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Global Rheumatoid Arthritis Market: Trends and
Opportunities (2013-2018)
Global Rheumatoid Arthritis Market Report
Scope of the report
The report titled “Global Rheumatoid Arthritis Market: Trends and Opportunities (2013-2018)”
provides an in-depth analysis of global rheumatoid arthritis market with special focus on
biologics drugs. It also accesses the key opportunities and underlying trends in the market and
outlines the factors that are and will be driving the growth of the industry in the forecasted
period (2013-18). Further, key drug manufacturers of the global rheumatoid arthritis market
like Abbvie Inc. (Humira), Amgen Inc. (Enbrel), Johnson & Johnson (Remicade), Roche
Holdings AG (Actemra) are profiled in the report.
Company Coverage
Abbvie Inc.
Amgen Inc.
Johnson & Johnson

Roche Holdings AG
Global Rheumatoid Arthritis Market Report
Executive Summary
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that principally attacks synovial joints. It
is one of the most common autoimmune diseases affecting people of all ages and races. RA affects the
lining of joints, causing a painful swelling that can eventually result in bone erosion and joint
deformity. It also leads to stiffness, and redness in the joints. The main factor causing rheumatoid
arthritis remains unknown. However, according to studies around the world some of the genetic and
environmental factors are found to be more probable causers.
Treatment of Rheumatoid Arthritis involves frequent drugs administration as RA is a progressive and
incurable disease. Drugs used for treatment of RA are classified as first line agents- consisting of non
steroidal anti-inflammatory drugs (NSAIDs) and steroids such as glucocorticoids and second line
agents- consisting of disease modifying anti-rheumatic drugs such as chloroquine, gold salts,
penicillamine, cyclosporine, and several biological agents like TNF-α and interleukin-1 inhibitors.
Global rheumatoid arthritis market is driven by increase in incidences of RA patients, global ageing

population and increasing healthcare expenditure by government of various nations. Factors which are
affecting pharmaceutical companies are pricing pressure, patent expiries of RA drugs, high costs of
treatments involved and escalating R&D costs. The market is characterized by use of auto-injectors by
patients for RA treatment, increase in RA cases in women and FDA approvals for RA drugs.
Global Rheumatoid Arthritis Market: Overview
Rheumatoid arthritis, or RA, is a form of chronic inflammatory disorder that typically affects the
small joints of hands and feet. It is an autoimmune disease which occurs when a person’s
immune system mistakenly attacks body's tissues.
Global Rheumatoid Arthritis Market Size, 201012 (US$ Billions)

2010

2011

2012E

Global Rheumatoid Arthritis Market Size
Forecast, 2013E-18E (US$ Billions)

2013E

2014E

2015E

2016E

2017E

2018E

• Market size of global rheumatoid arthritis market is expected to reach to US$ …… billions in
the year 2018, from US$ …… billions in 2012 by growing at a CAGR of………%.
• Growth in the market is due to …………………………………………….
Global Rheumatoid Arthritis Biologics Drugs Market
Global Rheumatoid Arthritis Biologics Drug
Market Size, 2010-12E (US$ Billions)

Global Rheumatoid Arthritis Biologics Drug
Market Share by Types (2013E)
Others
dd%

Enbrel
cc%

2010

2011E

Humira
aa%

B
bb%

2012E

Global Rheumatoid Arthritis Biologics Drug
Market Size Forecast, 2013E-18E (US$ Billions)

Global Rheumatoid Arthritis Biologics Drug
Market Share Forecast (2016E)
Others
nn%
Humira
kk%

Enbrel
mm%

2013E

2014E

2015E

2016E

2017E

2018E

B
jj%
Market Trends
Auto-Injectors for Rheumatoid Arthritis
Treatment

Increase in Rheumatoid Arthritis in
Women

• …………………………………………………….

• …………………………………………………….

• ……………………………………………………

• …………………………………………………….

• ……………………………………………………

• ……………………………………………………

• …………………………………………………..

• …………………………………………………..

FDA Approvals of
Rheumatoid Arthritis
Drugs

Licensing Deals

• ………………………………………
……….

• ………………………………………
……….

• ………………………………………
…………….

• ………………………………………
…………….

