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2Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Introduction
Changing patient expectations represents a shifting landscape, together with the
increasing influence of social media, plus heightened government regulatory activity and a
growing trend of alliances and acquisitions.
Pharmaceutical companies need to respond dynamically to this evolution by implementing
new business models. Next generation business models must address a number of key
factors to position themselves for long-term success, one of which is to listen and
ultimately engage in meaningful dialogue with consumers and stakeholders.
In this white paper, we seek to explore:
• Key challenges facing pharmaceutical companies in their forays into social listening
• Benefits of social listening illustrated with reference to a number of case studies drawn
from a selection of therapy areas
• Recommendations around how to get started and the role Brandwatch and PharmiWeb
Solutions can take to help you achieve business success
3Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
INTRODUCTION ...................................................................................................... 2
The Rise of the Empowered Patient.......................................................................................... 4
High Consumer Expectations.................................................................................................... 4
KEY CHALLENGES FOR PHARMA ....................................................................... 5
Listening as Liability .................................................................................................................. 5
Adverse Event Reporting ........................................................................................................... 5
Overcoming AE Challenges....................................................................................................... 6
SOCIAL MEDIA & ADVERSE EVENT REPORTING ............................................. 7
The AE Test ................................................................................................................................. 7
The Results.................................................................................................................................. 7
The Opportunity .......................................................................................................................... 9
Scale & Granularity..................................................................................................................... 9
Unprompted Value ...................................................................................................................... 9
The Value of Listening to Non-HCP Groups........................................................................... 10
BENEFITS OF LISTENING: OTHER USE CASES .............................................. 11
Brand Reputation...................................................................................................................... 11
Evaluate & Inform Engagement............................................................................................... 11
Campaign Evaluation ............................................................................................................... 11
Understand Market Trends ...................................................................................................... 11
Consumer Insights ................................................................................................................... 11
New Market / Global Analysis .................................................................................................. 12
EXAMPLE CASE ONE........................................................................................... 13
Mapping Key Opinion Leaders in Immuno-Oncology ........................................................... 13
Segmenting Influencers ........................................................................................................... 13
EXAMPLE CASE TWO.......................................................................................... 16
Leveraging Insights to Drive Messaging & Channel Strategy................................................ 16
Channel Insights ....................................................................................................................... 16
Messaging Insights................................................................................................................... 17
Granular HCP Insights.............................................................................................................. 18
GETTING STARTED.............................................................................................. 20
Brandwatch ............................................................................................................................. 20
PharmiWeb ............................................................................................................................. 20
APPENDIX ............................................................................................................. 21
4Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Market Context - Empowered Patients
THE RISE OF THE EMPOWERED PATIENT
We are seeing a new dynamic in the healthcare setting, with the rise of the empowered
patient in contrast to the passive patient of the past. The internet has made medical
information more accessible than ever before, boosting health literacy and connecting
people around the world with similar symptoms and conditions.
Today, patients and caregivers are part of a wider, connected ecosystem where social
media is a key resource across multiple devices.
In the US, for example1
, over one third of consumers manage their own health and are
using social media to help them make important healthcare decisions. Social media
platforms provide a new avenue for information and dialogue.
In addition, the virtual environment enhances communications by creating a comfortable
way to exchange information.
HIGH CONSUMER EXPECTATIONS
Companies are being held to increasingly high standards set by organizations that excel
at listening and responding, such as Virgin, Dell, Starbucks, Southwest Airlines and others.
These companies are setting the bar not just for their direct competitors, but also across all
sectors, including the pharma industry.
1
Pew Internet: Health, 2013
5Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Key Challenges for Pharma
LISTENING AS LIABILITY
Although a few pharmaceutical companies have begun taking steps to listen to social
media, the sector still generally lags behind many other industries in social media use.
This is largely due to the ‘listening as liability’ mindset that comes primarily from
compliance concerns surrounding adverse event (AE) reporting in a heavily regulated
environment, and also doubts about how to measure the return-on-investment
(ROI) for such initiatives.
ADVERSE EVENT REPORTING
Many pharmaceutical companies fear that being involved in social conversations will
increase the number of adverse drug experience reports and force them to conduct
countless investigations that could be costly and damaging. This concern is exacerbated
by the fact that current regulations and guidelines from the FDA (and ABPI) fail to provide
clear guidelines around enforcement and pharmaceutical companies’ obligations to report
AEs identified through social channels.
