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VOLUME 1, ISSUE 4             11/12/12




 HORMONES, THE PERFECT STORM?
 NORTHWEST ISD




Written by—Agron Mena
                       Hormone                   tion in the digestive tract
                       Glucagon= Pancreatic      Gonads= primary sex organs in the male and
                       islets= Promotes          in the female. Each is structured differently,
                       movements of glucose      and each produces its own unique set of hor-
                       from storage and into     mones
                       the blood
                                                 Testes= Are paired organs within a sac of
                       Insulin= Pancreatic       skin called scrotum, what produces male sex
                       islets= Promotes          hormones
                       movements of glucose
                                                 Ovaries= are a set of paired glands in the
                       out of the blood into
                                                 pelvis that creates several types of hormone
                       the cells
                                                 including estrogens, and progesterone, what
                       Somatostatin= Pancre-     produces women’s sex hormones
© (17)                 atic islets= can have
                       general effects in the
                                                 Steroid hormones= usually used for sports
                                                 build up large molecules (anabolism)will
                       body, but primary
                                                 cause negative feed back such as atrophy of
                       role seems to be reg-
                                                 the testes.
                       ulation of secretion of
                       the pancreatic hor-
                       mones
                       Pancreatic polypep-
                       tide = pancreatic is-
                       lets= excact functions
                       incertain, but seems
                       to influence absorp-




                                   Inside this issue:

             Agron Mena                                                        1

             Colton Goudie                                                     2

             Jasmine Bountom                                                   3

             Ashley Bookston                                                   4—5

             Kamiera Taylor                                                    6
HORMONES, THE PERFECT STORM?
Page 2




           Written by—Colton Goudie




                                                    16-6
                           The target cell concept. A hormone acts only on cells
                           that have receptors specific to that hormone because
                                                     the shape of the receptor de-
                                                     termines which hormone can
                                                     react with it. This is an exam-
                                                     ple of the lock-and-key model
                                                     of biochemical reaction. (1)
VOLUME 1, ISSUE 4
                                                                Page 3




Written By—Jasmine Bountom
The endocrine      glands like thy-   stream to control many func-
system is re-      roid glands to     tions of the body. This system
sponsible for      secrete thyroid    overlaps with the nervous sys-
the regulation     hormones           tem and exocrine system, and
of hormones in     The endocrine      its responsibilities include
the body. It       system is a col-   metabolism, growth and sexu-
works with         lection of         al development Many of the
nervous system     glands and or-     basic hormones are active
by stimulating     gans that pro-     from birth, but most of the
the brain to re-   duce and regu-     hormones relates to repro-
lease hormone      late hormones      ductive functions are not pro-
to stimulate       in the blood-      duced or secreted
                                      until puberty.




                                           © (18)
NEWSLETTER TITLE
Page 4
                             Written By- Ashley Bookston
 Hormone                      Source                      Target                       Principle Action
 Growth hormone-              Hypothalamus                Adenohypophysis              Stimulates secretion of
 releasing hormone                                        (somatotrophs)               growth hormone
 Growth hormone-              Hypothalamus                Adenohypophysis              Inhibits secretion of
 inhibiting hormone (GIH)                                 (somatotrophs)               growth hormone
 ir somatostatin

 Corticotropin-releasing      Hypothalamus                Adenohypophysis              Stimulates release of
 hormone (CRH)                                            (corticotrophs)              adrenocorticotropic hor-
                                                                                       mone (ACTH)

 Thryotropin-releasing        Hypothalamus                Adenohypophysis              Stimulates release of thy-
 hormone (TRH)                                            (thyrotrophs)                roid-stimulating hormone
                                                                                       (TSH)

 Gonadotropin-releasing       Hypothalamus                Adenohypophysis              Stimulates release of gon-
 hormone (GNRH)                                           (gonadotrophs)               adotropins (FSH and LH)


 Prolactin-releasing hor-     Hypothalamus                Adenohypophysis              Stimulates secretion of
 mone (PRH)                                               (corticotrophs)              prolactin
 Prolaction-inhibiting hor-   Hypothalamus                Adenohypophysis              Inhibits secretion of pro-
 mone (PIH)                                               (corticotrophs)              lactin

