IBM Aspera In Life Sciences

© 2014 IBM Corporation
IBM Asperain Life SciencesMoments matter.

Agenda
Disruption for the Life Sciences Industry
Why IBM Asperais the Right Response to Industry Change
Executive Life Sciences Agendas for IBM Aspera
Why IBM is the Right Choice for Life Sciences
2

petabytes (1015bytes) of data being currently stored at the European Bioinformatics Institute in the UK; the genomic data doubling in size each year.1
DISRUPTOR: Big data and the cloud explosion has arrived for Life Sciences executives
“Asperais the industry standard for the
transport and management of large
data files produced by life sciences.”
SifeiHeCloud Product Director, BGI
genomes per week being generated today at $1000 each. The first human genome mapped in 2002 took 20 institutions working together for 13 years and cost $3 billion. Each genome is approximately 3 billion nucleotides. 2
of enterprises face significant roadblocks that hold them back from moving beyond cost reduction to faster time-to-market and better orchestration of their businesses.4
is the amount of server workload that will be virtualized in the cloud by the end of 2014. Cloud growth rates are 5x normal IT growth rates.3
20
60%
83%
3
300+

DISRUPTOR: Three quarters of Life Sciences enterprises have a weak digital-physical strategy –or none at all
Integrated digital-physical strategy
Limited digital strategy
No digital strategy
Source:Question B4–What kind of digital strategy does your enterprise have?; Global n=2,869; Life Sciences n=95 1 4
28%
51%
21%
have an integrateddigital-physicalstrategy
Life Sciences
Digital Strategy
21%
Collaborative research teams that are geographically dispersed need to swiftly communicate and collaborate with one another as well as with third-party commercial or academic research groups.
31%
Underperformers
39%
Outperformers
85%
increase
Integratingthe digital backbone to “customer” effecting systems reaps rewards
Benefits of Integrated Digital Strategy

DISRUPTOR: Life Sciences CxOsunderstand the need to collaborate more extensively across internal and external boundaries in the future
Source:Question B2–How strong is your collaboration with partners/suppliers and employees?; Global n=1,390; Life Sciences n=95 to 97 1 5
39% of outperforming Life Sciences enterprises promote the development and usage of employee networks. Only 31% of underperforming enterprises do.
Partners/suppliers
Employees
48% 84%
Today 3–5 Years
34%82%
Today 3–5 Years
47%
48%
84%
34%
82%
141%
High level of collaboration with partners and employees needed
75%
increase
increase

DISRUPTOR: Industry Leaders are Struggling with Synchronization and Timely File Transport
Does your company have the ability to synchronize its critical internal and external systems?
6
of organizations regard synchronization as critical to their overall success …
17%
83%
Yes, encompassing everyone
No, not with everyone
3%
34%
73%
Not critical
Neutral
Critical
Value chain synchronization survey –Feb, 2012 for IBM
… however, only can
synchronize their internal and external systems to drive business performance and success
17%
73%

Agenda
Disruption for the Life Sciences Industry
Why IBM Asperais the Right Response to Industry Change
7

IBM AsperaSolutions Add Key Capabilities In IBM’s Market Leading Data Movement and Managed File Transfer Capability
Community-Centric
Multi-protocol edge gateway for universal connectivity to the business community
Person-Centric
File sync and share
Emerging Use Cases
Governance
Security
Common perimeter services, proxy and authentication
Actionable visibility for business, operations and compliance
Direct to Cloud
…
System-Centric
Automated, reliable, secure transfers for system integration
High-Speed
Large file/data set transfer and sync
8

Smarter Commerce: IBM Aspera Capabilities Resolve Life Sciences Imperatives
R&D Transformation
•Collaborative Research and Data Set Sharing
•Data transfers
"With Aspera, we get a full suite of solutions that accelerates almost every aspect of our highly customized workflows, giving us a key strategic advantage over others...” 1
-VP of Infrastructure & Technical Services
9
Improve R&D Processes

of organizations report they are
challenged to move big data quickly and
efficiently enough to meet business requirements.1
Smarter Commerce: IBM Aspera Capabilities Accelerate Business Value with Cumulative Benefits
According to a recent study, IBM Smarter Commerce pays back $12.05 USD for every $1 USD spent.4
bandwidth utilization by FTP on high speed lines over distance without IBM Asperatechnology.2
The number of hours it now takes to setup for large file projects, down from 2-3 weeks without IBM Asperatechnology.4
Transcontinental file transfer speed improvements after deploying a High Speed File Transfer & Sync with no hardware or network upgrades required.3
88%
100x
<3%
2-3
10

