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ABA 2005 Talking Points for Tables                                     1


             Exploratory Studies in the Prevention of Autism:
                  An Analysis of Five Successful Cases

                            Philip W. Drash
             Autism Early Intervention & Prevention Center
                            Roger M. Tudor
                        Westfield State College

      Based on our recently published paper, An Analysis of Autism as
a Contingency-Shaped Disorder of Verbal Behavior in The Analysis of
Verbal Behavior (Drash & Tudor, 2004), it appears that behavior
analysis may now be in a position to answer one of the more challenging
questions facing autism professionals, parents, and parent advocates,
“How can autism be prevented?”
      This presentation will analyze five successful cases in the
prevention of autism. The subjects were young children, 1 female and 4
males. All children were originally at high-risk for autism or PDD. The
children initially ranged in age from 1 year, 2 months to 2 years, 10
months. All five children achieved relatively complete recovery. In one
case the intervention was minimal. In all cases the hours of intervention
and the costs were substantially less than required for intensive ABA in-
home therapy.
      The purpose of this paper is to show that it may be possible to
prevent the complex of autistic behaviors in some young children at
high-risk for autism or PDD by using the ABA Prevention Program
described in this paper.

                                Presented at:
              Association for Behavior Analysis, International
            31st Annual Convention, Chicago, IL, May 30, 2005
                             Contact Information:
                        Philip W. Drash, Ph.D., BCBA,
               Autism Early Intervention & Prevention Center
            2901 West Busch Blvd., Suite 807, Tampa, FL 33618
             E-mail: inteldev@aol.com Phone: (813) 936-7183
                                Fax: (813) 936-7184
ABA 2005 Talking Points for Tables                                         2


                      Table 1. Individual Subject Data
      The Individual subject data for the 5 subjects is shown in Table 1.
The 5 children, 1 female and 4 males, ranged in age from 1 year, 2 months to
2 years, 10 months.
      The number of individual Verbal Behavior Therapy sessions per child
per week varied from 1 hour to 3 hours per week. The total number of
therapy sessions per child varied from 27 to 77.
      The duration of therapy for each child varied form 7 months to 12
months. The youngest child, Subject 1, age 1 year, 2 months, received no
direct therapy, only the teaching provided by his mother under our
supervision.
      Evidence of Negative Behavior. Only one of the children, Subject 2,
exhibited a relatively high rate of negative behavior at the beginning of
therapy. Subjects 4 and 5, initially exhibited some mild negative behavior.
      Type of Therapy Used. The type of therapy used in this prevention
program was individual Verbal Behavior Therapy.

                      Table 2. Results of Intervention:
   Gains in Expressive Language Age and Intelligence (ELA and IQ)

       Table 2. presents the results of the prevention program in terms of
gains in ELA and IQ during treatment.

       Number of words spoken at the beginning of therapy (Pre Words).
Three of the five children spoke no words at the beginning of therapy, while
two children initially spoke 25 to 30 words.
       ELA at admission ranged from 11 months to 16 months.
       Gains in ELA During Treatment. The children gained from 21
months to 3 years in ELA during treatment that ranged from 7 months to 12
months.
       Followup ELA. At followup the ELA for three of the five children
was average, while it was low average for two children.
       IQ Data. Although it was not possible to obtain a meaningful IQ at
the outset of therapy, Table 2 shows that by the time of discharge 4 of the 5
children achieved an above average IQ while one obtained an average IQ.
The IQ range at discharge was 98 to 125.
ABA 2005 Talking Points for Tables                                           3