 Growth hormone (GH)          Adenohypophysis             General                      Promotes growth by stim-
 (somatotropin [STH])         (somatotrophs)                                           ulating protein anabolism
                                                                                       and fat mobilization
 Prolactin (PRL)              Adenohypophysis             Mammary glands               Promotes milk secretion
 (lactogenic hormone)         (lactotrophs)               (alveolar secretory cells)
 Thyroid-stimulating hor-     Adenohypophysis             Thyroid glands               Stimulates development
 mone (TSH)*                  (thyrotrophs)                                            and secretion in the thy-
                                                                                       roid gland
 Adrenocorticotropic hor-     Adenohypophysis             Adrenal cortex               Promotes development
 mone (ACTH)*                 (corticotrophs)                                          and secretion in the ad-
                                                                                       renal cortex
 Follicle-stimulating hor-    Adenohypophysis             Gonads (primary sex or-      Female- promotes devel-
 mone (FSH)*                  (gonadotrophs)              gans)                        opments of ovarian folli-
                                                                                       cle; stimulates estrogen
                                                                                       secretion
                                                                                       Male- promotes develop-
                                                                                       ment of testis; stimulates
                                                                                       sperm production
 Luteinizing hormone (LH)     Adenohypophysis             Gonads                       Female- triggers ovula-
 *                            (gonadotrophs)                                           tion; promotes develop-
                                                                                       ment of corpus luteum
                                                                                       Male- stimulates produc-
                                                                                       tion of testosterone
 Antidiuretic hormone         Neurohypophysis             Kidney                       Promotes water retention
 (ADH)                                                                                 by kidney tubules
 Oxytocin (OT)                Neurohypophysis             Uterus and mammary           Stimulates uterine con-
                                                          glands                       tractions; stimulates ejec-
                                                                                       tion of milk into mamma-
                                                                                       ry ducts
 Triiodothyronine (T3)        Thyroid gland (follicular   General                      Increase rate of metabo-
                              cells)                                                   lism
 Tetraiodothyronine (T4)      Thyroid gland (follicular   General                      Increase rate of metabo-
 or thyroxine                 cells)                                                   lism (usually converted to
                                                                                       T3 first)
 Calcitonin (CT)              Thyroid gland               Bone tissue                  Increases calcium stor-
                              (parafollicular cells)                                   age in bone, lowering
                                                                                       blood calcium levels
VOLUME 1, ISSUE 1
                                                                                                          Page 5
Parathyroid hormone         Parathyroid glands           Bone tissue and kidney       Increases calcium remov-
(PTH) or parathormone                                                                 al from storage in bone
                                                                                      and produces the active
                                                                                      form of vitamin D in the
                                                                                      kidneys, increasing ab-
                                                                                      sorption of calcium by
                                                                                      intestines and increasing
                                                                                      blood calcium levels
Aldosterone                 Adrenal cortex (zona glo-    Kidney                       Stimulates kidney tubules
                            merulosa)                                                 to conserve sodium,
                                                                                      which, in turn, triggers
                                                                                      the release of ADH and
                                                                                      the resulting conserva-
                                                                                      tion of water by the kid-
                                                                                      ney
Cortisol (hydrocortisone)   Adrenal cortex (zona fas-    General                      Influences metabolism of
                            ciculata)                                                 food molecules; in large
                                                                                      amounts, it has an anti-
                                                                                      inflammatory effect
Adrenal androgens           Adrenal cortex (zona re-     Sex organs, other effec-     Exact role uncertain, but
                            ticularis)                   tors                         may support sexual func-
                                                                                      tion
Adrenal estrogens           Adrenal cortex (zona re-     Sex organs                   Thought to be physiologi-
                            ticularis)                                                cally insignificant
Epinephrine (adrenaline)    Adrenal medulla              Sympathetic effectors        Enhances and prolongs
                                                                                      the effects of the sympa-
                                                                                      thetic division of the auto-
                                                                                      nomic nervous system

