 2016
15
Who you will hear from – Our business leaders
Yang Yang
BU Director,
Vision Care China & Japan
Fernando Zarate
GM, Mexico, Andean region,
Central America and
Caribbean
Joe Gordon
SVP and GM,
Consumer Health Care
Deb Jorn
EVP, Dermatology and GI
Dr. Tage Ramakrishna
Chief Medical Officer, Head of
R&D and Quality
Robert Rosiello
EVP, CFO
Tracy Valorie
SVP and GM, Women’s Health
and Bausch + Lomb
Pharmaceutical Division
Mark McKenna
VP and GM,
Bausch + Lomb
16
Robert Rosiello
Executive VP, CFO
<portrait>
Financial guidance
17
* Non-GAAP (see Appendix)
Previous Q4
2015
Guidance
Revised Q4
2015
Guidance
~$3.25 - $3.45B ~$2.7 - $2.8B
~$4.00 - $4.20
per share
~$2.55 - $2.65
per share
>$1.0B >$600M
Revenue
Adjusted EPS*
Adj. Cash
Flow from
Operations*
Revised Q4 2015 and full-year 2015 guidance
18
Midpoint of previous guidance
Midpoint of revised guidance
~$3,350M ~$4.10
Revenue
Adjusted
EPS*
Philidor separation
Estimated one-time revenue impact from
Walgreens transition
Pricing and volume-related changes (e.g., non-
promoted products)
~($250M)
~($150M)
~($200M)
~($0.65)
~($0.40)
~($0.45)
~$2,750M ~$2.60
* Non-GAAP (see Appendix)
Bridge from previous Q4 2015 guidance
19
Estimated Q4 Revenue Impact: (~$250M)
 Announced Philidor separation October 30
 Provided free scripts from October 31 to November 8
 Dispensed refills without seeking reimbursement from payors
from November 9 to present
 Average cash pay price declined from $67 to $23
 Lost ~20% of scripts from business disruption in Q4, virtually all
Philidor covered scripts
Philidor separation
20
 Transition to consignment model at Walgreens for
current inventory on hand
 Under this arrangement, Valeant will hold title to products
sold under this program until dispensed to a patient
 Valeant will credit Walgreens for any inventory on hand in
its stores or distribution centers as part of transition
 Estimated reduction in traditional channel
inventories for the products included in Walgreens
program
One-time revenue impact from Walgreens transition
21
2016 Guidance
~$12.5B – 12.7B
~$13.25 – 13.75
per share
~$6.9 – 7.1B
Revenue
Adj. EPS*
Adj. EBITDA*
* Non-GAAP (see Appendix)
2016 guidance
22
Previous 2016 Adj. EBITDA* Outlook
2016 Adj. EBITDA* Guidance (Mid-point)
>$7.50B
Dermatology Patient Access Program ramp-up ~($225M)
~$7.0B
Changes in pricing assumptions ~($125M)
Employee retention bonuses ~($75M)
Incremental legal fees ~($75M)
* Non-GAAP (see Appendix)
Bridge from previous 2016 EBITDA outlook
23
Revised 2015
Guidance
2016
Guidance
2016
Guidance %
over Updated
2015
Guidance
$10.4B – 10.5B ~$12.5B – 12.7B ~21%
Double-Digit Double-Digit NA
$10.23 – 10.33
per share
~$13.25 – 13.75
per share
~31%
>$5.4B $6.9 – 7.1B ~30%
Revenue
Organic Growth*
Adj. EPS*
Adj. EBITDA*
* Non-GAAP (see Appendix)
2016 guidance vs. revised 2015 guidance
24
 Exchange rates based on current spot rates
 No use of balance sheet/acquisitions
 Planned impact from generics expected ~($140M) in revenues
 Glumetza (Q1); Zegerid (Q3); Nitropress (Q4); Virazole (Q4)
 No use of balance sheet/acquisitions
 U.S. branded drugs (excluding drugs in the Walgreens program) consistent
with PBM, managed care contracts
 Other U.S. businesses (e.g., contact lenses, consumer) typically no more
than CPI
 Ex-U.S. driven by volume, pricing impact is immaterial
 Negotiated price discounts for hospital-administered drugs of ~30% (e.g.,
Nitropress, Isuprel, Virazole, Ammunol)
 COGS* ~20-21%
 SG&A* ~23-24%
 R&D spend ~$400-500M
* Non-GAAP (see Appendix)
2016 guidance assumptions (1/2)
25
 Restructuring charges expected <$200M
 Higher charges in Q1 and Q2 due to completion of restructuring and
integration programs for Salix, Sprout, Synergetics, Amoun, trending
downward in Q3 and Q4
 Cash tax rate expected to be ~5%
 Interest expense ~$1.6B
 Sequential quarters for Revenue and Adjusted EPS* are expected to be higher
than the previous quarter
 2H will be substantially higher than 1H due to ramp up in Walgreen’s
programs
 Cash Flow Items
 Cap Ex - ~$350M
 Depreciation - ~$200M
 Stock Based Comp - ~$200M (includes impact of employee retention
plan)
2016 guidance assumptions (2/2)
* Non-GAAP (see Appendix)
26
Q1 2016
Guidance
$2.8 - $3.1B
$2.35 - $2.55
per share
 Dermatology Patient Access Program ramp-up
 Continued impact of reduction in channel inventories
Revenue
Adj. EPS*
Q1 2016 guidance
* Non-GAAP (see Appendix)
27
 Majority of 2016 free cash flow used for debt pay down
 Committed to minimum debt pay down in 2016 of >$2.25B including
$562M term loan amortization and $260M maturities
 Remain in clear compliance with credit agreement financial maintenance
covenants
 Senior secured leverage covenant: 2.5x (secured debt to pro forma
adjusted EBITDA*)
 Interest coverage covenant: 2.25x though March 31, 2016, then 3.0x (pro
forma adjusted EBITDA* to pro forma interest coverage)
 Net leverage to pro forma adjusted EBITDA* expected to be ~4x by year end
 Minimal amortization and maturities until 2018
 2016: $822M
 2017: $631M
 2018: $2,923M + $1,500M (Revolver)
* Non-GAAP (see Appendix)
Balance sheet update
28
 Cash flow
 “Adjusted cash flow from operations” and “Cash conversion” will no
longer be reported each quarter
 Only GAAP Cash Flow will be reported going forward
 We will continue to report integration expenses by acquisition on
quarterly basis so investors can continue to calculate adjusted cash
flow, if desired
 Adjusted EBITDA* will be reported on a quarterly basis
 “Cash EPS” to be labeled “Adjusted EPS* (non-GAAP)”
 Top 30 global brands
 Volume and Price/Mix for total company and U.S. branded Rx business
* Non-GAAP (see Appendix)
Changes to planned quarterly disclosures
29
Deb Jorn: EVP, Dermatology and GI
Background
▪ 30+ years in Pharma industry
▪ Bausch + Lomb; VP and CMO (3 years)
▪ Schering-Plough (5+ years)
– VP for Women’s Healthcare and Fertility
– VP for Allergy, Respiratory, and Urology
▪ J&J (2 years)
– VP for Internal Medicine
▪ Pharmacia Corporation (2 years)
– VP for Detrol / Detrusitol and Urology
▪ Merck (20 years)
– Executive Director, Worldwide Human Health Marketing;
Respiratory Products; senior marketing roles
Education
▪ M.B.A., NYU Stern Graduate School of Business
Administration
▪ B.A., Rutgers University
30
Jublia
31
Onexton
32
Key Takeaways
• Valeant is the #1 Medical Dermatology Company1 in
the U.S.
• Internal R&D efforts resulted in approval of 4 new
products in 2014 (Jublia, Onexton, RAM .08, Luzu)
• Strong near-term pipeline expected to sustain organic
growth
• Deep, trust-based relationships with dermatologists and
podiatrists
• New Valeant Access Program, in partnership with
Walgreens, launching in January 2016
Source: Symphony Monthly PHAST Audit MAT October 2015
1. Excluding biologics and oral antibiotics
*Dermatology Rx refers to entire USC2 37000 (Dermatological, Ethical)
**Sales are based on MBS Dollar Sales (MBS represents a standardized dollar
metric based on manufacturer’s published catalog or list prices to wholesalers
33
Oct 30th 2015 – Nov 8th 2015
 No submission of claims to
payors after October 30th
 All prescriptions filled at no
cost to patient
 Commercial insured and
uninsured only – no
government plans
3 phase transition plan
Phase I:
Initial Transition
 Rapidly developed new
access program
 Entered into agreement
with Walgreens
 Prepared for execution
with excellence
Nov 9th 2015 until new
program in place (before
Jan 30th 2016 Philidor
closing)
 $35 cash pay option for
all new and refill
prescriptions sent to
Philidor
 Refills already in Philidor
prior to Nov 9th filled for
$0 if previous refill was
that copay or $35
 Commercial insured and
uninsured only – no
government plans
Phase II:
Full Transition
Phase III:
Relaunch
34
Key recent actions
Customer outreach
 20 cities covered in 6 weeks by senior
management and sales & marketing team
 Reaffirmed commitment to Dermatology /
Podiatry specialty
Retention
 Retained all sales & marketing leaders
 Retained all but two sales representatives out
of field force of over 350
 Maintained historic vacancy rate of 5% (lower
than industry norms)
New Access Program
 Gathered input regarding key elements of new
access program
 Established new relationship with leading
consumer retailer (Walgreens), streamlining
prescription process for patients and physicians
35
We have retained 81% of dermatology prescriptions
-
20,000
40,000
60,000
80,000
100,000
120,000
140,000
Pre Post
Covered
Uncovered
Cash
Retail
1 October average pre Philidor
2 November average, excluding Thanksgiving week post Philidor
1 2
# of weekly TRx
▪ Retail prescriptions
grew by 17% to 66,000,
mitigating overall drop
in total prescriptions
~116,000
~94,000
+17%
Philidor
36
Valeant’s new access program
▪ Ensures affordable, convenient patient access
to medicines prescribed by their physician1
▪ Some products as low as $0
▪ Allows physicians, NPs and PAs to focus their
efforts on patient care
▪ Sales force will start providing physicians with
program overview as of Dec 21st
▪ Goal: fully operational January 15th
1 Commercial insured and uninsured only – no government plans
2
37
New access program is simpler for patients and
physicians
New Approach
HCP sends
Rx to Walgreens
Patient picks up
Rx at Walgreens
same day
Old Approach
HCP sends
Rx to Philidor
Patient calls Philidor
with insurance, credit card
2-3 days later Rx
arrives at home
38
9/14 YTD 9/15 YTDQ3 YTD
2014
Q3 YTD
2015
Strong Organic Growth in Dermatology
Valeant Dermatology Revenues
1 Brands launched 2014+: Luzu (Q2 14), Jublia (Q3 14), Ram08 (Q3 14), and Onexton (Q1 15)
$1,266M
$718M
0
20
40
60
80
100
120
140
160
Q2
2014
Q3
2014
Q4
2014
Q1
2015
Q2
2015
Q3
2015
New Product Revenue1
$150M/quarter
76%
In-line brandLaunch brand1
Total Revenue
39
Exciting Late-stage Dermatology Pipeline
2017+
IDP – 121 (acne vulgaris)
2016
Brodalumab (plaque
psoriasis)
IDP – 122 (plaque psoriasis)
IDP – 118 (plaque psoriasis)
IDP – 120 (acne vulgaris)
Select pipeline products
40
Gastrointestinal health
41
Gut GuyTM
Hepatic Encephalopathy (HE) Irritable Bowl Syndrome – diarrhea (IBS-D)
Xifaxan 550mg
42
TV
PRINT
DIGITAL
75
55
80
65
50
85
70
60
Oct-
15
Oct-
14
Jul-
14
Apr-
15
Jan-
15
Jul-
15
IBS-D indication Drives Xifaxan TRx Growth
*Note: TRx’s are Unit-adjusted each month based on the different Pack Sizes of 42 and 60
Source: Symphony PHAST 2.0
IBS-D
Indication
Retail + Hospital TRx’s*
DTC
Launch
Thousands of
Xifaxan scripts
(US)
+27%
TRx
81K Rx /
month
64K Rx /
month
43
 Up to 8M in US at risk for Chronic Liver Disease1, including those
with Overt HE
 Only 2 products are approved for Overt HE: lactulose and Xifaxan
 2014 AASLD/EASL Guidelines recommended the addition of
Xifaxan to lactulose to maintain Overt HE remission, which has
been shown to reduce risk of Overt HE recurrence by 58% and
hospitalizations by 50%2
 Today only 45% of NRx for Lactulose are written with Xifaxan,
creating a large untapped opportunity for Xifaxan to help HE
patients
Xifaxan continues to have substantial growth potential
in hepatic encephalopathy (HE)
1 Includes patients with HepB, HepC, NAFLD, NSH, and OHE; source: National Institute of Diabetes and Digestive and Kidney Disease.
Digestive Diseases Statistics for the United States. Assessed September 7, 2010
2 Bass NM, Mullen KD, Sanyal A, et al. Rifaxamin treatment in hepatic encephalopathy. N Engl Med. 2010;362(12):1071-1081
44
 Increase sales force by a further 100 representatives to
support Xifaxan growth in HE
 Expand the GI team in high density areas
 Increase continuity of care between sales teams working in
hospitals and out-patient settings
Key actions to accelerate Xifaxan growth
45
Strong growth of in-line brands
Source: Symphony PHAST 2.0 + VA Procurement, Non-Retail TRx’s are unit-adjusted each month based on the different Pack Sizes of 42 and 60
* Since Ruconest Launched in Dec 2014, Growth Rates are 5 vs. 5 months (instead of 12 vs. 12 months).
Brand
% TRx
Growth
YOY October
Apriso 8%
Uceris 30%
Relistor 33%
Ruconest* 140%
46
 An estimated 3% of the adults in the US are receiving long-
term opioid therapy
 41% of those patients, or approximately 3.7 million patients,
develop Opioid Induced Constipation (OIC)
 The prescription market for OIC is growing rapidly now that
there is an oral option
 In our phase III program, Relistor oral significantly increased the
percentage of patients with a rescue-free bowel movement
(RFBM) within 4 hours
Relistor Oral (April 19, 2016 PDUFA)
Source: Spencer Dorn, et al. American Journal of GASTROENTEROLOGY 2014
47
Strong Late-stage GI Pipeline
2017+2015
Xifaxan
IBS-D
SAL-023
Chronic cirrhosis of liver
2016
Relistor Oral
Opiod induced constipation
SAL-024
Crohn's
SAL-022
Diabetes
SAL -021
Rheumatoid arthritis
SAL-020
Hereditary angioedema
Select pipeline products and launches