Currently, FDA guidelines2
give 4 parameters for submitting information about adverse
experiences: the pharmaceutical company should have knowledge of
• an identifiable patient
• an identifiable reporter
• a specific drug or biologic involved in the event
• an adverse event or fatal outcome
2
Guidance Interactive Promotional Media, 2014
6Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
OVERCOMING AE CHALLENGES
Our experience, however, is that adverse event reporting through social media channels
very rarely presents an issue for pharmaceutical companies.
This is for a number of key reasons.
1. Report AEs found, not “go looking for AEs”
The requirement to report on any naturally found AEs does not mean actively searching
for as many AEs as possible. It is perfectly legitimate for pharma companies to investigate
their brands’ footprints online and not read each mention in detail.
2. Many potential AEs in social media are non-reportable
An AE can only be reported if the individuals involved can be identified/located. Often
online authors speak anonymously, meaning that the AE could not actually be reported.
3. There simply aren't as many branded AE cases as you might think
The majority of non-HCP online authors using/exposed to the medication, and likely to mention
a product AE, tend to use generic terms rather than specific drug or manufacturer names.
7Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Social Media & Adverse
Event Reporting
THE AE TEST
In order to more rigorously asess and exemplify these points, we conducted a test using
real social data for diabetes (one of the highest volume therapy areas).
We chose 24 of the most frequently used diabetes drug brands* and built a search
to actively search for AEs connected to them. This approach was designed to create
a “worst case scenario” for finding a high volume of AEs, in order to measure the impact
this could have on the business in terms of a time investment.
These mentions were read and categorised: Firstly, were they genuine AEs? Secondly,
what kind of AE is this, and is it reportable? Each day, our analyst logged their time to
complete this task.
THE RESULTS
Across the 2 weeks there were 82 mentions
flagged in total as potential AEs for the 24
brands. Only 17 of these were real AEs, and
only 4 were reportable (see Fig. 1). That
equates to an average of 2 AEs a week in
total for the 24 brands.
The process of categorising the AEs did not
prove time consuming, taking on average
just 4 minutes per day. Remembering that
the results of this study reflect the time taken
to monitor potential AEs for 24 widely taken
medications, it’s clear that whether a
pharma company elects to take a proactive
or incidental approach to AEs during a social
media study, the likely impact on project
scope is low to negligible.
*Based on information found on Webmd.com & Diabetes.co.uk
8Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Potentially Reportable
Non- Reportable
9Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Benefits of Listening:
Research Tool
THE OPPORTUNITY
In spite of the heavy constraints around pharmaceutical companies’ ability to speak
to their customers and the risks surrounding AE reporting, companies still have a lot
to gain by listening to the conversation that is already taking place. The most immediate
benefit that social media has to offer pharmaceutical companies is as a research tool.
Listening is the first step in effective communication and using social media for
research does not involve infrastructure changes or heavy investment. Conversations
provide a scale more similar to questionnaires, allowing for more robust quantitative
analysis techniques.
SCALE & GRANULARITY
Consumer conversations in social media frequently go into considerable detail about
their lives, situations and experiences, providing granular insights akin to those possible
in focus groups. The large number of online authors and conversations provide a scale
more similar to questionnaires, allowing for more robust quantitative analysis techniques.
UNPROMPTED VALUE
Social media data is distinct from traditional commercial research methodologies such
as questionnaires and focus groups as its unprompted nature reduces response bias.
By removing the researcher direction and allowing consumers to speak freely for
themselves in a non-research environment, social media provides a truer picture
of the online authors’ interests and priorities.
Lastly, unprompted data allows for the discovery of potential “unknown unknowns”.
The researcher does not have to know the issue exists to ask about it; important topics
will surface naturally from a data-led analysis.
10Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
THE VALUE OF LISTENING TO NON-HCP GROUPS
Pharmaceutical brands searching for social listening frequently state that they only want
to listen to HCPs. While it is possible to listen to HCPs, they often speak behind privacy
walls in closed networks, which cannot be accessed for market research purposes.
There is a much larger volume of patient, caregiver, support worker, journalist and other
consumer conversation, which is also valuable, and a missed opportunity if excluded from
analysis. Understanding the views of these groups, in particular patients and caregivers,
provides pharma brands with an insight into the needs of the end users of their products.
11Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Benefits of Listening:
Other Use Cases
BRAND REPUTATION
Accurate automated or manual analysis of consumer sentiment and key conversation
drivers (using topic extraction or customized segmentation) can provide a clear
understanding of what different author groups want and expect from your
brand/category, and whether these expectations are being met.
EVALUATE & INFORM ENGAGEMENT
Social insight reports can help inform the planning and evaluation of engagements
(where permitted). Specifically, they help identify potential advocates and inform
optimal messaging, channel and timing for branded content.