• ………………………………………
……

• ………………………………………
……

Rheumatoid
Arthritis
Drugs in R&D Pipeline

• ……………………………………
………….
• ……………………………………
……………….
• ……………………………………
………………
• …………………………….
Table of Contents
1. Executive Summary

5.

2. Rheumatoid Arthritis: An Introduction

Analysis

2.1 Rheumatoid Arthritis: Causes

Global

Rheumatoid

Arthritis

Drug

Market

5.1 Global TNF-α target Drugs Market

2.2 Rheumatoid Arthritis: Symptoms & Diagnosis

5.1.1 Global TNF-α target Market Size by Drugs

2.2.1 Rheumatoid Arthritis: Symptoms

(Actual & Forecast)

2.2.2 Rheumatoid Arthritis: Diagnosis

5.1.2 TNF-α target Market Share by Drugs (Actual &

3. Rheumatoid Arthritis Treatment

Forecast)

3.1 Clinical Evolution of Rheumatoid Arthritis Treatment

5.2 Rheumatoid Arthritis Drugs Market: Regional

3.2 Rheumatoid Arthritis: Drugs Treatment

Analysis

3.2.1 First line agents

5.2.1 Rheumatoid Arthritis Drugs Market Size in the

3.2.2 Second line agents

U.S. (2012)

4. Global Rheumatoid Arthritis Market Analysis

5.2.2 TNFα Blockers Drugs Market Size in the U.S.

4.1 Market Size (Actual & Forecast)

(2012)

4.2 Global Rheumatoid Arthritis Treatment Market

5.2.3 Rheumatoid Arthritis Drugs Market Size in

Analysis

Korea

4.2.1 Global Biologics Drugs Market Size (Actual &6. Global Rheumatoid Arthritis Market: Growth
Forecast)

Drivers & Challenges

4.2.2 Global Rheumatoid Arthritis Biologics Drugs 6.1 Growth Drivers
Market Share (Actual & Forecast)

6.1.1

Increase

in

Incidence

4.2.3 Global TNF-α target Antibody Market Size

Rheumatoid Arthritis

(Actual & Forecast)

of

6.1.2 Global Aging Population
6.1.3 Global Healthcare Expenditure

Patients

with
Table of Contents
6.2 Challenges
6.2.1 Pricing pressure

9.1.3 Business Strategies
9.2 Amgen Inc.

6.2.2 Patent Expiries

9.2.1 Business Overview

6.2.3 High Cost of Treatment

9.2.2 Financial Overview

6.2.4 High R&D Costs

9.2.3 Business Strategies

7. Global Rheumatoid Arthritis Market Trends

9.3 Johnson & Johnson Services Inc.

7.1 Auto-Injectors for Rheumatoid Arthritis Treatment

9.3.1 Business Overview

7.2 Increase in Rheumatoid Arthritis in Women

9.3.2 Financial Overview

7.3 Licensing Deals

9.3.3 Business Strategies

7.4 FDA Approvals of Rheumatoid Arthritis Drugs
7.5 Rheumatoid Arthritis Drugs in R&D Pipeline

9.4 Roche Holdings AG
9.4.1 Business Overview

8. Competitive Landscape

9.4.2 Financial Overview

9. Company Profiles

9.4.3 Business Strategies

9.1 AbbVie Inc. (Abbott Laboratories)
9.1.1 Business Overview
9.1.2 Financial Overview
List of Charts
Figure 1: Normal and Arthritis Joints
Figure 2: Clinical Evolution of Rheumatoid Arthritis Treatment
Figure 3: Rheumatoid Arthritis Drugs Treatment Classification

