Q-Fiesta Biochem 2019

1. Q-FIESTA BIOCHEM

2. Q-FIESTA BIOCHEM
BIOCHEMISTRY QUIZ 2019
25.01.2019
DEPT OF BIOCHEMISTRY, IMS & SUM
HOSPITAL
SIKSHA ‘O’ANUSANDHAN UNIVERSITY
BHUBANESWAR

3. QUIZ MASTERS
Prof DrViyatprajna Acharya
MBBS, MD, PhD
Dr Sarthak Ranjan Nayak
Assoc. Prof. MBBS, MD

4. Scorer- Dr. Pragya Panda Moderator- Dr Swarup Ku. Panda

5. General round (Direct & MCQ)
Visual round (2)
Step ladder question round
Chapter specific round
Clinical question round
Rapid Fire Round

6. GENERAL ROUND-I

7. 1
In DNA, the two strands are held
together by which type of bond?

8. 2
What is the normal A: G ratio?

9. 3
Name an ecto -enzyme.

10. 4
Major enzyme deficient in
Galactosaemia is ?
?
?
?
?

11. 5
If enthalpy is the measure of
heat content,
the entropy is the measure of
----?

12. 6
Collagen triple helix has ------ level of
structural organisation of protein.

13. Audience
Which phospholipid is involved
in apoptosis?

14. GENERAL ROUND-II
(NO PASS)

15. 1
The following is true about
Glucokinase
a) It is secreted by the Pancreas
b) It has high Km for glucose
c) It is not specific for glucose
d) All its functions can be done by Hexokinase

16. 2
2. All are true about Vitamin E except
a) Rich source is Palm oil
b) Transported by Chylomicrons
c) Isolated from Wheat germ oil
d) Ionone ring with Isoprenoid side chain

17. 3
3. Glucose enters muscle cells mostly
by:
a) simple diffusion
b) facilitated diffusion using a specific
glucose transporter
c) co-transport with sodium
d) active transport

18. 4
4. Pairs of electrons carried in the form,
FADH2 and NADH+ + H+, collectively contain
enough free energy to rephosphorylate :
a) 4 ATP
b) 5 ATP
c) 6ATP
d) 7 ATP

19. 5
Methotrexate is an antagonist of -
(i) Riboflavin
(ii) Folic acid
(iii)Thiamine
(iv) Cobalamine

20. 6
In Non-competitive inhibition,
(i) V max unchanged
(ii) Km unchanged
(iii)V max increased
(iv) Km decreased

21. Audience
In essential pentosuria, urine contains -
(i) D-Ribose
(ii) D-Xylose
(iii) L-Xylose
(iv) L-Xylulose

23. Visual round

24. 1

25. 2

26. 3

27. 4

28. 5

29. 6

30. Audience
 Identify the
scientist who has
contributed to
almost all the
fields of
Biochemistry.
 In 1902 he won a
Noble Prize too.

31. WHO AM I???

32. 1

33. 2

34. 3

35. 4

36. 5

37. 6

38. Audience

39. What’s the score ???

40. STEP LADDER QUESTION
ROUND

41. 1
(i) I am a tripeptide involved in the
elimination of free radicals
(ii) I am a co-substrate for some enzymes.
(iii) I act as a conjugating agent too.
(iv) Out of my 3 amino acids 2 are
glycine and glutamate

42. 2
(i) I am a vitamin resembling a
carbohydrate
(ii) I am not synthesized in man & higher primates.
(iii) I am needed for hydroxylation of
lysine and Proline
(iv) Without me, people have bleeding
gums, delayed healing of wounds and
hypochromic microcytic anemia…

43. 3
(i) I am a reducing equivalent present in
RBC
(ii) I maintain RBC membrane integrity
(iii) I keep glutathione in reduced state
(iv) I am produced by HMP shunt

44. 4
(i) I am an organelle known as
microbody
(ii) My marker enzyme is Catalase
(iii) I am involved inVLCFA metabolism
(iv) I remove unwanted peroxides and
free radicals from the cell.

45. 5
I am a chemical substance formed as an intermediate
in glycolytic pathway only present in RBC.
My level in blood goes up when you
climb up a mountain/ high altitude.
I help in energy economy of RBC.
I help to unload oxygen from haemoglobin to
the tissues

46. 6
I am a heat stable B complex vitamin having
chemical composition pyridine 3- carboxylic
acid
I’m synthesised from an amino acid
I can produce transient cutaneous
vasodilatation on parenteral administration
I can lower lipid levels

47. Audience
I am a basic amino acid having pI
close to blood pH
I am found in chromosome
I contain an Imidazole group
Infants can’t synthesize me

48. Somemore…..
I am a polyunsaturated fatty acid present
in the biomembranes having 20 C atoms
I belong to Omega 6 family
I give rise to substances that can contract
uterus, secrete HCl from stomach and
stimulate bowel function.
I have 4 double bonds

50. Chapter specific
round

51. CARBOHYDRATE
What is fructosan?

52. Protein
Who got noble prize for
sequencing insulin?

53. Lipid
What is the significance of
DHA?

54. Vitamins
Vitamin B12 is absorbed from
which part of intestine?

55. Biological oxidation
 What is the mode of inheritance for
OXPHOS diseases (i.e. diseases
pertaining to mitochondrial
enzymes)

56. Enzymes
Which enzyme is most specific
for diagnosing acute
pancreatitis?

57. Nucleotide chemistry
What is the nucleoside
formed from hypoxanthine?

58. pH ,Acid base balance
What is the major intracellular
buffer ?

