Lifepak products presentation

1. The Birth of Pharmanex
•Director Medicinal
Chemistries, MERCK
•Identified need for quality
control and standards in
unregulated nutritional
industry
•Achieved $50 million/yr in
sales
•Purchased by Pharmanex in
1998 for $135 million

2. Over 125 PHD level Scientists
Disciplines including
• Botanists
• Pharmacognosist
• Natural Product Specialists
• Medicinal, analytical and
process chemists
• Quality control specialists
• Biochemists
• Molecular biologist
• Pharmacologists
• Toxicologists

3. Pharmanex Scientific Advisory Board

4. Brilliant Minds Endorse...
• Lester Packer – Antioxidant Miracle. Father of
antioxidants. “This validates my life’s work.”
• James Rippe, MD - Tufts, Boston (Cardiologist)
• James Balch, MD – author The Prescription for
Nutritional Healing - 8 million copies sold
• Koji Nakanishi – Columbia, Father of Ginkgo
Biloba research
• Carl Dierassi – Stanford, birth control pill.
• Chi - Huey Wong – Scripps Institute, appointed to
the National Academy of Sciences

5. Selection
To locate the botanicals with the most effective health-promoting properties,
Pharmanex employs teams of experts from the United States and Asia. These
teams conduct exhaustive research-compiling, reviewing, and summarizing
historical use and current intelligence about a botanical's properties and health
benefits. Pharmanex also conducts original research to identify new botanicals,
coordinating with noted professionals at Purdue University, Kansas University,
Columbia University, Scripps Research Institute, and Beijing University, among
others. Only botanicals that pass extensive Pharmanex tests for
authenticity, usefulness, and safety are considered.

6. Sourcing
Once Pharmanex decides to proceed with a particular botanical, a team
investigates potential sources of the botanical and conducts exhaustive
analyses on samples from each source. Sources may be domestic or
international and may include Pharmanex cultivation areas in China
and Chile. Pharmanex chooses a supplier based on the quality and
concentration level of the active ingredient(s) present in samples from
that source.

7. Structure
Using state-of-the-art analytical techniques and working in collaboration
with respected universities and laboratories in both China and the United
States, Pharmanex conducts structural analyses of the natural compounds
present in the selected botanical. These analyses isolate and purify
specific chemical structures in standardized extracts, a critical step in
ensuring a safe and effective botanical.

8. Standardization
Wide variations in active ingredients are characteristic of any botanical. For
example, when Pharmanex analyzes potential Ginkgo biloba leaves, studies
reveal the concentrations of active components will vary by as much as 300%
depending on season, climate, soil, method of harvest, storage conditions, and
processing. Pharmanex optimizes the active ingredients of a product through
strict, proprietary standardization processes (to at least one relevant marker
molecule). Each capsule of a Pharmanex product contains the same amount of
each active ingredient.

9. Safety
Pharmanex is leading the way in establishing strict standards to ensure
the safety of its products. Scientists research and document the history of
a product's use and safety. Pharmaceutical-grade tests for the presence of
microbes, toxins, and heavy metals are carried out for all products. The
active ingredient amount used is based on dosages found effective
through clinical trials and is backed by published data on file at
Pharmanex. Each product label details directions for use and
contains appropriate warning information.

10. Substantiation
Pharmanex only makes product claims that have been substantiated
through documented preclinical and clinical studies. Existing clinical
data are reviewed, and when necessary, Pharmanex sponsors studies of
its products. Data from some of these studies are subsequently submitted
to major international journals for review. This adherence to scientific
standards for substantiation helps make Pharmanex a leader in the
natural healthcare product industry.

11. First Supplement with all 3
Certifications!
• NSF (www.nsf.org)
– Exhaustive formulation & toxicology
analysis
– FDA, cGMP, NSF, ANSI compliance
• BSCG (www.bscgi.org)
– Free from 80+ banned substances by
IOC, WADA, USADA, NFL, NCAA
• ConsumerLab.com
(www.consumerlab.com)
– Ingredient verification
– Only MVMS to test and pass in 6
categories

12. Substantiation
As of 2004,
nine of the Pharmanex Products
are now listed in the
Physician’s Desk Reference (PDR)

13. THE NEXT BIG THING
"The amount of ANTIOXIDANTS that you
maintain in your body is directly
proportional to how long you will live.“
Dr. Richard Cutler, Director of the Anti-
Aging Research Department of the National
Institute of Health(NIH), Wash D.C.

14. Fact
The fastest growing market is in
Health and Wellness
which was $300 billion last year
and is projected to rise to
$1 trillion by the year 2010.
Baby boomers are
25% of the population and
represent 50% of the spending.

15. The Problem
Free Radicals are
unstable molecules that
cause cell and DNA damage;
They are a by-product of
metabolism.