48
Tracy Valorie: SVP and GM, Women’s Health and B+L
Pharmaceutical Ophthalmology
Background
Education
▪ 20+ years in Pharma industry
▪ Bausch + Lomb
– Vice President of Pharmaceutical Marketing
– Former Global Head of Glaucoma
▪ Pfizer
– Global Commercial Lead of Ophthalmology
(Xalabrands and Macugen), mid-stage development
portfolio, and long-range planning
▪ Experience in discovery, clinical development, commercial
assessment, marketing and strategic planning
▪ Previous board membership The Glaucoma Foundation
and ARVO Foundation for Eye Research (AFER)
▪ M.B.A., Rensselaer Polytechnic Institute
▪ B.S. Molecular Biology, University of Connecticut
49
addyi is a breakthrough product with great potential
▪ addyi is the first FDA approved product for Hypoactive Sexual Dysfunction
Disorder (HSDD) in premenopausal women and is not the “Female Viagra”
▪ Hypoactive Sexual Dysfunction Disorder effects many premenopausal
women
– ~15M premenopausal women have HSDD
– Only 10% diagnosed
– Opportunity to educate on the disease state and expand the diagnosed
population
▪ Physician and Patient Education, and managing expectations is critical to
success, including:
– Education on disease state
– Physician and patient education on features, benefits, and risks of addyi
50
Challenge ahead of us: TRx’s are not being filled
Source: McKesson
0
1000
2000
3000
4000
5000
6000
7000
8000
Oct-23 Oct-30 Nov-06 Nov-13 Nov-20 Nov-27 Dec-04 Dec-11
addyi TRx (# TRx cumulative)
TRx filled
Total TRx
-82%
51
Physician sentiment is positive
“
”
Physicians are optimistic
about addyi as an FDA
approved treatment
option
”
It is fantastic that we have an FDA-
approved medication for a woman with a
sexual health concern… I did not think this
was possible prior to this day and age
“
”
We discuss and write scripts for multiple
patients in our clinic every day
Physicians who have
experience with addyi are
enthusiastic about its
potential
Physicians caution that
managing expectations is
crucial
“
Physicians need to be educated on the
disease state and the product so they can
appropriately counsel patients on how the
product works and what they can expect
Source: Symphony, RelayHealth as of Dec. 2015, physician outreach
“
”
52
We have a strong assessment of the issues
▪ Limited physician education /
awareness of HSDD and addyi
▪ Confusion around REMS certification
process (physicians and pharmacies)
▪ Sales force targeting not optimal
53
Go forward plan
▪ Remove barriers to REMS certification
▪ Physician and patient outreach, MSL recruiting
and training
▪ Build an integrated Valeant team (Commercial,
Medical, Sales, etc.)
▪ Improve field force effectiveness
– Revisit targeting and call plan
– Improve reach and frequency on key targets
– Retrain our sales force
– Enhance performance management
▪ Improve patient access (thru Walgreens Access
Program as of Jan. 15th)
54
Market Access: Continuing to improve
▪ 50% of US lives are covered to date
▪ >1/3 of all US lives have unrestricted coverage
▪ Managed Markets team is working diligently
with our payor stakeholders to improve accessUnrestricted
coverage
Restricted
coverage
50%
U.S. lives
covered
Seeking
coverage /
under
negotiation
35%
15%
55
addyi: 2016 Expectations
USD 100-150M+
net revenue
56
Mark McKenna: Vice President and General Manager,
Bausch + Lomb
Background
▪ 13+ Years of diverse experience in the eye health category in
leadership roles across sales, marketing, operations and strategy
▪ Led the reinvigoration of the U.S. contact lens product portfolio,
making Bausch + Lomb the fastest growing contact lens
company in the U.S.
▪ Held positions of increasing responsibility in Bausch + Lomb’s
sales and marketing division, most recently as Head of Sales and
Operations
▪ Global Marketing experience leading new product
development projects for Bausch + Lomb from ideation through
commercialization
▪ Joined Bausch + Lomb in 2006 after spending several years with
Johnson & Johnson Vision Care
▪ Speaker at the 5th Annual Life Science Executive Leadership forum
Education
▪ MBA from Azusa Pacific University
▪ BA in Marketing from Arizona State University
57
Biotrue lens
58
The resurgence of an iconic eye care brand
▪ Valeant has transformed the underperforming Bausch + Lomb
(B+L) company into a $1.2B+ diversified vision care business
▪ Products are outgrowing category averages through
commercial investments in the US and a decentralized model
▪ Global roll out of contact lens pipeline, which will build on US
and Asia success
▪ One of the fastest growing contact lens solution brands in the
world
▪ Strong pipeline, with >20 product launches and extensions
planned for next 3 years globally
59
B+L contact lens business turnaround under Valeant
US B+L contact lens revenue and
growth in millions
▪ Innovation and Organic Growth: Our
investments in R&D, DTC marketing
and manufacturing have allowed us
to drive organic growth in vision care
▪ Distinctive Commercial Model: Our
physician oriented approach has
enabled us to transform Biotrue®
ONEday into one of the fastest
growing daily disposable brands
20% lens CAGR under Valeant
ownership vs 5% lens category CAGR1
$-
$50
$100
$150
$200
$250
$300
2009 2010 2011 2012 2013 2014 2015 2016
-1%
-7% -2%
-8%
-8%
+16%
+26%
+26%
Source: Management estimates, 3rd party data
1 Category CAGR over same time period
Annual
growth
E
60
B+L is growing rapidly relative to competitors
Source: 3rd party data, Company filings
Lens sales growth
2013-’15
6%
Market
Average1 5%
-3%
22%
7%
1 B+L and top market competitors
2 Excludes private label sales
Solutions sales growth
2013-’15
-1%
-5%
0%
7%
All others2
2%
Market
Average1
61
Winning Strategies for Contact Lenses
• Expanded Sales Force by 50% to increase frequency and reach
• Signed multi-year partnership agreements with leading optical
retailers; Vision Source (#2) and NVI (#4)
• Accelerated Bausch + Lomb ULTRA Multifocal & Toric launches
by 12 months
20%+
Annual
Growth
Next
3 Years
• Upgraded organization with top industry talent
• Formed Professional Strategy group to enhance peer-to-peer
outreach
• Innovative launch strategies to maximize launch trajectory
Forge Higher Performance Leadership Team
Enhance Operational Effectiveness
Strengthen Customer Partnerships
Launch Excellence
Accelerate the Pipeline
62
Bausch + Lomb ULTRA® is Fastest Growing
Frequent Replacement Contact Lens
 Sales: Forecasted to more than
double from $45M in 2015 to
$100M+ in 2016
 Share: Unprecedented 7.9 share
within 18 months of launch
 Distribution: Gained +13k
doorways in 2015 resulting in 22k
total ECP’s1 with diagnostic
fitting sets
 DTC Campaign: Delivered over
1B impressions via Digital, Social,
and Paid Search in 2015, and TV
spots planned for first half of
20160
1
2
3
4
5
6
7
8
9
ULTRA share of dollars in FRP category
1 Eye care professionals
Source: 3rd party data, Management Estimates
Marketshare(%)
63
Bausch + Lomb ULTRA®
64
Bausch + Lomb ULTRA, a CLEAR standout in recent
Eye Care Professional poll
Cleveland Research Company, Nov 2015
34%
22%
19%
15%
7%
3%0%
10%
20%
30%
40%
ULTRA Clariti
Freshday
MOIST for
Presbyopia
Acuvue
OASYS One
Day
Air Optix
Colors
MyDay
When ECP’s Were Asked:
Which recently launched lens has gained
the most traction in your practice?
65
Bausch + Lomb ULTRA® 2016 Launch Activities
Launching Bausch + Lomb ULTRA® for
Presbyopia and Astigmatism in 2016
 Expand Bausch + Lomb ULTRA® reach by 35%
of the market (multifocal and toric)
 Halo effect on Spherical business
Investing Multi-Million Dollar in DTC campaign
 TV, Digital, Social Media, Search
 In-office Digital Displays to create 360
campaign
Targeted Professional Outreach
 Largest Eye Care Professional Share of Voice
within contact lens industry
 High impact launch events to generate
awareness and request of new products
66
Biotrue® ONEday is one of the fastest growing daily
disposable brands through a change in go-to-market strategy
US Biotrue ONEday net sales since acquisition
0
1
2
3
4
5
6
7
8
9
Q3 '13 Q4 '13 Q1 '14 Q2 '14 Q3 '14 Q4 '14 Q1 '15 Q2 '15 Q3 '15
Base trend
Biotrue
ONEday is
on track to
achieve a
60% YOY
growth rate
in 2015
Sales($M)
67
New Product Launches Planned Over the Next
Years Across Lens and Lens Care
13
3
2015 2016
Q2 Q3 Q4Q1
2017 - 2020
BLC-009
(Astigmatism)
 Biotrue Multifocal
BLC-007 (Multifocal)
BLC-008
(Astigmatism)
BLO-030
(Disinfectant)
▪ BLC-003 (single vision spherical /
multifocal / astigmatism)
▪ BLC-005 (single vision
spherical / multifocal)
▪ BLC-001 (single vision
spherical)
▪ BLC-006 (single vision spherical)
▪ BLC-002 (cosmetic single vision
spherical)
▪ BLC-004 (Novel Astigmatism)
▪ BLO-027 (Lubricant)
▪ BLO-028 (Lubricant)
▪ BLO-029 (Disinfectant)
Select product pipeline and launches
68
Yang Yang: Business Unit Director, Vision Care China & Japan
Background
▪ 15+ years China and overseas consumer marketing & sales
experience. Born and raised in Beijing, China
▪ Bausch + Lomb / Valeant (China & Japan)
- Business Unit Director – Vision Care
- Marketing Director – Vision Care
▪ L'Oréal (China)
- Director of e-commerce – L'Oréal Paris, Maybelline, & Garnier
- Marketing Director – Garnier
▪ Johnson & Johnson Consumer Products
- Marketing Manager – Listerine, Carefree, & o.b. (China)
- Brand Manager – Reach & Visine (USA)
▪ Citigroup CitiCards – New Product Development (USA)
▪ Procter & Gamble (China)
- Category Management Manager
- Key Account Manager & Unit Manager
Education
▪ MBA, University of Michigan, Ross School of Business
▪ BA English Language & Literature, Peking University
69
Valeant China
70
Vision care is growing strongly in Asia
Japan
Korea
Thailand
Hong Kong
Singapore
India
China
Taiwan
Malaysia
Vision care sales
$491 million (2015)
+6% annual growth
71
Valeant China business overview
15%Rx Vision Care45%
25%
Surgical
15%
OTC eye drop
▪ 1st contact lens
company to enter
China; the brand
name has been used
as synonym for
contact lens
▪ B+L is the #1
recognized brand in
China and preferred
by consumers
▪ B+L is also the #1
vision care brand in
China, with fastest
growth
Valeant China business by franchise 2015
Total China sales: $ 277M
72
2014 China lens market by modality
revenue & % growth: ~$284M, +3%
2014 China vision care market
revenue & % growth: ~$438M, +2%
44%
21%
35%
Lens care
24%
22%
54%
Clear lens DailyHalf yearly / Yearly MonthlyCosmetic lens
+4%
+1%
+1%
+2%
-3%
+15%
China Market – All companies
NOTE: USD at constant dollars
Source: CLI, credit report and trade intelligence
China is a half yearly / yearly lens market;
cosmetic lens is 1/3 of total lens market
73
B+L is the #1 and the fastest growing vision care
brand in China
Source: CLI, credit report, and trade intelligence
2013-’14 growth rate
%
Revenue 2014
$M
$125
$105
$57
$49
$8
$438
Market Share 2014
%
28%
24%
13%
11%
2%
100%
16
9
8
-6
-26
2Total
74
2012
$M
2015
$M
Growth
%
Clear lens 46 63 +37%
Cosmetic lens 12 28 +131%
Lens care 21 35 +61%
Total vision care 79 125 +58%
Growth is driven by all three segments
China vision care business
75
46
49
54
63
-
10
20
30
40
50
60
70
2012 2013 2014 2015
Clear lens revenue
Clear lens portfolio
▪ Diverse full modality portfolio (daily to
yearly), different materials (hema /sihy
/hypergel), spherical and toric
Drivers of growth
▪ Introducing innovative
premium products while
continuing to grow user
base of long modality
lenses
▪ Professional training to ECPs
on toric and multifocal
$
$
$
$
$
$
$
M
M
M
M
M
M
M
CAGR:
11%
76
▪ Segment market with multiple offerings
and pack sizes
Lens care portfolio
21
24
28
35
-
5
10
15
20
25
30
35
40
2012 2013 2014 2015
Lens care revenue Drivers of growth
▪ Cross-sell with lens to maximize B+L strong
brand equity
$
$
$
$
$
$
$
M
M
M
M
M
M
M
$ M
CAGR:
17%
77
Cosmetic lens portfolio
12
19
23
28
-
5
10
15
20
25
30
2012 2013 2014 2015
Cosmetic lens revenue
▪ Positioning cosmetic lens as beauty
necessity, and B+L as trend setter
Drivers of growth
▪ Variety of patterns and colors, along with
full modality offeringsCAGR:
32%$
$
$
$
$
M
M
M
M
M
$ M
78
▪ Best-in-class team and talent pipeline for future growth
▪ Stable, passionate sales force committed to growing with
customers and consistently delivering results, which exceed
expectations
▪ Robust local portfolio to meet the diverse consumer needs
▪ Insights into customer needs, values, and behavior drive the
development of successful local marketing campaigns
▪ Content-based digital social media model is proven to be
effective and cost efficient
Valeant’s decentralized model has enabled
China business to grow faster than competition
We have a distinctive commercial model
79
Our pipeline in China is set up to fuel further growth
2015 2016 2017-2019
XUV-005 (Lubricant)
XUV-011 (Multifocal)
XUV-002 (Color)
XUV-014 (Multifocal)
XUV-004 (Single vision
spherical)
XUV-008 (Lubricant)
XUV-007 (Multifocal)
XUV-001 (Cosmetic)
 Biotrue ONEday
 PureVision2 Toric

Bescon half yearly
cosmetic lens

Bescon half yearly
clear lens
2017-2019 NPD Pipeline
80
Joseph Gordon: General Manager, Consumer Health
Care
Background
▪ 28 years in OTC Health Care
▪ Valeant / B+L (5 years)
▪ Wyeth (19 years)
– VP, Sales
– VP, Marketing, Advil
– GM, Nutritionals Business Unit
▪ GSK (5 years)
Education
▪ B.A. Economics, Rutgers University
81
Valeant Consumer Healthcare drivers of growth
▪ Strong and diverse portfolio of products
▪ Exceptional retailer relationships
▪ Consumer marketing expertise and effectiveness
▪ Drive recommendations through detailing of:
dermatologists, ophthalmologists, and optometrists
▪ Physicians’ intimate involvement in our product
development process
82
-2.0
-1.6
-0.4
1.0
1.41.5
2.8
4.5
5.3
5.7
6.6
7.67.77.9
9.8
Valeant is one of the fastest growing US consumer
healthcare companies
Source: IRI Market Advantage
Fastest growing US consumer healthcare companies (3-year CAGR)1, %
1 CAGR calculation based on retail sales; Total US 3 year CAGR for latest 52 weeks ending 11-29-2015. Based on biggest manufacturers in Healthcare. Excludes
private Label.
2 Alcon growth figures have been disaggregated from Novartis
2
83
Valeant has a strong portfolio of consumer products
Skin
Care
Eye
Care
Eye
Vitamins
84
Important relationships with key leading retailers
Strong account
management
Effective customer
marketing
Private label
Eye Care
category captain
85
Comprehensive marketing approach
Print Digital / social media
ProfessionalTelevision
Integrated
and diverse
consumer
marketing
86
Consumer Marketing: PreserVision
▪ 88% share of the
AREDS vitamin market
▪ First to market with
AREDS 2 formula
▪ AREDS clinically
proven
▪ Estimated 7M+
diagnosed non-users
(growth opportunity)
Net sales
Source: IRI data, NEI incidence and prevalence data
15
$100M
$80M
14
$72M
$113M
2012 2016E
$140M
2013
+8% +15% +17% +20%
AREDS 2
Launch
Q4 TV
Campaign
Launch
Consumer
Print
TV
Campaign
(continued)
Retail
consumption
growth
87
PreserVision
88
Biotrue is the fastest growing multipurpose contact
solution brand
Biotrue net sales
2013
$63M
$41M
2015
$46M
$76M
2016 E2012 2014
$88M
Source: IRI data
Biotrue Challenge
re-launched
CAGR (2012 – 2015)
▪ Biotrue: 23%
▪ Category: 1%
89
Biotrue fast facts
New users who took
the Biotrue
Challenge
Doctors’ primary
recommendation
1 Million
1/3
#1 Contact lens solution
at Walmart
Biotrue contact lens solution works like
your own eyes – 20 hours of moisture
90
Biotrue solution
91
Focusing on the professional
▪ Over 600 sales
reps selling to
dermatologists,
optometrists, and
ophthalmologists
▪ Reps have
reached 10,000
dermatologists,
distributing 15
million samples
▪ CeraVe #1
dermatologist
recommended
moisturizing brand
Source: Valeant sales force productivity, Symphony Health Survey of Dermatologists
92
CeraVe has been the fastest growing skincare brand
for four straight years
2016 E
$88M
2015
$114M
2014
$135M
12
$50M
2013
$69M
CeraVe core products
CeraVe new products
Net Sales Competitive Trends
(2013-2015 CAGR)
24%
8%
3%
▪ Professional support and involvement has driven commercial success
▪ Growth sustained in both core and new products
Category 1%
Source: IRI data
93
CeraVe has generated a digital buzz on Facebook,
boosting viral impressions by 600%
“The CeraVe Moisturizing
Lotion and Hydrating
Cleanser are just the best
products out there”
- Kathy M.
“I love your Foaming Facial
Cleanser but have recently
fallen in love with your Baby
Wash & Shampoo to clean my
face during the Winter!”
- Diana D.
“My allergist insisted I use
CeraVe…I had no idea they
had so many products!”
- Christie C.
“My dermatologist
recommended CeraVe Skincare
to me yesterday…I’m really
looking forward to trying it out!”
- Emily M.
“Seriously, CeraVe is the best
product ever. Totally obsessed
and refuse to use anything else. I
use the lotion, the wash, all of it.
Great stuff.”
- Melissa M.
“Just bought the am/pm
lotion today and I love it,
my face is so soft and
smooth…”
- April M.
94
Creating long-term growth
Recent 2016 2017 2018
Healing
ointment1
Skin
Care
Eye
Care
Eye
Vita-
mins

CeraVe
Baby
 CeraVe Sun
 CeraVe anti-
aging
 CeraVe
cleansing bar
 Peroxiclear
 SootheXP
 AREDS 2
Body wash
Anti-itch
AREDS 2
multivitamin
Targeted
therapies
Project
‘lightbulb’
Dry Eye
extension
Core
upgrades /
claims
Product
upgrade
Project
‘moisture’
AREDS 2
advanced
Note: Position of star in box does not reflect anticipated launch timing within a given year
1 All pipeline skin care products planned as part of the CeraVe family
Product
upgrade
Select product pipeline and launches
95
Valeant consumer healthcare company is poised to
continue its strong growth trajectory
~$540M
2013 2015
~$625M
2014
~$590M
Valeant US consumer healthcare revenues
High single-
digit growth
expected in
2016
96
Fernando Zarate
General Manager, Valeant Mexico, Andean region,
Central America and Caribbean (CAC)
Background
Education
▪ 24 years in Pharma industry
▪ Valeant-Mexico; General Manager (8 years)
▪ Teva (3+ years)
– OTC-Consumer Business Director
▪ Schering Plough (3+ years)
– Pharma Division Director
▪ SmithKline Beecham (7+ years)
– Consumer business Commercial Director (Venezuela-
Andean)
– Commercial Director (Mexico)
▪ M.B.A., IPADE Business School Administration
▪ B.A., Iberoamericana University (Mexico City)
97
Mexico, Central America, Andean Revenue (Constant US$)
Strong growth across all businesses
$17M
$20M
Generics
(Branded
Generics)1
$228M
Innovative (Rx)
201522014
$199M
$14M
$56M
Device
OTC
$23M
$109M
$64M
$124M
2 2015 data actual through Oct., on track to outperform forecast for Nov. and Dec.
18%
16%
14%
15%
Growth’14-’15
1 ~90% of generics in Mexico & Andean region sold as Branded Generics
15% growth
overall
98
Branded generics success in region depends on four
defining features
Well-known local
brands with
strong reputation
for quality
▪ Trusted company names: Atlantis,
Tecnofarma, Grossman
Local
manufacturing
skill and agility
▪ Two local manufacturing facilities
with internal capability to produce
injectables, oral solids, topical, liquids
▪ ~800 manufacturing employees
producing 30M units/year (30% YOY
growth)
Proven
commercial
model with direct
distribution
▪ ~600 sales employees drive
distinctive level of geographic
coverage (92%)
▪ ~45% of sales through direct
distribution channels
First-to-market
advantage
driven by local
R&D
▪ Mexico R&D team: 32 professionals
▪ 9 mo. for Valeant vs. 2-3 years for
competitors to launch new BGx
99
Mexico, Andean region, Central America and
Caribbean branded generics pipeline
We have plans to release many new branded generics in the
next few years to supplement strong growth in existing offerings
20172015
Spagnosan
(osteoporosis)
Ciscotan
(glaucoma)
Sotoldor
(glaucoma)
XUG-002 (glaucoma)
2016
XUG-012 (vaginal infections)
XUG-011 (anti-inflammatory)
XUG-001 (joint pain, RA)
XUG-003 (antifungal)
XUG-004 (oral inflammatory
disorders)
XUG-010 (ocular lubricant) XUG-013 (vaginal infections)



