During one lung ventilation (OLV), blood flow is shunted to the non-ventilated lung causing hypoxemia. Anesthetics mildly inhibit hypoxic pulmonary vasoconstriction (HPV), increasing shunt by around 4%. Positioning and techniques like selective lung ventilation and PEEP can optimize ventilation and perfusion matching to minimize hypoxemia during OLV.

1. Physiological Aspects of Hypoxemia During One Lung Ventilation Stanford T. Prescott, MD Staff Anesthesiologist Brooke Army Medical Center

3. Normal Distribution of Perfusion in the Lungs

6. Normal Distribution of Ventilation in the Lungs

7. Normal Distribution of Ventilation in the Lungs

14. Oxygen Transport and Causes of Hypoxemia

20. Physiology of One Lung Ventilation in the Lateral Decubitus Position

22. Physiology of One Lung Ventilation and the Lateral Decubitus Position

28. Physiology of the Lateral Decubitus Position

29. Physiology of the Lateral Decubitus Position

30. Physiology of the Lateral Decubitus Position