Agenda
Disruption in the Life Sciences Industry
Why IBM Aspera is the Right Response to Industry Change
11

IBM Aspera for Chemicals & Petroleum Operations and Technology Executives
ImproveR&DProcesses
High Speed Data Sharing & Distribution
High Speed Worldwide Data Transfer
COOCollaboration Leader
Quality Assurance Lead________________________
CTOResearch Ops Lead
B2B Integration Leader________________________
FSS
HFT
Eliminate the bottlenecks of traditional TCP and physical data transport solutions by enabling ultra-secure IBM Aspera High-Speed File Transfer (HSFT) on premise and on the cloud to accelerate transfers to dislocated research and analysis facilities and data centers.
12
Increase flexibility and just in time collaboration capabilities of local and remote teams and personnel allowing highly secure mobile, web and desktop access to all assets through the IBM Aspera File Sharing Suite (FSS).
HSS
Utilizing IBM Aspera High Speed Sync (HSS) for extremely fast and efficient cloud, data center and on premise and off-shore/remote synchronization for sharing, distribution and disaster recovery.
High Speed Data Center & Cloud Sync
CIOCloud Systems Leader
VP of Data Centers________________________

13
TO
FROM
FSS
HIGH SPEED DATA SHARING AND DISTRIBUTION
SmarterCommerceB2B
Inconsistent & Slow
Coordinated & Fast

reduction in transmit time from days to minutes
reduction in cost in physical shipping and transportable hardware costs
FSS
HIGH SPEED DATA SHARING & DISTRIBUTION
As provider bioinformatics and healthcare data collection and processing, a better file transfer solution was needed that could integrate directly into the tumor research consortium web portals and that would provide fast transfer speeds, security, and data integrity.
14
genomic research

Information Needs To Be Coordinated With A Growing Set of Participants:
Big data analytics team and software engineers
External partners, researchers and educational institutions
Journal audit and review team
Mark Has To Deal With A Growing Set Of Data Types As Well:
QA scientists at experiment origin
Experiment design and process scientists
Genome re-sequencing, targeted re- sequencing, RNASeq, small RNA and De novo assembly files
Sensor and experiment machinery logs
Large database sets for neuroscience,
and systems biology data
Video and imaging studies
FSS
Speed and security issues hamper most file sharing solutions today –IBM Aspera File Sharing Suite with FASP™ technology addresses all these issues and more to help collaborators do more. Faster.
HOW TO MAKEIT HAPPEN:
DOMORE
FASTER
KNOWMORE
15
LIFE SCIENCES DATAFILE SIZES AND VOLUMES ARE EXPLODINGFOR EXECS LIKE MARK

WITH THE POWER OF IBM ASPERA FILE SHARING SUITE MARK HAS TOOLS TO COLLABORATE AT SPEEDWITH HIS EXTENDED QUALITY ASSURANCE TEAM
Browser plugin or installed desktop or mobile app
Supports significant files sizes including big data analysis, genomic and bioinformatics research.
DESKTOP & BROWSER ACCESS
MULTI PROTOCAL SIGN ON SUPPORT
LARGE FILE SUPPORT AT SPEED
APIs FOR SEAMLESS WORKFLOW
FSS can be integrated to existing collaboration systems
Easily integrated into mobile and cloud platform solutions.
All files for shared individuals and teams can be synced across all access points
FSS
Supports local (SAML) or managed (LDAP) login compliance or both.
Provides encrypted transfers and federated data access
Accelerate the sharing of information between people, systems and communities and provide high performance distribution and synchronization of large files while lessening the security risk from sharing file based information
DOMORE
FASTER
KNOWMORE
16

THE IBM ASPERA FILE SHARING SUITE HELPS MARK’S TEAM COMPLY FASTERWITH NEW RESEARCH DEMANDS AND IMPROVED USER EXPERIENCE
Mark is the QA executive lead for a genomic research analysis and distributioncompany working with a large research consortium on new cancer experiments.
FSS
IBM Aspera File Sharing Suite creates a new paradigm of speed and agilityfor sharing between life sciencesprofessionals.
DOMORE
FASTER
KNOWMORE
17
QUALITY
ASSURANCE
Mark can quicklycreate a new shared spacefor the research team that is secure and easily accessible from mobile, web or integrated into existing collaborationsolutions.
Safety reports and video analysis of experiment operations are now able to be sent across the satellite uplinkin record time for review and analysis.
External researchers and data partners are able to download large files without worrying about older versions or extra versionsbeing sent via e-mail since everything is consolidated and versioned.
Research teams can access reports requiring design changes and can securely exchange experimental filesfor improved and updated machinery and operations improvements quickly and easily.
With individual user authentication and file history and auditingthe QA organization has a complete history of document creation and retrieval.