Select product pipeline and launches
100
Dr. Tage Ramakrishna
Chief Medical Officer, Head of R&D and Quality
Background
Education
▪ Valeant Pharmaceuticals (4 years)
– Chief Medical officer, Head of R&D and Quality
▪ Progenics Pharmaceuticals (4 years)
– VP Clinical Research
▪ Nycomed (formerly Altana) (5 years)
– Corporate VP International Drug Safety
▪ Insmed, Inc.
– Medical Director
▪ Degge Group
– Pharmacovigilance Consultant
▪ M.D., Karol Marcinkowski University of Medicine
▪ Medical College of Virginia
▪ B.A. in Biology, Rutgers University
101
R&D team
102
Valeant R&D at a glance
200+active
US programs
+
+
6
NDAs approved
in last three
years
43R&D
facilities
13
510K and PMA
approvals in
last three years
100MD, PHD, PharmD, JD
and DMD degrees
1,000R&D and quality
employees
103
R&D: Key messages
Our robust pipeline
positions us well for future
growth
We are excited about our
numerous upcoming
launches
We have a strong track
record of launching products
We are the most productive
R&D organization in the
industry
We have a distinctive R&D model with high quality people
104
Our R&D activities look similar to
other Pharma companies…
▪ Study design leveraging TA expertise
▪ Input from KOLs and customers throughout the
development process
▪ Collaboration between R&D and commercial
▪ Outsourcing rather than fixed infrastructure
▪ Internal expertise in regulatory,
pharmacovigilance, quality, and medical
affairs
105
Our execution of R&D makes our model distinctive
Eliminate
non-value added
bureaucracy
Partner with
third parties
to leverage
capabilities
Empower
individuals and
regions to make
their own
decisions
Terminate
non-promising assets
early, based on
data
Take actions
when needed,
rather than
waiting for
committees
Embrace
incremental
as well as
transformative
innovation
Outside experts
participate in key
decision meetings
(e.g., portfolio
reviews)
106
Our productivity is higher than peers
Source: Evaluate Pharma, FDA, Capital IQ, Annual reports, Press search
0.1
0.2
0.2
0.2
0.2
0.2
0.2
0.3
0.3
0.3
0.3
0.5
1.2
2.1
Top 15 average
3.02
1 Refers to New Molecular Entity and Biologic License Application
2 Does not include Contact lenses and surgical devices. Does not include B+L and Salix approved products (Fulyzaq, Bepreve and Besivance) that
were not developed under the Valeant model; all other companies include acquired brands, which overstates their productivity
“
”
Innovation has nothing to
do with how many R&D
dollars you have. When
Apple came up with the
Mac, IBM was spending at
least 100 times more on
R&D. It's not about money.
It's about the people you
have, how you're led, and
how much you get it
- Steve Jobs
R&D Productivity for 15 PharmaCos with most approvals - 2009-’14
# of NMEs/BLAs1 per $B R&D spend
107
We believe we are significantly more successful at
developing products than the industry
Source: Pharmaprojects 2014, Management Estimates
1 Average of all competitors from 2010-2014
2 2011-2015
Valeant’s success rate in dermatology2
20%18%
55%
100%
56%
69%
Ph. II Ph. IIIPh. I
Valeant2
Industry1
Success rates in dermatology
108
Global product launches
Source: Management estimates
32
131218+32
Product launches1, 2014-’15
1 Includes global line products launched in Ex-US markets
76
109
How our R&D pipeline was built
We continue to invest
in TAs with attractive
assets
We have acquired
new platforms and
capabilities in
attractive TAs
In Dermatology, we
have built capabilities
from discovery to
commercialization
Our selection and
portfolio de-risking
give us an advantage
Post-acquisition, we
have supplemented
the pipeline where
required and de-risked
where possible
We are building similar
capabilities in
Ophthalmology and GI
Internal Inherited
In-licensed /
purchased
Brodalumab
110
We have dramatically expanded our significant US
R&D programs
1 US programs only; Includes generics; excludes 90+ programs related to post marketing commitments and other small programs
2 Prior to acquisitions in TA (e.g., B+L in 2013 and Salix in 2015)
3 Includes aesthetics, women’s health, and generics
Dec. 20151Dec. 2010
Surgical 32N/A2
17Consumer 26
Dermatology 9 15
Contact lenses 9N/A2
Ophthalmology 1 7
GI 6N/A2
Others3 5 17
Total 32 112
111
We have good depth of early and late
assets across TAs
1 Prior to Phase III for Pharma, 2018+ expected launch for others 2 Includes Phase III and FDA submitted products
3 Includes aesthetics, women’s health, and generics
8
4
12
6
4
5
7
22
6
20
3
2
12
1Opthalmology 7
Contact lenses 9
GI 6
Others3 17
Surgical
Dermatology 15
26Consumer
32
40
early
72
late
112
total
Early1 Late2
Significant active US programs as of Dec. 2015
112
US prescription and generic drugs pipeline
Ophthalmology GenericsDermatology
GI In-house developmentWomen’s health
Early stage
(Pre Ph. III)
Late stage
(Ph. III - submission)
Latanoprostene Bunod:
OAG
IDP-118: PsoriasisSAL-020: HAE IDP-120: Acne
IDP-121: AcneSAL-021: RA
IDP-125: Actinic
keratosis
Relistor Oral: Opioid
induced constipation
IDP-124: Atopic
dermatitis
IDP-131: PsoriasisSAL-022: Diabetes
IDP-126: Acne IDP-122: Psoriasis
SAL-024: Crohn’s
SAL-023: Cirrhosis
BLG023: Anti-infective
IDP-127: Anti-fungal IDP-123: Acne
Brinzolamide Gx: OAG
BLO-020: Inflammation
IDP-128: Actinic
keratosis
VAL-BRO-03: Psoriatic
arthritisSPT-201: HSDD
BLG020: Disclosing
agent
IDP-129: Acne Brodalumab: Psoriasis
BLG021: Anti-infective
IDP-130: Acne
BLO-021: Cystoid
Macular edema
BLG022: Anesthetic
EGP-437: Anterior uveitis
BLO-022: Post-operative
inflammation
113
US OTC pipeline
CER-008: Lotion
CER-007: Lotion
CER-006: Wash
CER-009: Lotion
CER-005: Wash
CER-004: Ointment
CER-003: Oil
CER-002: Cream
CER-001: Oil
PUR-004: Bar
PUR-003: Wash
PUR-002: Wash
PUR-006: Cream
PUR-005: Cream
PUR-001: Wash
STS-001: Spray
CAL-001: Spray
ACF-002: Device
ACF-001: Lotion
BLO-026: Dry eye
OBG-006: Kit
BLO-024: Nutritional
BLO-023: Nutritional
BLO-025: Nutritional
OBG-005: Cleanser
OBG-004: Reformulation
OBG-003: Sunscreen
OBG-002: Skin lightener
OBG-001: Cleanser
BLO-029: Disinfectant
BLO-030: Disinfectant
BLO-028: Lubricant
BLO-027: Lubricant
Early stage Late stage
Aesthetics
Dermatology
Lens Care
Ophthalmology In-house development
Nutritionals
BLO-031: Eye whitener
114
US Devices pipeline Aesthetics Contact lenses
Surgical In-house development
Late stageEarly stage
BLS-021: Retina
BLS-023: Retina
BLS-022: Retina
BLS-024: Retina
BLS-026: Retina
BLS-027: Retina
BLS-028: Retina
BLS-029: Retina
BLS-030: Retina
BLS-031: Retina
BLS-025: Retina
BLS-032: OEM
SOF-010: Skin resurfacing
SOT-010: Fine Lines & wrinkles
SOT-011: Fine Lines & wrinkles
BLS-002: Cataract
BLS-003: Cataract
BLS-004: Cataract
BLS-005: Retina
BLS-006: Cataract
BLS-007: Cataract
BLS-001: Cataract
SOM-010 Vascular Lesions
BLC-008: Astigmatism
BLC-007: MF
BLC-009: Astigmatism
BLS-015:Cataract
BLS-016: Cataract
BLS-017: Therapeutics
BLS-018: Retina
BLS-019: Retina
BLS-020: Retina
BLS-014: Refractive
BLC-001: SVS
BLC-003: SVS/MF/fA
BLC-002: SVS
BLC-004: Toric
BLC-006: SVS
BLS-012: Retina
BLS-008: Cataract
BLS-009: Retina
BLS-010: Cataract
BLS-011: Cataract
BLC-005: SVS/MF
BLS-013: Retina
115
Ex-US pipeline Dermatology In-house developmentOphthalmology
NutritionalsGenerics Women’s health Contact lenses
1 Excludes EU Generics (listed on the next page)
Aesthetics
Lens Care
Surgical
GI
Early stage1 Late stage1
XUN-004: Nutritional
XUN-003: Magnesium caps XUO-017: Lubricant XUV-001: Cosmetic
XUN-002: Vitamins XUO-016: Lubricant
XUV-006: Lubricant
XUN-001: Nutitional XUO-015: Dry eye XUD-008: Second degree burns
XUN-005: Nutritional
XUO-018: Lubricant XUV-002: Cosmetic
XUW-002: Osteoarthritis
XUV-003: Aphakia
XUG-002: OAGXUO-002: Glaucoma XUO-009: Glaucoma XUD-002: Sunscreen
XUG-003: Anti-fungalXUO-003: Dry eye XUO-010: Conjunctivitis XUD-003: Lotion
XUG-004: Oral Inflamatory
Disorders
XUO-004: Glaucoma XUO-011: Inflammation XUD-004: Device
XUG-009: Hypertension
XUO-005: Lubricant XUO-012: Corneal lesions XUD-005: Cosmetic
XUG-001: RAXUO-001: Inflammation XUO-008: Dry eye XUD-001: cleanser
XUO-006: Decongestant XUO-013: Conjunctivitis XUD-006: Onychomycosis
XUO-014: Dry eye XUD-007: CosmeticsXUO-007: Decongestant
XUV-004: SVS
XUW-001: HSDD
XUV-005: LubricantXUA-001: Hair removal
LAV-006: Lubricant
LAV-001: Aphakia
XUI-001: IBS-D
XUD-009: Emollient
XUN-006: Nutitional
XUN-007: Nutritional
XUV-007: MF
XUV-011: MF
XUV-008: Lubricant
XUV-009: SVS
XUV-010: Astigmatism
XUV-012: SVS
XUV-013: Astigmatism
XUV-014: Presbyopia
XUV-015: MF
XUG-006: Diabetes
XUG-007: Hypertension
XUG-008: Hypertension
XUG-005: Cholestrol
XUG-013: Vaginal Infections
XUG-010: Ocular lubricant
XUG-011: Anti-Inflammatory
XUG-012: Vaginal Infections
116
EU generics pipeline In-house development
Early stage Late stage
EUG-012: Glaucoma EUG-044: 0 EUG-070: Copd EUG-095: GlaucomaEUG-026: Local hemostasis
EUG-013: Glaucoma
EUG-045: Benign prostatic
hyperplasia
EUG-071: Asthma EUG-096: Glaucoma
EUG-027: Prevention of
deep vein thrombosis
EUG-046: Benign prostatic
hyperplasia
EUG-079: Allergy EUG-097: Glaucoma
EUG-028: Chronic nevous
insufficiency
EUG-047: Rheumatoid
arthritis
EUG-080: Allergy EUG-098: Eye infections
EUG-029: Chronic nevous
insufficiency
EUG-048: Osteoporosis EUG-081: Pain EUG-099: GlaucomaEUG-030: Hypertension
EUG-051: Bacterial
infections
EUG-082: Eye vitamins EUG-100: GlaucomaEUG-031: Hypertension
EUG-052: Cell lung cancer EUG-083: Allergy EUG-101: Glaucoma
EUG-032: Hypertension,
heart failure
EUG-057: Mlaignant
melanoma
EUG-033: Hypertension,
heart failure
EUG-001: Hypertension EUG-034: Hypertension
EUG-059: Lung and
pancreatic cancer
EUG-086: Adrenocortical
insufficiency
EUG-014: Antispasmotic
EUG-002: Acne vulgaris EUG-035: Angina pectoris EUG-060: Pain EUG-087: Dry eyeEUG-015: Hypertension
EUG-003: Atopic dermatitis
EUG-036:
Hypercholesterolemia
EUG-061: Pain EUG-088: Eye inflamationEUG-016: Dermtitis
EUG-004: Acne vulgaris
EUG-037:
Hypercholesterolemia
EUG-064: Schisofrenia EUG-089: Eye inflamationEUG-017: Antiseptic
EUG-005: Acne vulgaris
EUG-038: Prevention of
blod clots
EUG-065: Schisofrenia EUG-090: Dry eyeEUG-018: Cough and cold
EUG-006: Hypertension
EUG-039: Whitenning
cream
EUG-066: Pain EUG-091: Eye infectionsEUG-019: Eye inflamation
EUG-009: Dermatitis EUG-040: Cosmetics EUG-067: Pain EUG-092: Eye inflammation
EUG-020: Chemotherapy
induced nauzea
EUG-010: Severe acne EUG-041: Atopic dermatitis EUG-068: Cough and cold EUG-093: AllergyEUG-021: Type II diabetes
EUG-011: Hyperuricemia
EUG-042: Bacterial skin
lesions
EUG-069: Asthma, copd EUG-094: Dry eye
EUG-022: Haemorrhoids -
early stage
EUG-084: Glaucoma
EUG-058: Myeloma
EUG-085: Allergic
conjuctivitis
Generics
117
Select pipeline opportunities
Brodalumab
Relistor Oral
Latanoprostene
Bunod (LBN)
Drug1 Indication
Expected
launch
US
Prevalence
Opioid induced
constipation (OIC)
with chronic non-
cancer pain
2017/18IDP118 Moderate to
severe plaque
psoriasis
Reduction of
Intraocular
pressure in patients
with Open Angle
Glaucoma (OAG)
and Ocular
hypertension
2016
2016
2016
~9.5M
~3.7M
~3.0M
Source: Decision Resources, BioMed Tracker
Moderate to
severe plaque
psoriasis
~9.5M
1 Product candidates, not yet approved by the FDA
118
Relistor Oral could be a new option for patients
suffering from opioid induced constipation (OIC) with
chronic non-cancer pain
Source: Digestive Disease Week, 2012 (R. Rauck, J.Peppin, R.Israel, J. Carpentino, J.Cohn, S.Huang, E.Bortley,
C.Paterson, W.Forbes)
1 Peripherally acting, selective μ-opioid receptor antagonist with restricted CNS penetration
2 Product candidate, not yet approved by the FDA
3 Rescue-free bowel movement - defined as a bowel movement that occurred without laxative use (i.e., no laxative use within 24 hrs prior to the
bowel movement); tested for within 4 hours of dosing during daily dosing period
4 Severe adverse events
27.424.6
18.1
MNTX 450 mgMNTX 300 mgPlacebo
28.9
9.4
Placebo 12 mg QD
MNTX 3201 Oral formulation Primary Efficacy Endpoint (% of
respondents1)
MNTX 3356 SC Formulation Co-Primary Efficacy Endpoint
▪ Subcutaneous injection
currently approved for OIC
in patients with advanced
illness and chronic non-
cancer pain
▪ Oral methylnaltrexone2 300
mg and 450 mg
significantly increased the
percentage of patients
with a RFBM3 within 4 hours
▪ Incidence of SAEs4 was 3%
in the all tested groups
versus 4% in the placebo
group
119
Latanoprostene Bunod (LBN) ophthalmic solution
(0.024%) combines Latanoprost and Nitric Oxide in a
single molecule to lower Intraocular pressure (IOP)
LBN will be the first novel OAG
monotherapy approved in 20
years:
▪ Nitric oxide plays a key role in
numerous functions throughout
the body including many well
documented functions in the
healthy eye1
▪ Glaucoma patients have lower
levels of ocular nitric oxide than
those observed in normal eyes2,3
▪ LBN4 lowers IOP by increasing
outflow through both the
uveoscleral and trabecular
meshwork pathways
▪ PDUFA date – July 21st 2016
1 Culotta E, et al. Science. 1992;258:1862-5
2 Nathanson JA, et al. Invest Ophthalmol Vis Sci. 1995;36:1774-84
3 Galassi F, et al. Br J Ophthalmol. 2004;88:757-760
4 Product candidate, not yet approved by the FDA
Source: Mayo Clinic
Open Angle Glaucoma (OAG)
120
Clinical Studies Support Viability of LBN (1/2)
Summary of Phase II results
Reduction in mean diurnal IOP on day 7, 14 and 28
9.0
8.9
8.3
7.8
7.7
7.3
Day 14 Day 28Day 7
Latanoprostene bunod 0.024%
Latanoprost 0.005%
P = 0.033 P = 0.015 P = 0.005
In a Phase II dose-ranging
study, LBN3 showed positive
results including
consistently better control
of IOP over 28 days as well
as a statistically significant
greater percentage of
responders vs. latanoprost
0.005%1,2
1 Defined as patients achieving an IOP ≤18 mm Hg
2 Weinreb RH, et al. Br J Ophthalmology. 2015;99:738-45
3 Product candidate, not yet approved by the FDA
121
Clinical Studies Support Viability of LBN (2/2)
Summary of results of two phase III pivotal studies
▪ In two phase III studies LBN provided a mean IOP reduction of 7.5-9.1 mm
Hg over three months of treatment (statistically superior to timolol
between 2 and 12 weeks)1
▪ LBN3 was safe and well tolerated with no significant adverse events.1,2
Rates for hyperemia were comparable to latanoprost2
1 Data on file
2 Weinreb RH, et al. Br J Ophthalmology. 2015;99:738-45
3 Product candidate, not yet approved by the FDA
122
R. Todd Plott, MD
Dermatologist
Background
▪ 16 years in the pharmaceutical drug development
including at Medicis Pharmaceuticals
▪ Led the development of Solodyn, Vanos, Ziana,
Loprox Shampoo and Ammunol while at Medicis
▪ Over the past 5 years, in solo dermatology practice
in Ft Worth, TX
▪ Unpaid (expenses only paid) Valeant R&D
consultant; holds no Valeant stock
Education
▪ University of Texas Medical Branch Galveston, M.D.
▪ University of Arkansas Heath Sciences - Intern and
Dermatology Residency
▪ National Cancer Institute - Fellowship
123
• Patients have a medical need for the unique
dermatology drug products that manufacturers provide
• Access to these drugs can be a problem
• Many manufacturers offer drug assistance programs for
patients
• Drug assistance programs have been very helpful to
patients
• Patients do better when they get the medications that
they need
My observations
124
IDP118 – Topical Treatment of Psoriasis
▪A combination topical drug product1 containing and
retinoid and a steroid
▪Phase II clinical results suggest the combination is
superior to the individual components
▪Expected completion Phase III Studies - Q4 2016
1 Product candidate; not yet approved by the FDA
125
Brodalumab is an anti–interleukin-17 receptor-A
mAB that could address moderate-to-severe psoriasis
▪ Brodalumab 210 mg was superior to
placebo and to ustekinumab1 in
treatment of moderate-to-severe
psoriasis
▪ Symptoms of psoriasis reduced ~2x
faster than the median response
time with ustekinumab (4.1 weeks vs.
8.1 weeks)2
▪ Results for Brodalumab3 210 mg
were confirmed in two phase III
studies
Source: New England Journal of Medicine (M. Lebwohl, B. Strober, A. Menter)
1 At week 12, PASI 75 response rates were significantly higher with brodalumab at a dose of 210 mg and at a dose of 140 mg than with placebo
2 Tested median time to a PASI 75 response for patient arm given 210 mg of brodalumab every 2 week
3 Product candidate, not yet approved by the FDA
PASI 75
response
PASI 100
response
0
50
100
69%
09
6%
1205
85%
10
Week
69%
Response rate (%)
110706 080402 031
0
50
100
03 1004 080705
0.3%
19%
02 0906 111
Response rate (%)
Week
12
37%
27%
126
Looking forward
▪ We have a history of successes
across key therapeutic areas
▪ We have intelligently invested in
R&D to build a deep and exciting
pipeline
▪ I am passionate about our R&D
model and strategy, and confident
about the future
127
Drivers of Valeant’s success
Our decentralized model and talented people, which give
us a competitive edge (speed of decision making and in-
depth customer knowledge)
Our collection of great healthcare brands around the
world
Our innovative strategies (often disruptive), which have
challenged industry convention
Our relentless focus on providing easy and affordable
access for physicians and patients
Our exceptionally productive approach to R&D
128
EMT
J. Michael Pearson
Chairman of the Board
and Chief Executive
Officer
Robert Chai-Onn
Executive Vice
President, General
Counsel and Chief
Legal Officer
Robert Rosiello
Executive Vice
President and Chief
Financial Officer
Dr. Pavel Mirovsky
President and General
Manager, Europe
Dr. Ari Kellen
Executive Vice
President/Company
Group Chairman
Anne Whitaker
Executive Vice
President/Company
Group Chairman
Deb Jorn
Executive Vice
President Dermatology
and GI
Tom Appio
Sr. Vice President - Asia
Pacific, Managing
Director, China
129
Senior Management Team Panel
J. Michael Pearson
Chairman of the Board
and Chief Executive Officer
Robert Rosiello
Executive Vice President
and Chief Financial Officer
Dr. Pavel Mirovsky
President and General
Manager, Europe
Dr. Ari Kellen
Executive Vice
President/Company Group
Chairman
Anne Whitaker
Executive Vice
President/Company Group
Chairman
Deb Jorn
Executive Vice President
Dermatology and GI
Tanya Carro
Senior Vice President,
Finance and
Corporate Controller
Dr. Tage Ramakrishna
Chief Medical Officer,
Head of R&D and Quality
Tracy Valorie
Senior Vice President and
General Manager,
Women’s Health and
Bausch + Lomb
Pharmaceutical Division
130
Financial guidance appendix
131
To supplement the financial measures prepared in accordance with U.S. generally accepted accounting
principles (GAAP), the company uses the following non-GAAP financial measures: Adjusted EPS, non-GAAP
revenue, non-GAAP cost of goods, non-GAAP selling, general and administrative expenses, Adjusted Cash flow
from Operations. Reconciliations of these non-GAAP financial measures to their most directly comparable
GAAP financial measure can be found in our earnings release and Form 8-K on Tables 2 through 2b, Table 3,
Table 4 and Table 5.2, respectively. A copy of the earnings release, including financial schedules, is posted on
the “Investors” section of the Valeant.com website. In addition, Adjusted EBITDA is a non-GAAP financial
measure that will be provided in our earnings releases and Form 8-K going forward.
The Company does not provide guidance with respect to GAAP financial measures other than revenues or
provide reconciliations to GAAP of its forward-looking [non-GAAP financial measures] due to the inherent
difficulty in quantifying certain amounts that would be required to be included in the GAAP measure of
earnings per share due to their unknown effect, timing and potential significance. Examples of these items
include impairments of assets, gains and losses from the extinguishment of debt, legal settlements, purchases of
in-process research and development assets, and gains and losses from asset sales. Accordingly, the GAAP
calculation of projected net income (loss) is not available for Valeant without unreasonable efforts.
By disclosing the non-GAAP financial measures referenced above, management intends to provide investors
with a meaningful, consistent comparison of the company’s baseline operating results and trends for the
periods presented by excluding items that are considered by the company not to be reflective of the
company’s ongoing results. Management uses all of the above named non-GAAP financial measures internally
for strategic decision making, forecasting future results and evaluating current performance. [For example: to
set internal budgets, evaluating company performance, setting incentive compensation targets and planning
and forecasting of future periods] Non-GAAP financial measures are not prepared in accordance with GAAP.
Therefore, the information is not necessarily comparable to other companies and should be considered as a
supplement to, not a substitute for, or superior to, the corresponding measures calculated in accordance with
GAAP.
Definition of terms
132
Adjusted EPS* (non-GAAP) multiplied by Shares Outstanding
Add:
Taxes
Interest
Share Based Compensation
Depreciation
Adjusted EBITDA*
Note: Adjusted EBITDA as defined in our Credit Agreement excludes certain charges and
includes certain pro forma adjustments for acquisitions and divestitures. Details of the
Adjusted EBITDA calculations per our Credit Agreement can be found in our Credit
Agreement, which is filed as an exhibit to our 10-K and can be found in the investor relations
section of the Valeant website.
* See Page* Non-GAAP
Adjusted EBITDA calculation