Norepinephrine              Adrenal medulla              Sympathetic effectors        Enhances and prolongs
                                                                                      the effects of the sympa-
                                                                                      thetic division of the auto-
                                                                                      nomic nervous system
Glucagon                    Pancreatic islets (alpha a   General                      Promotes movement of
                            cells or A cells)                                         glucose from storage and
                                                                                      into the blood
Insulin                     Pancreatic islets (beta b    Pancreatic cells and other   Can have general effects
                            cells or B cells)            effectors                    in the body, but primary
                                                                                      role seems to be regula-
                                                                                      tion of secretion of other
                                                                                      pancreatic hormones
Somatosatin                 Pancreatic islets (delta d   Pancreatic cells and other   Can have general effects
                            cells or D cells)            effectors                    in the body, but primary
                                                                                      role seems to be regula-
                                                                                      tion of secretion of other
                                                                                      pancreatic hormones
Pancreatic polypeptide      Pancreatic islets            Intestinal cells and other   Exact function uncertain,
                            (pancreatic polyperptide     effectors                    but seems to influence
                            [PP] or F cells                                           absorption in the diges-
                                                                                      tive tract
NORTHWEST ISD




Written By—Kamiera Taylor


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Artifact 4

  • 1. VOLUME 1, ISSUE 4 11/12/12 HORMONES, THE PERFECT STORM? NORTHWEST ISD Written by—Agron Mena Hormone tion in the digestive tract Glucagon= Pancreatic Gonads= primary sex organs in the male and islets= Promotes in the female. Each is structured differently, movements of glucose and each produces its own unique set of hor- from storage and into mones the blood Testes= Are paired organs within a sac of Insulin= Pancreatic skin called scrotum, what produces male sex islets= Promotes hormones movements of glucose Ovaries= are a set of paired glands in the out of the blood into pelvis that creates several types of hormone the cells including estrogens, and progesterone, what Somatostatin= Pancre- produces women’s sex hormones © (17) atic islets= can have general effects in the Steroid hormones= usually used for sports build up large molecules (anabolism)will body, but primary cause negative feed back such as atrophy of role seems to be reg- the testes. ulation of secretion of the pancreatic hor- mones Pancreatic polypep- tide = pancreatic is- lets= excact functions incertain, but seems to influence absorp- Inside this issue: Agron Mena 1 Colton Goudie 2 Jasmine Bountom 3 Ashley Bookston 4—5 Kamiera Taylor 6
  • 2. HORMONES, THE PERFECT STORM? Page 2 Written by—Colton Goudie 16-6 The target cell concept. A hormone acts only on cells that have receptors specific to that hormone because the shape of the receptor de- termines which hormone can react with it. This is an exam- ple of the lock-and-key model of biochemical reaction. (1)
  • 3. VOLUME 1, ISSUE 4 Page 3 Written By—Jasmine Bountom The endocrine glands like thy- stream to control many func- system is re- roid glands to tions of the body. This system sponsible for secrete thyroid overlaps with the nervous sys- the regulation hormones tem and exocrine system, and of hormones in The endocrine its responsibilities include the body. It system is a col- metabolism, growth and sexu- works with lection of al development Many of the nervous system glands and or- basic hormones are active by stimulating gans that pro- from birth, but most of the the brain to re- duce and regu- hormones relates to repro- lease hormone late hormones ductive functions are not pro- to stimulate in the blood- duced or secreted until puberty. © (18)