CAMPAIGN EVALUATION
Social media analysis can be tailored to specific campaign objectives, whether
this is increasing awareness, driving direct response or shifting HCP perceptions.
By measuring changes in baseline brand conversation, social media analytics can
benchmark results and show the ROI of the campaign.
UNDERSTAND MARKET TRENDS
Social media can be used to analyze a whole treatment category or therapy area.
A broad industry view provides companies with a better understanding of their place
in the market, as well as potential challenges and opportunities for their brands.
CONSUMER INSIGHTS
Social consumer insight reports can go beyond how your consumers feel about your
brand and be used to understand them better as people.
Consumer groups can be segmented by life stage, attitude, interests, gender or location;
identifying common behaviors and priorities.
12Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
NEW MARKET / GLOBAL ANALYSIS
Social media is a powerful tool for understanding regional differences in culture and
attitudes toward different treatment categories and therapy areas. This can help brands
to inform their messaging strategy for different groups across both developed and
emerging markets.
13Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Example Case One
MAPPING KEY OPINION LEADERS IN IMMUNO-ONCOLOGY
The growing field of Immuno-Oncology was selected to demonstrate the value of social
media for mapping influential HCPs. This study reveals the different ways in which
potential KOLs in a given therapy area can be found and tracked within the Brandwatch
Analytics Platform. In this example, PharmiWeb has helped evaluate and compare
the advocacy and regulatory organisations, pharmaceutical manufacturers and
medical professionals.
SEGMENTING INFLUENCERS
“Once identified*, healthcare professionals and scientists/researchers can be further
filtered in order to determine their authority, engagement level in the subject and reach.
This allows for more targeting tracking of the writing of KOLs, and narrows down to strong
candidates for potential engagement through social. In this study, the healthcare/science
industry authors were segmented according to three variables:
1 Their speciality
2 The number of posts they’d written about Immuno-Oncology
3 The time period over which they engaged with the subject
The platform allowed those listing themselves as Oncologists to be identified and added to
an author panel for further tracking. The table below (Fig.3) shows the top 10 Oncologists
found discussing Immuno-Oncology over the past 21 months, ranked by the number of
followers. The key topics, volume trend and sentiment of this group could now be tracked
on an ongoing basis.
14Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
*Twitter profile and profession data gathered using the Brandwatch Demographics feature
HCP/Scientist Twitter authors were also segmented according to their engagement level
with Immuno-Oncology, both in terms of volume and over time. The chart below shows
the activity of the authors shown to be the most important based on both of these points.
A filter was applied to show only authors who had Tweeted at least twice about the
subject, and had done so in both halves of the time period.
Put differently, they had Tweeted at least twice from Jan – Nov 2013, and at least twice
between Dec 2013 – Sep 2014 about Immuno-Oncology.
The chart below shows the Total potential follower impressions of each of the HCPs
identified as the most engaged with Immuno-Oncology. This score is calculated based
on the total Twitter followers for each author, multiplied by the number of Tweets posted
by that author in the month. This allows brands to track
the impact of potential KOLs over time.
Once identified, further analysis of KOLs can reveal the most pertinent topics for these
groups in comparison with others. Similar identification and filtering practices can create
target groups of other KOL types, including journalists or key figures in the market.
15Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
16Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Example Case Two
LEVERAGING INSIGHTS TO DRIVE MESSAGING & CHANNEL STRATEGY
In this study, the aim was to discover the key author groups interested in HIV treatments,
to then inform messaging and channel strategy for relevant brands. The study began by
analysing the author groups, allowing the segments to emerge naturally from the data
to ascertain the true key interest groups.
Once found, these groups were studied in order to understand their key channels and
conversation drivers.
CHANNEL INSIGHTS
Figure 5. shows that conversation about HIV treatments occurred mostly on Twitter.
This was particularly the case for HCPs (see the following page for more details on this
activity). There was also a group of patients talking openly about their treatment on Twitter,
however patients were also the most likely author group to talk in online forums, driven by the
ability to speak anonymously. Support workers were the most likely to blog about treatment.
17Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
MESSAGING INSIGHTS
Figure 6. shows the overall benefits of treatment most likely to be discussed (for all author
groups combined). The treatment benefit that drove the most online conversation was
that a person receiving HIV treatment is less likely to transmit the virus (to a partner
or in utero). This was discussed 4% more than prolonging the life of the patient,
demonstrating the value of social research for checking assumptions.
Figure 7. shows the different priorities of the author groups around treatment benefits.
Over 60% of online mentions about reducing the likelihood of transmission were
actually posted by “other consumers”, suggesting that this could be a strong topic
for broader awareness campaigns, but would perhaps not resonate strongly in patient
group communications.