16. Indisputable
30,000 Published Papers
Document the link
between
Free Radical Activity
and Disease

17. Eye Health
NIH Studies - .Age-Related Eye Disease Study Research Group (AREDS). A Randomized, Placebo-Controlled, Clinical Trial
of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular
Degeneration and Vision Loss. Arch Ophthalmol 2001;119:1417-1436.
Age-Related Eye Disease Study Research Group (AREDS). A Randomized, Placebo-Controlled, Clinical Trial of High-
Dose Supplementation With Vitamins C and E and Beta Carotene for Age-Related Cataract and Vision Loss. Arch
Ophthalmol. 2001;119:1439-1452.
Packer L. Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and
cataracts. Ann N Y Acad Sci 1994;738:257-264.
Christen WG, Jr. Antioxidants and eye disease. Am J Med 1994;97 Suppl. 3A:14S-17S.
Eye Disease Case-Control Group. Antioxidant status and neovascular age-related macular degeneration. Arch Opthomol
1993;111(1):104-9.
Gerster H. Antioxidant vitamins in cataract prevention. Z Ernahrungswiss 1989;28:56-75.
Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular
degeneration. Eye Disease Case-Control Study Group. JAMA 1994;272:1413-1420.
Snodderly DM, Evidence for protecting against age-related macular degeneration by carotenoids and antioxidant
vitamins. Am J Clin Nutr 1995;62:1448S-1461S.

18. Most of What Kills Us
Degenerative Diseases
 Cancer
 Heart Disease
 Diabetes
 Age Related Macular Degeneration
 Cataracts
 The aging process itself!

19. Aging Symptoms
“You’re not getting older, just your
DNA”
(Headline from an article in Popular Science, August 2002, p.44)

20. All Around Us
Sources:
Sunlight, Stress, Toxins, Pollution,
X-rays, Radioactivity, Airline travel,
Medications
Metabolism – Calories & Oxygen (75K)
Smoking = 10 Billion
free radicals per cigarette!

21. The Solution
Antioxidants combat free
radicals to prevent cell damage
and maintain health; we get
these from fruits, vegetables,
and vitamin supplements

22. No one gets it
In a survey of 21,500
people, not a single person
consumed a 100% of RDA
for the 10 most important
nutrients!
Did you eat 6-10 Servings* of
Fruits and Vegetables Today?
*as recommended by the National Cancer Institute

23. It is now Unanimous…
June 19,
2002
After decades,
the American
Medical
Association
does a 180º turn
RDAs “Enough
to prevent
deficiency, but
not enough to
prevent disease”
“We recommend that ALL ADULTS
take a multi-vitamin daily”
You are now under doctors orders!

24. Which product?
With so many choices, how do
you know which Antioxidant
supplements to buy?
How does a healthcare
professional know what to
recommend to their
patients... and whether it
works or not?

25. The Missing Link
The ability to MEASURE
is the basis of SCIENCE
This has been the missing
link in the nutritional
industry!

26. What if……
April 6, 1992
On Antioxidants vs. Free Radicals
…Antioxidants may one day
revolutionize health care.
…Screening people through a
simple...test to assess how
much damage free radicals
have done to tissue, much as
patients today are screened for
high cholesterol.
Biochemist, William Pryor, director of the
Biodynamics Institute at Louisiana State University

27. “The Future” is NOW!
ANTIOXIDANT LASER SCANNER

28. MAKE NO MISTAKE:
There is nothing else like the
ANTIOXIDANT LASER SCANNER

29. Protected by Patents
Key Patent issued
March 20, 2001
8 Patents Total
in the US,
Europe and Asia

30. Global Exclusive Rights
acquired Global
Exclusive Rights
to this Technology from
the U of U
for $110 Million....
For the next 16 years!

31. Global Exclusive Rights
IT’S THE ONLY ONE OUT
THERE.
This gives Pharmanex a
LEGAL MONOPOLY

32. Simple Physics
A blue light laser is
directed into the palm of
your hand, and in about 3
minutes you see your total
Antioxidant level... Non-invasively!

33. Site of Action
Only Pharmanex can
measure at the
“Site of Action.”
Cell Body:
Site of Action!
Blood and urine
tests can be altered
by a few meals.
It takes 4-6 weeks or
longer for antioxidants to
reach skin cells.

34. Brilliant Minds Endorse...
• Lester Packer – Antioxidant Miracle. Father of
antioxidants. “This validates my life’s work.”
• James Rippe, MD - Tufts, Boston (Cardiologist)
• James Balch, MD – author The Prescription for
Nutritional Healing - 8 million copies sold
• Koji Nakanishi – Columbia, Discovered Ginkgo
Biloba
• Carl Dierassi – Stanford, birth control pill.
• Chi - Huey Wong – Scripps Institute, appointed to
the National Academy of Sciences

35. Everyone
“Everyone should use the
Pharmanex Bio-Photonic
Scanner to learn their Optimal
Body Defense Score. Once you have
your number, work to increase it and
maintain it with a diet rich in fruits,
vegetables and vitamin
supplements”
Lester Packer, PhD. UC Berkeley
As Quoted on CNN/Money.com

