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•Member of the lily family.
•240 species of Aloe .
•Succulent, perennial,
evergreen.
•Native to Africa, but is now
widespread.
•It is a bitter herb with a wide
range of medicinal properties.
•It contains over 75 compounds,
Known as the “lily of the
desert”.
Considered the “plant of
immortality” by many native
peoples.
Very long history of medical
usage…











2200 B.C.- Mentioned on
Sumerian clay tablets.
1550 B.C.- The Ebers Papyrus
states 12 recipes for mixing Aloe
with other agents to treat human
disorders.
Usually the whole leaf was
ground and mixed with another
medicinal agent








First modern medical paper published in
1934.
 Described how the whole leaf was
used to treat radiation dermatitis.
Many papers published in the 20th century
describing a wide range of medicinal
properties.

Reports have mainly focused on the
antidiabetic, anticancer, and
antimicrobial properties of the whole
leaf, gel, or juice of the plant.
Many species of Aloe have been studied.


Vitamins









Mono and poly
saccharides, glucomannans

Anthraquinones





Most important: Aloin,
and Emodin

Cholesterol,
Campesterol, Sisosterol,
and Lupeol

Salicyclic acid




3% of Aloe Vera gel

Fatty Acids




Inert except when in
topical treatments

Saponins


Ca, Na, K, Mg, Mn, Cu,
Zn, Cr, and Se

Sugars

Lignins


Lipases, proteases, kinases

Minerals




Vitamin D, A, C, E and
B12

Enzymes




Aspirin-like

Amino Acids


20 amino acids


Added because of known
rejuvenating action

Mode of Action:
 Polysaccachrides act as
moisturizers
 Stimulates the
fibroblasts to replicate
faster
 Smoothes skin because
sticks epidermal cells
together which
normally flake
 Interferes with
melanin deposit
production which lead
to “liver spots”




Decrease in blood glucose
due to stimulation of
insulin secretion
Decrease in cholesterol,
triglycerides,
phospholipids, and free
fatty acids from increased
clearance and decreased
transporters


50% gel leaf solution, complete inhibition
of Staphylococcus aureus
 Due to phenolics
 Efficacy of gel or leaf?
 S. aureus inhibited by both
 Other bacteria inhibited by
just leaf or gel




Shows increased healing effects on 2nd degree
burns

Anti-inflammation and wound healing
promotion
Vessels return to normal size quicker than with
untreated burns




When aloe is combined
with other antimicrobials, a wound heals
faster than with the antimicrobial alone.
Possibly due to its
moisturizing capability as
well.
Asian practice of
ingesting herbs to
support the immune
system
 May have a direct
inhibitory effect on
microbes
 Also, selectively
modulates cells of the
immune system

Gel and latex.

Gel- leaf pulp or
mucilage obtained from
the parenchymal tissue.

Latex- bitter, yellow
substance obtained from
pericyclic tubules just
beneath the outer skin
of the leaves. (otherwise
called ‘Aloe juice’)

These terms are often
confused by consumers.

Using a freshly cut leaf
is thought to be the
most effective treatment.

Dental Health and Hygiene
2.
Provides Rapid Soothing
3.
Aids in Healthy Digestion
4.
Immune Support and Function
Regulates Weight and Energy Levels
6.
Collagen and Elastin Repair
7.
Daily Dose of Minerals
8.
Daily Dose of Vitamins
9.
Anti-inflammatory Properties
10. Essential Amino Acids
1.

