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Modeling the Determinants of
Health in Complex Policy
Environments: A System Dynamics
Perspective
Aziza Mahamoud
Bob Gardner
February 14, 2013
Centre for Research on Inner City Health
1
Objective
• Background
• Introduction to simulation models and
system dynamics
• Overview of urban health model and user
interface
• Hands-on experience with using the urban
health model and interface
• Discussion
22/14/2014 | www.wellesleyinstitute.com
The Problem to Solve:
Systemic Health Inequities in Ontario
•there is a clear gradient in health
in which people with lower
income, education or other
indicators of social inequality and
exclusion tend to have poorer
health
•+ major differences between
women and men
•the gap between the health of
the best off and most
disadvantaged can be huge – and
damaging
•impact and severity of these
inequities can be concentrated in
particular populations and
neighbourhoods
35/28/2013 | www.wellesleyinstitute.com
these health inequities are based
in structured social and economic
inequality – social determinants of
health
• income inequality and poverty
• inequitable access to childcare
and early development resources
• precarious employment, unsafe
work
• racism, social exclusion
• inadequate and unaffordable
housing
• decaying social safety nets
45/28/2013 | www.wellesleyinstitute.com
Canadians With Chronic Conditions
Who Also Report Food Insecurity
5
We live in a world that is increasingly
more complex, dynamic &
interconnected
6
Better tools are needed to help us understand and
manage complexity!
5/28/2013 | www.wellesleyinstitute.com
Health Inequities = ‘Wicked’ Problems
• this means they are:
• shaped by many inter-related and inter-dependent factors
• in constantly changing social, economic, community and policy environments
• action has to be taken at multiple levels -- by many levels of
government, service providers, other stakeholders and communities
• solutions are not always clear and policy agreement can be difficult to achieve
• effects take years to show up
• have to be able to understand and navigate this complexity
to develop solutions
• we need to be able to:
• identify the connections between multiple factors → the key pathways to
change → the mechanisms or levers that drive change along these pathways
• specify the outcomes expected and the preconditions for achieving them
• understand how to deploy these levers in specific social, institutional and
policy contexts
75/28/2013 | www.wellesleyinstitute.com
Systems Approach at Wellesley
Institute
WI has been working with stakeholders to explore the
use of systems thinking and modeling to
• inform our understanding of the complexities of
the social determinants of health
• identify, assess and develop effective policy
alternatives to advance health equity
• consider how new approaches like this can be
informed by and connected to community
perspectives and policy needs
85/28/2013 | www.wellesleyinstitute.com
9
“All models are wrong, but some are useful”
5/28/2013 | www.wellesleyinstitute.com
George E. P. Box
Robustness in the Strategy of Scientific
Model Building, 1979
Why Develop Simulation Models?
• Systems are complex
• Help us be explicit about our mental models
• Theory building and testing
• A virtual world to design and assess
intervention strategies
• Tool for stakeholder engagement
• Identify gaps in our knowledge of how a
system works
105/28/2013 | www.wellesleyinstitute.com
Systems Dynamics: What is it?
• Field developed by Jay. W. Forrester at MIT in
the 1950s
• “The use of informal maps and formal models
with computer simulation to uncover and
understand endogenous sources of system
behavior” (Richardson, 2011)
Richardson, G.P. (2011). Reflections on the foundations of system
dynamics. System Dynamics Review, 27(3), 219-243.
115/28/2013 | www.wellesleyinstitute.com
System Dynamics Foundations
• Complexity science
• Focus on the whole rather than individual parts
• Interdependency
• Emergent behaviour
• Stock and flow
• Emphasis on feedback and non-linear thinking approach
to solving problems
• Provides tools and techniques that can help us:
• Study a system from various perspectives
• Look for emerging patterns and trends over time
• Examine causes of policy failures and unintended
consequences
• Identify effective ways of intervening (leverage points)
125/28/2013 | www.wellesleyinstitute.com
Problem
Definition
Identifying
Problem
Causes
Focus on Policy
Levers
Model
formulation, testi
ng & evaluation
Knowledge
Translation
Applying the System Dynamics Perspective
Mental
Model
135/28/2013 | www.wellesleyinstitute.com
Wellesley Urban Health Model
• a computer-based systems dynamics simulation
model
• helps us learn and understand the complex, and
dynamic interconnections between a select number
of health & social factors
• allows us to test what impact our decisions
(interventions) will likely have on population health
outcomes under various assumptions
• offers insight into how these effects could play out, and
over what timeframes
145/28/2013 | www.wellesleyinstitute.com
Model Framework
Population health outcomes
Death rate Disability Chronic illness
Social determinants of health interventions
Social cohesion
Health care
access
Affordable
housing
Income/jobs Behavioural
Changing health & social conditions
Adverse
Housing
Low
Income
Social
cohesion
unhealthy
behaviour
Poor health
care access
Disability
Chronic
illness
death
155/28/2013 | www.wellesleyinstitute.com
Model Scope
Population: City of Toronto
Distinguishes people by:
• Ethnicity (Black, White, E Asian, SW Asian, Other)
• Immigrant status (Recent, Established, Native-born)
• Gender
Captures:
• 5 areas of intervention: Healthcare access, Health
behavior, Income, Housing (lower & non-lower
income), Social cohesion
• Outcomes: Changes in overall deaths and health
conditions, and disparity ratios
Timeframe: 2006 – 2046
Age: 25-64
165/28/2013 | www.wellesleyinstitute.com
Outcome measures & definitions
Unhealthy behaviour & obese: the prevalence of people
who are smokers or obese (POWER 2009).
