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Which organelle is responsible for: 
1. Degrading worn-out organelles 
2. Synthesis of lipids and steroid molecules 
3. Packaging proteins for export, modifying proteins 
for membranes, packing enzymes into lysosomes 
4. Modifying proteins 
5. Containing enzymes that convert toxic 
substances to hydrogen peroxide, then water 
6. Making proteins 
7. Cellular respiration 
8. Movement of cell parts, cell motility,
Part 3: Cytoplasm & Nucleus
 Between plasma membrane & nucleus 
 Three elements: 
CCyyttoossooll: fluid 
 Eg. water, proteins, salts, sugars 
OOrrggaanneelllleess: specific functions 
IInncclluussiioonnss: chemical substances that vary 
depending on cell type 
 Eg. glycogen (liver), lipid droplets (fat 
cells), melanin (skin & hair)
 “little organs” 
 Specialized compartments  specific 
functions 
 Membranous = membrane-bound 
Mitochondria, peroxisomes, lysosomes, ER, 
Golgi apparatus 
 Nonmembranous = no membrane 
cytoskeleton, centrioles, ribosomes
 System of organelles that work to 
1. Produce, store, export biological molecules 
2. Degrade harmful substances 
 Nuclear envelope, rough ER, smooth ER, Golgi 
apparatus, secretory vesicles, lysosomes
 Control center  contains DNA 
 Most cells have only 1 nucleus 
Multinucleate: many nuclei (muscle, some liver cells) 
Anucleate: no nucleus (mature RBC) 
 Three main structures: 
1.Nuclear envelope 
2.Nucleoli 
3.Chromatin
Multinucleated Muscle Cells 
Multinucleated Liver Cells 
Anucleated Red Blood 
Cells
 Double membrane barrier surrounds nucleus 
Outer part continuous with Rough ER 
 Nuclear pores: control entry/exit of molecules
 Dark-staining bodies in nucleus 
 1-2 per cell 
 Site where ribosomes are made
 CChhrroommaattiinn = DNA + Proteins 
 Nucleosome = DNA wrapped around 8 histone proteins 
 Histones allow for compact and orderly packing of 
long DNA molecules
During cell division, chromatin condenses to 
form chromosomes.
 Make identical copies of DNA before a cell 
divides
 Part of cell division 
 Replicated DNA divided into 2 daughter cells 
 Usually lasts about an hour 
 Interphase  prophase  metaphase  
anaphase  telophase & cytokinesis
Gene: segment of DNA that codes for 1 
polypeptide 
Exon: part of DNA that codes for polypeptides 
Intron: part of DNA that is noncoding (not 
“junk”!)
 Transcription: RNA formed from DNA 
Occurs in nucleus 
Types: mRNA, tRNA, rRNA 
 Translation: protein synthesis 
polypeptide formed from mRNA 
Occurs in cytoplasm 
By ribosomes
 Any substances outside cells 
1. Body fluids (blood plasma, interstitial fluid) 
2. Cellular secretions (saliva, mucus, gastric 
fluids) 
3. Extracellular matrix (ECM): “glue” that holds 
cells together; jelly-like substance made of 
proteins (like collagen) and carbs

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Anatomy & Physiology Lecture Notes - Ch. 3 cells - part 3

  • 1. Which organelle is responsible for: 1. Degrading worn-out organelles 2. Synthesis of lipids and steroid molecules 3. Packaging proteins for export, modifying proteins for membranes, packing enzymes into lysosomes 4. Modifying proteins 5. Containing enzymes that convert toxic substances to hydrogen peroxide, then water 6. Making proteins 7. Cellular respiration 8. Movement of cell parts, cell motility,
  • 2. Part 3: Cytoplasm & Nucleus
  • 3.
  • 4.  Between plasma membrane & nucleus  Three elements: CCyyttoossooll: fluid  Eg. water, proteins, salts, sugars OOrrggaanneelllleess: specific functions IInncclluussiioonnss: chemical substances that vary depending on cell type  Eg. glycogen (liver), lipid droplets (fat cells), melanin (skin & hair)
  • 5.  “little organs”  Specialized compartments  specific functions  Membranous = membrane-bound Mitochondria, peroxisomes, lysosomes, ER, Golgi apparatus  Nonmembranous = no membrane cytoskeleton, centrioles, ribosomes
  • 6.
  • 7.  System of organelles that work to 1. Produce, store, export biological molecules 2. Degrade harmful substances  Nuclear envelope, rough ER, smooth ER, Golgi apparatus, secretory vesicles, lysosomes
  • 8.
  • 9.
  • 10.  Control center  contains DNA  Most cells have only 1 nucleus Multinucleate: many nuclei (muscle, some liver cells) Anucleate: no nucleus (mature RBC)  Three main structures: 1.Nuclear envelope 2.Nucleoli 3.Chromatin
  • 11. Multinucleated Muscle Cells Multinucleated Liver Cells Anucleated Red Blood Cells
  • 12.  Double membrane barrier surrounds nucleus Outer part continuous with Rough ER  Nuclear pores: control entry/exit of molecules
  • 13.  Dark-staining bodies in nucleus  1-2 per cell  Site where ribosomes are made
  • 14.  CChhrroommaattiinn = DNA + Proteins  Nucleosome = DNA wrapped around 8 histone proteins  Histones allow for compact and orderly packing of long DNA molecules
  • 15.
  • 16. During cell division, chromatin condenses to form chromosomes.
  • 17.  Make identical copies of DNA before a cell divides
  • 18.  Part of cell division  Replicated DNA divided into 2 daughter cells  Usually lasts about an hour  Interphase  prophase  metaphase  anaphase  telophase & cytokinesis
  • 19. Gene: segment of DNA that codes for 1 polypeptide Exon: part of DNA that codes for polypeptides Intron: part of DNA that is noncoding (not “junk”!)
  • 20.
  • 21.  Transcription: RNA formed from DNA Occurs in nucleus Types: mRNA, tRNA, rRNA  Translation: protein synthesis polypeptide formed from mRNA Occurs in cytoplasm By ribosomes
  • 22.
  • 23.  Any substances outside cells 1. Body fluids (blood plasma, interstitial fluid) 2. Cellular secretions (saliva, mucus, gastric fluids) 3. Extracellular matrix (ECM): “glue” that holds cells together; jelly-like substance made of proteins (like collagen) and carbs