36. Widely Acclaimed
•NBC
•CBS
•CNN Money
•Physician’s Desk Reference
•Logan College Of Chiropractic
•Much, much more.

37. Accepted by Scientific
Community
• New York Academy of Sciences, Feb 2003
• Oxygen Club of California, Feb 2003 and Feb 2004
• FASEB/American Society of Nutritional Sciences -
April 2003 and April 2004
• Gordon Research Conference, Jan 2004
• American College of Nutrition, October 2004

38. 2005 American Business Awards
MOST INNOVATIVE PRODUCT
In the United States
ANTIOXIDANT LASER SCANNER

39. How do we RAISE our Antioxidant
Score?

40. Eat Healthier
4 Cups of Green Tea
50 Cups of Mangos
27 Cups of Green Peas
20 Small Apples
16 Large Potatoes
9 Cups of Cooked Rice
21 Slices of White Bread
14 Slices of Whole Wheat Bread
23 Cups of Pineapple
13 Medium Sized Bananas
65 Cups of Asparagus
30 Cups of Milk
10 Cups of Tomatoes
10 Tablespoons of Peanut Butter
59 Slices of Cheddar Cheese
11 ½ Cups of Peanuts
16 Cups of Squash
EVERY
DAY!

41. A better solution
OR TAKE LIFEPAK TWICE A DAY!
(Healthy eating and exercise are still a good idea)

42. LifePak Antioxidants
Vitamin A,C, E,
Selenium, Manganese
Copper, Zinc, Lutein
Lycopene
Alpha-Lipoic Acid
Folic Acid
Phytonutrients
Quercitin
Grape Seed Extract
Green Tea Extract

43. What is LifePak?
A comprehensive,
bioavailable nutritional
wellness supplement
delivering the optimum
amounts of all essential and
beneficial nutrients,
with Pharmaceutical-grade
testing and standardization.
NOT Just Another Multivitamin ....

44. SupplementWatch.com
SupplementWatch rates LifePak #1!
“LifePak has been the subject of two clinical
studies designed to assess the antioxidant
benefits of the product – quite a significant fact
when you consider that we know of NO other
supplement companies that have sponsored
clinical studies on their multivitamin products.”
“We applaud Pharmanex for their efforts in
this regard.”

45. Effect of LifePak Supplementation
19950
26858
29463
33173
45000
40000
35000
30000
25000
20000
15000
10000
5000
0
0 4 8 12
Time (weeks)
V. Low | Low | Mod.| High
p < 0.01 p < 0.01

46. Individual Changes, Days 1-28
45,000
40,000
35,000
30,000
25,000
20,000
15,000
10,000
5,000
0
Day 1 Day 28
n = 25

47. #1 Product
Top Revenue Supplement in the World
Top Supplement certified banned substance
free by the USOC
Shipped directly to each customer
20% - 30% rewards program every month!

48. G3
Ingredients
Gac juice (Momordica cochinchinensis)
Cili juice
Siberian Pineapple
Chinese Lycium
With Highly Bio-Available
Lipocarotenes™

49. Beta-Carotene (mg/g wet wt.)
48
76 79
718
800
700
600
500
400
300
200
100
0
Spinach Carrot Sw.Potato Gac aril
Ishida et al., J Agric Food Chem 52:274, 2004
10 x more
than carrots!

50. Zeaxanthin in Chinese Lycium (mg/g wet wt.)
18
800
1000
900
800
700
600
500
400
300
200
100
0
40 x more than
yellow corn!
Yellow Corn Ch.Lycium

51. Vitamin C in Cili Fruit (mg/100g wet wt.)
30 45 71
2500
2500
2000
1500
1000
500
0
60 x more
than oranges!
Mandarin Orange Kiwi Cili

52. Lycopene (mg/g wet wt.)
31 41 54
2227
2500
2000
1500
1000
500
0
Tomato Watermelon Guava Gac aril
Ishida et al., J Agric Food Chem 52:274, 2004
70 x more
than tomatoes!

53. Pharmanex controls the
world-wide production of
Gac
and
Cili

54. Recorded Benefits
• Increases energy
• Anti-aging properties
• Promotes eye health
• Strengthens Immune System
• Fights cancer
• Improves circulation
• Regulates cholesterol
• Promotes Prostate health
• Facilitates optimal bioavailability of key nutrients
• Promotes skin health
• Promotes vascular health
• Promotes would healing
• Protects skin from UV damage
• Fights heart disease
• Prevents stroke
• Stabilizes blood pressure
• Promotes better digestion
• Promotes prostate health
• Bolsters immune system
• Promotes liver health
• Eases headaches
• Promotes sexual health
• Promotes vitality

55. ABSOLUTE PROOF
FINALLY SOMEONE PUTS THEIR MONEY
WHERE THEIR MOUTH IS!
Free re-scan every 30 days
100% Money Back Guarantee!
Only Pharmanex can provide
on-going measurement and
motivation to every patient!