What: Invitation to join the “All Business Briefing” on current COVID-19 conditions and what to expect in the near future Special Guest Speakers: Orange County Health Department Director Quintana Stewart and Dr. Abhi Mehrotra, Vice Chair, Strategic Initiatives & Operations for UNC Dept. of Emergency Medicine, UNC Health Why: The purpose of this call is to share timely and relevant information on COVID-19 and the Omicron variant to help you and your business navigate the upcoming months. We will discuss vaccination and hospitalization statistics, optimal testing practices, how to slow the spread and what to expect moving forward. When: Tuesday, January 11, 2022 from 3:30pm-4:30pm

1. Orange County
COVID-19 Update
January 11, 2022
Quintana Stewart, MPA
Orange County Health Director

2. COVID-19 in Orange County
As of January 11, 2022
• Transmission rate - HIGH
• 3,001 new cases over past 14 days
• % positive – 19.0% (14 day % positive); NC rate is 30.5%;
• 113 total deaths

3. The Omicron Variant was first detected in North Carolina the week ending December
11, 2021. For the week ending December 25, 2021, the most recent data available,
Omicron represented 40% of sequenced viruses.

4. Omicron Variant
Impact on Infection & Clinical Illness
• Highly transmissible; likely at least two –three times as contagious
as the Delta variant
• Rapidly spreading; estimated to be at least 95% of what is
circulating in Southeastern US region
• Preliminary data suggests less severe disease- affects upper
respiratory track (nose & throat) more than lower respiratory tract
(lungs)
Impact on Vaccines & Therapeutics
• Decreased protection from primary series of vaccination or past
infection
• Boosters provide increase protection. The booster restores vaccine
effectiveness against infection to 75%; boosters reduce risk of
hospitalization by 81%.
• Decreased protection from some therapeutics. Decreased
effectiveness of monoclonal antibodies, except Sotrovimab. Other
Antivirals (remdesivir, molnupiravir, and PAXLOVID) still appear to
be effective.

5. Vaccination in Orange County
As of January 11, 2022

6. Vaccination in Orange County
by Race
As of January 7, 2022

7. Vaccination in Orange County
by Ethnicity
As of January 7, 2022

8. Vaccination in Orange County
by Age
As of January 7, 2022

9. Anticipated Change to County
Mitigation Strategies
• At this time, Elected Officials have not
conveyed plans to implement gathering
limitations, curfew hours, business closures,
etc.
Continue to Recommend:
• Mask
• Vaccination/Booster
• Physical Distancing in public places
• Hand Hygiene

10. Testing
• Strongly Recommended if you have symptoms
• Recommended if you have a known exposure
to a positive COVID case
• Required for some employers if unvaccinated
Resources

11. Testing Resources
• Testing outside of Orange County is acceptable
• Results will be reported to local health
department in County of Residence
• Statewide Reports of delays for results
• NC DHHS At Home Test Kits:
https://covid19.ncdhhs.gov/about-covid-
19/testing/covid-19-test-home-collection-kit-
program

12. Testing Resources

13. Testing Resources

14. New CDC Isolation & Quarantine
Guidance
https://www.cdc.gov/coronavirus/2019-ncov/your-health/quarantine-isolation.html

15. New CDC Isolation & Quarantine
Guidance
https://www.cdc.gov/coronavirus/2019-ncov/your-health/quarantine-isolation.html
For General Public:

16. New CDC Isolation & Quarantine
Guidance
https://www.cdc.gov/coronavirus/2019-ncov/your-health/quarantine-isolation.html

17. The ASK?
• Continue to promote safe environments that
protect all
• Encourage sick employees to stay home
• Encourage vaccination/boosters
• Call the health department if you need
signage or have questions about workplace
cases