Patients were the most likely to be concerned with the ability to live a normal life when
on effective treatment, even more so than an extended one. Regaining normality could
therefore be a message likely to resonate with patient advocacy groups.
Combined with the channel insights from the previous page, this data could underpin
a wider social engagement strategy.
18Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
GRANULAR HCP INSIGHTS
In order to better understand the HCP conversation on Twitter, the authors were split
into their specialty groups. The pie chart in Fig.8 shows that almost 75% of mentions
were driven by Mental Health Professionals (including therapists and psychiatrists),
Nurses and General Practitioners.
This suggests that HCPs concerned with patient support/wellbeing could be a key
online target group with interest in HIV medication. The topic cloud in Fig.8 shows
the key words most frequently used by the HCPs on Twitter. Patient age was a
recurring discussion theme, with “babies”, “children”, “adolescents” and “adults”
emerging as key associated age groups.
The importance of emotional support for patients was underlined (“counselling”),
as well as the links between treatment and prevention of HIV.
Understanding existing topics of interest can inform the creation of compelling
content for the community.
19Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
20Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Getting Started
PharmiWeb and Brandwatch are well placed to help you in your social listening
efforts, whether you’re considering your first project or you’re looking to build on
a current initiative.
Brandwatch
Brandwatch is the world’s most sophisticated social listening and intelligence platform,
and offers by far the most flexible analytics available on the market. This helps leading
healthcare businesses customize the technology to the specific needs of a sector that
operates like no other.
To see how the Brandwatch Analytics platform can help your organization, arrange a
hassle-free product tour by visiting:
brandwatch.com/demo
PharmiWeb
PharmiWeb solutions has a wealth of expertise in the life sciences vertical, helping deliver
sector-specific, actionable insights and strategic marketing recommendations. It is a
specialist business that combines pharmaceutical sector experience with digital and
technology know-how and creative flair and has been serving the life sciences sector since
2003. PharmiWeb currently works with 8 out of the top 10 global pharma companies
Working with Brandwatch, PharmiWeb offers bespoke services to pharma organizations,
from listening program pilots to best practice training.
To understand more about how PharmiWeb can help you take advantage of social
listening, get in touch with natasha.gomer@pharmiweb.com.
21Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
Appendix
METHODOLOGY / LOCATING AES IN ONLINE MENTIONS
The Brandwatch Analytics platform using advanced Boolean operators to allow
the creation of sophisticated keyword searching.
For transparency, we have included an extract of our search query locating Adverse
Events (fig 10).
Here we have employed 2 techniques to locate AEs. We begin by searching for specific
mentions of “side effects” or general words for problem/trouble. We also search for
different ways a consumer might indicate that the drug was not having the desired effect:
“does nothing” or “no difference”. Finally, we search for the most commonly occurring
specific side effects related to this kind of medication (e.g. bloating, fatigue, dizziness).
Any of these terms must appear within 15 words of one of our chosen brand names in
order to appear in our data.
Fig.9 / Diabetes medication brands studied
• Actos • Actos • Actos • Actos
• Amaryl • Amaryl • Amaryl • Amaryl
• Avandia • Avandia • Avandia • Avandia
• Byetta • Byetta • Byetta • Byetta
• Diabeta • Diabeta • Diabeta • Diabeta
• Glucophage • Glucophage • Glucophage • Glucophage
Fig. 10 / Adverse Events Search Query Extract
("side effect" OR reaction OR reacted OR problem* OR trouble* OR "didnt work"
OR "didn't work" OR "not effective"~1 OR "no effect" OR "no difference" OR "no different"
OR "does nothing" OR "doesn't help" OR "didnt help" OR "didn't help" OR "doesnt help"
OR "doesn't work" OR "doesnt work" OR "no better" OR "not better"~1 OR "side effects"
OR stomach OR rash OR rashes OR "weight gain"~1 OR "weight gaining"~2 OR kidney
OR tired* OR fatigu* OR dizz* OR "metal taste"~1 OR "metallic taste"~1 OR gas OR gassy
OR bloat* OR diarr* OR (liver NEAR/5 (disease* OR problem* OR pain* OR issue*
OR discomfort*)) OR anaemi* OR ((swell* OR swollen*) NEAR/1 (ankle* OR leg* OR feet
OR foot)) OR "low blood sugar")) NEAR/15 (I OR me OR my OR myself OR mine OR im
OR ive OR her OR his OR their OR friend* OR boyfriend* OR girlfriend* OR husband*
OR wife* OR dad OR mum OR dads OR mums OR mom OR moms OR father*
OR mother* OR daughter* OR son? OR aunt* OR uncle OR cousin* )
Social Listening in the Pharmaceutical Industry

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Social Listening in the Pharmaceutical Industry

  • 1.