Chronic illness: having two or more of 12 chronic conditions
as specified by the Association of Public Health
Epidemiologists in Ontario (POWER 2009)
Access to health care: the ease of getting an appointment for
primary care
Disability: limitation in activities of daily living
Mortality: age-standardized death rate
Adverse housing: overcrowding (insufficient bedrooms)
Social cohesion: feeling “strong sense of community
belonging "
175/28/2013 | www.wellesleyinstitute.com
Data Sources and Parameter Estimation
All data or estimates broken out by 30 subgroups:
5 ethnicities x 3 immigrant statuses x 2 genders
Census 2001 and 2006, Ages 25-64
• Population sizes
• Disabled % (“often or sometimes”)
• Low income
• Adverse housing for lower income and higher income
Deaths per 1000 ages 25-64, City of Toronto combined 2000-05
(ethnic differences estimated, not available)
CCHS combined 2001-08 (4 cycles), Ages 25-64
• Chronically illness
• Healthcare access
• Unhealthy behaviour
• Social cohesion
185/28/2013 | www.wellesleyinstitute.com
Dynamic Hypothesis
19
The figure maps causal pathways in the model. The variables in red are the intervention options. The orange arrows indicate
stabilizing effects, and blue arrows indicate reinforcing effects.
Low income %
Unhealthy
behaviour %
Poor access to
primary care %
Disabled %
Chronically ill %
Death rate
Social
cohesion %
Adverse
housing %
Employment/income
interventions
Health care
interventions
Behavioural
interventions
Social cohesion
interventions
Housing
interventions
5/28/2013 | www.wellesleyinstitute.com
Feedback loops in the model
20
- Blue arrows have reinforcing (+) effects
- Red arrows have stabilizing (-) effects
- Large + signs depict positive feedback loop
% Low-income
Prevalence of
disability
Prevalence of
chronic illness
Prevalence of
unhealthy behaviour
& obesity
Poor health care
access %
Adverse
housing
Social cohesion
interventions
+
Health care access
interventions
Unhealthy
behaviour
interventions
Housing
interventions
Social cohesion
-
-Employment/income
interventions
-
-
-
-
5/28/2013 | www.wellesleyinstitute.com
Hypothesis Testing
• Multivariate regression analysis was conducted to
test causal connections and to produce effect
estimates to parameterize the simulation model
• Conducting analysis at the subgroup level (not
individual)
• treat each subgroup as a single observation
• Controlling for demographic variables
215/28/2013 | www.wellesleyinstitute.com
Limitations
• Other important SDoH not included
• Interventions are aggregate
• Community support and care not captured
• Lack of historical data to do trend analysis
• Measurement issues associated with certain variables
• Lack of projections for poverty and housing
225/28/2013 | www.wellesleyinstitute.com
Model Uses
1. planning, strategizing and advocating for improving
population health outcomes
2. a learning tool to ground policy development & analysis
for dynamically interacting and complex SDoH
• Introduce systems thinking
3. allows decision-makers to ask "what if" questions and
test different courses of action
4. building a shared understanding and consensus among
diverse groups with differing views on issues
5. eliciting stakeholder views and knowledge
6. strengthening community dialogue
235/28/2013 | www.wellesleyinstitute.com
How do interventions work?
• There are 5 intervention options to choose from
• Interventions are ramped up over the period
2011-15 and stay in force through 2046
• Range from 0 to 100%
• Broad-based
• For example:
• implementing 30% of the behavioural intervention
reduces unhealthy behaviour by 30% in all
population segments
245/28/2013 | www.wellesleyinstitute.com
Interface & Scenario Demonstration
255/28/2013 | www.wellesleyinstitute.com
Discussion Questions
• How could you imagine using the model?
