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Inside lab07.fasta, here is the sequence:
>lab07
ttatgtactctaaggaaagaaataaacatttaaaaaaatgttgaaaaaattttaaataaaactgcatacc
aatagcctgatgagtatgtatgcCGaaattctcattaaaataccttcaaattaaagtcaacaatacatta
atagaatcatttaccataatcaagtgggatatatccctggcttcaagggtggtaccacattcacagatca
atcaacatgatgcaccacagtaatagaagaaaggataagaacaatatgatgctttcaacagatgcaggaa
aaccatttgacaaaatgtcacatccattcatgataaaaaCGctcagcaaagtacattgagactcaaccta
cctgcacataataaaagtcatctaggaaaaacccacagctaatctcatcctcaatggggaaaaattgaaa
gttgttcctccaaggtcagggacaagacagggatgacccctctcaccactgttattcacatagtaCGgga
aatcctagccacagcaatcagacaacaaaaagaaataagaggcatccaaatcagcaaggaagaagtagca
cattttctatttggaactgacatgatgtgctctataagaaacatgaaagactcccttaaaaattgctaga
attgatatatgaattCGacaagtcacaatacacagaaatcaatgtacataaatgtattgcatttctatac
aCGaatcatgaattaacagagagagaaagtaagggatcaaacccatttacaggttcacaaataccacaag
ataccaggaatatacctaaccaaagaagtcaaagacctgtactctaaaggctatgaaatgatgatgaaaa
aaatggaagaggacacaaagaaatggaaatacatttcatgttcatggatggcaagaacaaaatactgtta
aaatgtctacagtcctcaaaacaatctacacatgtaatgaaatccctatcacactaacaaaaacatttgt
cacagaaatggaacaaataatctcaaaatgtgtatggaatgacaaaagtccccaaacagccaaaacaaac
ttgaagaagaaaagcaaagctggagacatcacaatcccagactttaggttatattacaaagctgtactga
tcagaacagtatggtactggcaaaacaacaacaacaacaacaacaacacacagaggcagagatcaataga
atagaaacccagaaatgaactcacacctgtatggtcaattaattctcaacaaagcaggaaagaatatcca
atggaaaaaaaaaaaaaaagatagtcttgggacacatggatgtctcagtcaccaaagtgtgtgattgtgg
attcagctcaggtcatgatctcagggcagtgcagagcatgCGtgggattctctctctccatttctctctg
cccctcttttgcatgctctctctctctcaaaaataaacacataaacctaaaaaaaaaaacctcctcaaca
tatggttttgaaaaaactggacagcaacctgcaagacaaaacaacaaCGgaccactttcttacaacatac
acaaaaataaatccaacatggataaagacctatgtgtgaaacctgaaagcataaaaatcccagaggataa Simulate 100
sequences with the same length as lab07.fasta using your Markov model generated from
lab07.fasta. What is the mean and standard deviation of the number of occurrences of 'CpG' in
the simulated sequences. They should be very similar to the observed values, which would
indicate the model adequately simulates the observed CpG frequency.

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Simulated CpG frequency from lab07 Markov model

  • 1. Inside lab07.fasta, here is the sequence: >lab07 ttatgtactctaaggaaagaaataaacatttaaaaaaatgttgaaaaaattttaaataaaactgcatacc aatagcctgatgagtatgtatgcCGaaattctcattaaaataccttcaaattaaagtcaacaatacatta atagaatcatttaccataatcaagtgggatatatccctggcttcaagggtggtaccacattcacagatca atcaacatgatgcaccacagtaatagaagaaaggataagaacaatatgatgctttcaacagatgcaggaa aaccatttgacaaaatgtcacatccattcatgataaaaaCGctcagcaaagtacattgagactcaaccta cctgcacataataaaagtcatctaggaaaaacccacagctaatctcatcctcaatggggaaaaattgaaa gttgttcctccaaggtcagggacaagacagggatgacccctctcaccactgttattcacatagtaCGgga aatcctagccacagcaatcagacaacaaaaagaaataagaggcatccaaatcagcaaggaagaagtagca cattttctatttggaactgacatgatgtgctctataagaaacatgaaagactcccttaaaaattgctaga attgatatatgaattCGacaagtcacaatacacagaaatcaatgtacataaatgtattgcatttctatac aCGaatcatgaattaacagagagagaaagtaagggatcaaacccatttacaggttcacaaataccacaag ataccaggaatatacctaaccaaagaagtcaaagacctgtactctaaaggctatgaaatgatgatgaaaa aaatggaagaggacacaaagaaatggaaatacatttcatgttcatggatggcaagaacaaaatactgtta aaatgtctacagtcctcaaaacaatctacacatgtaatgaaatccctatcacactaacaaaaacatttgt cacagaaatggaacaaataatctcaaaatgtgtatggaatgacaaaagtccccaaacagccaaaacaaac ttgaagaagaaaagcaaagctggagacatcacaatcccagactttaggttatattacaaagctgtactga tcagaacagtatggtactggcaaaacaacaacaacaacaacaacaacacacagaggcagagatcaataga atagaaacccagaaatgaactcacacctgtatggtcaattaattctcaacaaagcaggaaagaatatcca atggaaaaaaaaaaaaaaagatagtcttgggacacatggatgtctcagtcaccaaagtgtgtgattgtgg attcagctcaggtcatgatctcagggcagtgcagagcatgCGtgggattctctctctccatttctctctg cccctcttttgcatgctctctctctctcaaaaataaacacataaacctaaaaaaaaaaacctcctcaaca tatggttttgaaaaaactggacagcaacctgcaagacaaaacaacaaCGgaccactttcttacaacatac acaaaaataaatccaacatggataaagacctatgtgtgaaacctgaaagcataaaaatcccagaggataa Simulate 100 sequences with the same length as lab07.fasta using your Markov model generated from lab07.fasta. What is the mean and standard deviation of the number of occurrences of 'CpG' in the simulated sequences. They should be very similar to the observed values, which would indicate the model adequately simulates the observed CpG frequency.