  • 2. 2Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Introduction Changing patient expectations represents a shifting landscape, together with the increasing influence of social media, plus heightened government regulatory activity and a growing trend of alliances and acquisitions. Pharmaceutical companies need to respond dynamically to this evolution by implementing new business models. Next generation business models must address a number of key factors to position themselves for long-term success, one of which is to listen and ultimately engage in meaningful dialogue with consumers and stakeholders. In this white paper, we seek to explore: • Key challenges facing pharmaceutical companies in their forays into social listening • Benefits of social listening illustrated with reference to a number of case studies drawn from a selection of therapy areas • Recommendations around how to get started and the role Brandwatch and PharmiWeb Solutions can take to help you achieve business success
  • 3. 3Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com INTRODUCTION ...................................................................................................... 2 The Rise of the Empowered Patient.......................................................................................... 4 High Consumer Expectations.................................................................................................... 4 KEY CHALLENGES FOR PHARMA ....................................................................... 5 Listening as Liability .................................................................................................................. 5 Adverse Event Reporting ........................................................................................................... 5 Overcoming AE Challenges....................................................................................................... 6 SOCIAL MEDIA & ADVERSE EVENT REPORTING ............................................. 7 The AE Test ................................................................................................................................. 7 The Results.................................................................................................................................. 7 The Opportunity .......................................................................................................................... 9 Scale & Granularity..................................................................................................................... 9 Unprompted Value ...................................................................................................................... 9 The Value of Listening to Non-HCP Groups........................................................................... 10 BENEFITS OF LISTENING: OTHER USE CASES .............................................. 11 Brand Reputation...................................................................................................................... 11 Evaluate & Inform Engagement............................................................................................... 11 Campaign Evaluation ............................................................................................................... 11 Understand Market Trends ...................................................................................................... 11 Consumer Insights ................................................................................................................... 11 New Market / Global Analysis .................................................................................................. 12 EXAMPLE CASE ONE........................................................................................... 13 Mapping Key Opinion Leaders in Immuno-Oncology ........................................................... 13 Segmenting Influencers ........................................................................................................... 13 EXAMPLE CASE TWO.......................................................................................... 16 Leveraging Insights to Drive Messaging & Channel Strategy................................................ 16 Channel Insights ....................................................................................................................... 16 Messaging Insights................................................................................................................... 17 Granular HCP Insights.............................................................................................................. 18 GETTING STARTED.............................................................................................. 20 Brandwatch ............................................................................................................................. 20 PharmiWeb ............................................................................................................................. 20 APPENDIX ............................................................................................................. 21
  • 4. 4Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Market Context - Empowered Patients THE RISE OF THE EMPOWERED PATIENT We are seeing a new dynamic in the healthcare setting, with the rise of the empowered patient in contrast to the passive patient of the past. The internet has made medical information more accessible than ever before, boosting health literacy and connecting people around the world with similar symptoms and conditions. Today, patients and caregivers are part of a wider, connected ecosystem where social media is a key resource across multiple devices. In the US, for example1 , over one third of consumers manage their own health and are using social media to help them make important healthcare decisions. Social media platforms provide a new avenue for information and dialogue. In addition, the virtual environment enhances communications by creating a comfortable way to exchange information. HIGH CONSUMER EXPECTATIONS Companies are being held to increasingly high standards set by organizations that excel at listening and responding, such as Virgin, Dell, Starbucks, Southwest Airlines and others. These companies are setting the bar not just for their direct competitors, but also across all sectors, including the pharma industry. 1 Pew Internet: Health, 2013
  • 5. 5Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Key Challenges for Pharma LISTENING AS LIABILITY Although a few pharmaceutical companies have begun taking steps to listen to social media, the sector still generally lags behind many other industries in social media use. This is largely due to the ‘listening as liability’ mindset that comes primarily from compliance concerns surrounding adverse event (AE) reporting in a heavily regulated environment, and also doubts about how to measure the return-on-investment (ROI) for such initiatives. ADVERSE EVENT REPORTING Many pharmaceutical companies fear that being involved in social conversations will increase the number of adverse drug experience reports and force them to conduct countless investigations that could be costly and damaging. This concern is exacerbated by the fact that current regulations and guidelines from the FDA (and ABPI) fail to provide clear guidelines around enforcement and pharmaceutical companies’ obligations to report AEs identified through social channels. Currently, FDA guidelines2 give 4 parameters for submitting information about adverse experiences: the pharmaceutical company should have knowledge of • an identifiable patient • an identifiable reporter • a specific drug or biologic involved in the event • an adverse event or fatal outcome 2 Guidance Interactive Promotional Media, 2014
  • 6. 6Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com OVERCOMING AE CHALLENGES Our experience, however, is that adverse event reporting through social media channels very rarely presents an issue for pharmaceutical companies. This is for a number of key reasons. 1. Report AEs found, not “go looking for AEs” The requirement to report on any naturally found AEs does not mean actively searching for as many AEs as possible. It is perfectly legitimate for pharma companies to investigate their brands’ footprints online and not read each mention in detail. 2. Many potential AEs in social media are non-reportable An AE can only be reported if the individuals involved can be identified/located. Often online authors speak anonymously, meaning that the AE could not actually be reported. 3. There simply aren't as many branded AE cases as you might think The majority of non-HCP online authors using/exposed to the medication, and likely to mention a product AE, tend to use generic terms rather than specific drug or manufacturer names.