• Who would you use the model with?
• What would need to be developed to facilitate
that use?
265/28/2013 | www.wellesleyinstitute.com
For more information
Mahamoud A. Roche B, Homer J. Modeling the
Social Determinants of Health and Simulating
Short-Term and Long-Term Intervention
Impacts for the City of Toronto, Canada. Soc
Sci Med (in press).
275/28/2013 | www.wellesleyinstitute.com
© The Wellesley Institute
www.wellesleyinstitute.com
Acknowledgement
Collaborators
1. Jack Homer, Homer Consulting
Modeling
2. Dianne Patychuck, Steps to
Equity
Data collection
3. Carey Levinton, Equity Magic
Structural equation modeling
Advisors
1. Nathaniel Osgood, University of
Saskatchewan
2. Peter Hovmand, Washington
University
3. Bobby Milstein, US CDC
285/28/2013 | www.wellesleyinstitute.com
THANK YOU
Please visit us at
www.wellesleyinstitute.com
5/28/2013 | www.wellesleyinstitute.com

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Modeling the Determinants of Health in Complex Policy Environments: A System Dynamics Perspective

  • 1. Modeling the Determinants of Health in Complex Policy Environments: A System Dynamics Perspective Aziza Mahamoud Bob Gardner February 14, 2013 Centre for Research on Inner City Health 1
  • 2. Objective • Background • Introduction to simulation models and system dynamics • Overview of urban health model and user interface • Hands-on experience with using the urban health model and interface • Discussion 22/14/2014 | www.wellesleyinstitute.com
  • 3. The Problem to Solve: Systemic Health Inequities in Ontario •there is a clear gradient in health in which people with lower income, education or other indicators of social inequality and exclusion tend to have poorer health •+ major differences between women and men •the gap between the health of the best off and most disadvantaged can be huge – and damaging •impact and severity of these inequities can be concentrated in particular populations and neighbourhoods 35/28/2013 | www.wellesleyinstitute.com
  • 4. these health inequities are based in structured social and economic inequality – social determinants of health • income inequality and poverty • inequitable access to childcare and early development resources • precarious employment, unsafe work • racism, social exclusion • inadequate and unaffordable housing • decaying social safety nets 45/28/2013 | www.wellesleyinstitute.com
  • 5. Canadians With Chronic Conditions Who Also Report Food Insecurity 5
  • 6. We live in a world that is increasingly more complex, dynamic & interconnected 6 Better tools are needed to help us understand and manage complexity! 5/28/2013 | www.wellesleyinstitute.com
  • 7. Health Inequities = ‘Wicked’ Problems • this means they are: • shaped by many inter-related and inter-dependent factors • in constantly changing social, economic, community and policy environments • action has to be taken at multiple levels -- by many levels of government, service providers, other stakeholders and communities • solutions are not always clear and policy agreement can be difficult to achieve • effects take years to show up • have to be able to understand and navigate this complexity to develop solutions • we need to be able to: • identify the connections between multiple factors → the key pathways to change → the mechanisms or levers that drive change along these pathways • specify the outcomes expected and the preconditions for achieving them • understand how to deploy these levers in specific social, institutional and policy contexts 75/28/2013 | www.wellesleyinstitute.com
  • 8. Systems Approach at Wellesley Institute WI has been working with stakeholders to explore the use of systems thinking and modeling to • inform our understanding of the complexities of the social determinants of health • identify, assess and develop effective policy alternatives to advance health equity • consider how new approaches like this can be informed by and connected to community perspectives and policy needs 85/28/2013 | www.wellesleyinstitute.com
  • 9. 9 “All models are wrong, but some are useful” 5/28/2013 | www.wellesleyinstitute.com George E. P. Box Robustness in the Strategy of Scientific Model Building, 1979
  • 10. Why Develop Simulation Models? • Systems are complex • Help us be explicit about our mental models • Theory building and testing • A virtual world to design and assess intervention strategies • Tool for stakeholder engagement • Identify gaps in our knowledge of how a system works 105/28/2013 | www.wellesleyinstitute.com
  • 11. Systems Dynamics: What is it? • Field developed by Jay. W. Forrester at MIT in the 1950s • “The use of informal maps and formal models with computer simulation to uncover and understand endogenous sources of system behavior” (Richardson, 2011) Richardson, G.P. (2011). Reflections on the foundations of system dynamics. System Dynamics Review, 27(3), 219-243. 115/28/2013 | www.wellesleyinstitute.com