Más contenido relacionado

La actualidad más candente

Valeant allergan investor presentation final
Valeant allergan investor presentation finalValeant allergan investor presentation final
Valeant allergan investor presentation finalValeant_Pharmaceuticals
 
Bausch + Lomb Acquisition Conference Call
Bausch + Lomb Acquisition Conference CallBausch + Lomb Acquisition Conference Call
Bausch + Lomb Acquisition Conference CallValeant_Pharmaceuticals
 
Valeant Pharmaceuticals' Investor Day 2012 Download
Valeant Pharmaceuticals' Investor Day 2012 DownloadValeant Pharmaceuticals' Investor Day 2012 Download
Valeant Pharmaceuticals' Investor Day 2012 DownloadValeant_Pharmaceuticals
 
Cardinal Health Q1 FY 2017 Earnings Presentation
Cardinal Health Q1 FY 2017 Earnings PresentationCardinal Health Q1 FY 2017 Earnings Presentation
Cardinal Health Q1 FY 2017 Earnings PresentationCardinal_Health
 
Cardinal Health Q3 FY 2016 Earnings Presentation
Cardinal Health Q3 FY 2016 Earnings PresentationCardinal Health Q3 FY 2016 Earnings Presentation
Cardinal Health Q3 FY 2016 Earnings PresentationCardinal_Health
 
Shire - The Path to US$10 Billion in Product Sales by 2020
Shire - The Path to US$10 Billion in Product Sales by 2020Shire - The Path to US$10 Billion in Product Sales by 2020
Shire - The Path to US$10 Billion in Product Sales by 2020Company Spotlight
 
Shire - Jefferies 2014 Global Healthcare Conference
Shire - Jefferies 2014 Global Healthcare ConferenceShire - Jefferies 2014 Global Healthcare Conference
Shire - Jefferies 2014 Global Healthcare ConferenceCompany Spotlight
 
Q1 fy16 earnings deck final
Q1 fy16 earnings deck finalQ1 fy16 earnings deck final
Q1 fy16 earnings deck finalCardinal_Health
 
Dsp investor deck september 2017 final
Dsp investor deck september 2017 finalDsp investor deck september 2017 final
Dsp investor deck september 2017 finalDiplomatIR
 
J.P. Morgan 34th Annual Healthcare Conference Presentation
J.P. Morgan 34th Annual Healthcare Conference PresentationJ.P. Morgan 34th Annual Healthcare Conference Presentation
J.P. Morgan 34th Annual Healthcare Conference PresentationCardinal_Health
 
35th Annual J.P. Morgan Healthcare Conference Presentation
35th Annual J.P. Morgan Healthcare Conference Presentation35th Annual J.P. Morgan Healthcare Conference Presentation
35th Annual J.P. Morgan Healthcare Conference PresentationCardinal_Health
 
Cardinal Health 2015 Investor & Analyst Day
Cardinal Health 2015 Investor & Analyst DayCardinal Health 2015 Investor & Analyst Day
Cardinal Health 2015 Investor & Analyst DayCardinal_Health
 
Cah q4 fy17 presentation
Cah q4 fy17 presentationCah q4 fy17 presentation
Cah q4 fy17 presentationCardinal_Health
 
Cardinal Health Dublin Day Presentation
Cardinal Health Dublin Day PresentationCardinal Health Dublin Day Presentation
Cardinal Health Dublin Day PresentationCardinal_Health
 
Cardinal Health 2016 Annual Shareholder Meeting Presentation
Cardinal Health 2016 Annual Shareholder Meeting PresentationCardinal Health 2016 Annual Shareholder Meeting Presentation
Cardinal Health 2016 Annual Shareholder Meeting PresentationCardinal_Health
 
Cah investorand analystday dec10.2013
Cah investorand analystday dec10.2013Cah investorand analystday dec10.2013
Cah investorand analystday dec10.2013Cardinal_Health
 
J.P. Morgan 33rd Annual Healthcare Conference
J.P. Morgan 33rd Annual Healthcare ConferenceJ.P. Morgan 33rd Annual Healthcare Conference
J.P. Morgan 33rd Annual Healthcare ConferenceCardinal_Health
 
McKesson and Cardinal Health Comparative Analysis
McKesson and Cardinal Health Comparative AnalysisMcKesson and Cardinal Health Comparative Analysis
McKesson and Cardinal Health Comparative AnalysisJorge Santillan
 

La actualidad más candente (20)

Valeant allergan investor presentation final
Valeant allergan investor presentation finalValeant allergan investor presentation final
Valeant allergan investor presentation final
 
Bausch + Lomb Acquisition Conference Call
Bausch + Lomb Acquisition Conference CallBausch + Lomb Acquisition Conference Call
Bausch + Lomb Acquisition Conference Call
 
Valeant Pharmaceuticals' Investor Day 2012 Download
Valeant Pharmaceuticals' Investor Day 2012 DownloadValeant Pharmaceuticals' Investor Day 2012 Download
Valeant Pharmaceuticals' Investor Day 2012 Download
 
2 q14 presentation draft final
2 q14 presentation draft final2 q14 presentation draft final
2 q14 presentation draft final
 
Cardinal Health Q1 FY 2017 Earnings Presentation
Cardinal Health Q1 FY 2017 Earnings PresentationCardinal Health Q1 FY 2017 Earnings Presentation
Cardinal Health Q1 FY 2017 Earnings Presentation
 
Cardinal Health Q3 FY 2016 Earnings Presentation
Cardinal Health Q3 FY 2016 Earnings PresentationCardinal Health Q3 FY 2016 Earnings Presentation
Cardinal Health Q3 FY 2016 Earnings Presentation
 
Shire - The Path to US$10 Billion in Product Sales by 2020
Shire - The Path to US$10 Billion in Product Sales by 2020Shire - The Path to US$10 Billion in Product Sales by 2020
Shire - The Path to US$10 Billion in Product Sales by 2020
 
Shire - Jefferies 2014 Global Healthcare Conference
Shire - Jefferies 2014 Global Healthcare ConferenceShire - Jefferies 2014 Global Healthcare Conference
Shire - Jefferies 2014 Global Healthcare Conference
 
Q1 fy16 earnings deck final
Q1 fy16 earnings deck finalQ1 fy16 earnings deck final
Q1 fy16 earnings deck final
 
Dsp investor deck september 2017 final
Dsp investor deck september 2017 finalDsp investor deck september 2017 final
Dsp investor deck september 2017 final
 
20150218 investor document 4 q final2
20150218 investor document 4 q final220150218 investor document 4 q final2
20150218 investor document 4 q final2
 
J.P. Morgan 34th Annual Healthcare Conference Presentation
J.P. Morgan 34th Annual Healthcare Conference PresentationJ.P. Morgan 34th Annual Healthcare Conference Presentation
J.P. Morgan 34th Annual Healthcare Conference Presentation
 
35th Annual J.P. Morgan Healthcare Conference Presentation
35th Annual J.P. Morgan Healthcare Conference Presentation35th Annual J.P. Morgan Healthcare Conference Presentation
35th Annual J.P. Morgan Healthcare Conference Presentation
 
Cardinal Health 2015 Investor & Analyst Day
Cardinal Health 2015 Investor & Analyst DayCardinal Health 2015 Investor & Analyst Day
Cardinal Health 2015 Investor & Analyst Day
 
Cah q4 fy17 presentation
Cah q4 fy17 presentationCah q4 fy17 presentation
Cah q4 fy17 presentation
 
Cardinal Health Dublin Day Presentation
Cardinal Health Dublin Day PresentationCardinal Health Dublin Day Presentation
Cardinal Health Dublin Day Presentation
 
Cardinal Health 2016 Annual Shareholder Meeting Presentation
Cardinal Health 2016 Annual Shareholder Meeting PresentationCardinal Health 2016 Annual Shareholder Meeting Presentation
Cardinal Health 2016 Annual Shareholder Meeting Presentation
 
Cah investorand analystday dec10.2013
Cah investorand analystday dec10.2013Cah investorand analystday dec10.2013
Cah investorand analystday dec10.2013
 
J.P. Morgan 33rd Annual Healthcare Conference
J.P. Morgan 33rd Annual Healthcare ConferenceJ.P. Morgan 33rd Annual Healthcare Conference
J.P. Morgan 33rd Annual Healthcare Conference
 
McKesson and Cardinal Health Comparative Analysis
McKesson and Cardinal Health Comparative AnalysisMcKesson and Cardinal Health Comparative Analysis
McKesson and Cardinal Health Comparative Analysis
 

Similar a Valeant Investor Day 2015 Presentation

Diplomat Pharmacy Inc - November 2016 Investors Presentation
Diplomat Pharmacy Inc - November 2016 Investors PresentationDiplomat Pharmacy Inc - November 2016 Investors Presentation
Diplomat Pharmacy Inc - November 2016 Investors PresentationDiplomatIR
 
Dsp investor deck jp morgan january 2017 final2
Dsp investor deck jp morgan january 2017 final2Dsp investor deck jp morgan january 2017 final2
Dsp investor deck jp morgan january 2017 final2DiplomatIR
 
Q22015 earnings deck final august 11 revised
Q22015 earnings deck final august 11 revisedQ22015 earnings deck final august 11 revised
Q22015 earnings deck final august 11 revisedValeant_Pharmaceuticals
 
Dsp investor deck june 2016 william blair
Dsp investor deck june 2016 william blairDsp investor deck june 2016 william blair
Dsp investor deck june 2016 william blairDiplomatIR
 
Dplo investor deck april 2015
Dplo investor deck april 2015Dplo investor deck april 2015
Dplo investor deck april 2015DiplomatIR
 
Dsp investor deck may 2017 051017
Dsp investor deck may 2017 051017Dsp investor deck may 2017 051017
Dsp investor deck may 2017 051017DiplomatIR
 
Dsp investor deck march 2016 raymond james
Dsp investor deck march 2016 raymond jamesDsp investor deck march 2016 raymond james
Dsp investor deck march 2016 raymond jamesDiplomatIR
 
Dsp Investor deck jan 2016 JP Morgan final
Dsp Investor deck jan 2016 JP Morgan finalDsp Investor deck jan 2016 JP Morgan final
Dsp Investor deck jan 2016 JP Morgan finalDiplomatIR
 
KeyBanc Industrial, Automotive and Transportation Conference Presentation
KeyBanc Industrial, Automotive and Transportation Conference Presentation KeyBanc Industrial, Automotive and Transportation Conference Presentation
KeyBanc Industrial, Automotive and Transportation Conference Presentation Hillenbrand_IR
 
Quintiles william blair-35th-annual-growth-stock-conference
Quintiles william blair-35th-annual-growth-stock-conferenceQuintiles william blair-35th-annual-growth-stock-conference
Quintiles william blair-35th-annual-growth-stock-conferencepatyi_2000
 
September Investor Presentation
September Investor PresentationSeptember Investor Presentation
September Investor PresentationDiplomatIR
 
Mondelez 2016 CAGNY Presentation
Mondelez 2016 CAGNY PresentationMondelez 2016 CAGNY Presentation
Mondelez 2016 CAGNY PresentationNeil Kimberley
 
William blair-35th-annual-growth-stock-conference
William blair-35th-annual-growth-stock-conferenceWilliam blair-35th-annual-growth-stock-conference
William blair-35th-annual-growth-stock-conferenceQuintiles2014
 
investor-presentation-jefferies-2016.pptx
investor-presentation-jefferies-2016.pptxinvestor-presentation-jefferies-2016.pptx
investor-presentation-jefferies-2016.pptxssuser26e38f
 
GNC Presentation on Growth from 2011
GNC Presentation on Growth from 2011GNC Presentation on Growth from 2011
GNC Presentation on Growth from 2011Neil Kimberley
 
Merck FY 2016
Merck FY 2016 Merck FY 2016
Merck FY 2016 Merck
 
Dsp investor deck september 2017 final
Dsp investor deck september 2017 finalDsp investor deck september 2017 final
Dsp investor deck september 2017 finalDiplomatIR
 

Similar a Valeant Investor Day 2015 Presentation (20)

Jpm 2015 final2
Jpm 2015 final2Jpm 2015 final2
Jpm 2015 final2
 
Diplomat Pharmacy Inc - November 2016 Investors Presentation
Diplomat Pharmacy Inc - November 2016 Investors PresentationDiplomat Pharmacy Inc - November 2016 Investors Presentation
Diplomat Pharmacy Inc - November 2016 Investors Presentation
 
Dsp investor deck jp morgan january 2017 final2
Dsp investor deck jp morgan january 2017 final2Dsp investor deck jp morgan january 2017 final2
Dsp investor deck jp morgan january 2017 final2
 
Q22015 earnings deck final august 11 revised
Q22015 earnings deck final august 11 revisedQ22015 earnings deck final august 11 revised
Q22015 earnings deck final august 11 revised
 
Dsp investor deck june 2016 william blair
Dsp investor deck june 2016 william blairDsp investor deck june 2016 william blair
Dsp investor deck june 2016 william blair
 
Dplo investor deck april 2015
Dplo investor deck april 2015Dplo investor deck april 2015
Dplo investor deck april 2015
 
Dsp investor deck may 2017 051017
Dsp investor deck may 2017 051017Dsp investor deck may 2017 051017
Dsp investor deck may 2017 051017
 
Dsp investor deck march 2016 raymond james
Dsp investor deck march 2016 raymond jamesDsp investor deck march 2016 raymond james
Dsp investor deck march 2016 raymond james
 
Guidance presentation jan 2015 final2
Guidance presentation jan 2015 final2Guidance presentation jan 2015 final2
Guidance presentation jan 2015 final2
 
Dsp Investor deck jan 2016 JP Morgan final
Dsp Investor deck jan 2016 JP Morgan finalDsp Investor deck jan 2016 JP Morgan final
Dsp Investor deck jan 2016 JP Morgan final
 
KeyBanc Industrial, Automotive and Transportation Conference Presentation
KeyBanc Industrial, Automotive and Transportation Conference Presentation KeyBanc Industrial, Automotive and Transportation Conference Presentation
KeyBanc Industrial, Automotive and Transportation Conference Presentation
 
3 q13 presentation final final2
3 q13 presentation final final23 q13 presentation final final2
3 q13 presentation final final2
 
Quintiles william blair-35th-annual-growth-stock-conference
Quintiles william blair-35th-annual-growth-stock-conferenceQuintiles william blair-35th-annual-growth-stock-conference
Quintiles william blair-35th-annual-growth-stock-conference
 
September Investor Presentation
September Investor PresentationSeptember Investor Presentation
September Investor Presentation
 
Mondelez 2016 CAGNY Presentation
Mondelez 2016 CAGNY PresentationMondelez 2016 CAGNY Presentation
Mondelez 2016 CAGNY Presentation
 
William blair-35th-annual-growth-stock-conference
William blair-35th-annual-growth-stock-conferenceWilliam blair-35th-annual-growth-stock-conference
William blair-35th-annual-growth-stock-conference
 
investor-presentation-jefferies-2016.pptx
investor-presentation-jefferies-2016.pptxinvestor-presentation-jefferies-2016.pptx
investor-presentation-jefferies-2016.pptx
 
GNC Presentation on Growth from 2011
GNC Presentation on Growth from 2011GNC Presentation on Growth from 2011
GNC Presentation on Growth from 2011
 
Merck FY 2016
Merck FY 2016 Merck FY 2016
Merck FY 2016
 
Dsp investor deck september 2017 final
Dsp investor deck september 2017 finalDsp investor deck september 2017 final
Dsp investor deck september 2017 final
 

Más de Valeant_Pharmaceuticals (14)

20150218 investor document 4 q final2
20150218 investor document 4 q final220150218 investor document 4 q final2
20150218 investor document 4 q final2
 
20150218 investor document 4 q final2
20150218 investor document 4 q final220150218 investor document 4 q final2
20150218 investor document 4 q final2
 
Jpm 2014
Jpm 2014Jpm 2014
Jpm 2014
 
3 q14 presentation
3 q14 presentation3 q14 presentation
3 q14 presentation
 
Valeant Pharmaceuticals Correct Recent Misrepresentations
Valeant Pharmaceuticals Correct Recent MisrepresentationsValeant Pharmaceuticals Correct Recent Misrepresentations
Valeant Pharmaceuticals Correct Recent Misrepresentations
 
6.02.14 final improved offer deck final3
6.02.14 final improved offer deck final36.02.14 final improved offer deck final3
6.02.14 final improved offer deck final3
 