FASP TECHNOLOGY IS THE SECRET SAUCE THAT MAKES IBM ASPERA FILE SHARING SUITE UNMATCHED FOR LIFE SCIENCES TEAM COORDINATION
Bit AES encryption in which the key is re- initialized throughout the duration of the transfer using cipher feedback to protect
against all standard attacks.
Reduction in transfer times – transfer that was taking 20 minutes now less than 1 min
Increase in total data shared per day -from 5GB to 190GB
HIGH SPEED MARKETING COORDINATION
IBM Aspera’spatented FASP transport technology is a proven standard for the high- speed movement of large files or large collections of files over wide area networks (WANs).
FSS
DOMORE
FASTER
KNOWMORE
20x
38x
128
18

19
TO
FROM
HFT
HIGH SPEED WORLDWIDE DATA TRANSFER
Limited & Inefficient
Boundless & Efficacious
SmarterCommerceB2B

Increase in speed over FTP for file delivery across the WAN
600%
A research center North America that uses the powerful tools of genomics and bioinformatics to understand, study, and generate data for the international scientific community needed a faster and more secure way to distribute 20GB+ data sets internationally than physical shipments.
20
“Using Aspera, we don’t have to handle and ship drives. We can move all the data online. We have gone from spending 4 hours packing disks to 5 minutes using Aspera.” – Senior Software Engineer
global transfers
HFT

LIFE SCIENCES OPERATIONS EXECUTIVES LIKE BRYANARE FACING LARGER FILE SIZES AND CONSTRAINED BANDWIDTH OPTIONS
US National Center for Biotechnology Information in Bethesda, Maryland. Each day last year, the EBI received about 9 million online requests to query its data, a 60% increase over 2011. 1
Analysis locations today can be 1000s of kilometers away from researchers.
Next-Generation Sequencing means larger data sets than ever before 2
Researchers like BGI have over 150 genome sequencing instruments working around the clock generating massive amounts of data for analysis. 1
21
New research technologies create tens of gigabytes of data for each experimental run. Asperasoftware moves these large genomic data sets across the globe, achieving max transfer speeds and enabling more productive research and faster time to market.
HFT
DOMORE
FASTER
KNOWMORE

IBM ASPERA HIGH SPEED FILE
TRANSFER HELPS BRYAN’S
ORGANIZATION UNLOCK LIMITS TO
FILE TRANSFER SPEED AND DISTANCE
Bryan’s team can utilize
web, mobile, desktop or
server clients for ingestion
to the cloud, local storage or
both.
Transfer distances and
bandwidth become non-issues
with 99% network
utilization.
Transfer large file sets like
genomic data from
experiments up to 1000x
faster than before.
Security is a high priority at
life sciences firms and Bryan
can take comfort that his
solution is compliant.
TRANSFER
HOW TO MAKE
IT HAPPEN:
DO
MORE
KNOW FASTER
MORE
• File workflow
and routing
• Advanced user
and server
management
• Complete
monitoring and
reporting
• High-availability
configuration
(active/active or
active/passive)
• Extensive API
support for
embedding into
existing
transport
solutions
HFT
22

IBM ASPERA HIGH SPEED FILE TRANSFER HELPS BRYAN’S TEAM PROVIDE BETTER RESEARCH EXPERIENCES THAN EVER BEFORE
Bryan’s team is supporting a new medical research operation in Africa for a new client. The location is remote and connectivity is limited to VSAT and 2G cellular services. Physical transport of collected data is too expensive and takes too long to meet SLA requirements.
DOMORE
FASTER
KNOWMORE
23
SUPER COMPUTING RESEARCH
CENTER
Bryan’s team does not have the budget or the time to make any significant improvements to his company’s physical network hardware or cable infrastructure but they must move all the research data for analysis within 12 hours after collection to meet SLA deadlines.
Security requirements for the content is at an all-time high as world reaction to mis- communicated data is a concern and overall security is regulated by the local and international governments.
Bryan’s group decides to deploy the IBM Aspera High Speed File Transfer solution in order to overcome bandwidth limitations with traditional FTP file transfers and maximize the network they have.
The team is able to deliver very large data sets, imaging and video for analysis and research to their data centers all over the world in record time.
Bryan’s team now has the ability to move huge (100GB+) data sets faster and more securely than ever before to cloud or directly to the companies super computing data centers for analysis around the world.
HFT

