Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer and ovarian cancer in postmenopausal women. They may also be used off-label to treat or prevent gynaecomastia in men. Aromatase is the enzyme that synthesizes estrogen. As breast and ovarian cancers require estrogen to grow, AIs are taken to either block the production of estrogen or block the action of estrogen on receptors. There are 2 types of aromatase inhibitors (AIs) approved to treat breast cancer: Irreversible steroidal inhibitors Such as exemestane (Aromasin), forms a permanent and deactivating bond with the aromatase enzyme. Non-steroidal inhibitors Such as anastrozole (Arimidex) and letrozole (Femara), inhibit the synthesis of estrogen via reversible competition for the aromatase enzyme. Visit: http://www.researchliquids.com

2. Aromatase
Inhibitors

3.  Aromatase inhibitors (AIs) are a class of drugs used in the
treatment of breast cancer and ovarian
About
cancer in postmenopausal women. They may also be used offlabel to treat or prevent gynaecomastia in men.
Aromatase
Inhibitors
 Aromatase is the enzyme that synthesizes estrogen. As breast and
ovarian cancers require estrogen to grow, AIs are taken to either
block the production of estrogen or block the action of estrogen
on receptors.

4. There are 2 types of aromatase inhibitors (AIs) approved to treat
breast cancer:
Types Of
Aromatase
Inhibitors
Irreversible steroidal inhibitors
 Such as exemestane (Aromasin), forms a permanent and
deactivating bond with the aromatase enzyme.
Non-steroidal inhibitors
 Such as anastrozole (Arimidex) and letrozole (Femara), inhibit the
synthesis of estrogen via reversible competition for the aromatase
enzyme.

5. Exemestane
Product

6. Exemestane
Details:
Exemestane is a steroidal irreversible CYP19 (aromatase) inhibitor.
Exemestane is structurally related to natural androstenedione and
acts as a false CYP19 enzyme substrate. This effect is also known as
"suicide inhibition". Exemestane has been found to inhibit human
placental CYP19. Buy Exemestane of high quality only at Research
Liquids.

7. Description:
Liquid Exemestane is an irreversible steroidal aromatase inhibitor
Exemestane
(IC50 = 20 nM). Destabilizes aromatase and lowers estrogen levels.
Targets: Aromatase

8. Anastrozole
Product

9. Details:
Exemestane
Anastrozole belongs to a class of compounds known as aromatase
inhibitors. An enzyme known as aromatase is responsible for
producing estrogen by converting androgens into estrogen.
Aromatase inhibitors like Anastrozole prevent aromatase from
fulfilling that role by binding to it and rendering it inactive.
Aromatase inhibitors fall into two categories: reversible (such as
letrozole and Anastrozole ) and irreversible; irreversible aromatase
inhibitors permanently bind to the circulating aromatase complex.
Buy Anastrozole of high quality only at Research Liquids.

10. Description:
Exemestane
Liquid Anastrozole is a third-generation nonsteroidal selective
aromatase inhibitor.
Targets: Aromatase

11. Letrozole
Product

12. Letrozole
Details:
Letrozole is a potent, reversible non-steroidal aromatase inhibitor
(IC50 = 11.5 nM). Displays antitumor effects in several animal
models. Suppresses the endogenous aromatase-induced
proliferation of MCF-7 cells. Buy Letrozole of high quality only at
Research Liquids.

13. Description:
Letrozole
Liquid Letrozole is a third generation nonsteroidal CYP19
aromatase inhibitor.
Targets: CYP19