Figure 4: Global Rheumatoid Arthritis Market Size, 2010-12 (US$ Billions)
Figure 5: Global Rheumatoid Arthritis Market Size Forecast, 2013E-18E (US$ Billions)
Figure 6: Global Rheumatoid Arthritis Biologics Drug Market Size, 2010-12E (US$ Billions)
Figure 7: Global Rheumatoid Arthritis Biologics Drug Market Size Forecast, 2013E-18E (US$ Billions)
Figure 8: Global Rheumatoid Arthritis Biologics Drug Market Share by Types (2013E)
Figure 9: Global Rheumatoid Arthritis Biologics Drug Market Share Forecast (2016E)
Figure 10: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size, 2010-12E
Figure 11: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size Forecast, 2013E-18E
Figure 12: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size by Drug, 2010-12E (US$
Billions)
Figure 13: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size by Drug, 2010-12E (US$
Billions)
Figure 14: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Share by Drugs (2012E)
Figure 15: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Share by Drugs Forecast
(2018E)
Figure 16: Rheumatoid Arthritis Drugs Market Size in the U.S, 2012 (US$ Millions)
List of Charts
Figure 17: TNFα Blockers Drugs Market Size and Share in the U.S., 2012 (US$ Billions)
Figure 18: Rheumatoid Arthritis Drugs Market Size in Korea, 2009-11 (US$ Millions)
Figure 19: Number of Patients of Rheumatoid Arthritis in the U.S., 2010-17E (Billions)
Figure 20: Global Aging Population, 2005-13E (Millions)
Figure 21: Global Healthcare Expenditure, 2005-15E (US$ Trillions)
Table 1: Representative Deals in Global Rheumatoid Arthritis Market
Table 2: FDA-Approved Biologic Agents for Forms of Rheumatoid Arthritis by Indication and Year of Indication

Approval
Table 3: Biologic Rheumatoid Arthritis Treatments in Clinical Development or in the Market (FY12)
Table 4: Major Players in the Rheumatoid Arthritis Market
Table 5: Indications and Boxed Warnings for Biologics Used in the Treatment of Rheumatoid Arthritis
Figure 22: AbbVie Inc. Consolidated Revenue and Humira Sales, 2013Q1-2013Q3 (US$ Billions)
Figure 23: Amgen Inc. Revenue by Business Segment (2012)
Figure 24: Amgen Inc. Consolidated Revenue and Enbrel Sales, 2010-12 (US$ Billions)
Figure 25: Johnson & Johnson Revenue by Business Segment (2012)
Figure 26: Johnson & Johnson Consolidated and Pharmaceutical Segment Revenue, 2010-12 (US$ Billions)
Figure 27: Roche Holdings AG Revenue by Business Segment (2012)
Figure 28: Roche Holdings AG Revenue, 2008-12 (US$ Billions)

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Global Rheumatoid Arthritis Market: Trends and Opportunities (2013-2018) – New Report by Daedal Research