1 q14 presentation final2
1 q14 presentation final21 q14 presentation final2
1 q14 presentation final2
 
4 q13 presentation final
4 q13 presentation final4 q13 presentation final
4 q13 presentation final
 
Guidance presentation jan 2014 final
Guidance presentation jan 2014 finalGuidance presentation jan 2014 final
Guidance presentation jan 2014 final
 
Q2 2013 Financial Results
Q2 2013 Financial ResultsQ2 2013 Financial Results
Q2 2013 Financial Results
 
Q1 2013 Financial Results Conference Call
Q1 2013 Financial Results Conference CallQ1 2013 Financial Results Conference Call
Q1 2013 Financial Results Conference Call
 
1 q13 presentation final v001_g5vnb4
1 q13 presentation final v001_g5vnb41 q13 presentation final v001_g5vnb4
1 q13 presentation final v001_g5vnb4
 
4Q 2012 Presentation
4Q 2012 Presentation4Q 2012 Presentation
4Q 2012 Presentation
 
Jpm presentation 2013 final final
Jpm presentation 2013 final finalJpm presentation 2013 final final
Jpm presentation 2013 final final
 

Último

Short-, Mid-, and Long-term gxxoals.pptx
Short-, Mid-, and Long-term gxxoals.pptxShort-, Mid-, and Long-term gxxoals.pptx
Short-, Mid-, and Long-term gxxoals.pptxHenryBriggs2
 
Methanex Investor Presentation (April 2024)
Methanex Investor Presentation (April 2024)Methanex Investor Presentation (April 2024)
Methanex Investor Presentation (April 2024)Methanex Corporation
 
VIP Kolkata Call Girl Entally 👉 8250192130 Available With Room
VIP Kolkata Call Girl Entally 👉 8250192130  Available With RoomVIP Kolkata Call Girl Entally 👉 8250192130  Available With Room
VIP Kolkata Call Girl Entally 👉 8250192130 Available With Roomdivyansh0kumar0
 
The exim bank in power point presentation
The exim bank in  power point presentationThe exim bank in  power point presentation
The exim bank in power point presentationsharmahemant3612
 
Malad Escorts, (Pooja 09892124323), Malad Call Girls Service
Malad Escorts, (Pooja 09892124323), Malad Call Girls ServiceMalad Escorts, (Pooja 09892124323), Malad Call Girls Service
Malad Escorts, (Pooja 09892124323), Malad Call Girls ServicePooja Nehwal
 
Call Girl Kolkata Sia 🤌 8250192130 🚀 Vip Call Girls Kolkata
Call Girl Kolkata Sia 🤌  8250192130 🚀 Vip Call Girls KolkataCall Girl Kolkata Sia 🤌  8250192130 🚀 Vip Call Girls Kolkata
Call Girl Kolkata Sia 🤌 8250192130 🚀 Vip Call Girls Kolkataanamikaraghav4
 
Cyberagent_For New Investors_EN_240424.pdf
Cyberagent_For New Investors_EN_240424.pdfCyberagent_For New Investors_EN_240424.pdf
Cyberagent_For New Investors_EN_240424.pdfCyberAgent, Inc.
 
Collective Mining | Corporate Presentation - April 2024
Collective Mining | Corporate Presentation - April 2024Collective Mining | Corporate Presentation - April 2024
Collective Mining | Corporate Presentation - April 2024CollectiveMining1
 
Teck Investor Presentation, April 24, 2024
Teck Investor Presentation, April 24, 2024Teck Investor Presentation, April 24, 2024
Teck Investor Presentation, April 24, 2024TeckResourcesLtd
 
High Profile Call Girls Kolkata Gayatri 🤌 8250192130 🚀 Vip Call Girls Kolkata
High Profile Call Girls Kolkata Gayatri 🤌  8250192130 🚀 Vip Call Girls KolkataHigh Profile Call Girls Kolkata Gayatri 🤌  8250192130 🚀 Vip Call Girls Kolkata
High Profile Call Girls Kolkata Gayatri 🤌 8250192130 🚀 Vip Call Girls Kolkataanamikaraghav4
 
Q3 FY24 Earnings Conference Call Presentation
Q3 FY24 Earnings Conference Call PresentationQ3 FY24 Earnings Conference Call Presentation
Q3 FY24 Earnings Conference Call PresentationSysco_Investors
 
Russian Call Girls Kolkata Indira 🤌 8250192130 🚀 Vip Call Girls Kolkata
Russian Call Girls Kolkata Indira 🤌  8250192130 🚀 Vip Call Girls KolkataRussian Call Girls Kolkata Indira 🤌  8250192130 🚀 Vip Call Girls Kolkata
Russian Call Girls Kolkata Indira 🤌 8250192130 🚀 Vip Call Girls Kolkataanamikaraghav4
 
Call Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In Amritsar
Call Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In AmritsarCall Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In Amritsar
Call Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In Amritsaronly4webmaster01
 
slideshare Call girls Noida Escorts 9999965857 henakhan
slideshare Call girls Noida Escorts 9999965857 henakhanslideshare Call girls Noida Escorts 9999965857 henakhan
slideshare Call girls Noida Escorts 9999965857 henakhanhanshkumar9870
 
《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...
《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...
《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...wyqazy
 

Último (20)

Vip Call Girls Vasant Kunj ➡️ Delhi ➡️ 9999965857 No Advance 24HRS Live
Vip Call Girls Vasant Kunj ➡️ Delhi ➡️ 9999965857 No Advance 24HRS LiveVip Call Girls Vasant Kunj ➡️ Delhi ➡️ 9999965857 No Advance 24HRS Live
Vip Call Girls Vasant Kunj ➡️ Delhi ➡️ 9999965857 No Advance 24HRS Live
 
Short-, Mid-, and Long-term gxxoals.pptx
Short-, Mid-, and Long-term gxxoals.pptxShort-, Mid-, and Long-term gxxoals.pptx
Short-, Mid-, and Long-term gxxoals.pptx
 
Methanex Investor Presentation (April 2024)
Methanex Investor Presentation (April 2024)Methanex Investor Presentation (April 2024)
Methanex Investor Presentation (April 2024)
 
VIP Kolkata Call Girl Entally 👉 8250192130 Available With Room
VIP Kolkata Call Girl Entally 👉 8250192130  Available With RoomVIP Kolkata Call Girl Entally 👉 8250192130  Available With Room
VIP Kolkata Call Girl Entally 👉 8250192130 Available With Room
 
The exim bank in power point presentation
The exim bank in  power point presentationThe exim bank in  power point presentation
The exim bank in power point presentation
 
Malad Escorts, (Pooja 09892124323), Malad Call Girls Service
Malad Escorts, (Pooja 09892124323), Malad Call Girls ServiceMalad Escorts, (Pooja 09892124323), Malad Call Girls Service
Malad Escorts, (Pooja 09892124323), Malad Call Girls Service
 
Call Girl Kolkata Sia 🤌 8250192130 🚀 Vip Call Girls Kolkata
Call Girl Kolkata Sia 🤌  8250192130 🚀 Vip Call Girls KolkataCall Girl Kolkata Sia 🤌  8250192130 🚀 Vip Call Girls Kolkata
Call Girl Kolkata Sia 🤌 8250192130 🚀 Vip Call Girls Kolkata
 
Cyberagent_For New Investors_EN_240424.pdf
Cyberagent_For New Investors_EN_240424.pdfCyberagent_For New Investors_EN_240424.pdf
Cyberagent_For New Investors_EN_240424.pdf
 
Call Girls 🫤 Mukherjee Nagar ➡️ 9999965857 ➡️ Delhi 🫦 Russian Escorts FULL ...
Call Girls 🫤 Mukherjee Nagar ➡️ 9999965857  ➡️ Delhi 🫦  Russian Escorts FULL ...Call Girls 🫤 Mukherjee Nagar ➡️ 9999965857  ➡️ Delhi 🫦  Russian Escorts FULL ...
Call Girls 🫤 Mukherjee Nagar ➡️ 9999965857 ➡️ Delhi 🫦 Russian Escorts FULL ...
 
Collective Mining | Corporate Presentation - April 2024
Collective Mining | Corporate Presentation - April 2024Collective Mining | Corporate Presentation - April 2024
Collective Mining | Corporate Presentation - April 2024
 
Teck Investor Presentation, April 24, 2024
Teck Investor Presentation, April 24, 2024Teck Investor Presentation, April 24, 2024
Teck Investor Presentation, April 24, 2024
 
High Profile Call Girls Kolkata Gayatri 🤌 8250192130 🚀 Vip Call Girls Kolkata
High Profile Call Girls Kolkata Gayatri 🤌  8250192130 🚀 Vip Call Girls KolkataHigh Profile Call Girls Kolkata Gayatri 🤌  8250192130 🚀 Vip Call Girls Kolkata
High Profile Call Girls Kolkata Gayatri 🤌 8250192130 🚀 Vip Call Girls Kolkata
 
Call Girls In Vasant Kunj 📱 9999965857 🤩 Delhi 🫦 HOT AND SEXY VVIP 🍎 SERVICE
Call Girls In Vasant Kunj 📱  9999965857  🤩 Delhi 🫦 HOT AND SEXY VVIP 🍎 SERVICECall Girls In Vasant Kunj 📱  9999965857  🤩 Delhi 🫦 HOT AND SEXY VVIP 🍎 SERVICE
Call Girls In Vasant Kunj 📱 9999965857 🤩 Delhi 🫦 HOT AND SEXY VVIP 🍎 SERVICE
 
Q3 FY24 Earnings Conference Call Presentation
Q3 FY24 Earnings Conference Call PresentationQ3 FY24 Earnings Conference Call Presentation
Q3 FY24 Earnings Conference Call Presentation
 
Russian Call Girls Kolkata Indira 🤌 8250192130 🚀 Vip Call Girls Kolkata
Russian Call Girls Kolkata Indira 🤌  8250192130 🚀 Vip Call Girls KolkataRussian Call Girls Kolkata Indira 🤌  8250192130 🚀 Vip Call Girls Kolkata
Russian Call Girls Kolkata Indira 🤌 8250192130 🚀 Vip Call Girls Kolkata
 
Call Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In Amritsar
Call Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In AmritsarCall Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In Amritsar
Call Girls In Amritsar 💯Call Us 🔝 76967 34778🔝 💃 Independent Escort In Amritsar
 
slideshare Call girls Noida Escorts 9999965857 henakhan
slideshare Call girls Noida Escorts 9999965857 henakhanslideshare Call girls Noida Escorts 9999965857 henakhan
slideshare Call girls Noida Escorts 9999965857 henakhan
 
Russian Call Girls Rohini Sector 22 💓 Delhi 9999965857 @Sabina Modi VVIP MODE...
Russian Call Girls Rohini Sector 22 💓 Delhi 9999965857 @Sabina Modi VVIP MODE...Russian Call Girls Rohini Sector 22 💓 Delhi 9999965857 @Sabina Modi VVIP MODE...
Russian Call Girls Rohini Sector 22 💓 Delhi 9999965857 @Sabina Modi VVIP MODE...
 
《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...
《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...
《加州大学圣克鲁兹分校学位证书复制》Q微信741003700美国学历疑难问题指南|挂科被加州大学圣克鲁兹分校劝退没有毕业证怎么办?《UCSC毕业证购买|加...
 
Rohini Sector 15 Call Girls Delhi 9999965857 @Sabina Saikh No Advance
Rohini Sector 15 Call Girls Delhi 9999965857 @Sabina Saikh No AdvanceRohini Sector 15 Call Girls Delhi 9999965857 @Sabina Saikh No Advance
Rohini Sector 15 Call Girls Delhi 9999965857 @Sabina Saikh No Advance
 

