PREPARED BY: MUHAMMAD ARIFF B. MAHDZUB BACHELOR MEDICINE AND SURGERY (MBBS) UNIVERSITY COLLEGE SHAHPUTRA, KUANTAN

1. 1
Example of acute and
chronic inflammationPROBLEM BASED LEARNING (PBL)
PREPARED BY: MUHAMMAD ARIFF B. MAHDZUB
BACHELOR MEDICINE AND SURGERY (MBBS)
UNIVERSITY COLLEGE SHAHPUTRA, KUANTAN

2. Example of diseases associated
with acute inflammation
• acute bronchitis
• sore throat from a cold or flu
• acute appendicitis
• acute tonsillitis,
• acute infective meningitis
• acute sinusitis

3. Acute bronchitis

4. Sore throat

5. Acute appendicitis

6. Acute tonsillitis

7. Acute infective meningitis

8. Acute sinusitis

9. Example of diseases associated
with chronic inflammation
• Alzheimer’s Diseases
• Rheumatoid Arthritis
• Chronic peptic ulcer
• Asthma
• Hypersensitivity

10. Alzheimer’s disease

11. Rheumatoid arthritis

12. Rheumatoid arthritis

13. Chronic peptic ulcer

14. Asthma

15. Hypersensitivity

16. Body Reaction
Towards
Hypersensitivity

17. Hypersensitivity
A state of altered reactivity in which the body reacts
with an exaggerated immune response to a foreign
substance
There are 4 types :
1. Type I (Anaphylactic) reactions
2. Type II (Cytotoxic) reactions
3. Type III (Immune complex) reactions
4. Type IV (Cell-mediated) reactions

18. Type 1 (Anaphylactic) reactions
• Occur within minutes of exposure to antigen
• Allergen attached to IgE antibodies
• IgE binds to mast cells and basophils, causing them
to undergo degranulation and release several
chemical mediators :
• histamine – dilates and increases permeability of
blood vessels (swelling & redness)
• Prostaglandins – contraction of smooth muscle &
increased mucus secretions (control blood pressure)