60. CLINICAL QUESTION
ROUND

61. 1
A 25 year old female was admitted in
causality with severe dehydration and
vomiting. Her Random blood sugar was
found to be 350 mg/dl. Urine acetone-
positive.

62. 2
A premature newborn baby presented with the
H/o profuse bleeding through nose and ears.
Lab reports shows his Prothrombin time was
prolonged and clotting time was delayed.
Which vitamin may be deficient?

63. 3
Following a meal of skimmed milk and
yogurt, an adult female patient
experiences bloating, nausea, cramping
and pain in the abdomen followed by
watery diarrhoea.This set of symptoms
is observed each time she consumes such
a meal.What can be the probable
diagnosis?

64. 4
A child came with lesions at the angle of
the mouth, refusing to feed. From the
history he was found to be under-
nourished. Which vitamin
supplementation may help the child?

65. 5
A 60 year old man presented at Orthopaedics clinic with
severe low back ache. He gave history of repeated
respiratory infections. On his urinary investigation
presence of Bence Jone’s protein was found. Serum
protein electrophoresis was ordered to confirm the
diagnosis. What can be the probable diagnosis?

66. 6
A person suffering from malaria
took Primaquin and was brought
to the hospital with severe
haemolytic crisis. What can be
the probable enzymatic defect ?

67. 7
A girl came with complains of blurred
vision after the onset of evening. On
examination a triangular silvery-white
spot was found on the lateral side of the
cornea. Which vitamin supplementation
may help the girl?

68. 8
A young patient presented with chest
pain. Lab report shows his blood
cholesterol was 350mg/dl. His
father’s report also revealed
cholesterol at 400 mg/dl.

69. SCCCCCCCCCCCCOOOOOOORRRREEEE
?
?
?

70. Rapid Fire Round

71. 1
01. Mannose supplies energy to the sperm
in the Seminal fluid –T / F?
02. Na+-K+ ATPase is the marker for
plasma membrane–T / F?
03. Normal serum AST level is 5-40 mg/dl
–T / F?
04. Primary structure of protein has
sulfide bridges ……T/ F
05. Allopurinol action is an example of
suicide inhibition –T / F?

72. 2
01. pI of casein 5.4–T / F?
02. Which RNA is known as molecular
scissor?
03. Keratan sulfate doesn’t contain uronic
acid –T / F?
04. Post- prandial lipaemia is due to
presence of LDL-C in blood –T / F?
05. AA present in turns and bends of
protein-----

73. 3
01. In AMI, LDH-5 rises first in blood ….T/ F
02. Which is not a serine protease out of
the following…(i) Pepsin (ii) Trypsin
(iii) Chymotrypsin (iv) Clotting factors
03. Xanthoproteic test is used to detect
Arginine –T / F?
04. Homocystinuria can be caused by folate
deficiency –T / F?
05. Aconitase enzyme is inhibited by fluoride
in Glycolysis –T / F?

74. 4
01. 47 carbon atoms are there
in cholesterol –T / F
02. Schilling test is done to diagnose
vitamin B12 deficiency–T / F?
03. Linolenic acid belongs to ω3 FA –T / F?
04. CO inhibits……………..complex of ETC?
05. “A”- DNA is abundantly
seen in nature –T / F?

75. 5
01. Mitochondrial DNA has 20 tRNA–T / F?
02. Discoverer of “Burning feet syndrome”---
03. Stearic acid on beta-oxidation supplies
120 ATP---T/F?
04. What is the normal blood level of
ALT enzyme?
05. Acetoacetate is major circulating KB–T /
F?

76. 6
1. Leucine amino acid is purely
ketogenic –T / F?
02. Normal level of serum sodium is ……
03. CRP is an acute phase protein –T / F?
04. Regulatory enzyme of fatty acid
synthesis----
05. Storage form ofVit B12 is
methylcobalamine–T / F?

77. 7
01. Calcitriol is the major circulatory form of
Vitamin D–T / F?
02. Gamma rays are highest penetrating………….
T / F?
03. Tyrosinase contains which metal?
04. Key regulatory enzyme of glycogenolysis----
05. q & p are denoted for long and short arm of
chromosomes respectively –T / F?