Valeant Investor Day 2015 Presentation

  • 1. Valeant: An Enduring Engine for Growth December 16, 2015
  • 2. 1 Forward-looking Statements Forward-looking Statements Certain statements made in this presentation may constitute forward-looking statements, including, but not limited to, statements regarding guidance with respect to expected revenues, non-GAAP cash earnings per share, adjusted cash flows from operations and organic product sales growth, future disclosures, launches and approvals of products, business development activities, and the 2016 strategic initiatives of Valeant Pharmaceuticals International, Inc. (the “Company”). Forward-looking statements may be identified by the use of the words “anticipates,” “expects,” “intends,” “plans,” “could,” “should,” “would,” “may,” “will,” “believes,” “estimates,” “seeks,” “potential,” or “continue” and variations or similar expressions. These statements are based upon the current expectations and beliefs of management, and depend on assumptions, data or methods that may be incorrect or imprecise and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. These risks and uncertainties include, but are not limited to, risks and uncertainties discussed in the Company's most recent annual or quarterly report filed with the Securities and Exchange Commission ("SEC") and other risks and uncertainties detailed from time to time in the Company's filings with the SEC and the Canadian Securities Administrators ("CSA"), which factors are incorporated herein by reference. Readers are cautioned not to place undue reliance on any of these forward-looking statements. The Company undertakes no obligation to update any of these forward-looking statements to reflect events or circumstances after the date of this presentation or to reflect actual outcomes. Note 1: The guidance in this presentation is only effective as of the date given, December 15, 2015, and will not be updated or affirmed unless and until the Company publicly announces updated or affirmed guidance.
  • 3. 2 J. Michael Pearson Chairman and CEO <portrait>
  • 4. 3 Drivers of Valeant’s success Our decentralized model and talented people, which give us a competitive edge (speed of decision making and in- depth customer knowledge) Our collection of great healthcare brands around the world Our innovative strategies (often disruptive), which have challenged industry convention Our relentless focus on providing easy and affordable access for physicians and patients Our exceptionally productive approach to R&D
  • 5. 4 A collection of great brands in a breadth of therapeutic areas Valeant 2016 forecast revenues 19% 21% Gastrointestinal (GI) 17% Emerging markets (including Ophthalmology, Dermatology, and GI sales) 22% Ophthalmology and Eye Care (B+L) Dermatology and Skin Care22% Oncology, Dentistry, Women’s Health, Neuro and Other Total: $12.5 – 12.7 B
  • 6. 5 Dermatology ▪ Great brands in attractive segments ▪ Importance of trust-based physician relationships ▪ Concentrated, specialist prescriber base ▪ Attractive from a payor standpoint – High component of cash pay – Reasonably priced products ▪ Lower-cost, lower risk R&D 4-year mkt CAGR: ~5%
  • 7. 6 ▪ Strong underlying global growth drivers (e.g., demographics) ▪ Attractive specialty Rx and OTC segments ▪ Importance of trust-based physician relationships ▪ Concentrated, specialist prescriber base ▪ Significant unmet medical needs ▪ Opportunity for lower-risk innovation ▪ Low exposure to reimbursement pressure; significant cash pay ▪ Durable products 4-year mkt CAGR: ~6% Ophthalmology (B+L)
  • 8. 7 Gastrointestinal ▪ Concentrated, specialist prescriber population ▪ Importance of trust-based physician relationships ▪ Concentrated, specialist prescriber base ▪ Less of a priority for many larger pharma companies ▪ Favorable reimbursement ▪ Opportunity for low-risk, incremental innovation
  • 9. 8 Emerging markets ▪ 1,000+ brands with sales in emerging markets ▪ High growth markets (e.g., Mexico, China, Middle East / North Africa) ▪ Rich pipeline of upcoming launches ▪ Decentralized operating model ▪ Products not dependent on reimbursement ▪ Local R&D capabilities 4-year mkt CAGR: ~7%
  • 10. 9 Valeant Access Program with Walgreens – Physician/Pharmacist/Patient-led experience ▪ Direct distribution to patients through Walgreens ▪ All products in Walgreens on consignment; Walgreens never takes title ▪ Walgreens paid a distribution and pharmacy fulfillment fee ▪ Valeant sets prices to the patient ▪ Ensures affordable, immediate access to all Valeant brands in program that physicians prescribe (for eligible patients) Branded Access Program Branded Generic Access Program
  • 11. 10 Our innovative strategies – the early years ▪ Dramatically reduced OPEX (e.g., to focus predominantly on customer-facing areas) ▪ Shifted from high- risk/high-spend R&D (e.g. neurology, virology) to lower cost “singles and doubles” ▪ Built unrivaled M&A capabilities (e.g., requiring returns in excess of cost of capital) ▪ Began building undervalued BGx and OTC businesses (e.g., in emerging markets) ▪ Initiated new R&D capability and operating model (e.g., Dow) ▪ Executed merger of equals with Biovail (strong strategic fit, improved tax rate) 2008 2009 2010 ▪ ~$600M in revenue ▪ 8% operating margin and 1% growth ▪ Imminent Effudex generics ▪ Bloated cost base and infrastructure ▪ High risk, high spend R&D ▪ Demotivated organization Then
  • 12. 11 Our innovative strategies – recent years ▪ Gained critical mass in ophthalmology with acquisition of B+L ▪ New R&D model beginning to pay dividends ▪ Created attractive access program in dermatology initially through partnership with Philidor ▪ Built a leading US market position in dermatology, with a series of focused acquisitions (e.g., Medicis, Obagi, Dermik/Ortho) ▪ Secured entry into attractive GI space with acquisition of Salix ▪ Created even better, branded access program with Walgreens ▪ Launched with Walgreens the first branded generics program in the US 2011 /12 2013 /14 2015 ▪ $12.5-12.7B in revenue ▪ Double-digit organic growth ▪ Great brands around the world ▪ Attractive geographies and TA platforms ▪ Energized and committed talent base Now
  • 13. 12 Our R&D model Rx R&D spend as a % of branded Rx sales 8% ▪ 6 NDAs approved in last 3 years ▪ 200+ active US programs ▪ Dermatology Phase II and Phase III success rates 3-5x better than industry averages ▪ Highest 5 year output1 on R&D spend in the industry 1 Number of NMEs/BLAs approved 2009-'14 for each $1 billion spent; peer set is 15 companies with the highest number of NME/BLA approvals
  • 14. 13 Our decentralized model ▪ Empowers local leaders to make decisions that are right for their business ▪ Allows us to move with speed and agility ▪ Aligns with our customers’ needs ▪ Ensures strong centralization and controls in key functions/ activities, e.g., – Finance – Compliance – Audit – Pharmacovigilance
  • 15. 14 How you can measure our progress in 2016 ▪ Retained all key management talent and added new key hires ▪ Dermatology returned to growth ▪ Maximized Xifaxan – created our first $1B brand ▪ Got approval and successfully launched – Brodalumab – Latanoprostene Bunod – Relistor Oral ▪ Delivered $100-150M in addyi sales in 2016 ▪ Brought leverage to ~4.0x by end of 2016
  • 16. 15 Who you will hear from – Our business leaders Yang Yang BU Director, Vision Care China & Japan Fernando Zarate GM, Mexico, Andean region, Central America and Caribbean Joe Gordon SVP and GM, Consumer Health Care Deb Jorn EVP, Dermatology and GI Dr. Tage Ramakrishna Chief Medical Officer, Head of R&D and Quality Robert Rosiello EVP, CFO Tracy Valorie SVP and GM, Women’s Health and Bausch + Lomb Pharmaceutical Division Mark McKenna VP and GM, Bausch + Lomb
  • 17. 16 Robert Rosiello Executive VP, CFO <portrait> Financial guidance
  • 18. 17 * Non-GAAP (see Appendix) Previous Q4 2015 Guidance Revised Q4 2015 Guidance ~$3.25 - $3.45B ~$2.7 - $2.8B ~$4.00 - $4.20 per share ~$2.55 - $2.65 per share >$1.0B >$600M Revenue Adjusted EPS* Adj. Cash Flow from Operations* Revised Q4 2015 and full-year 2015 guidance
  • 19. 18 Midpoint of previous guidance Midpoint of revised guidance ~$3,350M ~$4.10 Revenue Adjusted EPS* Philidor separation Estimated one-time revenue impact from Walgreens transition Pricing and volume-related changes (e.g., non- promoted products) ~($250M) ~($150M) ~($200M) ~($0.65) ~($0.40) ~($0.45) ~$2,750M ~$2.60 * Non-GAAP (see Appendix) Bridge from previous Q4 2015 guidance
  • 20. 19 Estimated Q4 Revenue Impact: (~$250M)  Announced Philidor separation October 30  Provided free scripts from October 31 to November 8  Dispensed refills without seeking reimbursement from payors from November 9 to present  Average cash pay price declined from $67 to $23  Lost ~20% of scripts from business disruption in Q4, virtually all Philidor covered scripts Philidor separation
  • 21. 20  Transition to consignment model at Walgreens for current inventory on hand  Under this arrangement, Valeant will hold title to products sold under this program until dispensed to a patient  Valeant will credit Walgreens for any inventory on hand in its stores or distribution centers as part of transition  Estimated reduction in traditional channel inventories for the products included in Walgreens program One-time revenue impact from Walgreens transition
  • 22. 21 2016 Guidance ~$12.5B – 12.7B ~$13.25 – 13.75 per share ~$6.9 – 7.1B Revenue Adj. EPS* Adj. EBITDA* * Non-GAAP (see Appendix) 2016 guidance
  • 23. 22 Previous 2016 Adj. EBITDA* Outlook 2016 Adj. EBITDA* Guidance (Mid-point) >$7.50B Dermatology Patient Access Program ramp-up ~($225M) ~$7.0B Changes in pricing assumptions ~($125M) Employee retention bonuses ~($75M) Incremental legal fees ~($75M) * Non-GAAP (see Appendix) Bridge from previous 2016 EBITDA outlook
  • 24. 23 Revised 2015 Guidance 2016 Guidance 2016 Guidance % over Updated 2015 Guidance $10.4B – 10.5B ~$12.5B – 12.7B ~21% Double-Digit Double-Digit NA $10.23 – 10.33 per share ~$13.25 – 13.75 per share ~31% >$5.4B $6.9 – 7.1B ~30% Revenue Organic Growth* Adj. EPS* Adj. EBITDA* * Non-GAAP (see Appendix) 2016 guidance vs. revised 2015 guidance
  • 25. 24  Exchange rates based on current spot rates  No use of balance sheet/acquisitions  Planned impact from generics expected ~($140M) in revenues  Glumetza (Q1); Zegerid (Q3); Nitropress (Q4); Virazole (Q4)  No use of balance sheet/acquisitions  U.S. branded drugs (excluding drugs in the Walgreens program) consistent with PBM, managed care contracts  Other U.S. businesses (e.g., contact lenses, consumer) typically no more than CPI  Ex-U.S. driven by volume, pricing impact is immaterial  Negotiated price discounts for hospital-administered drugs of ~30% (e.g., Nitropress, Isuprel, Virazole, Ammunol)  COGS* ~20-21%  SG&A* ~23-24%  R&D spend ~$400-500M * Non-GAAP (see Appendix) 2016 guidance assumptions (1/2)
  • 26. 25  Restructuring charges expected <$200M  Higher charges in Q1 and Q2 due to completion of restructuring and integration programs for Salix, Sprout, Synergetics, Amoun, trending downward in Q3 and Q4  Cash tax rate expected to be ~5%  Interest expense ~$1.6B  Sequential quarters for Revenue and Adjusted EPS* are expected to be higher than the previous quarter  2H will be substantially higher than 1H due to ramp up in Walgreen’s programs  Cash Flow Items  Cap Ex - ~$350M  Depreciation - ~$200M  Stock Based Comp - ~$200M (includes impact of employee retention plan) 2016 guidance assumptions (2/2) * Non-GAAP (see Appendix)
  • 27. 26 Q1 2016 Guidance $2.8 - $3.1B $2.35 - $2.55 per share  Dermatology Patient Access Program ramp-up  Continued impact of reduction in channel inventories Revenue Adj. EPS* Q1 2016 guidance * Non-GAAP (see Appendix)
  • 28. 27  Majority of 2016 free cash flow used for debt pay down  Committed to minimum debt pay down in 2016 of >$2.25B including $562M term loan amortization and $260M maturities  Remain in clear compliance with credit agreement financial maintenance covenants  Senior secured leverage covenant: 2.5x (secured debt to pro forma adjusted EBITDA*)  Interest coverage covenant: 2.25x though March 31, 2016, then 3.0x (pro forma adjusted EBITDA* to pro forma interest coverage)  Net leverage to pro forma adjusted EBITDA* expected to be ~4x by year end  Minimal amortization and maturities until 2018  2016: $822M  2017: $631M  2018: $2,923M + $1,500M (Revolver) * Non-GAAP (see Appendix) Balance sheet update
  • 29. 28  Cash flow  “Adjusted cash flow from operations” and “Cash conversion” will no longer be reported each quarter  Only GAAP Cash Flow will be reported going forward  We will continue to report integration expenses by acquisition on quarterly basis so investors can continue to calculate adjusted cash flow, if desired  Adjusted EBITDA* will be reported on a quarterly basis  “Cash EPS” to be labeled “Adjusted EPS* (non-GAAP)”  Top 30 global brands  Volume and Price/Mix for total company and U.S. branded Rx business * Non-GAAP (see Appendix) Changes to planned quarterly disclosures
  • 30. 29 Deb Jorn: EVP, Dermatology and GI Background ▪ 30+ years in Pharma industry ▪ Bausch + Lomb; VP and CMO (3 years) ▪ Schering-Plough (5+ years) – VP for Women’s Healthcare and Fertility – VP for Allergy, Respiratory, and Urology ▪ J&J (2 years) – VP for Internal Medicine ▪ Pharmacia Corporation (2 years) – VP for Detrol / Detrusitol and Urology ▪ Merck (20 years) – Executive Director, Worldwide Human Health Marketing; Respiratory Products; senior marketing roles Education ▪ M.B.A., NYU Stern Graduate School of Business Administration ▪ B.A., Rutgers University
  • 33. 32 Key Takeaways • Valeant is the #1 Medical Dermatology Company1 in the U.S. • Internal R&D efforts resulted in approval of 4 new products in 2014 (Jublia, Onexton, RAM .08, Luzu) • Strong near-term pipeline expected to sustain organic growth • Deep, trust-based relationships with dermatologists and podiatrists • New Valeant Access Program, in partnership with Walgreens, launching in January 2016 Source: Symphony Monthly PHAST Audit MAT October 2015 1. Excluding biologics and oral antibiotics *Dermatology Rx refers to entire USC2 37000 (Dermatological, Ethical) **Sales are based on MBS Dollar Sales (MBS represents a standardized dollar metric based on manufacturer’s published catalog or list prices to wholesalers
  • 34. 33 Oct 30th 2015 – Nov 8th 2015  No submission of claims to payors after October 30th  All prescriptions filled at no cost to patient  Commercial insured and uninsured only – no government plans 3 phase transition plan Phase I: Initial Transition  Rapidly developed new access program  Entered into agreement with Walgreens  Prepared for execution with excellence Nov 9th 2015 until new program in place (before Jan 30th 2016 Philidor closing)  $35 cash pay option for all new and refill prescriptions sent to Philidor  Refills already in Philidor prior to Nov 9th filled for $0 if previous refill was that copay or $35  Commercial insured and uninsured only – no government plans Phase II: Full Transition Phase III: Relaunch
  • 35. 34 Key recent actions Customer outreach  20 cities covered in 6 weeks by senior management and sales & marketing team  Reaffirmed commitment to Dermatology / Podiatry specialty Retention  Retained all sales & marketing leaders  Retained all but two sales representatives out of field force of over 350  Maintained historic vacancy rate of 5% (lower than industry norms) New Access Program  Gathered input regarding key elements of new access program  Established new relationship with leading consumer retailer (Walgreens), streamlining prescription process for patients and physicians
  • 36. 35 We have retained 81% of dermatology prescriptions - 20,000 40,000 60,000 80,000 100,000 120,000 140,000 Pre Post Covered Uncovered Cash Retail 1 October average pre Philidor 2 November average, excluding Thanksgiving week post Philidor 1 2 # of weekly TRx ▪ Retail prescriptions grew by 17% to 66,000, mitigating overall drop in total prescriptions ~116,000 ~94,000 +17% Philidor
  • 37. 36 Valeant’s new access program ▪ Ensures affordable, convenient patient access to medicines prescribed by their physician1 ▪ Some products as low as $0 ▪ Allows physicians, NPs and PAs to focus their efforts on patient care ▪ Sales force will start providing physicians with program overview as of Dec 21st ▪ Goal: fully operational January 15th 1 Commercial insured and uninsured only – no government plans 2
  • 38. 37 New access program is simpler for patients and physicians New Approach HCP sends Rx to Walgreens Patient picks up Rx at Walgreens same day Old Approach HCP sends Rx to Philidor Patient calls Philidor with insurance, credit card 2-3 days later Rx arrives at home
  • 39. 38 9/14 YTD 9/15 YTDQ3 YTD 2014 Q3 YTD 2015 Strong Organic Growth in Dermatology Valeant Dermatology Revenues 1 Brands launched 2014+: Luzu (Q2 14), Jublia (Q3 14), Ram08 (Q3 14), and Onexton (Q1 15) $1,266M $718M 0 20 40 60 80 100 120 140 160 Q2 2014 Q3 2014 Q4 2014 Q1 2015 Q2 2015 Q3 2015 New Product Revenue1 $150M/quarter 76% In-line brandLaunch brand1 Total Revenue
  • 40. 39 Exciting Late-stage Dermatology Pipeline 2017+ IDP – 121 (acne vulgaris) 2016 Brodalumab (plaque psoriasis) IDP – 122 (plaque psoriasis) IDP – 118 (plaque psoriasis) IDP – 120 (acne vulgaris) Select pipeline products
  • 42. 41 Gut GuyTM Hepatic Encephalopathy (HE) Irritable Bowl Syndrome – diarrhea (IBS-D) Xifaxan 550mg
  • 43. 42 TV PRINT DIGITAL 75 55 80 65 50 85 70 60 Oct- 15 Oct- 14 Jul- 14 Apr- 15 Jan- 15 Jul- 15 IBS-D indication Drives Xifaxan TRx Growth *Note: TRx’s are Unit-adjusted each month based on the different Pack Sizes of 42 and 60 Source: Symphony PHAST 2.0 IBS-D Indication Retail + Hospital TRx’s* DTC Launch Thousands of Xifaxan scripts (US) +27% TRx 81K Rx / month 64K Rx / month
  • 44. 43  Up to 8M in US at risk for Chronic Liver Disease1, including those with Overt HE  Only 2 products are approved for Overt HE: lactulose and Xifaxan  2014 AASLD/EASL Guidelines recommended the addition of Xifaxan to lactulose to maintain Overt HE remission, which has been shown to reduce risk of Overt HE recurrence by 58% and hospitalizations by 50%2  Today only 45% of NRx for Lactulose are written with Xifaxan, creating a large untapped opportunity for Xifaxan to help HE patients Xifaxan continues to have substantial growth potential in hepatic encephalopathy (HE) 1 Includes patients with HepB, HepC, NAFLD, NSH, and OHE; source: National Institute of Diabetes and Digestive and Kidney Disease. Digestive Diseases Statistics for the United States. Assessed September 7, 2010 2 Bass NM, Mullen KD, Sanyal A, et al. Rifaxamin treatment in hepatic encephalopathy. N Engl Med. 2010;362(12):1071-1081
  • 45. 44  Increase sales force by a further 100 representatives to support Xifaxan growth in HE  Expand the GI team in high density areas  Increase continuity of care between sales teams working in hospitals and out-patient settings Key actions to accelerate Xifaxan growth
  • 46. 45 Strong growth of in-line brands Source: Symphony PHAST 2.0 + VA Procurement, Non-Retail TRx’s are unit-adjusted each month based on the different Pack Sizes of 42 and 60 * Since Ruconest Launched in Dec 2014, Growth Rates are 5 vs. 5 months (instead of 12 vs. 12 months). Brand % TRx Growth YOY October Apriso 8% Uceris 30% Relistor 33% Ruconest* 140%
  • 47. 46  An estimated 3% of the adults in the US are receiving long- term opioid therapy  41% of those patients, or approximately 3.7 million patients, develop Opioid Induced Constipation (OIC)  The prescription market for OIC is growing rapidly now that there is an oral option  In our phase III program, Relistor oral significantly increased the percentage of patients with a rescue-free bowel movement (RFBM) within 4 hours Relistor Oral (April 19, 2016 PDUFA) Source: Spencer Dorn, et al. American Journal of GASTROENTEROLOGY 2014
  • 48. 47 Strong Late-stage GI Pipeline 2017+2015 Xifaxan IBS-D SAL-023 Chronic cirrhosis of liver 2016 Relistor Oral Opiod induced constipation SAL-024 Crohn's SAL-022 Diabetes SAL -021 Rheumatoid arthritis SAL-020 Hereditary angioedema Select pipeline products and launches 
  • 49. 48 Tracy Valorie: SVP and GM, Women’s Health and B+L Pharmaceutical Ophthalmology Background Education ▪ 20+ years in Pharma industry ▪ Bausch + Lomb – Vice President of Pharmaceutical Marketing – Former Global Head of Glaucoma ▪ Pfizer – Global Commercial Lead of Ophthalmology (Xalabrands and Macugen), mid-stage development portfolio, and long-range planning ▪ Experience in discovery, clinical development, commercial assessment, marketing and strategic planning ▪ Previous board membership The Glaucoma Foundation and ARVO Foundation for Eye Research (AFER) ▪ M.B.A., Rensselaer Polytechnic Institute ▪ B.S. Molecular Biology, University of Connecticut