                       Table 3. Levels of Intervention

       Table 3. presents the various levels of intervention and how they
relate to the severity of each child’s symptoms. Time does not permit a
detailed description of all six levels of intervention. However, the levels of
intervention will be briefly summarized by presentation of 3 cases.
       Levels 1 & 2 Minimal Intervention. Levels 1 & 2 consist of very
minimal intervention that can be implemented with younger siblings of
children diagnosed with autism. The younger siblings may or may not
display specific symptoms of autism, but are considered to be at risk on the
basis of having an older sibling with autism.
       Subject 1 is typical of such children. Subject 1 was the younger
brother of a child with autism who was in therapy. He was 1 year, 2 months
of age at intervention and spoke almost no words. The intervention consisted
of recommending to the mother that she and the grandmother, who did much
of the babysitting, immediately begin teaching expressive verbal behavior to
the child, using the same Verbal Behavior Therapy techniques that we had
taught her to use with the older child.
       Levels 3 & 4 Moderate Intervention. This level of intervention is
represented by Subject 2, age 22 months at admission. She also was the
younger sibling of a child diagnosed with severe autism who was in our
treatment program. Unlike Subject 1, this child displayed definite signs of
late-onset autism, including loss of previously acquired language, loss of
social skills, and an extremely high rate of negative behavior, including
temper tantrums and noncompliance. Intervention consisted of teaching the
mother VBT techniques for accelerating acquisition of expressive verbal
behavior and ABA techniques for suppression of negative behavior. The
mother used these techniques at home with her child.
       Levels 5 & 6 Moderate Intervention (#2). This level of intervention
is represented by Subject 3. This child was 2 years, 10 months at admission,
and was the oldest child in the group. He had no speech at admission. He
had been evaluated by a number of specialists both in Boston and Tampa,
but despite his severe language delay, was not diagnosed as autistic because
he was very affectionate and social. Prior to admission, he had been in
speech therapy for a full year with no progress, and was clearly at-risk either
for autism / PDD or for severe language delay. Intervention consisted of 3
sessions of individual VBT therapy per week with the child and
simultaneous ongoing training of the mother. The mother conducted regular
daily teaching sessions with her child at home.
ABA 2005 Talking Points for Tables                                        4


  Table 4. Follow-Up Status of Children in ABA Prevention Program
      As shown in Table 4, three of the five children, S1, S4, & S5 are now
functioning as typical children for age level.
      The two other children, S2 and S3, are functioning as low average for
age, and continue to remain in follow-up status.
      Two of the five children, S4 and S5, have been out of the intervention
program for 5 years and 3 years respectively. Both are now functioning as
typical children in regular classrooms, one in 1st grade and one in 2nd.
Neither child requires any special supports or instruction.


Table 5. A Comparison of the ABA Prevention Program with the ABA
     In-Home Treatment Model in Terms of Duration of Treatment,
     Number of Treatment Hours Per Week, Total Number of
     Treatment Hours Per Year, and Total Cost of Treatment.

       As shown in Table 5, the duration of therapy for the Prevention
Program was one year or less, while the In-home Model often requires 3
years or more.
       The number of treatment hours per week for the Prevention Program
was 1 hour to 3 hours per child. This contrasts markedly with the 30 to 40
hours per week typically required by the In-home Treatment Model.
        The total number of treatment hours per year for the Prevention
Program was 27 hours to 150 hours compared to 1,500 hours to 2,000 hours
for the In-home Treatment Model. The annual number of Prevention hours
were less than 10 % of the In-home Model.
        The annual cost of treatment for one year for the Prevention Program
was $2,700 to $15,000 compared to $30,000 to $40,000 for the In-home
Treatment model. In some cases the cost of the Prevention Program is less
than 10% of the cost for the In-home Model.
        For three years the In-home Model could cost as much as $90,000 to
$100,000, whereas the total cost for the Prevention Program would remain
the same as for the annual cost, that is, $2,700 to $15,000.
       Overall, the ABA Prevention Model is far more cost-effective in
terms of both time and expense than the ABA In-home Treatment Model.
ABA 2005 Talking Points for Tables                                                                               5


                           Table 6. Summary and Conclusions
      l. Prevention of autism in some young children at high-risk for autism
or PDD appears to be possible by using the ABA prevention model
presented in this paper. All five children in this study were initially at high-
risk for autism. After a year or less of treatment, all children were
functioning as average or near average.