  • 7. 7Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Social Media & Adverse Event Reporting THE AE TEST In order to more rigorously asess and exemplify these points, we conducted a test using real social data for diabetes (one of the highest volume therapy areas). We chose 24 of the most frequently used diabetes drug brands* and built a search to actively search for AEs connected to them. This approach was designed to create a “worst case scenario” for finding a high volume of AEs, in order to measure the impact this could have on the business in terms of a time investment. These mentions were read and categorised: Firstly, were they genuine AEs? Secondly, what kind of AE is this, and is it reportable? Each day, our analyst logged their time to complete this task. THE RESULTS Across the 2 weeks there were 82 mentions flagged in total as potential AEs for the 24 brands. Only 17 of these were real AEs, and only 4 were reportable (see Fig. 1). That equates to an average of 2 AEs a week in total for the 24 brands. The process of categorising the AEs did not prove time consuming, taking on average just 4 minutes per day. Remembering that the results of this study reflect the time taken to monitor potential AEs for 24 widely taken medications, it’s clear that whether a pharma company elects to take a proactive or incidental approach to AEs during a social media study, the likely impact on project scope is low to negligible. *Based on information found on Webmd.com & Diabetes.co.uk
  • 8. 8Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Potentially Reportable Non- Reportable
  • 9. 9Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Benefits of Listening: Research Tool THE OPPORTUNITY In spite of the heavy constraints around pharmaceutical companies’ ability to speak to their customers and the risks surrounding AE reporting, companies still have a lot to gain by listening to the conversation that is already taking place. The most immediate benefit that social media has to offer pharmaceutical companies is as a research tool. Listening is the first step in effective communication and using social media for research does not involve infrastructure changes or heavy investment. Conversations provide a scale more similar to questionnaires, allowing for more robust quantitative analysis techniques. SCALE & GRANULARITY Consumer conversations in social media frequently go into considerable detail about their lives, situations and experiences, providing granular insights akin to those possible in focus groups. The large number of online authors and conversations provide a scale more similar to questionnaires, allowing for more robust quantitative analysis techniques. UNPROMPTED VALUE Social media data is distinct from traditional commercial research methodologies such as questionnaires and focus groups as its unprompted nature reduces response bias. By removing the researcher direction and allowing consumers to speak freely for themselves in a non-research environment, social media provides a truer picture of the online authors’ interests and priorities. Lastly, unprompted data allows for the discovery of potential “unknown unknowns”. The researcher does not have to know the issue exists to ask about it; important topics will surface naturally from a data-led analysis.
  • 10. 10Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com THE VALUE OF LISTENING TO NON-HCP GROUPS Pharmaceutical brands searching for social listening frequently state that they only want to listen to HCPs. While it is possible to listen to HCPs, they often speak behind privacy walls in closed networks, which cannot be accessed for market research purposes. There is a much larger volume of patient, caregiver, support worker, journalist and other consumer conversation, which is also valuable, and a missed opportunity if excluded from analysis. Understanding the views of these groups, in particular patients and caregivers, provides pharma brands with an insight into the needs of the end users of their products.