  • 1. Global Rheumatoid Arthritis Market: Trends and Opportunities (2013-2018)
  • 2. Global Rheumatoid Arthritis Market Report Scope of the report The report titled “Global Rheumatoid Arthritis Market: Trends and Opportunities (2013-2018)” provides an in-depth analysis of global rheumatoid arthritis market with special focus on biologics drugs. It also accesses the key opportunities and underlying trends in the market and outlines the factors that are and will be driving the growth of the industry in the forecasted period (2013-18). Further, key drug manufacturers of the global rheumatoid arthritis market like Abbvie Inc. (Humira), Amgen Inc. (Enbrel), Johnson & Johnson (Remicade), Roche Holdings AG (Actemra) are profiled in the report. Company Coverage Abbvie Inc. Amgen Inc. Johnson & Johnson Roche Holdings AG
  • 3. Global Rheumatoid Arthritis Market Report Executive Summary Rheumatoid arthritis (RA) is a chronic inflammatory disorder that principally attacks synovial joints. It is one of the most common autoimmune diseases affecting people of all ages and races. RA affects the lining of joints, causing a painful swelling that can eventually result in bone erosion and joint deformity. It also leads to stiffness, and redness in the joints. The main factor causing rheumatoid arthritis remains unknown. However, according to studies around the world some of the genetic and environmental factors are found to be more probable causers. Treatment of Rheumatoid Arthritis involves frequent drugs administration as RA is a progressive and incurable disease. Drugs used for treatment of RA are classified as first line agents- consisting of non steroidal anti-inflammatory drugs (NSAIDs) and steroids such as glucocorticoids and second line agents- consisting of disease modifying anti-rheumatic drugs such as chloroquine, gold salts, penicillamine, cyclosporine, and several biological agents like TNF-α and interleukin-1 inhibitors. Global rheumatoid arthritis market is driven by increase in incidences of RA patients, global ageing population and increasing healthcare expenditure by government of various nations. Factors which are affecting pharmaceutical companies are pricing pressure, patent expiries of RA drugs, high costs of treatments involved and escalating R&D costs. The market is characterized by use of auto-injectors by patients for RA treatment, increase in RA cases in women and FDA approvals for RA drugs.
  • 4. Global Rheumatoid Arthritis Market: Overview Rheumatoid arthritis, or RA, is a form of chronic inflammatory disorder that typically affects the small joints of hands and feet. It is an autoimmune disease which occurs when a person’s immune system mistakenly attacks body's tissues. Global Rheumatoid Arthritis Market Size, 201012 (US$ Billions) 2010 2011 2012E Global Rheumatoid Arthritis Market Size Forecast, 2013E-18E (US$ Billions) 2013E 2014E 2015E 2016E 2017E 2018E • Market size of global rheumatoid arthritis market is expected to reach to US$ …… billions in the year 2018, from US$ …… billions in 2012 by growing at a CAGR of………%. • Growth in the market is due to …………………………………………….
  • 5. Global Rheumatoid Arthritis Biologics Drugs Market Global Rheumatoid Arthritis Biologics Drug Market Size, 2010-12E (US$ Billions) Global Rheumatoid Arthritis Biologics Drug Market Share by Types (2013E) Others dd% Enbrel cc% 2010 2011E Humira aa% B bb% 2012E Global Rheumatoid Arthritis Biologics Drug Market Size Forecast, 2013E-18E (US$ Billions) Global Rheumatoid Arthritis Biologics Drug Market Share Forecast (2016E) Others nn% Humira kk% Enbrel mm% 2013E 2014E 2015E 2016E 2017E 2018E B jj%
  • 6. Market Trends Auto-Injectors for Rheumatoid Arthritis Treatment Increase in Rheumatoid Arthritis in Women • ……………………………………………………. • ……………………………………………………. • …………………………………………………… • ……………………………………………………. • …………………………………………………… • …………………………………………………… • ………………………………………………….. • ………………………………………………….. FDA Approvals of Rheumatoid Arthritis Drugs Licensing Deals • ……………………………………… ………. • ……………………………………… ………. • ……………………………………… ……………. • ……………………………………… ……………. • ……………………………………… …… • ……………………………………… …… Rheumatoid Arthritis Drugs in R&D Pipeline • …………………………………… …………. • …………………………………… ………………. • …………………………………… ……………… • …………………………….
