Talk given to cancer support group at St Laurence Catholic Church in Sugar Land, TX

1. Exploring the links: diet, exercise and cancer Brian Sekula

2. Topics Intro Warburg effect Diet Exercise Conclusions and Recommendations

3. What we know… Target for healthy weight right foods exercise

4. You may not know… Hyperinsulinemia metabolic derangement weight (fat) gain cancer, too

5. Warburg effect… Otto Warburg, 1930 Nobel prize, 1931 metabolic derangement cancer tumors Otto Warburg

6. Warburg effect… ???????? to better understand quick lesson in energy

7. Warburg effect… ATP 3 sources glycolysis

8. Warburg effect… Pretty amazing no glucose stop or regress die of starvation “warburg effect” cancer Google this!

9. Warburg effect… Lots of stuff… glycolysis: inefficient dysfunctional mitochondria no glucose = no energy

10. Warburg effect… You may have heard… “sugar feeds cancer” it’s from Warburg effect

11. Diet

12. Nutrition… Simple glucose

13. How do you do this? Simple Avoid / eliminate: sugar grains starches most fruit

14. How do you do this? Eat all you want healthy fats protein vegetables

15. License to go crazy? No! difficult to overeat these foods

16. Exercise

17. Easy, too! Perfect world??? 2-3 d.wk-1 hard the rest? nice walk

18. Want more? Hard workouts Full-body high intensity

19. Conclusions

20. Why it’s important More than making body Fit Strong reduce glucose

21. What we know now Healthy body not about weight fitness body composition metabolism

22. What we know now Warburg effect tumors have metabolic derangement

23. What we know now Warburg effect promising research starve tumors

24. What we know now Warburg effect promising research starve tumors

25. Recommendations Don’t know if I were in your shoes, I’d try it

26. Recommendations Diet Eliminate: sugars grains starches most fruit

27. Recommendations Diet Eliminate: sugars grains starches most fruit

28. Recommendations Exercise 4-5 d.wk-1 2-3 hard the rest walk ~ 30-45 min.

29. Recommendations Others? Stress Sleep

30. Questions?

31. Contact