  • 11. 11Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Benefits of Listening: Other Use Cases BRAND REPUTATION Accurate automated or manual analysis of consumer sentiment and key conversation drivers (using topic extraction or customized segmentation) can provide a clear understanding of what different author groups want and expect from your brand/category, and whether these expectations are being met. EVALUATE & INFORM ENGAGEMENT Social insight reports can help inform the planning and evaluation of engagements (where permitted). Specifically, they help identify potential advocates and inform optimal messaging, channel and timing for branded content. CAMPAIGN EVALUATION Social media analysis can be tailored to specific campaign objectives, whether this is increasing awareness, driving direct response or shifting HCP perceptions. By measuring changes in baseline brand conversation, social media analytics can benchmark results and show the ROI of the campaign. UNDERSTAND MARKET TRENDS Social media can be used to analyze a whole treatment category or therapy area. A broad industry view provides companies with a better understanding of their place in the market, as well as potential challenges and opportunities for their brands. CONSUMER INSIGHTS Social consumer insight reports can go beyond how your consumers feel about your brand and be used to understand them better as people. Consumer groups can be segmented by life stage, attitude, interests, gender or location; identifying common behaviors and priorities.
  • 12. 12Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com NEW MARKET / GLOBAL ANALYSIS Social media is a powerful tool for understanding regional differences in culture and attitudes toward different treatment categories and therapy areas. This can help brands to inform their messaging strategy for different groups across both developed and emerging markets.
  • 13. 13Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Example Case One MAPPING KEY OPINION LEADERS IN IMMUNO-ONCOLOGY The growing field of Immuno-Oncology was selected to demonstrate the value of social media for mapping influential HCPs. This study reveals the different ways in which potential KOLs in a given therapy area can be found and tracked within the Brandwatch Analytics Platform. In this example, PharmiWeb has helped evaluate and compare the advocacy and regulatory organisations, pharmaceutical manufacturers and medical professionals. SEGMENTING INFLUENCERS “Once identified*, healthcare professionals and scientists/researchers can be further filtered in order to determine their authority, engagement level in the subject and reach. This allows for more targeting tracking of the writing of KOLs, and narrows down to strong candidates for potential engagement through social. In this study, the healthcare/science industry authors were segmented according to three variables: 1 Their speciality 2 The number of posts they’d written about Immuno-Oncology 3 The time period over which they engaged with the subject The platform allowed those listing themselves as Oncologists to be identified and added to an author panel for further tracking. The table below (Fig.3) shows the top 10 Oncologists found discussing Immuno-Oncology over the past 21 months, ranked by the number of followers. The key topics, volume trend and sentiment of this group could now be tracked on an ongoing basis.
  • 14. 14Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com *Twitter profile and profession data gathered using the Brandwatch Demographics feature HCP/Scientist Twitter authors were also segmented according to their engagement level with Immuno-Oncology, both in terms of volume and over time. The chart below shows the activity of the authors shown to be the most important based on both of these points. A filter was applied to show only authors who had Tweeted at least twice about the subject, and had done so in both halves of the time period. Put differently, they had Tweeted at least twice from Jan – Nov 2013, and at least twice between Dec 2013 – Sep 2014 about Immuno-Oncology. The chart below shows the Total potential follower impressions of each of the HCPs identified as the most engaged with Immuno-Oncology. This score is calculated based on the total Twitter followers for each author, multiplied by the number of Tweets posted by that author in the month. This allows brands to track the impact of potential KOLs over time. Once identified, further analysis of KOLs can reveal the most pertinent topics for these groups in comparison with others. Similar identification and filtering practices can create target groups of other KOL types, including journalists or key figures in the market.
  • 15. 15Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
  • 16. 16Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Example Case Two LEVERAGING INSIGHTS TO DRIVE MESSAGING & CHANNEL STRATEGY In this study, the aim was to discover the key author groups interested in HIV treatments, to then inform messaging and channel strategy for relevant brands. The study began by analysing the author groups, allowing the segments to emerge naturally from the data to ascertain the true key interest groups. Once found, these groups were studied in order to understand their key channels and conversation drivers. CHANNEL INSIGHTS Figure 5. shows that conversation about HIV treatments occurred mostly on Twitter. This was particularly the case for HCPs (see the following page for more details on this activity). There was also a group of patients talking openly about their treatment on Twitter, however patients were also the most likely author group to talk in online forums, driven by the ability to speak anonymously. Support workers were the most likely to blog about treatment.
  • 17. 17Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com MESSAGING INSIGHTS Figure 6. shows the overall benefits of treatment most likely to be discussed (for all author groups combined). The treatment benefit that drove the most online conversation was that a person receiving HIV treatment is less likely to transmit the virus (to a partner or in utero). This was discussed 4% more than prolonging the life of the patient, demonstrating the value of social research for checking assumptions. Figure 7. shows the different priorities of the author groups around treatment benefits. Over 60% of online mentions about reducing the likelihood of transmission were actually posted by “other consumers”, suggesting that this could be a strong topic for broader awareness campaigns, but would perhaps not resonate strongly in patient group communications. Patients were the most likely to be concerned with the ability to live a normal life when on effective treatment, even more so than an extended one. Regaining normality could therefore be a message likely to resonate with patient advocacy groups. Combined with the channel insights from the previous page, this data could underpin a wider social engagement strategy.