5.
AMIT PRAKASH SAHOO
 ROLL NO. – 3
 CLASS-X
SCHOOL-KV AVIKANAGAR





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Aloe vera

  • 1.
  • 2. •Member of the lily family. •240 species of Aloe . •Succulent, perennial, evergreen. •Native to Africa, but is now widespread. •It is a bitter herb with a wide range of medicinal properties. •It contains over 75 compounds,
  • 3. Known as the “lily of the desert”. Considered the “plant of immortality” by many native peoples. Very long history of medical usage…      2200 B.C.- Mentioned on Sumerian clay tablets. 1550 B.C.- The Ebers Papyrus states 12 recipes for mixing Aloe with other agents to treat human disorders. Usually the whole leaf was ground and mixed with another medicinal agent 
  • 4.    First modern medical paper published in 1934.  Described how the whole leaf was used to treat radiation dermatitis. Many papers published in the 20th century describing a wide range of medicinal properties.  Reports have mainly focused on the antidiabetic, anticancer, and antimicrobial properties of the whole leaf, gel, or juice of the plant. Many species of Aloe have been studied.
  • 5.  Vitamins      Mono and poly saccharides, glucomannans Anthraquinones    Most important: Aloin, and Emodin Cholesterol, Campesterol, Sisosterol, and Lupeol Salicyclic acid   3% of Aloe Vera gel Fatty Acids   Inert except when in topical treatments Saponins  Ca, Na, K, Mg, Mn, Cu, Zn, Cr, and Se Sugars Lignins  Lipases, proteases, kinases Minerals   Vitamin D, A, C, E and B12 Enzymes   Aspirin-like Amino Acids  20 amino acids
  • 6.  Added because of known rejuvenating action  Mode of Action:  Polysaccachrides act as moisturizers  Stimulates the fibroblasts to replicate faster  Smoothes skin because sticks epidermal cells together which normally flake  Interferes with melanin deposit production which lead to “liver spots”
  • 7.   Decrease in blood glucose due to stimulation of insulin secretion Decrease in cholesterol, triglycerides, phospholipids, and free fatty acids from increased clearance and decreased transporters
  • 8.  50% gel leaf solution, complete inhibition of Staphylococcus aureus  Due to phenolics  Efficacy of gel or leaf?  S. aureus inhibited by both  Other bacteria inhibited by just leaf or gel
  • 9.   Shows increased healing effects on 2nd degree burns  Anti-inflammation and wound healing promotion Vessels return to normal size quicker than with untreated burns
  • 10.   When aloe is combined with other antimicrobials, a wound heals faster than with the antimicrobial alone. Possibly due to its moisturizing capability as well.
  • 11. Asian practice of ingesting herbs to support the immune system  May have a direct inhibitory effect on microbes  Also, selectively modulates cells of the immune system 
  • 12. Gel and latex.  Gel- leaf pulp or mucilage obtained from the parenchymal tissue.  Latex- bitter, yellow substance obtained from pericyclic tubules just beneath the outer skin of the leaves. (otherwise called ‘Aloe juice’)  These terms are often confused by consumers.  Using a freshly cut leaf is thought to be the most effective treatment. 
  • 13. Dental Health and Hygiene 2. Provides Rapid Soothing 3. Aids in Healthy Digestion 4. Immune Support and Function Regulates Weight and Energy Levels 6. Collagen and Elastin Repair 7. Daily Dose of Minerals 8. Daily Dose of Vitamins 9. Anti-inflammatory Properties 10. Essential Amino Acids 1. 5.
  • 14.
  • 15. AMIT PRAKASH SAHOO  ROLL NO. – 3  CLASS-X SCHOOL-KV AVIKANAGAR  

Notas del editor

  1. Vitamin A is antioxidant Vitamin B12 very rare in plants and so this is very important for vegetarians Enzymes: when taken orally help with digestion by breaking down sugars and fats, one in particular, Bradykinase, reduces inflammation when applied topically to skin Minerals: many needed for proper functioning of various enzyme systems in metabolic pathways Sugars: come from mucilage layer of plant, help enhance the immune system and help to detoxify, some form a barrier in gut to prevent absorption of unwanted materials, gluco-mannans: not broken down in gut and appear in blood stream in same form where they are able to help regulate immune system, topically the sugars are main moisturisers Anthraquinones: there are 12 of these phenolics, found in the sap, aid in absorption in GI tract, have anti-microbial, anti-viral and pain killing activity Lignins: gives aloe a penetrating effect when topical so can be absorbed through skin Saponins: capable of cleansing and have antiseptic properties, also antimicrobial activity Fatty Acids: involved in anti-inflammatory Amino acids: 20 out of 22 amino acids including 7 of the 8 essential amino acids the body cannot synthesize
  2. Fibroblasts are what produce collagen and elastin fibers so skin becomes more elastic and less wrinkled Also can help remove already establish liver spots\\
  3. The comparative antimicrobial activities of the gel and leaf of Aloe vera were tested against Staphylococcus aureus, Pseudomonas aeruginosa, Trichophyton mentagraphytes, T. schoeleinii, Microsporium canis and Candida albicans. Ethanol was used for the extraction of the leaf after obtaining the gel from it. Antimicrobial effect was measured by the appearance of zones of inhibition. Antimicrobial susceptibility test showed that both the gel and the leaf inhibited the growth of S. aureus ( 18.0 and 4.0 mm, respectively). Only the gel inhibited the growth of T. mentagrophytes ( 20.0 mm), while the leaf possesses inhibitory effects on both P. aeruginosa and C. albicans. The results of this study tend to give credence to the popular use of both Aloe vera gel and leaf.
  4. * Throughout test, the vessels were more dilated and had increased postcapillary venular permeability
  5. Full-thickness excised wounds were created on the dorsum of Sprague-Dawley rats under anaesthesia. The wounds were treated with topical agents three times daily for fourteen days, then observed until healed. Used, saline contol, placebo (aqueous cream) control, silver sulphadiazine (SSD) cream 1%, SSD 0.5%, SSD 1% with Aloe vera, SSD 1% with nystatin, nystatin. Wound healing was delayed by saline and SSD. Nystatin and Aloe vera, when added to SSD, reversed that effect. These data suggest that a dry wound (saline) heals slowly. Infection control without delay of wound healing is most appealing and clinical trials are planned.
  6. The current practice of ingesting phytochemicals to support the immune system or to fight infections is based on centuries-old tradition. While it may have a direct inhibitory effect on microbial organisms, It also selectively modulates cells of the immune system. They will study the influence on immune cells as well as microbes to provide useful insights to the development of potentially useful new pharmacological agents.