      2. The total cost and the total number of therapy hours in this
prevention model are far less than that in the typical ABA In-home treatment
model. In some cases both the cost and time may be 10% or less than that
required in the ABA In-home model.

       3. The three primary components of this prevention program were:
(1) rapid development of age-appropriate expressive verbal behavior by
using Verbal Behavior Therapy as the treatment method.
(2) elimination of negative behaviors (i. e. crying, screaming, temper
tantrums, etc.) that function to prevent acquisition of language.
(3) reinforcement of age-appropriate social behavior.

       4. This study illustrates that there are various levels of intensity of
treatment in the continuum of prevention. The least intensive levels of
intervention require relatively little time and effort when compared with
direct treatment programs.

       5. Differentiating between prevention and direct treatment models is
essential. In direct treatment the diagnosis of autism or PDD is usually
established before treatment begins.
       In the prevention model it is only necessary to establish that the child
exhibits behaviors that place him or her in a high-risk category or that he or
she is in a high-risk category based on epidemiological factors.
       There is no assumption that any one specific child will become
autistic. Rather this is a probability model in which a certain percentage of
the at-risk group will likely be diagnosed as autistic without intervention.

Prevention of autism in some young children at high-risk for autism/PDD appears to be possible by using
the ABA prevention model presented in this paper. All five children in this study were functioning as
average or near average after a year or less of treatment.
2) The total cost and the total number of therapy hours in this prevention model are far less that that in the
ABA in-home treatment model. In some cases both the cost and time may be 10% or less than that
required in the ABA in-home model.
ABA 2005 Talking Points for Tables                                       6



                                 In Conclusion
       We believe that the concept of the prevention of autism is a new and
exciting idea whose time has finally come.
       While the data in this exploratory study are clearly preliminary in
nature, we believe that the ABA Prevention Model presented in this paper,
when fully developed, has the potential for benefiting hundreds and perhaps
thousands of young children at high-risk for autism and their families.
       We recommend that you consider incorporating aspects of this
prevention program as an integral component of your autism treatment
programs.

