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HEARING
A Frog’s Ear
Human Ear
Hearing: Signals from a Hair Cell
• Hair Cells (cilia) play a vital role in
 hearing.
• Cilia quiver with mechanical vibration of
 sound waves.
• Cells produces brief electrical signals that


  go to brain as acoustic information.
Hair cell bundles
•In 4 long parallel columns on basilar
membrane
•Basilar membrane inside cochlea (snail
shaped structure, size of a pea)
•Last of the 3 bones (the stapes or “stirrup” is
responsible for stimulating hair cells.
The Human Ear or Can you ear me?
Sensitivity and Speed of the Ear


• @16,000 hair cells in human cochlea

• 100-125 million photoreceptors in the eye
• Hair cells more sensitive and faster
 than the eye receptors.
• Hair cells
    can’t be studied easily
    die quickly when taken from lab animals
    Good experiment lasts only 15 minutes
    taken from bullfrogs and mice to be studied
• Microelectrodes used to stimulate and study
 hair cells
• Hair cells (cilia) operate like a light
  switch…..
• From shortest to tallest when pushed
  “on”… opposite for “off”
• Human cilia can turn on & off 20,000
 times per second
• Bats -Whales have frequencies as high as
 200,000 times per second
Auditory system is 1000 times faster than the
                  visual system
 Hair cells in cochlea
 • Hair cells in cochlea are connected to the
 auditory nerve.
Ears not only receive sound but emit them as well.
 A healthy ear emits soft sounds in response to the
 sounds that travel into it. Detectable with sensitive
   microphones, these otoacoustic emissions help
 doctors test newborns' hearing. A deaf ear doesn't
           produce these echoes. (Site)
           Checklist for a Baby’s hearing.
Deafness
•2 - 28 million deaf or hearing
impaired persons in U.S.

•Most born with normal hearing
•Deafness from loud noise, disease,
or old age
•Genetic factors contribute too.
Types of Deafness
• Conductive = damage to middle ear
• Sensorineural = damage to inner
 ear… (a) people don’t hear certain
 frequencies (b) neurons in cochlea
 damaged
• 1 out of every 1000 newborns
  born “profoundly deaf”
  • 1 out of 20 has significant hearing
    loss

    • Deafness associated with over 100
      genetic disorders

      • More than 50% of the time deafness
           in newborn children is genetic
•   One Deafness Gene discovered in 1995
•   Analyzed DNA
•   Work done on a “mutant” mouse
•   Protein mouse chromosome called “myosin” in
    mice equivalent to human chromosome
Synesthesia

            Steffie
           Tomson:
          Synesthesia
          Researcher

           . . . and
           Synesthete
                                      NOVA
Video      Pre-Test for Synesthesia
Smell and the Olfactory System

              • Olfactory System can
         distinguish thousands of odors

• The sense of SMELL is the Oldest and
      most vital part of the brain.
 • Primary mode of communication for most
                  animals
   • Influences reproduction and taste for
                   animals
Smell
• Olfactory neurons die and are replaced
  by new, identical ones.

• *Olfactory neurons are the only ones to
  do this (replace themselves every 28
  Days)
• Learning how the process of smelling works
may lead to treatment for the loss of smell
(Anosmia) due to:    Age    Disease
Your Nose contains
specialized sensory
nerve cells (neurons)
with hairlike fibers
called cilia on one
end.

In the olfactory bulb,
information organized
into patterns that brain
interprets as different
odors.
•VMN -- vomeronasal organ =
special structure in the nose
used for:
     •Detecting phermones
     •Receptors in nose are
     thought to help detect
     special chemical signals
     called pheromones
     •Phermones effect -
     mating and
     social functions in animals
     and humans.
How does scent effect our
    experiences???


The Science of Sex Appeal... or
  what do we see and smell
   about sexual attraction?
      Discovery Channel


  Magic and the Brain

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2012 Hearing & Smell

  • 4. Hearing: Signals from a Hair Cell • Hair Cells (cilia) play a vital role in hearing. • Cilia quiver with mechanical vibration of sound waves. • Cells produces brief electrical signals that go to brain as acoustic information.
  • 5. Hair cell bundles •In 4 long parallel columns on basilar membrane •Basilar membrane inside cochlea (snail shaped structure, size of a pea) •Last of the 3 bones (the stapes or “stirrup” is responsible for stimulating hair cells.
  • 6. The Human Ear or Can you ear me?
  • 7. Sensitivity and Speed of the Ear • @16,000 hair cells in human cochlea • 100-125 million photoreceptors in the eye • Hair cells more sensitive and faster than the eye receptors.
  • 8. • Hair cells  can’t be studied easily  die quickly when taken from lab animals  Good experiment lasts only 15 minutes  taken from bullfrogs and mice to be studied • Microelectrodes used to stimulate and study hair cells
  • 9. • Hair cells (cilia) operate like a light switch….. • From shortest to tallest when pushed “on”… opposite for “off” • Human cilia can turn on & off 20,000 times per second • Bats -Whales have frequencies as high as 200,000 times per second
  • 10. Auditory system is 1000 times faster than the visual system Hair cells in cochlea • Hair cells in cochlea are connected to the auditory nerve. Ears not only receive sound but emit them as well. A healthy ear emits soft sounds in response to the sounds that travel into it. Detectable with sensitive microphones, these otoacoustic emissions help doctors test newborns' hearing. A deaf ear doesn't produce these echoes. (Site) Checklist for a Baby’s hearing.
  • 11.
  • 12. Deafness •2 - 28 million deaf or hearing impaired persons in U.S. •Most born with normal hearing •Deafness from loud noise, disease, or old age •Genetic factors contribute too.
  • 13. Types of Deafness • Conductive = damage to middle ear • Sensorineural = damage to inner ear… (a) people don’t hear certain frequencies (b) neurons in cochlea damaged
  • 14. • 1 out of every 1000 newborns born “profoundly deaf” • 1 out of 20 has significant hearing loss • Deafness associated with over 100 genetic disorders • More than 50% of the time deafness in newborn children is genetic
  • 15. One Deafness Gene discovered in 1995 • Analyzed DNA • Work done on a “mutant” mouse • Protein mouse chromosome called “myosin” in mice equivalent to human chromosome
  • 16. Synesthesia Steffie Tomson: Synesthesia Researcher . . . and Synesthete NOVA Video Pre-Test for Synesthesia
  • 17. Smell and the Olfactory System • Olfactory System can distinguish thousands of odors • The sense of SMELL is the Oldest and most vital part of the brain. • Primary mode of communication for most animals • Influences reproduction and taste for animals
  • 18. Smell
  • 19. • Olfactory neurons die and are replaced by new, identical ones. • *Olfactory neurons are the only ones to do this (replace themselves every 28 Days) • Learning how the process of smelling works may lead to treatment for the loss of smell (Anosmia) due to: Age Disease
  • 20. Your Nose contains specialized sensory nerve cells (neurons) with hairlike fibers called cilia on one end. In the olfactory bulb, information organized into patterns that brain interprets as different odors.
  • 21. •VMN -- vomeronasal organ = special structure in the nose used for: •Detecting phermones •Receptors in nose are thought to help detect special chemical signals called pheromones •Phermones effect - mating and social functions in animals and humans.
  • 22. How does scent effect our experiences??? The Science of Sex Appeal... or what do we see and smell about sexual attraction? Discovery Channel Magic and the Brain