  • 4. NEWSLETTER TITLE Page 4 Written By- Ashley Bookston Hormone Source Target Principle Action Growth hormone- Hypothalamus Adenohypophysis Stimulates secretion of releasing hormone (somatotrophs) growth hormone Growth hormone- Hypothalamus Adenohypophysis Inhibits secretion of inhibiting hormone (GIH) (somatotrophs) growth hormone ir somatostatin Corticotropin-releasing Hypothalamus Adenohypophysis Stimulates release of hormone (CRH) (corticotrophs) adrenocorticotropic hor- mone (ACTH) Thryotropin-releasing Hypothalamus Adenohypophysis Stimulates release of thy- hormone (TRH) (thyrotrophs) roid-stimulating hormone (TSH) Gonadotropin-releasing Hypothalamus Adenohypophysis Stimulates release of gon- hormone (GNRH) (gonadotrophs) adotropins (FSH and LH) Prolactin-releasing hor- Hypothalamus Adenohypophysis Stimulates secretion of mone (PRH) (corticotrophs) prolactin Prolaction-inhibiting hor- Hypothalamus Adenohypophysis Inhibits secretion of pro- mone (PIH) (corticotrophs) lactin Growth hormone (GH) Adenohypophysis General Promotes growth by stim- (somatotropin [STH]) (somatotrophs) ulating protein anabolism and fat mobilization Prolactin (PRL) Adenohypophysis Mammary glands Promotes milk secretion (lactogenic hormone) (lactotrophs) (alveolar secretory cells) Thyroid-stimulating hor- Adenohypophysis Thyroid glands Stimulates development mone (TSH)* (thyrotrophs) and secretion in the thy- roid gland Adrenocorticotropic hor- Adenohypophysis Adrenal cortex Promotes development mone (ACTH)* (corticotrophs) and secretion in the ad- renal cortex Follicle-stimulating hor- Adenohypophysis Gonads (primary sex or- Female- promotes devel- mone (FSH)* (gonadotrophs) gans) opments of ovarian folli- cle; stimulates estrogen secretion Male- promotes develop- ment of testis; stimulates sperm production Luteinizing hormone (LH) Adenohypophysis Gonads Female- triggers ovula- * (gonadotrophs) tion; promotes develop- ment of corpus luteum Male- stimulates produc- tion of testosterone Antidiuretic hormone Neurohypophysis Kidney Promotes water retention (ADH) by kidney tubules Oxytocin (OT) Neurohypophysis Uterus and mammary Stimulates uterine con- glands tractions; stimulates ejec- tion of milk into mamma- ry ducts Triiodothyronine (T3) Thyroid gland (follicular General Increase rate of metabo- cells) lism Tetraiodothyronine (T4) Thyroid gland (follicular General Increase rate of metabo- or thyroxine cells) lism (usually converted to T3 first) Calcitonin (CT) Thyroid gland Bone tissue Increases calcium stor- (parafollicular cells) age in bone, lowering blood calcium levels
  • 5. VOLUME 1, ISSUE 1 Page 5 Parathyroid hormone Parathyroid glands Bone tissue and kidney Increases calcium remov- (PTH) or parathormone al from storage in bone and produces the active form of vitamin D in the kidneys, increasing ab- sorption of calcium by intestines and increasing blood calcium levels Aldosterone Adrenal cortex (zona glo- Kidney Stimulates kidney tubules merulosa) to conserve sodium, which, in turn, triggers the release of ADH and the resulting conserva- tion of water by the kid- ney Cortisol (hydrocortisone) Adrenal cortex (zona fas- General Influences metabolism of ciculata) food molecules; in large amounts, it has an anti- inflammatory effect Adrenal androgens Adrenal cortex (zona re- Sex organs, other effec- Exact role uncertain, but ticularis) tors may support sexual func- tion Adrenal estrogens Adrenal cortex (zona re- Sex organs Thought to be physiologi- ticularis) cally insignificant Epinephrine (adrenaline) Adrenal medulla Sympathetic effectors Enhances and prolongs the effects of the sympa- thetic division of the auto- nomic nervous system Norepinephrine Adrenal medulla Sympathetic effectors Enhances and prolongs the effects of the sympa- thetic division of the auto- nomic nervous system Glucagon Pancreatic islets (alpha a General Promotes movement of cells or A cells) glucose from storage and into the blood Insulin Pancreatic islets (beta b Pancreatic cells and other Can have general effects cells or B cells) effectors in the body, but primary role seems to be regula- tion of secretion of other pancreatic hormones Somatosatin Pancreatic islets (delta d Pancreatic cells and other Can have general effects cells or D cells) effectors in the body, but primary role seems to be regula- tion of secretion of other pancreatic hormones Pancreatic polypeptide Pancreatic islets Intestinal cells and other Exact function uncertain, (pancreatic polyperptide effectors but seems to influence [PP] or F cells absorption in the diges- tive tract
  • 6. NORTHWEST ISD Written By—Kamiera Taylor Never got Part...