IBM ASPERA PATENTED FASP TECHNOLOGY DELIVERS BLISTERING SPEEDS REGARDLESS OF TRADITIONAL FILE AND NETWORK LIMITATIONS
Maximum transfer speed, bandwidth utilization and maximum I/O throughput on any storage platform regardless of number or size of files
DOMORE
FASTER
KNOWMORE
•Deployed across enterprise servers, private, public and hybrid clouds
•Powerful and flexible security model combining authorization, user management, and access control
•Search, filtering, and sorting capabilities
HFT
24
FILE SIZEINDEPENDENT
DISTANCEINDEPENDENT
Transfer, replicate or synchronize your data in all types of scenarios: one- to-one, hub and spoke, unidirectional and multi- directional
INFRASTRUCTURE AGNOSTIC
Locate your big data anywhere and move it seamlessly with high-speed, secure transfers
ANY DEPLOYMENT MODEL
ON PREMISES
CLOUD
HYBRID

25
HSS
Speedy & Reliable
Sluggish & Unpredictable
SmarterCommerceB2B
TO
HIGH SPEED DATA CENTER AND CLOUD SYNC

Weeks for full system implementation and turn up
average throughput on data transfer rates between synchronized sites
Multinational company active in over 180 countries needed a way to synchronize petabyte sized file systems with 100s of millions of files across the country and around the world quickly and securely.
2
8Gbs
HIGH-SPEED DATA CENTER AND CLOUD SYNC
HSS
disaster readiness

Reduce the time to send and receive secure files even across remote or poor data connections at up to 1000x faster than standard protocols like FTP.
Cloud usage and sensor growth means Life Sciences must synchronize more data than ever between data centers and user systems
Experiment photo/video, logs and sensor dump data archival
External partner/equipment manuals, firmware, updates, etc.
Data migration of NGS research for analysis and consolidation
Remote sync of data centers and servers for disaster recovery
DATA SETS GET ARE GETTING BIGGER AND SCIENCE IS DRIVINGMORE REMOTE LOCATIONS AND BIG DATA SERVICES
HSS
DOMORE
FASTER
KNOWMORE
LARGE DATA FILES & SETS

IBM Aspera Sync intelligently recognizes changes and file system operations, instantaneously synchronizing of millions of files and multi-terabyte file sets at multi-gigabit transfer speeds to remote peers with encryption in transit and at rest that assures maximum security of business- critical digital assets.
IBM ASPERA HIGH SPEED SYNC DELIVERS FASTER, MORE RELIABLY AND MORE SECURELY THAN RSYNC
Exabytesof data are created every single day across the globe
2.5
1000x
IBM Aspera High Speed Sync is up to 1000 times faster than traditional rSync
40%
Current per annum growth rate in enterprise storage each year
HSS
DOMORE
FASTER
KNOWMORE

IBM Aspera FASP technology is an evolutionary leap in rapid file movement virtually eliminating time constraints and throughput bottlenecks on even the most fragile and underpowered networks.
IBM ASPERA HIGH SPEED SYNC GENERATES SIGNIFICANT SPEED IMPACTS WITHOUT ANY HARDWARE OR NETWORK ENHANCEMENTS
in network utilization.
From 2% to 99% for file transfers.
Transfer that was taking 10 hours now takes 26 minutes.
in hardware and network upgrades. Asperasolutions are all software based.
20X
+ FASTER
$0
INVESTMENT
97%
INCREASE
HSS
DOMORE
FASTER
KNOWMORE

Agenda
Disruption in the Life Sciences Industry
Why IBM Aspera is the Right Response to Industry Change
30

IBM is dedicated to your success, in your industry
Unparalleled Industry Expertise
•Accelerate solution design and thorough business process expertise
•Reduce project risk with reusable implementation patterns and support for industry standards
•Providing services to the top life sciences organizations worldwide.
Extensive Industry Support Community
•IBM partners with the top life sciences research organizations in the worldto invest in innovative design, functionality, and integration
•Dedicated resources within Global Business Services with an average of more than 10 years of experience
•Services organization closely aligned with software products to effectively translate technology into business outcomes
Significant Technical Investment
•Over $3 billion invested in the last 3 years to create a truly smarter approach to commerce
•Integrated products for easier implementation and increased speed to value
•Synchronized product roadmaps across software portfolio
31

IBM Aspera In Life Sciences

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