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Exploratory

  • 1. ABA 2005 Talking Points for Tables 1 Exploratory Studies in the Prevention of Autism: An Analysis of Five Successful Cases Philip W. Drash Autism Early Intervention & Prevention Center Roger M. Tudor Westfield State College Based on our recently published paper, An Analysis of Autism as a Contingency-Shaped Disorder of Verbal Behavior in The Analysis of Verbal Behavior (Drash & Tudor, 2004), it appears that behavior analysis may now be in a position to answer one of the more challenging questions facing autism professionals, parents, and parent advocates, “How can autism be prevented?” This presentation will analyze five successful cases in the prevention of autism. The subjects were young children, 1 female and 4 males. All children were originally at high-risk for autism or PDD. The children initially ranged in age from 1 year, 2 months to 2 years, 10 months. All five children achieved relatively complete recovery. In one case the intervention was minimal. In all cases the hours of intervention and the costs were substantially less than required for intensive ABA in- home therapy. The purpose of this paper is to show that it may be possible to prevent the complex of autistic behaviors in some young children at high-risk for autism or PDD by using the ABA Prevention Program described in this paper. Presented at: Association for Behavior Analysis, International 31st Annual Convention, Chicago, IL, May 30, 2005 Contact Information: Philip W. Drash, Ph.D., BCBA, Autism Early Intervention & Prevention Center 2901 West Busch Blvd., Suite 807, Tampa, FL 33618 E-mail: inteldev@aol.com Phone: (813) 936-7183 Fax: (813) 936-7184
  • 2. ABA 2005 Talking Points for Tables 2 Table 1. Individual Subject Data The Individual subject data for the 5 subjects is shown in Table 1. The 5 children, 1 female and 4 males, ranged in age from 1 year, 2 months to 2 years, 10 months. The number of individual Verbal Behavior Therapy sessions per child per week varied from 1 hour to 3 hours per week. The total number of therapy sessions per child varied from 27 to 77. The duration of therapy for each child varied form 7 months to 12 months. The youngest child, Subject 1, age 1 year, 2 months, received no direct therapy, only the teaching provided by his mother under our supervision. Evidence of Negative Behavior. Only one of the children, Subject 2, exhibited a relatively high rate of negative behavior at the beginning of therapy. Subjects 4 and 5, initially exhibited some mild negative behavior. Type of Therapy Used. The type of therapy used in this prevention program was individual Verbal Behavior Therapy. Table 2. Results of Intervention: Gains in Expressive Language Age and Intelligence (ELA and IQ) Table 2. presents the results of the prevention program in terms of gains in ELA and IQ during treatment. Number of words spoken at the beginning of therapy (Pre Words). Three of the five children spoke no words at the beginning of therapy, while two children initially spoke 25 to 30 words. ELA at admission ranged from 11 months to 16 months. Gains in ELA During Treatment. The children gained from 21 months to 3 years in ELA during treatment that ranged from 7 months to 12 months. Followup ELA. At followup the ELA for three of the five children was average, while it was low average for two children. IQ Data. Although it was not possible to obtain a meaningful IQ at the outset of therapy, Table 2 shows that by the time of discharge 4 of the 5 children achieved an above average IQ while one obtained an average IQ. The IQ range at discharge was 98 to 125.
  • 3. ABA 2005 Talking Points for Tables 3 Table 3. Levels of Intervention Table 3. presents the various levels of intervention and how they relate to the severity of each child’s symptoms. Time does not permit a detailed description of all six levels of intervention. However, the levels of intervention will be briefly summarized by presentation of 3 cases. Levels 1 & 2 Minimal Intervention. Levels 1 & 2 consist of very minimal intervention that can be implemented with younger siblings of children diagnosed with autism. The younger siblings may or may not display specific symptoms of autism, but are considered to be at risk on the basis of having an older sibling with autism. Subject 1 is typical of such children. Subject 1 was the younger brother of a child with autism who was in therapy. He was 1 year, 2 months of age at intervention and spoke almost no words. The intervention consisted of recommending to the mother that she and the grandmother, who did much of the babysitting, immediately begin teaching expressive verbal behavior to the child, using the same Verbal Behavior Therapy techniques that we had taught her to use with the older child. Levels 3 & 4 Moderate Intervention. This level of intervention is represented by Subject 2, age 22 months at admission. She also was the younger sibling of a child diagnosed with severe autism who was in our treatment program. Unlike Subject 1, this child displayed definite signs of late-onset autism, including loss of previously acquired language, loss of social skills, and an extremely high rate of negative behavior, including temper tantrums and noncompliance. Intervention consisted of teaching the mother VBT techniques for accelerating acquisition of expressive verbal behavior and ABA techniques for suppression of negative behavior. The mother used these techniques at home with her child. Levels 5 & 6 Moderate Intervention (#2). This level of intervention is represented by Subject 3. This child was 2 years, 10 months at admission, and was the oldest child in the group. He had no speech at admission. He had been evaluated by a number of specialists both in Boston and Tampa, but despite his severe language delay, was not diagnosed as autistic because he was very affectionate and social. Prior to admission, he had been in speech therapy for a full year with no progress, and was clearly at-risk either for autism / PDD or for severe language delay. Intervention consisted of 3 sessions of individual VBT therapy per week with the child and simultaneous ongoing training of the mother. The mother conducted regular daily teaching sessions with her child at home.