  • 12. System Dynamics Foundations • Complexity science • Focus on the whole rather than individual parts • Interdependency • Emergent behaviour • Stock and flow • Emphasis on feedback and non-linear thinking approach to solving problems • Provides tools and techniques that can help us: • Study a system from various perspectives • Look for emerging patterns and trends over time • Examine causes of policy failures and unintended consequences • Identify effective ways of intervening (leverage points) 125/28/2013 | www.wellesleyinstitute.com
  • 13. Problem Definition Identifying Problem Causes Focus on Policy Levers Model formulation, testi ng & evaluation Knowledge Translation Applying the System Dynamics Perspective Mental Model 135/28/2013 | www.wellesleyinstitute.com
  • 14. Wellesley Urban Health Model • a computer-based systems dynamics simulation model • helps us learn and understand the complex, and dynamic interconnections between a select number of health & social factors • allows us to test what impact our decisions (interventions) will likely have on population health outcomes under various assumptions • offers insight into how these effects could play out, and over what timeframes 145/28/2013 | www.wellesleyinstitute.com
  • 15. Model Framework Population health outcomes Death rate Disability Chronic illness Social determinants of health interventions Social cohesion Health care access Affordable housing Income/jobs Behavioural Changing health & social conditions Adverse Housing Low Income Social cohesion unhealthy behaviour Poor health care access Disability Chronic illness death 155/28/2013 | www.wellesleyinstitute.com
  • 16. Model Scope Population: City of Toronto Distinguishes people by: • Ethnicity (Black, White, E Asian, SW Asian, Other) • Immigrant status (Recent, Established, Native-born) • Gender Captures: • 5 areas of intervention: Healthcare access, Health behavior, Income, Housing (lower & non-lower income), Social cohesion • Outcomes: Changes in overall deaths and health conditions, and disparity ratios Timeframe: 2006 – 2046 Age: 25-64 165/28/2013 | www.wellesleyinstitute.com
  • 17. Outcome measures & definitions Unhealthy behaviour & obese: the prevalence of people who are smokers or obese (POWER 2009). Chronic illness: having two or more of 12 chronic conditions as specified by the Association of Public Health Epidemiologists in Ontario (POWER 2009) Access to health care: the ease of getting an appointment for primary care Disability: limitation in activities of daily living Mortality: age-standardized death rate Adverse housing: overcrowding (insufficient bedrooms) Social cohesion: feeling “strong sense of community belonging " 175/28/2013 | www.wellesleyinstitute.com
  • 18. Data Sources and Parameter Estimation All data or estimates broken out by 30 subgroups: 5 ethnicities x 3 immigrant statuses x 2 genders Census 2001 and 2006, Ages 25-64 • Population sizes • Disabled % (“often or sometimes”) • Low income • Adverse housing for lower income and higher income Deaths per 1000 ages 25-64, City of Toronto combined 2000-05 (ethnic differences estimated, not available) CCHS combined 2001-08 (4 cycles), Ages 25-64 • Chronically illness • Healthcare access • Unhealthy behaviour • Social cohesion 185/28/2013 | www.wellesleyinstitute.com
  • 19. Dynamic Hypothesis 19 The figure maps causal pathways in the model. The variables in red are the intervention options. The orange arrows indicate stabilizing effects, and blue arrows indicate reinforcing effects. Low income % Unhealthy behaviour % Poor access to primary care % Disabled % Chronically ill % Death rate Social cohesion % Adverse housing % Employment/income interventions Health care interventions Behavioural interventions Social cohesion interventions Housing interventions 5/28/2013 | www.wellesleyinstitute.com
  • 20. Feedback loops in the model 20 - Blue arrows have reinforcing (+) effects - Red arrows have stabilizing (-) effects - Large + signs depict positive feedback loop % Low-income Prevalence of disability Prevalence of chronic illness Prevalence of unhealthy behaviour & obesity Poor health care access % Adverse housing Social cohesion interventions + Health care access interventions Unhealthy behaviour interventions Housing interventions Social cohesion - -Employment/income interventions - - - - 5/28/2013 | www.wellesleyinstitute.com
  • 21. Hypothesis Testing • Multivariate regression analysis was conducted to test causal connections and to produce effect estimates to parameterize the simulation model • Conducting analysis at the subgroup level (not individual) • treat each subgroup as a single observation • Controlling for demographic variables 215/28/2013 | www.wellesleyinstitute.com
  • 22. Limitations • Other important SDoH not included • Interventions are aggregate • Community support and care not captured • Lack of historical data to do trend analysis • Measurement issues associated with certain variables • Lack of projections for poverty and housing 225/28/2013 | www.wellesleyinstitute.com
  • 23. Model Uses 1. planning, strategizing and advocating for improving population health outcomes 2. a learning tool to ground policy development & analysis for dynamically interacting and complex SDoH • Introduce systems thinking 3. allows decision-makers to ask "what if" questions and test different courses of action 4. building a shared understanding and consensus among diverse groups with differing views on issues 5. eliciting stakeholder views and knowledge 6. strengthening community dialogue 235/28/2013 | www.wellesleyinstitute.com