  • 7. Table of Contents 1. Executive Summary 5. 2. Rheumatoid Arthritis: An Introduction Analysis 2.1 Rheumatoid Arthritis: Causes Global Rheumatoid Arthritis Drug Market 5.1 Global TNF-α target Drugs Market 2.2 Rheumatoid Arthritis: Symptoms & Diagnosis 5.1.1 Global TNF-α target Market Size by Drugs 2.2.1 Rheumatoid Arthritis: Symptoms (Actual & Forecast) 2.2.2 Rheumatoid Arthritis: Diagnosis 5.1.2 TNF-α target Market Share by Drugs (Actual & 3. Rheumatoid Arthritis Treatment Forecast) 3.1 Clinical Evolution of Rheumatoid Arthritis Treatment 5.2 Rheumatoid Arthritis Drugs Market: Regional 3.2 Rheumatoid Arthritis: Drugs Treatment Analysis 3.2.1 First line agents 5.2.1 Rheumatoid Arthritis Drugs Market Size in the 3.2.2 Second line agents U.S. (2012) 4. Global Rheumatoid Arthritis Market Analysis 5.2.2 TNFα Blockers Drugs Market Size in the U.S. 4.1 Market Size (Actual & Forecast) (2012) 4.2 Global Rheumatoid Arthritis Treatment Market 5.2.3 Rheumatoid Arthritis Drugs Market Size in Analysis Korea 4.2.1 Global Biologics Drugs Market Size (Actual &6. Global Rheumatoid Arthritis Market: Growth Forecast) Drivers & Challenges 4.2.2 Global Rheumatoid Arthritis Biologics Drugs 6.1 Growth Drivers Market Share (Actual & Forecast) 6.1.1 Increase in Incidence 4.2.3 Global TNF-α target Antibody Market Size Rheumatoid Arthritis (Actual & Forecast) of 6.1.2 Global Aging Population 6.1.3 Global Healthcare Expenditure Patients with
  • 8. Table of Contents 6.2 Challenges 6.2.1 Pricing pressure 9.1.3 Business Strategies 9.2 Amgen Inc. 6.2.2 Patent Expiries 9.2.1 Business Overview 6.2.3 High Cost of Treatment 9.2.2 Financial Overview 6.2.4 High R&D Costs 9.2.3 Business Strategies 7. Global Rheumatoid Arthritis Market Trends 9.3 Johnson & Johnson Services Inc. 7.1 Auto-Injectors for Rheumatoid Arthritis Treatment 9.3.1 Business Overview 7.2 Increase in Rheumatoid Arthritis in Women 9.3.2 Financial Overview 7.3 Licensing Deals 9.3.3 Business Strategies 7.4 FDA Approvals of Rheumatoid Arthritis Drugs 7.5 Rheumatoid Arthritis Drugs in R&D Pipeline 9.4 Roche Holdings AG 9.4.1 Business Overview 8. Competitive Landscape 9.4.2 Financial Overview 9. Company Profiles 9.4.3 Business Strategies 9.1 AbbVie Inc. (Abbott Laboratories) 9.1.1 Business Overview 9.1.2 Financial Overview
  • 9. List of Charts Figure 1: Normal and Arthritis Joints Figure 2: Clinical Evolution of Rheumatoid Arthritis Treatment Figure 3: Rheumatoid Arthritis Drugs Treatment Classification Figure 4: Global Rheumatoid Arthritis Market Size, 2010-12 (US$ Billions) Figure 5: Global Rheumatoid Arthritis Market Size Forecast, 2013E-18E (US$ Billions) Figure 6: Global Rheumatoid Arthritis Biologics Drug Market Size, 2010-12E (US$ Billions) Figure 7: Global Rheumatoid Arthritis Biologics Drug Market Size Forecast, 2013E-18E (US$ Billions) Figure 8: Global Rheumatoid Arthritis Biologics Drug Market Share by Types (2013E) Figure 9: Global Rheumatoid Arthritis Biologics Drug Market Share Forecast (2016E) Figure 10: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size, 2010-12E Figure 11: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size Forecast, 2013E-18E Figure 12: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size by Drug, 2010-12E (US$ Billions) Figure 13: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Size by Drug, 2010-12E (US$ Billions) Figure 14: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Share by Drugs (2012E) Figure 15: Global TNF-α target Rheumatoid Arthritis Antibody Treatment Market Share by Drugs Forecast (2018E) Figure 16: Rheumatoid Arthritis Drugs Market Size in the U.S, 2012 (US$ Millions)
  • 10. List of Charts Figure 17: TNFα Blockers Drugs Market Size and Share in the U.S., 2012 (US$ Billions) Figure 18: Rheumatoid Arthritis Drugs Market Size in Korea, 2009-11 (US$ Millions) Figure 19: Number of Patients of Rheumatoid Arthritis in the U.S., 2010-17E (Billions) Figure 20: Global Aging Population, 2005-13E (Millions) Figure 21: Global Healthcare Expenditure, 2005-15E (US$ Trillions) Table 1: Representative Deals in Global Rheumatoid Arthritis Market Table 2: FDA-Approved Biologic Agents for Forms of Rheumatoid Arthritis by Indication and Year of Indication Approval Table 3: Biologic Rheumatoid Arthritis Treatments in Clinical Development or in the Market (FY12) Table 4: Major Players in the Rheumatoid Arthritis Market Table 5: Indications and Boxed Warnings for Biologics Used in the Treatment of Rheumatoid Arthritis Figure 22: AbbVie Inc. Consolidated Revenue and Humira Sales, 2013Q1-2013Q3 (US$ Billions) Figure 23: Amgen Inc. Revenue by Business Segment (2012) Figure 24: Amgen Inc. Consolidated Revenue and Enbrel Sales, 2010-12 (US$ Billions) Figure 25: Johnson & Johnson Revenue by Business Segment (2012) Figure 26: Johnson & Johnson Consolidated and Pharmaceutical Segment Revenue, 2010-12 (US$ Billions) Figure 27: Roche Holdings AG Revenue by Business Segment (2012) Figure 28: Roche Holdings AG Revenue, 2008-12 (US$ Billions)