  • 4. ABA 2005 Talking Points for Tables 4 Table 4. Follow-Up Status of Children in ABA Prevention Program As shown in Table 4, three of the five children, S1, S4, & S5 are now functioning as typical children for age level. The two other children, S2 and S3, are functioning as low average for age, and continue to remain in follow-up status. Two of the five children, S4 and S5, have been out of the intervention program for 5 years and 3 years respectively. Both are now functioning as typical children in regular classrooms, one in 1st grade and one in 2nd. Neither child requires any special supports or instruction. Table 5. A Comparison of the ABA Prevention Program with the ABA In-Home Treatment Model in Terms of Duration of Treatment, Number of Treatment Hours Per Week, Total Number of Treatment Hours Per Year, and Total Cost of Treatment. As shown in Table 5, the duration of therapy for the Prevention Program was one year or less, while the In-home Model often requires 3 years or more. The number of treatment hours per week for the Prevention Program was 1 hour to 3 hours per child. This contrasts markedly with the 30 to 40 hours per week typically required by the In-home Treatment Model. The total number of treatment hours per year for the Prevention Program was 27 hours to 150 hours compared to 1,500 hours to 2,000 hours for the In-home Treatment Model. The annual number of Prevention hours were less than 10 % of the In-home Model. The annual cost of treatment for one year for the Prevention Program was $2,700 to $15,000 compared to $30,000 to $40,000 for the In-home Treatment model. In some cases the cost of the Prevention Program is less than 10% of the cost for the In-home Model. For three years the In-home Model could cost as much as $90,000 to $100,000, whereas the total cost for the Prevention Program would remain the same as for the annual cost, that is, $2,700 to $15,000. Overall, the ABA Prevention Model is far more cost-effective in terms of both time and expense than the ABA In-home Treatment Model.
  • 5. ABA 2005 Talking Points for Tables 5 Table 6. Summary and Conclusions l. Prevention of autism in some young children at high-risk for autism or PDD appears to be possible by using the ABA prevention model presented in this paper. All five children in this study were initially at high- risk for autism. After a year or less of treatment, all children were functioning as average or near average. 2. The total cost and the total number of therapy hours in this prevention model are far less than that in the typical ABA In-home treatment model. In some cases both the cost and time may be 10% or less than that required in the ABA In-home model. 3. The three primary components of this prevention program were: (1) rapid development of age-appropriate expressive verbal behavior by using Verbal Behavior Therapy as the treatment method. (2) elimination of negative behaviors (i. e. crying, screaming, temper tantrums, etc.) that function to prevent acquisition of language. (3) reinforcement of age-appropriate social behavior. 4. This study illustrates that there are various levels of intensity of treatment in the continuum of prevention. The least intensive levels of intervention require relatively little time and effort when compared with direct treatment programs. 5. Differentiating between prevention and direct treatment models is essential. In direct treatment the diagnosis of autism or PDD is usually established before treatment begins. In the prevention model it is only necessary to establish that the child exhibits behaviors that place him or her in a high-risk category or that he or she is in a high-risk category based on epidemiological factors. There is no assumption that any one specific child will become autistic. Rather this is a probability model in which a certain percentage of the at-risk group will likely be diagnosed as autistic without intervention. Prevention of autism in some young children at high-risk for autism/PDD appears to be possible by using the ABA prevention model presented in this paper. All five children in this study were functioning as average or near average after a year or less of treatment. 2) The total cost and the total number of therapy hours in this prevention model are far less that that in the ABA in-home treatment model. In some cases both the cost and time may be 10% or less than that required in the ABA in-home model.
  • 6. ABA 2005 Talking Points for Tables 6 In Conclusion We believe that the concept of the prevention of autism is a new and exciting idea whose time has finally come. While the data in this exploratory study are clearly preliminary in nature, we believe that the ABA Prevention Model presented in this paper, when fully developed, has the potential for benefiting hundreds and perhaps thousands of young children at high-risk for autism and their families. We recommend that you consider incorporating aspects of this prevention program as an integral component of your autism treatment programs.