  • 18. 18Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com GRANULAR HCP INSIGHTS In order to better understand the HCP conversation on Twitter, the authors were split into their specialty groups. The pie chart in Fig.8 shows that almost 75% of mentions were driven by Mental Health Professionals (including therapists and psychiatrists), Nurses and General Practitioners. This suggests that HCPs concerned with patient support/wellbeing could be a key online target group with interest in HIV medication. The topic cloud in Fig.8 shows the key words most frequently used by the HCPs on Twitter. Patient age was a recurring discussion theme, with “babies”, “children”, “adolescents” and “adults” emerging as key associated age groups. The importance of emotional support for patients was underlined (“counselling”), as well as the links between treatment and prevention of HIV. Understanding existing topics of interest can inform the creation of compelling content for the community.
  • 19. 19Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com
  • 20. 20Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Getting Started PharmiWeb and Brandwatch are well placed to help you in your social listening efforts, whether you’re considering your first project or you’re looking to build on a current initiative. Brandwatch Brandwatch is the world’s most sophisticated social listening and intelligence platform, and offers by far the most flexible analytics available on the market. This helps leading healthcare businesses customize the technology to the specific needs of a sector that operates like no other. To see how the Brandwatch Analytics platform can help your organization, arrange a hassle-free product tour by visiting: brandwatch.com/demo PharmiWeb PharmiWeb solutions has a wealth of expertise in the life sciences vertical, helping deliver sector-specific, actionable insights and strategic marketing recommendations. It is a specialist business that combines pharmaceutical sector experience with digital and technology know-how and creative flair and has been serving the life sciences sector since 2003. PharmiWeb currently works with 8 out of the top 10 global pharma companies Working with Brandwatch, PharmiWeb offers bespoke services to pharma organizations, from listening program pilots to best practice training. To understand more about how PharmiWeb can help you take advantage of social listening, get in touch with natasha.gomer@pharmiweb.com.
  • 21. 21Social Listening for the Pharmaceutical Industry | © 2015 Brandwatch.com Appendix METHODOLOGY / LOCATING AES IN ONLINE MENTIONS The Brandwatch Analytics platform using advanced Boolean operators to allow the creation of sophisticated keyword searching. For transparency, we have included an extract of our search query locating Adverse Events (fig 10). Here we have employed 2 techniques to locate AEs. We begin by searching for specific mentions of “side effects” or general words for problem/trouble. We also search for different ways a consumer might indicate that the drug was not having the desired effect: “does nothing” or “no difference”. Finally, we search for the most commonly occurring specific side effects related to this kind of medication (e.g. bloating, fatigue, dizziness). Any of these terms must appear within 15 words of one of our chosen brand names in order to appear in our data. Fig.9 / Diabetes medication brands studied • Actos • Actos • Actos • Actos • Amaryl • Amaryl • Amaryl • Amaryl • Avandia • Avandia • Avandia • Avandia • Byetta • Byetta • Byetta • Byetta • Diabeta • Diabeta • Diabeta • Diabeta • Glucophage • Glucophage • Glucophage • Glucophage Fig. 10 / Adverse Events Search Query Extract ("side effect" OR reaction OR reacted OR problem* OR trouble* OR "didnt work" OR "didn't work" OR "not effective"~1 OR "no effect" OR "no difference" OR "no different" OR "does nothing" OR "doesn't help" OR "didnt help" OR "didn't help" OR "doesnt help" OR "doesn't work" OR "doesnt work" OR "no better" OR "not better"~1 OR "side effects" OR stomach OR rash OR rashes OR "weight gain"~1 OR "weight gaining"~2 OR kidney OR tired* OR fatigu* OR dizz* OR "metal taste"~1 OR "metallic taste"~1 OR gas OR gassy OR bloat* OR diarr* OR (liver NEAR/5 (disease* OR problem* OR pain* OR issue* OR discomfort*)) OR anaemi* OR ((swell* OR swollen*) NEAR/1 (ankle* OR leg* OR feet OR foot)) OR "low blood sugar")) NEAR/15 (I OR me OR my OR myself OR mine OR im OR ive OR her OR his OR their OR friend* OR boyfriend* OR girlfriend* OR husband* OR wife* OR dad OR mum OR dads OR mums OR mom OR moms OR father* OR mother* OR daughter* OR son? OR aunt* OR uncle OR cousin* )