1. Presented by Dr. B. Victor, St. Xavier’s College, Palayamkottai-627002,India. Functional Organization of the Immune System: 2.Immunoreactive Cells

3. Blood cell categories Formed elements of the blood Nucleated cells Non-nucleated cells Leucocytes Erythrocytes Thromphocytes Polymorphonuclear cells Eosinophils Neutrophils Basophils Monocytes Lymphocytes Natural killer cells

5. Sub-categories of Leucocytes Leucocytes Granulocytes (Polymorphonuclear cells) Agranulocytes (Mononuclear cells) Eosinophils Neutrophils Basophils Monocytes Lymphocytes Natural killer cells

9. Granulocytes & Agranulocytes Basophil Eosinophil Neutrophil Lymphocyte Monocyte

18. Immunocytic system Immunocytic system Cell mediated immunity Humoural Immunity Production of Lymphokines Production of Antibodies T-Lymphocytes B-Lymphocytes (Plasma cells)

20. Origin of cells of the immune system

22. Lymphocytes Lymphocytes T-Lymphocytes B-Lymphocytes T-helper cells T-suppressor cells T-cytotoxic cells T-delayed hypersensitivity cells Plasma cells B-memory cells

28. Human T-lymphocyte (SEM x12,080).

30. T Lymphocytes

33. B cells mature into plasma cells that produce antibodies.

36. Plasma Cell

39. Natural Killer Cells

40. Natural killer cell, Killer cell and cytotoxic T lymphocytes

41. B cell-T cell interaction

42. B cell-T cell interaction

46. Antigen receptors expressed as transmembrane molecules on B and T lymphocytes

52. Antigen Presenting cell (APC)

53. Phagocytes and Their Relatives

60. Macrophage attacking E.coli (SEM x8,800 ).

61. Normal anti-bacterial action 1. PHAGOCYTIC CELL ENGAGES MICROBE 2. PHAGOCYTOSIS OF THE MICROBE 3. DESTRUCTION OF THE MICROBE

66. Thank you