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Pulmonary-Renal Syndrome Alanna Beckman MSIV
Pulmonary-Renal Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diffuse Alveolar Hemorrhage ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Capillaritis: neutrophile infiltrates and hemorrhage
Rapidly Progressive Glomerulonephritis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pulmonary-Renal Syndromes ,[object Object],[object Object],[object Object]
 
Work-up for GN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Goodpastures ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Goodpasture’s Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
GP Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Normal Glomerulus RPGN/Crescentic GN ,[object Object],[object Object]
GP Treatment ,[object Object],[object Object]
GP Prognosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ANCA Vasculitis (pauci-immune) ,[object Object],[object Object],[object Object]
ANCA + Vasculitis (pauci-immune) PR3 = Proteinase 3 MPO = Myeloperoxidase (found in granules of neutrophils/monocytes) 50% P-ANCA (anti-MPO) + 70% 45% + Churg-Strauss Syndrome 70% P-ANCA (anti-MPO) - 50% 90% - Microscopic polyantiitis 90% C-ANCA (anti-PR3) - 90% 80% + Wegener’s granulo-matosis ANCA positive ANCA type Asthma Pulmonary Renal Granulomas Disease
ANCA-associated small vessel vasculitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ANCA-associated small vessel vasculitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
C-ANCA  PR3
Wegener’s ,[object Object],[object Object],[object Object]
Wegener’s ,[object Object],[object Object],[object Object],[object Object],[object Object]
Wegener’s ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Wegener’s ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Wegener’s ,[object Object],[object Object],[object Object],[object Object],[object Object]
Wegener’s ,[object Object],[object Object],[object Object],[object Object]
Wegener’s ,[object Object],[object Object],[object Object],[object Object]
P-ANCA  MPO
Churg-Strauss ,[object Object],[object Object],[object Object],[object Object],[object Object]
Churg-Strauss ,[object Object],[object Object],[object Object],[object Object]
Churg-Strauss ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Churg-Strauss ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Churg-Strauss ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Churg-Strauss ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Churg-Strauss ,[object Object],[object Object],[object Object],[object Object]
P-ANCA  MPO
Microscopic Polyangiitis. ,[object Object],[object Object],[object Object],[object Object]
Microscopic Polyangiitis ,[object Object],[object Object],[object Object]
Microscopic Polyangiitis ,[object Object],[object Object],[object Object],[object Object]
Microscopic Polyangiitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Microscopic Polyangiitis ,[object Object],[object Object],[object Object],[object Object]
Microscopic Polyangiitis ,[object Object],[object Object],[object Object]
 
Differential Diagnosis for Pulmonary-Renal Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Pleural effusions/Lupus Pneumonitis + SLE GN + ASO titer, can continue to have pulmonary symptoms by the time renal symptoms manifest.
 
references ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Coverted PPT

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  • 15. ANCA + Vasculitis (pauci-immune) PR3 = Proteinase 3 MPO = Myeloperoxidase (found in granules of neutrophils/monocytes) 50% P-ANCA (anti-MPO) + 70% 45% + Churg-Strauss Syndrome 70% P-ANCA (anti-MPO) - 50% 90% - Microscopic polyantiitis 90% C-ANCA (anti-PR3) - 90% 80% + Wegener’s granulo-matosis ANCA positive ANCA type Asthma Pulmonary Renal Granulomas Disease
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  • 18. C-ANCA  PR3
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  • 26. P-ANCA  MPO
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  • 34. P-ANCA  MPO
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