  • 24. How do interventions work? • There are 5 intervention options to choose from • Interventions are ramped up over the period 2011-15 and stay in force through 2046 • Range from 0 to 100% • Broad-based • For example: • implementing 30% of the behavioural intervention reduces unhealthy behaviour by 30% in all population segments 245/28/2013 | www.wellesleyinstitute.com
  • 25. Interface & Scenario Demonstration 255/28/2013 | www.wellesleyinstitute.com
  • 26. Discussion Questions • How could you imagine using the model? • Who would you use the model with? • What would need to be developed to facilitate that use? 265/28/2013 | www.wellesleyinstitute.com
  • 27. For more information Mahamoud A. Roche B, Homer J. Modeling the Social Determinants of Health and Simulating Short-Term and Long-Term Intervention Impacts for the City of Toronto, Canada. Soc Sci Med (in press). 275/28/2013 | www.wellesleyinstitute.com
  • 28. © The Wellesley Institute www.wellesleyinstitute.com Acknowledgement Collaborators 1. Jack Homer, Homer Consulting Modeling 2. Dianne Patychuck, Steps to Equity Data collection 3. Carey Levinton, Equity Magic Structural equation modeling Advisors 1. Nathaniel Osgood, University of Saskatchewan 2. Peter Hovmand, Washington University 3. Bobby Milstein, US CDC 285/28/2013 | www.wellesleyinstitute.com
  • 29. THANK YOU Please visit us at www.wellesleyinstitute.com 5/28/2013 | www.wellesleyinstitute.com

Notas del editor

  1. POWER data age-standardized % of adults 2005overall patterns – 3 X as many low income as high report health to be only fair or poor self-reported = good proxy for clinical outcomes but exactly the point here, capturing people’s experience of their health
  2. In: SDoH lead to gradient of health in chronic conditionsplus affect how people can deal with the conditionsOut: complex and reinforcing nature of social determinants on health disparities
  3. A way of forcing us to think about the interconnections, to demonstrate in our work, the SDOH we`ve chosen reflects where put the emphasisThe social determinants of health are inter-connected, interdependent and dynamicMultiple levels of determinants and pathwaysDisplay cumulative and reinforcing effects over timeIntergenerational influences and accumulation of social disadvantage
  4. a famous quote by a statistician George E. P. BoxAll models are essentially simplification of reality, but some can make better depictions than others
  5. Systems are compelx and we cannot afford to use simplistic models that assume linear connections
  6. A problem solving methodology
  7. dynamic complexities – co behaviour of system as a results of interactions of agents over timeCounterintuitive behaviour – unintended consequence, as a results of the distal feedback effects of our decisions and policies that we do not anticipateLeverage points – finding where in the system should we interveneThe focus is on system structure, rather than events and patterns – with emphasis on questions such as what’s causing the events we are seeing and why are patters occurring
  8. It’s a reiterative process, a co-evolution process whereby our mental models are the centre, both tranforming the process of modeling as well as being transformed by it as we become explicit about our assumptionsOften, the greatest value is gained through the modeling process as opposed to the models built, the end result....this is sometimes not so obvious as stakeholders may put all the emphasis on the outcome of the simluation
  9. For cchs variable, for some there was only 2001 data, and others, both data years
  10. This is our dynamic hypothesis, or the hypothesized system structure with causal pathways and how interventions are affecting them.The model
  11. 4 feedback loops and two delays – key concepts in system structureAll operating through income, and most through disability and some through chronic illness
  12. We are testing our theory, or hypothesized causal relationships in the initial model to see if these are supported by our data, and how significant, strong, or weak the relationships are, and then we refine the dynamic hypothesis in a reiterative fashionLinear regression – some of the variables had two metrics, and both were tested
  13. We are assuming interventions operate exogenously, i.e. they are unidirectional, which means we are not capturing any feedback effects from the changing health conditions and determinants on the interventions themselvesMany of the challenges due lack of trend data - inability to reproduce the historical epidemiologic profile
  14. To remind people, that we now will be talking about simulation model results under different assumtions, and how structure we have discussed derives behaviour, we are looking at model results given assumptionsOur hypothesised causal relationships that underlie the bevaviour – structure determines determinesbevaviour