  • 50. 49 addyi is a breakthrough product with great potential ▪ addyi is the first FDA approved product for Hypoactive Sexual Dysfunction Disorder (HSDD) in premenopausal women and is not the “Female Viagra” ▪ Hypoactive Sexual Dysfunction Disorder effects many premenopausal women – ~15M premenopausal women have HSDD – Only 10% diagnosed – Opportunity to educate on the disease state and expand the diagnosed population ▪ Physician and Patient Education, and managing expectations is critical to success, including: – Education on disease state – Physician and patient education on features, benefits, and risks of addyi
  • 51. 50 Challenge ahead of us: TRx’s are not being filled Source: McKesson 0 1000 2000 3000 4000 5000 6000 7000 8000 Oct-23 Oct-30 Nov-06 Nov-13 Nov-20 Nov-27 Dec-04 Dec-11 addyi TRx (# TRx cumulative) TRx filled Total TRx -82%
  • 52. 51 Physician sentiment is positive “ ” Physicians are optimistic about addyi as an FDA approved treatment option ” It is fantastic that we have an FDA- approved medication for a woman with a sexual health concern… I did not think this was possible prior to this day and age “ ” We discuss and write scripts for multiple patients in our clinic every day Physicians who have experience with addyi are enthusiastic about its potential Physicians caution that managing expectations is crucial “ Physicians need to be educated on the disease state and the product so they can appropriately counsel patients on how the product works and what they can expect Source: Symphony, RelayHealth as of Dec. 2015, physician outreach “ ”
  • 53. 52 We have a strong assessment of the issues ▪ Limited physician education / awareness of HSDD and addyi ▪ Confusion around REMS certification process (physicians and pharmacies) ▪ Sales force targeting not optimal
  • 54. 53 Go forward plan ▪ Remove barriers to REMS certification ▪ Physician and patient outreach, MSL recruiting and training ▪ Build an integrated Valeant team (Commercial, Medical, Sales, etc.) ▪ Improve field force effectiveness – Revisit targeting and call plan – Improve reach and frequency on key targets – Retrain our sales force – Enhance performance management ▪ Improve patient access (thru Walgreens Access Program as of Jan. 15th)
  • 55. 54 Market Access: Continuing to improve ▪ 50% of US lives are covered to date ▪ >1/3 of all US lives have unrestricted coverage ▪ Managed Markets team is working diligently with our payor stakeholders to improve accessUnrestricted coverage Restricted coverage 50% U.S. lives covered Seeking coverage / under negotiation 35% 15%
  • 56. 55 addyi: 2016 Expectations USD 100-150M+ net revenue
  • 57. 56 Mark McKenna: Vice President and General Manager, Bausch + Lomb Background ▪ 13+ Years of diverse experience in the eye health category in leadership roles across sales, marketing, operations and strategy ▪ Led the reinvigoration of the U.S. contact lens product portfolio, making Bausch + Lomb the fastest growing contact lens company in the U.S. ▪ Held positions of increasing responsibility in Bausch + Lomb’s sales and marketing division, most recently as Head of Sales and Operations ▪ Global Marketing experience leading new product development projects for Bausch + Lomb from ideation through commercialization ▪ Joined Bausch + Lomb in 2006 after spending several years with Johnson & Johnson Vision Care ▪ Speaker at the 5th Annual Life Science Executive Leadership forum Education ▪ MBA from Azusa Pacific University ▪ BA in Marketing from Arizona State University
  • 59. 58 The resurgence of an iconic eye care brand ▪ Valeant has transformed the underperforming Bausch + Lomb (B+L) company into a $1.2B+ diversified vision care business ▪ Products are outgrowing category averages through commercial investments in the US and a decentralized model ▪ Global roll out of contact lens pipeline, which will build on US and Asia success ▪ One of the fastest growing contact lens solution brands in the world ▪ Strong pipeline, with >20 product launches and extensions planned for next 3 years globally
  • 60. 59 B+L contact lens business turnaround under Valeant US B+L contact lens revenue and growth in millions ▪ Innovation and Organic Growth: Our investments in R&D, DTC marketing and manufacturing have allowed us to drive organic growth in vision care ▪ Distinctive Commercial Model: Our physician oriented approach has enabled us to transform Biotrue® ONEday into one of the fastest growing daily disposable brands 20% lens CAGR under Valeant ownership vs 5% lens category CAGR1 $- $50 $100 $150 $200 $250 $300 2009 2010 2011 2012 2013 2014 2015 2016 -1% -7% -2% -8% -8% +16% +26% +26% Source: Management estimates, 3rd party data 1 Category CAGR over same time period Annual growth E
  • 61. 60 B+L is growing rapidly relative to competitors Source: 3rd party data, Company filings Lens sales growth 2013-’15 6% Market Average1 5% -3% 22% 7% 1 B+L and top market competitors 2 Excludes private label sales Solutions sales growth 2013-’15 -1% -5% 0% 7% All others2 2% Market Average1
  • 62. 61 Winning Strategies for Contact Lenses • Expanded Sales Force by 50% to increase frequency and reach • Signed multi-year partnership agreements with leading optical retailers; Vision Source (#2) and NVI (#4) • Accelerated Bausch + Lomb ULTRA Multifocal & Toric launches by 12 months 20%+ Annual Growth Next 3 Years • Upgraded organization with top industry talent • Formed Professional Strategy group to enhance peer-to-peer outreach • Innovative launch strategies to maximize launch trajectory Forge Higher Performance Leadership Team Enhance Operational Effectiveness Strengthen Customer Partnerships Launch Excellence Accelerate the Pipeline
  • 63. 62 Bausch + Lomb ULTRA® is Fastest Growing Frequent Replacement Contact Lens  Sales: Forecasted to more than double from $45M in 2015 to $100M+ in 2016  Share: Unprecedented 7.9 share within 18 months of launch  Distribution: Gained +13k doorways in 2015 resulting in 22k total ECP’s1 with diagnostic fitting sets  DTC Campaign: Delivered over 1B impressions via Digital, Social, and Paid Search in 2015, and TV spots planned for first half of 20160 1 2 3 4 5 6 7 8 9 ULTRA share of dollars in FRP category 1 Eye care professionals Source: 3rd party data, Management Estimates Marketshare(%)
  • 64. 63 Bausch + Lomb ULTRA®
  • 65. 64 Bausch + Lomb ULTRA, a CLEAR standout in recent Eye Care Professional poll Cleveland Research Company, Nov 2015 34% 22% 19% 15% 7% 3%0% 10% 20% 30% 40% ULTRA Clariti Freshday MOIST for Presbyopia Acuvue OASYS One Day Air Optix Colors MyDay When ECP’s Were Asked: Which recently launched lens has gained the most traction in your practice?
  • 66. 65 Bausch + Lomb ULTRA® 2016 Launch Activities Launching Bausch + Lomb ULTRA® for Presbyopia and Astigmatism in 2016  Expand Bausch + Lomb ULTRA® reach by 35% of the market (multifocal and toric)  Halo effect on Spherical business Investing Multi-Million Dollar in DTC campaign  TV, Digital, Social Media, Search  In-office Digital Displays to create 360 campaign Targeted Professional Outreach  Largest Eye Care Professional Share of Voice within contact lens industry  High impact launch events to generate awareness and request of new products
  • 67. 66 Biotrue® ONEday is one of the fastest growing daily disposable brands through a change in go-to-market strategy US Biotrue ONEday net sales since acquisition 0 1 2 3 4 5 6 7 8 9 Q3 '13 Q4 '13 Q1 '14 Q2 '14 Q3 '14 Q4 '14 Q1 '15 Q2 '15 Q3 '15 Base trend Biotrue ONEday is on track to achieve a 60% YOY growth rate in 2015 Sales($M)
  • 68. 67 New Product Launches Planned Over the Next Years Across Lens and Lens Care 13 3 2015 2016 Q2 Q3 Q4Q1 2017 - 2020 BLC-009 (Astigmatism)  Biotrue Multifocal BLC-007 (Multifocal) BLC-008 (Astigmatism) BLO-030 (Disinfectant) ▪ BLC-003 (single vision spherical / multifocal / astigmatism) ▪ BLC-005 (single vision spherical / multifocal) ▪ BLC-001 (single vision spherical) ▪ BLC-006 (single vision spherical) ▪ BLC-002 (cosmetic single vision spherical) ▪ BLC-004 (Novel Astigmatism) ▪ BLO-027 (Lubricant) ▪ BLO-028 (Lubricant) ▪ BLO-029 (Disinfectant) Select product pipeline and launches
  • 69. 68 Yang Yang: Business Unit Director, Vision Care China & Japan Background ▪ 15+ years China and overseas consumer marketing & sales experience. Born and raised in Beijing, China ▪ Bausch + Lomb / Valeant (China & Japan) - Business Unit Director – Vision Care - Marketing Director – Vision Care ▪ L'Oréal (China) - Director of e-commerce – L'Oréal Paris, Maybelline, & Garnier - Marketing Director – Garnier ▪ Johnson & Johnson Consumer Products - Marketing Manager – Listerine, Carefree, & o.b. (China) - Brand Manager – Reach & Visine (USA) ▪ Citigroup CitiCards – New Product Development (USA) ▪ Procter & Gamble (China) - Category Management Manager - Key Account Manager & Unit Manager Education ▪ MBA, University of Michigan, Ross School of Business ▪ BA English Language & Literature, Peking University
  • 71. 70 Vision care is growing strongly in Asia Japan Korea Thailand Hong Kong Singapore India China Taiwan Malaysia Vision care sales $491 million (2015) +6% annual growth
  • 72. 71 Valeant China business overview 15%Rx Vision Care45% 25% Surgical 15% OTC eye drop ▪ 1st contact lens company to enter China; the brand name has been used as synonym for contact lens ▪ B+L is the #1 recognized brand in China and preferred by consumers ▪ B+L is also the #1 vision care brand in China, with fastest growth Valeant China business by franchise 2015 Total China sales: $ 277M
  • 73. 72 2014 China lens market by modality revenue & % growth: ~$284M, +3% 2014 China vision care market revenue & % growth: ~$438M, +2% 44% 21% 35% Lens care 24% 22% 54% Clear lens DailyHalf yearly / Yearly MonthlyCosmetic lens +4% +1% +1% +2% -3% +15% China Market – All companies NOTE: USD at constant dollars Source: CLI, credit report and trade intelligence China is a half yearly / yearly lens market; cosmetic lens is 1/3 of total lens market
  • 74. 73 B+L is the #1 and the fastest growing vision care brand in China Source: CLI, credit report, and trade intelligence 2013-’14 growth rate % Revenue 2014 $M $125 $105 $57 $49 $8 $438 Market Share 2014 % 28% 24% 13% 11% 2% 100% 16 9 8 -6 -26 2Total
  • 75. 74 2012 $M 2015 $M Growth % Clear lens 46 63 +37% Cosmetic lens 12 28 +131% Lens care 21 35 +61% Total vision care 79 125 +58% Growth is driven by all three segments China vision care business
  • 76. 75 46 49 54 63 - 10 20 30 40 50 60 70 2012 2013 2014 2015 Clear lens revenue Clear lens portfolio ▪ Diverse full modality portfolio (daily to yearly), different materials (hema /sihy /hypergel), spherical and toric Drivers of growth ▪ Introducing innovative premium products while continuing to grow user base of long modality lenses ▪ Professional training to ECPs on toric and multifocal $ $ $ $ $ $ $ M M M M M M M CAGR: 11%
  • 77. 76 ▪ Segment market with multiple offerings and pack sizes Lens care portfolio 21 24 28 35 - 5 10 15 20 25 30 35 40 2012 2013 2014 2015 Lens care revenue Drivers of growth ▪ Cross-sell with lens to maximize B+L strong brand equity $ $ $ $ $ $ $ M M M M M M M $ M CAGR: 17%
  • 78. 77 Cosmetic lens portfolio 12 19 23 28 - 5 10 15 20 25 30 2012 2013 2014 2015 Cosmetic lens revenue ▪ Positioning cosmetic lens as beauty necessity, and B+L as trend setter Drivers of growth ▪ Variety of patterns and colors, along with full modality offeringsCAGR: 32%$ $ $ $ $ M M M M M $ M
  • 79. 78 ▪ Best-in-class team and talent pipeline for future growth ▪ Stable, passionate sales force committed to growing with customers and consistently delivering results, which exceed expectations ▪ Robust local portfolio to meet the diverse consumer needs ▪ Insights into customer needs, values, and behavior drive the development of successful local marketing campaigns ▪ Content-based digital social media model is proven to be effective and cost efficient Valeant’s decentralized model has enabled China business to grow faster than competition We have a distinctive commercial model
  • 80. 79 Our pipeline in China is set up to fuel further growth 2015 2016 2017-2019 XUV-005 (Lubricant) XUV-011 (Multifocal) XUV-002 (Color) XUV-014 (Multifocal) XUV-004 (Single vision spherical) XUV-008 (Lubricant) XUV-007 (Multifocal) XUV-001 (Cosmetic)  Biotrue ONEday  PureVision2 Toric  Bescon half yearly cosmetic lens  Bescon half yearly clear lens 2017-2019 NPD Pipeline
  • 81. 80 Joseph Gordon: General Manager, Consumer Health Care Background ▪ 28 years in OTC Health Care ▪ Valeant / B+L (5 years) ▪ Wyeth (19 years) – VP, Sales – VP, Marketing, Advil – GM, Nutritionals Business Unit ▪ GSK (5 years) Education ▪ B.A. Economics, Rutgers University
  • 82. 81 Valeant Consumer Healthcare drivers of growth ▪ Strong and diverse portfolio of products ▪ Exceptional retailer relationships ▪ Consumer marketing expertise and effectiveness ▪ Drive recommendations through detailing of: dermatologists, ophthalmologists, and optometrists ▪ Physicians’ intimate involvement in our product development process
  • 83. 82 -2.0 -1.6 -0.4 1.0 1.41.5 2.8 4.5 5.3 5.7 6.6 7.67.77.9 9.8 Valeant is one of the fastest growing US consumer healthcare companies Source: IRI Market Advantage Fastest growing US consumer healthcare companies (3-year CAGR)1, % 1 CAGR calculation based on retail sales; Total US 3 year CAGR for latest 52 weeks ending 11-29-2015. Based on biggest manufacturers in Healthcare. Excludes private Label. 2 Alcon growth figures have been disaggregated from Novartis 2
  • 84. 83 Valeant has a strong portfolio of consumer products Skin Care Eye Care Eye Vitamins
  • 85. 84 Important relationships with key leading retailers Strong account management Effective customer marketing Private label Eye Care category captain
  • 86. 85 Comprehensive marketing approach Print Digital / social media ProfessionalTelevision Integrated and diverse consumer marketing
  • 87. 86 Consumer Marketing: PreserVision ▪ 88% share of the AREDS vitamin market ▪ First to market with AREDS 2 formula ▪ AREDS clinically proven ▪ Estimated 7M+ diagnosed non-users (growth opportunity) Net sales Source: IRI data, NEI incidence and prevalence data 15 $100M $80M 14 $72M $113M 2012 2016E $140M 2013 +8% +15% +17% +20% AREDS 2 Launch Q4 TV Campaign Launch Consumer Print TV Campaign (continued) Retail consumption growth
  • 89. 88 Biotrue is the fastest growing multipurpose contact solution brand Biotrue net sales 2013 $63M $41M 2015 $46M $76M 2016 E2012 2014 $88M Source: IRI data Biotrue Challenge re-launched CAGR (2012 – 2015) ▪ Biotrue: 23% ▪ Category: 1%
  • 90. 89 Biotrue fast facts New users who took the Biotrue Challenge Doctors’ primary recommendation 1 Million 1/3 #1 Contact lens solution at Walmart Biotrue contact lens solution works like your own eyes – 20 hours of moisture
  • 92. 91 Focusing on the professional ▪ Over 600 sales reps selling to dermatologists, optometrists, and ophthalmologists ▪ Reps have reached 10,000 dermatologists, distributing 15 million samples ▪ CeraVe #1 dermatologist recommended moisturizing brand Source: Valeant sales force productivity, Symphony Health Survey of Dermatologists
  • 93. 92 CeraVe has been the fastest growing skincare brand for four straight years 2016 E $88M 2015 $114M 2014 $135M 12 $50M 2013 $69M CeraVe core products CeraVe new products Net Sales Competitive Trends (2013-2015 CAGR) 24% 8% 3% ▪ Professional support and involvement has driven commercial success ▪ Growth sustained in both core and new products Category 1% Source: IRI data
  • 94. 93 CeraVe has generated a digital buzz on Facebook, boosting viral impressions by 600% “The CeraVe Moisturizing Lotion and Hydrating Cleanser are just the best products out there” - Kathy M. “I love your Foaming Facial Cleanser but have recently fallen in love with your Baby Wash & Shampoo to clean my face during the Winter!” - Diana D. “My allergist insisted I use CeraVe…I had no idea they had so many products!” - Christie C. “My dermatologist recommended CeraVe Skincare to me yesterday…I’m really looking forward to trying it out!” - Emily M. “Seriously, CeraVe is the best product ever. Totally obsessed and refuse to use anything else. I use the lotion, the wash, all of it. Great stuff.” - Melissa M. “Just bought the am/pm lotion today and I love it, my face is so soft and smooth…” - April M.
  • 95. 94 Creating long-term growth Recent 2016 2017 2018 Healing ointment1 Skin Care Eye Care Eye Vita- mins  CeraVe Baby  CeraVe Sun  CeraVe anti- aging  CeraVe cleansing bar  Peroxiclear  SootheXP  AREDS 2 Body wash Anti-itch AREDS 2 multivitamin Targeted therapies Project ‘lightbulb’ Dry Eye extension Core upgrades / claims Product upgrade Project ‘moisture’ AREDS 2 advanced Note: Position of star in box does not reflect anticipated launch timing within a given year 1 All pipeline skin care products planned as part of the CeraVe family Product upgrade Select product pipeline and launches
  • 96. 95 Valeant consumer healthcare company is poised to continue its strong growth trajectory ~$540M 2013 2015 ~$625M 2014 ~$590M Valeant US consumer healthcare revenues High single- digit growth expected in 2016
  • 97. 96 Fernando Zarate General Manager, Valeant Mexico, Andean region, Central America and Caribbean (CAC) Background Education ▪ 24 years in Pharma industry ▪ Valeant-Mexico; General Manager (8 years) ▪ Teva (3+ years) – OTC-Consumer Business Director ▪ Schering Plough (3+ years) – Pharma Division Director ▪ SmithKline Beecham (7+ years) – Consumer business Commercial Director (Venezuela- Andean) – Commercial Director (Mexico) ▪ M.B.A., IPADE Business School Administration ▪ B.A., Iberoamericana University (Mexico City)
  • 98. 97 Mexico, Central America, Andean Revenue (Constant US$) Strong growth across all businesses $17M $20M Generics (Branded Generics)1 $228M Innovative (Rx) 201522014 $199M $14M $56M Device OTC $23M $109M $64M $124M 2 2015 data actual through Oct., on track to outperform forecast for Nov. and Dec. 18% 16% 14% 15% Growth’14-’15 1 ~90% of generics in Mexico & Andean region sold as Branded Generics 15% growth overall
  • 99. 98 Branded generics success in region depends on four defining features Well-known local brands with strong reputation for quality ▪ Trusted company names: Atlantis, Tecnofarma, Grossman Local manufacturing skill and agility ▪ Two local manufacturing facilities with internal capability to produce injectables, oral solids, topical, liquids ▪ ~800 manufacturing employees producing 30M units/year (30% YOY growth) Proven commercial model with direct distribution ▪ ~600 sales employees drive distinctive level of geographic coverage (92%) ▪ ~45% of sales through direct distribution channels First-to-market advantage driven by local R&D ▪ Mexico R&D team: 32 professionals ▪ 9 mo. for Valeant vs. 2-3 years for competitors to launch new BGx
  • 100. 99 Mexico, Andean region, Central America and Caribbean branded generics pipeline We have plans to release many new branded generics in the next few years to supplement strong growth in existing offerings 20172015 Spagnosan (osteoporosis) Ciscotan (glaucoma) Sotoldor (glaucoma) XUG-002 (glaucoma) 2016 XUG-012 (vaginal infections) XUG-011 (anti-inflammatory) XUG-001 (joint pain, RA) XUG-003 (antifungal) XUG-004 (oral inflammatory disorders) XUG-010 (ocular lubricant) XUG-013 (vaginal infections)    Select product pipeline and launches
  • 101. 100 Dr. Tage Ramakrishna Chief Medical Officer, Head of R&D and Quality Background Education ▪ Valeant Pharmaceuticals (4 years) – Chief Medical officer, Head of R&D and Quality ▪ Progenics Pharmaceuticals (4 years) – VP Clinical Research ▪ Nycomed (formerly Altana) (5 years) – Corporate VP International Drug Safety ▪ Insmed, Inc. – Medical Director ▪ Degge Group – Pharmacovigilance Consultant ▪ M.D., Karol Marcinkowski University of Medicine ▪ Medical College of Virginia ▪ B.A. in Biology, Rutgers University
  • 103. 102 Valeant R&D at a glance 200+active US programs + + 6 NDAs approved in last three years 43R&D facilities 13 510K and PMA approvals in last three years 100MD, PHD, PharmD, JD and DMD degrees 1,000R&D and quality employees
  • 104. 103 R&D: Key messages Our robust pipeline positions us well for future growth We are excited about our numerous upcoming launches We have a strong track record of launching products We are the most productive R&D organization in the industry We have a distinctive R&D model with high quality people
  • 105. 104 Our R&D activities look similar to other Pharma companies… ▪ Study design leveraging TA expertise ▪ Input from KOLs and customers throughout the development process ▪ Collaboration between R&D and commercial ▪ Outsourcing rather than fixed infrastructure ▪ Internal expertise in regulatory, pharmacovigilance, quality, and medical affairs
  • 106. 105 Our execution of R&D makes our model distinctive Eliminate non-value added bureaucracy Partner with third parties to leverage capabilities Empower individuals and regions to make their own decisions Terminate non-promising assets early, based on data Take actions when needed, rather than waiting for committees Embrace incremental as well as transformative innovation Outside experts participate in key decision meetings (e.g., portfolio reviews)
  • 107. 106 Our productivity is higher than peers Source: Evaluate Pharma, FDA, Capital IQ, Annual reports, Press search 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.3 0.3 0.3 0.5 1.2 2.1 Top 15 average 3.02 1 Refers to New Molecular Entity and Biologic License Application 2 Does not include Contact lenses and surgical devices. Does not include B+L and Salix approved products (Fulyzaq, Bepreve and Besivance) that were not developed under the Valeant model; all other companies include acquired brands, which overstates their productivity “ ” Innovation has nothing to do with how many R&D dollars you have. When Apple came up with the Mac, IBM was spending at least 100 times more on R&D. It's not about money. It's about the people you have, how you're led, and how much you get it - Steve Jobs R&D Productivity for 15 PharmaCos with most approvals - 2009-’14 # of NMEs/BLAs1 per $B R&D spend
  • 108. 107 We believe we are significantly more successful at developing products than the industry Source: Pharmaprojects 2014, Management Estimates 1 Average of all competitors from 2010-2014 2 2011-2015 Valeant’s success rate in dermatology2 20%18% 55% 100% 56% 69% Ph. II Ph. IIIPh. I Valeant2 Industry1 Success rates in dermatology
  • 109. 108 Global product launches Source: Management estimates 32 131218+32 Product launches1, 2014-’15 1 Includes global line products launched in Ex-US markets 76
  • 110. 109 How our R&D pipeline was built We continue to invest in TAs with attractive assets We have acquired new platforms and capabilities in attractive TAs In Dermatology, we have built capabilities from discovery to commercialization Our selection and portfolio de-risking give us an advantage Post-acquisition, we have supplemented the pipeline where required and de-risked where possible We are building similar capabilities in Ophthalmology and GI Internal Inherited In-licensed / purchased Brodalumab
  • 111. 110 We have dramatically expanded our significant US R&D programs 1 US programs only; Includes generics; excludes 90+ programs related to post marketing commitments and other small programs 2 Prior to acquisitions in TA (e.g., B+L in 2013 and Salix in 2015) 3 Includes aesthetics, women’s health, and generics Dec. 20151Dec. 2010 Surgical 32N/A2 17Consumer 26 Dermatology 9 15 Contact lenses 9N/A2 Ophthalmology 1 7 GI 6N/A2 Others3 5 17 Total 32 112
  • 112. 111 We have good depth of early and late assets across TAs 1 Prior to Phase III for Pharma, 2018+ expected launch for others 2 Includes Phase III and FDA submitted products 3 Includes aesthetics, women’s health, and generics 8 4 12 6 4 5 7 22 6 20 3 2 12 1Opthalmology 7 Contact lenses 9 GI 6 Others3 17 Surgical Dermatology 15 26Consumer 32 40 early 72 late 112 total Early1 Late2 Significant active US programs as of Dec. 2015
  • 113. 112 US prescription and generic drugs pipeline Ophthalmology GenericsDermatology GI In-house developmentWomen’s health Early stage (Pre Ph. III) Late stage (Ph. III - submission) Latanoprostene Bunod: OAG IDP-118: PsoriasisSAL-020: HAE IDP-120: Acne IDP-121: AcneSAL-021: RA IDP-125: Actinic keratosis Relistor Oral: Opioid induced constipation IDP-124: Atopic dermatitis IDP-131: PsoriasisSAL-022: Diabetes IDP-126: Acne IDP-122: Psoriasis SAL-024: Crohn’s SAL-023: Cirrhosis BLG023: Anti-infective IDP-127: Anti-fungal IDP-123: Acne Brinzolamide Gx: OAG BLO-020: Inflammation IDP-128: Actinic keratosis VAL-BRO-03: Psoriatic arthritisSPT-201: HSDD BLG020: Disclosing agent IDP-129: Acne Brodalumab: Psoriasis BLG021: Anti-infective IDP-130: Acne BLO-021: Cystoid Macular edema BLG022: Anesthetic EGP-437: Anterior uveitis BLO-022: Post-operative inflammation
  • 114. 113 US OTC pipeline CER-008: Lotion CER-007: Lotion CER-006: Wash CER-009: Lotion CER-005: Wash CER-004: Ointment CER-003: Oil CER-002: Cream CER-001: Oil PUR-004: Bar PUR-003: Wash PUR-002: Wash PUR-006: Cream PUR-005: Cream PUR-001: Wash STS-001: Spray CAL-001: Spray ACF-002: Device ACF-001: Lotion BLO-026: Dry eye OBG-006: Kit BLO-024: Nutritional BLO-023: Nutritional BLO-025: Nutritional OBG-005: Cleanser OBG-004: Reformulation OBG-003: Sunscreen OBG-002: Skin lightener OBG-001: Cleanser BLO-029: Disinfectant BLO-030: Disinfectant BLO-028: Lubricant BLO-027: Lubricant Early stage Late stage Aesthetics Dermatology Lens Care Ophthalmology In-house development Nutritionals BLO-031: Eye whitener
  • 115. 114 US Devices pipeline Aesthetics Contact lenses Surgical In-house development Late stageEarly stage BLS-021: Retina BLS-023: Retina BLS-022: Retina BLS-024: Retina BLS-026: Retina BLS-027: Retina BLS-028: Retina BLS-029: Retina BLS-030: Retina BLS-031: Retina BLS-025: Retina BLS-032: OEM SOF-010: Skin resurfacing SOT-010: Fine Lines & wrinkles SOT-011: Fine Lines & wrinkles BLS-002: Cataract BLS-003: Cataract BLS-004: Cataract BLS-005: Retina BLS-006: Cataract BLS-007: Cataract BLS-001: Cataract SOM-010 Vascular Lesions BLC-008: Astigmatism BLC-007: MF BLC-009: Astigmatism BLS-015:Cataract BLS-016: Cataract BLS-017: Therapeutics BLS-018: Retina BLS-019: Retina BLS-020: Retina BLS-014: Refractive BLC-001: SVS BLC-003: SVS/MF/fA BLC-002: SVS BLC-004: Toric BLC-006: SVS BLS-012: Retina BLS-008: Cataract BLS-009: Retina BLS-010: Cataract BLS-011: Cataract BLC-005: SVS/MF BLS-013: Retina
  • 116. 115 Ex-US pipeline Dermatology In-house developmentOphthalmology NutritionalsGenerics Women’s health Contact lenses 1 Excludes EU Generics (listed on the next page) Aesthetics Lens Care Surgical GI Early stage1 Late stage1 XUN-004: Nutritional XUN-003: Magnesium caps XUO-017: Lubricant XUV-001: Cosmetic XUN-002: Vitamins XUO-016: Lubricant XUV-006: Lubricant XUN-001: Nutitional XUO-015: Dry eye XUD-008: Second degree burns XUN-005: Nutritional XUO-018: Lubricant XUV-002: Cosmetic XUW-002: Osteoarthritis XUV-003: Aphakia XUG-002: OAGXUO-002: Glaucoma XUO-009: Glaucoma XUD-002: Sunscreen XUG-003: Anti-fungalXUO-003: Dry eye XUO-010: Conjunctivitis XUD-003: Lotion XUG-004: Oral Inflamatory Disorders XUO-004: Glaucoma XUO-011: Inflammation XUD-004: Device XUG-009: Hypertension XUO-005: Lubricant XUO-012: Corneal lesions XUD-005: Cosmetic XUG-001: RAXUO-001: Inflammation XUO-008: Dry eye XUD-001: cleanser XUO-006: Decongestant XUO-013: Conjunctivitis XUD-006: Onychomycosis XUO-014: Dry eye XUD-007: CosmeticsXUO-007: Decongestant XUV-004: SVS XUW-001: HSDD XUV-005: LubricantXUA-001: Hair removal LAV-006: Lubricant LAV-001: Aphakia XUI-001: IBS-D XUD-009: Emollient XUN-006: Nutitional XUN-007: Nutritional XUV-007: MF XUV-011: MF XUV-008: Lubricant XUV-009: SVS XUV-010: Astigmatism XUV-012: SVS XUV-013: Astigmatism XUV-014: Presbyopia XUV-015: MF XUG-006: Diabetes XUG-007: Hypertension XUG-008: Hypertension XUG-005: Cholestrol XUG-013: Vaginal Infections XUG-010: Ocular lubricant XUG-011: Anti-Inflammatory XUG-012: Vaginal Infections
  • 117. 116 EU generics pipeline In-house development Early stage Late stage EUG-012: Glaucoma EUG-044: 0 EUG-070: Copd EUG-095: GlaucomaEUG-026: Local hemostasis EUG-013: Glaucoma EUG-045: Benign prostatic hyperplasia EUG-071: Asthma EUG-096: Glaucoma EUG-027: Prevention of deep vein thrombosis EUG-046: Benign prostatic hyperplasia EUG-079: Allergy EUG-097: Glaucoma EUG-028: Chronic nevous insufficiency EUG-047: Rheumatoid arthritis EUG-080: Allergy EUG-098: Eye infections EUG-029: Chronic nevous insufficiency EUG-048: Osteoporosis EUG-081: Pain EUG-099: GlaucomaEUG-030: Hypertension EUG-051: Bacterial infections EUG-082: Eye vitamins EUG-100: GlaucomaEUG-031: Hypertension EUG-052: Cell lung cancer EUG-083: Allergy EUG-101: Glaucoma EUG-032: Hypertension, heart failure EUG-057: Mlaignant melanoma EUG-033: Hypertension, heart failure EUG-001: Hypertension EUG-034: Hypertension EUG-059: Lung and pancreatic cancer EUG-086: Adrenocortical insufficiency EUG-014: Antispasmotic EUG-002: Acne vulgaris EUG-035: Angina pectoris EUG-060: Pain EUG-087: Dry eyeEUG-015: Hypertension EUG-003: Atopic dermatitis EUG-036: Hypercholesterolemia EUG-061: Pain EUG-088: Eye inflamationEUG-016: Dermtitis EUG-004: Acne vulgaris EUG-037: Hypercholesterolemia EUG-064: Schisofrenia EUG-089: Eye inflamationEUG-017: Antiseptic EUG-005: Acne vulgaris EUG-038: Prevention of blod clots EUG-065: Schisofrenia EUG-090: Dry eyeEUG-018: Cough and cold EUG-006: Hypertension EUG-039: Whitenning cream EUG-066: Pain EUG-091: Eye infectionsEUG-019: Eye inflamation EUG-009: Dermatitis EUG-040: Cosmetics EUG-067: Pain EUG-092: Eye inflammation EUG-020: Chemotherapy induced nauzea EUG-010: Severe acne EUG-041: Atopic dermatitis EUG-068: Cough and cold EUG-093: AllergyEUG-021: Type II diabetes EUG-011: Hyperuricemia EUG-042: Bacterial skin lesions EUG-069: Asthma, copd EUG-094: Dry eye EUG-022: Haemorrhoids - early stage EUG-084: Glaucoma EUG-058: Myeloma EUG-085: Allergic conjuctivitis Generics
  • 118. 117 Select pipeline opportunities Brodalumab Relistor Oral Latanoprostene Bunod (LBN) Drug1 Indication Expected launch US Prevalence Opioid induced constipation (OIC) with chronic non- cancer pain 2017/18IDP118 Moderate to severe plaque psoriasis Reduction of Intraocular pressure in patients with Open Angle Glaucoma (OAG) and Ocular hypertension 2016 2016 2016 ~9.5M ~3.7M ~3.0M Source: Decision Resources, BioMed Tracker Moderate to severe plaque psoriasis ~9.5M 1 Product candidates, not yet approved by the FDA
  • 119. 118 Relistor Oral could be a new option for patients suffering from opioid induced constipation (OIC) with chronic non-cancer pain Source: Digestive Disease Week, 2012 (R. Rauck, J.Peppin, R.Israel, J. Carpentino, J.Cohn, S.Huang, E.Bortley, C.Paterson, W.Forbes) 1 Peripherally acting, selective μ-opioid receptor antagonist with restricted CNS penetration 2 Product candidate, not yet approved by the FDA 3 Rescue-free bowel movement - defined as a bowel movement that occurred without laxative use (i.e., no laxative use within 24 hrs prior to the bowel movement); tested for within 4 hours of dosing during daily dosing period 4 Severe adverse events 27.424.6 18.1 MNTX 450 mgMNTX 300 mgPlacebo 28.9 9.4 Placebo 12 mg QD MNTX 3201 Oral formulation Primary Efficacy Endpoint (% of respondents1) MNTX 3356 SC Formulation Co-Primary Efficacy Endpoint ▪ Subcutaneous injection currently approved for OIC in patients with advanced illness and chronic non- cancer pain ▪ Oral methylnaltrexone2 300 mg and 450 mg significantly increased the percentage of patients with a RFBM3 within 4 hours ▪ Incidence of SAEs4 was 3% in the all tested groups versus 4% in the placebo group
  • 120. 119 Latanoprostene Bunod (LBN) ophthalmic solution (0.024%) combines Latanoprost and Nitric Oxide in a single molecule to lower Intraocular pressure (IOP) LBN will be the first novel OAG monotherapy approved in 20 years: ▪ Nitric oxide plays a key role in numerous functions throughout the body including many well documented functions in the healthy eye1 ▪ Glaucoma patients have lower levels of ocular nitric oxide than those observed in normal eyes2,3 ▪ LBN4 lowers IOP by increasing outflow through both the uveoscleral and trabecular meshwork pathways ▪ PDUFA date – July 21st 2016 1 Culotta E, et al. Science. 1992;258:1862-5 2 Nathanson JA, et al. Invest Ophthalmol Vis Sci. 1995;36:1774-84 3 Galassi F, et al. Br J Ophthalmol. 2004;88:757-760 4 Product candidate, not yet approved by the FDA Source: Mayo Clinic Open Angle Glaucoma (OAG)
  • 121. 120 Clinical Studies Support Viability of LBN (1/2) Summary of Phase II results Reduction in mean diurnal IOP on day 7, 14 and 28 9.0 8.9 8.3 7.8 7.7 7.3 Day 14 Day 28Day 7 Latanoprostene bunod 0.024% Latanoprost 0.005% P = 0.033 P = 0.015 P = 0.005 In a Phase II dose-ranging study, LBN3 showed positive results including consistently better control of IOP over 28 days as well as a statistically significant greater percentage of responders vs. latanoprost 0.005%1,2 1 Defined as patients achieving an IOP ≤18 mm Hg 2 Weinreb RH, et al. Br J Ophthalmology. 2015;99:738-45 3 Product candidate, not yet approved by the FDA
  • 122. 121 Clinical Studies Support Viability of LBN (2/2) Summary of results of two phase III pivotal studies ▪ In two phase III studies LBN provided a mean IOP reduction of 7.5-9.1 mm Hg over three months of treatment (statistically superior to timolol between 2 and 12 weeks)1 ▪ LBN3 was safe and well tolerated with no significant adverse events.1,2 Rates for hyperemia were comparable to latanoprost2 1 Data on file 2 Weinreb RH, et al. Br J Ophthalmology. 2015;99:738-45 3 Product candidate, not yet approved by the FDA
  • 123. 122 R. Todd Plott, MD Dermatologist Background ▪ 16 years in the pharmaceutical drug development including at Medicis Pharmaceuticals ▪ Led the development of Solodyn, Vanos, Ziana, Loprox Shampoo and Ammunol while at Medicis ▪ Over the past 5 years, in solo dermatology practice in Ft Worth, TX ▪ Unpaid (expenses only paid) Valeant R&D consultant; holds no Valeant stock Education ▪ University of Texas Medical Branch Galveston, M.D. ▪ University of Arkansas Heath Sciences - Intern and Dermatology Residency ▪ National Cancer Institute - Fellowship
  • 124. 123 • Patients have a medical need for the unique dermatology drug products that manufacturers provide • Access to these drugs can be a problem • Many manufacturers offer drug assistance programs for patients • Drug assistance programs have been very helpful to patients • Patients do better when they get the medications that they need My observations
  • 125. 124 IDP118 – Topical Treatment of Psoriasis ▪A combination topical drug product1 containing and retinoid and a steroid ▪Phase II clinical results suggest the combination is superior to the individual components ▪Expected completion Phase III Studies - Q4 2016 1 Product candidate; not yet approved by the FDA
  • 126. 125 Brodalumab is an anti–interleukin-17 receptor-A mAB that could address moderate-to-severe psoriasis ▪ Brodalumab 210 mg was superior to placebo and to ustekinumab1 in treatment of moderate-to-severe psoriasis ▪ Symptoms of psoriasis reduced ~2x faster than the median response time with ustekinumab (4.1 weeks vs. 8.1 weeks)2 ▪ Results for Brodalumab3 210 mg were confirmed in two phase III studies Source: New England Journal of Medicine (M. Lebwohl, B. Strober, A. Menter) 1 At week 12, PASI 75 response rates were significantly higher with brodalumab at a dose of 210 mg and at a dose of 140 mg than with placebo 2 Tested median time to a PASI 75 response for patient arm given 210 mg of brodalumab every 2 week 3 Product candidate, not yet approved by the FDA PASI 75 response PASI 100 response 0 50 100 69% 09 6% 1205 85% 10 Week 69% Response rate (%) 110706 080402 031 0 50 100 03 1004 080705 0.3% 19% 02 0906 111 Response rate (%) Week 12 37% 27%
  • 127. 126 Looking forward ▪ We have a history of successes across key therapeutic areas ▪ We have intelligently invested in R&D to build a deep and exciting pipeline ▪ I am passionate about our R&D model and strategy, and confident about the future
  • 128. 127 Drivers of Valeant’s success Our decentralized model and talented people, which give us a competitive edge (speed of decision making and in- depth customer knowledge) Our collection of great healthcare brands around the world Our innovative strategies (often disruptive), which have challenged industry convention Our relentless focus on providing easy and affordable access for physicians and patients Our exceptionally productive approach to R&D
  • 129. 128 EMT J. Michael Pearson Chairman of the Board and Chief Executive Officer Robert Chai-Onn Executive Vice President, General Counsel and Chief Legal Officer Robert Rosiello Executive Vice President and Chief Financial Officer Dr. Pavel Mirovsky President and General Manager, Europe Dr. Ari Kellen Executive Vice President/Company Group Chairman Anne Whitaker Executive Vice President/Company Group Chairman Deb Jorn Executive Vice President Dermatology and GI Tom Appio Sr. Vice President - Asia Pacific, Managing Director, China
  • 130. 129 Senior Management Team Panel J. Michael Pearson Chairman of the Board and Chief Executive Officer Robert Rosiello Executive Vice President and Chief Financial Officer Dr. Pavel Mirovsky President and General Manager, Europe Dr. Ari Kellen Executive Vice President/Company Group Chairman Anne Whitaker Executive Vice President/Company Group Chairman Deb Jorn Executive Vice President Dermatology and GI Tanya Carro Senior Vice President, Finance and Corporate Controller Dr. Tage Ramakrishna Chief Medical Officer, Head of R&D and Quality Tracy Valorie Senior Vice President and General Manager, Women’s Health and Bausch + Lomb Pharmaceutical Division
  • 132. 131 To supplement the financial measures prepared in accordance with U.S. generally accepted accounting principles (GAAP), the company uses the following non-GAAP financial measures: Adjusted EPS, non-GAAP revenue, non-GAAP cost of goods, non-GAAP selling, general and administrative expenses, Adjusted Cash flow from Operations. Reconciliations of these non-GAAP financial measures to their most directly comparable GAAP financial measure can be found in our earnings release and Form 8-K on Tables 2 through 2b, Table 3, Table 4 and Table 5.2, respectively. A copy of the earnings release, including financial schedules, is posted on the “Investors” section of the Valeant.com website. In addition, Adjusted EBITDA is a non-GAAP financial measure that will be provided in our earnings releases and Form 8-K going forward. The Company does not provide guidance with respect to GAAP financial measures other than revenues or provide reconciliations to GAAP of its forward-looking [non-GAAP financial measures] due to the inherent difficulty in quantifying certain amounts that would be required to be included in the GAAP measure of earnings per share due to their unknown effect, timing and potential significance. Examples of these items include impairments of assets, gains and losses from the extinguishment of debt, legal settlements, purchases of in-process research and development assets, and gains and losses from asset sales. Accordingly, the GAAP calculation of projected net income (loss) is not available for Valeant without unreasonable efforts. By disclosing the non-GAAP financial measures referenced above, management intends to provide investors with a meaningful, consistent comparison of the company’s baseline operating results and trends for the periods presented by excluding items that are considered by the company not to be reflective of the company’s ongoing results. Management uses all of the above named non-GAAP financial measures internally for strategic decision making, forecasting future results and evaluating current performance. [For example: to set internal budgets, evaluating company performance, setting incentive compensation targets and planning and forecasting of future periods] Non-GAAP financial measures are not prepared in accordance with GAAP. Therefore, the information is not necessarily comparable to other companies and should be considered as a supplement to, not a substitute for, or superior to, the corresponding measures calculated in accordance with GAAP. Definition of terms
  • 133. 132 Adjusted EPS* (non-GAAP) multiplied by Shares Outstanding Add: Taxes Interest Share Based Compensation Depreciation Adjusted EBITDA* Note: Adjusted EBITDA as defined in our Credit Agreement excludes certain charges and includes certain pro forma adjustments for acquisitions and divestitures. Details of the Adjusted EBITDA calculations per our Credit Agreement can be found in our Credit Agreement, which is filed as an exhibit to our 10-K and can be found in the investor relations section of the Valeant website. * See Page* Non-GAAP Adjusted EBITDA calculation